Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_72h_versus_single_gel_72h.class.cls
#double_gel_72h_versus_single_gel_72h_repos
Phenotypeclass.cls#double_gel_72h_versus_single_gel_72h_repos
Upregulated in classsingle_gel_72h
GeneSetDIAB_NEPH_DN
Enrichment Score (ES)-0.5547049
Normalized Enrichment Score (NES)-2.1734912
Nominal p-value0.0
FDR q-value4.987375E-4
FWER p-Value0.0040
Table: GSEA Results Summary



Fig 1: Enrichment plot: DIAB_NEPH_DN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1FGFR2FGFR2
Entrez,  Source
ffer syndrome, Jackson-Weiss syndrome)840.4310.0077No
2GHRGHR
Entrez,  Source
growth hormone receptor2500.2870.0044No
3MECP2MECP2
Entrez,  Source
methyl CpG binding protein 2 (Rett syndrome)3270.2570.0070No
4CYP51A1CYP51A1
Entrez,  Source
cytochrome P450, family 51, subfamily A, polypeptide 13660.2440.0121No
5IGFBP2IGFBP2
Entrez,  Source
insulin-like growth factor binding protein 2, 36kDa4730.2090.0108No
6GNEGNE
Entrez,  Source
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase5990.1860.0074No
7CFLARCFLAR
Entrez,  Source
CASP8 and FADD-like apoptosis regulator7170.1710.0040No
8SDC2SDC2
Entrez,  Source
syndecan 2 (heparan sulfate proteoglycan 1, cell surface-associated, fibroglycan)8170.1610.0017No
9VEGFVEGF
Entrez,  Source
vascular endothelial growth factor9010.1530.0004No
10HSPA5HSPA5
Entrez,  Source
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)9090.1520.0048No
11CYP1B1CYP1B1
Entrez,  Source
cytochrome P450, family 1, subfamily B, polypeptide 110780.138-0.0035No
12TRIM23TRIM23
Entrez,  Source
tripartite motif-containing 2312450.127-0.0120No
13RARRES2RARRES2
Entrez,  Source
retinoic acid receptor responder (tazarotene induced) 215010.113-0.0278No
14TSPYL4TSPYL4
Entrez,  Source
TSPY-like 416910.105-0.0388No
15NPHS1NPHS1
Entrez,  Source
nephrosis 1, congenital, Finnish type (nephrin)17920.101-0.0431No
16OAS1OAS1
Entrez,  Source
2',5'-oligoadenylate synthetase 1, 40/46kDa18500.099-0.0442No
17GULP1GULP1
Entrez,  Source
GULP, engulfment adaptor PTB domain containing 118620.099-0.0418No
18UBE2D2UBE2D2
Entrez,  Source
ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)18640.099-0.0387No
19PBEF1PBEF1
Entrez,  Source
pre-B-cell colony enhancing factor 118970.097-0.0379No
20ACSL3ACSL3
Entrez,  Source
acyl-CoA synthetase long-chain family member 319930.094-0.0421No
21ARHGAP5ARHGAP5
Entrez,  Source
Rho GTPase activating protein 522170.088-0.0563No
22MAPK10MAPK10
Entrez,  Source
mitogen-activated protein kinase 1022610.086-0.0567No
23WWP1WWP1
Entrez,  Source
WW domain containing E3 ubiquitin protein ligase 123060.085-0.0573No
24IRS1IRS1
Entrez,  Source
insulin receptor substrate 123290.084-0.0562No
25SLKSLK
Entrez,  Source
STE20-like kinase (yeast)23870.083-0.0579No
26PTPROPTPRO
Entrez,  Source
protein tyrosine phosphatase, receptor type, O24170.082-0.0574No
27CEBPDCEBPD
Entrez,  Source
CCAAT/enhancer binding protein (C/EBP), delta25670.078-0.0663No
28OPTNOPTN
Entrez,  Source
optineurin25770.077-0.0644No
29CAND2CAND2
Entrez,  Source
cullin-associated and neddylation-dissociated 2 (putative)25880.077-0.0627No
30ARL1ARL1
Entrez,  Source
ADP-ribosylation factor-like 126160.076-0.0623No
31GMFBGMFB
Entrez,  Source
glia maturation factor, beta26360.075-0.0613No
32BMP7BMP7
Entrez,  Source
bone morphogenetic protein 7 (osteogenic protein 1)26690.074-0.0613No
33CDS1CDS1
Entrez,  Source
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 127330.073-0.0637No
34GRK5GRK5
Entrez,  Source
G protein-coupled receptor kinase 527430.073-0.0620No
35ANKRD15ANKRD15
Entrez,  Source
ankyrin repeat domain 1528940.069-0.0712No
36CSDACSDA
Entrez,  Source
cold shock domain protein A29270.068-0.0714No
37TCF21TCF21
Entrez,  Source
transcription factor 2129740.067-0.0728No
38DNAJB9DNAJB9
Entrez,  Source
DnaJ (Hsp40) homolog, subfamily B, member 930360.066-0.0753No
39SUB1SUB1
Entrez,  Source
SUB1 homolog (S. cerevisiae)30480.065-0.0740No
40SACM1LSACM1L
Entrez,  Source
SAC1 suppressor of actin mutations 1-like (yeast)31200.064-0.0773No
41UNGUNG
Entrez,  Source
uracil-DNA glycosylase31610.063-0.0783No
42DNM1LDNM1L
Entrez,  Source
dynamin 1-like31840.063-0.0779No
43CANXCANX
Entrez,  Source
calnexin33550.059-0.0890No
44FYNFYN
Entrez,  Source
FYN oncogene related to SRC, FGR, YES33740.059-0.0884No
45STAT1STAT1
Entrez,  Source
signal transducer and activator of transcription 1, 91kDa34160.058-0.0897No
46PEX14PEX14
Entrez,  Source
peroxisomal biogenesis factor 1435650.054-0.0992No
47UBE2L6UBE2L6
Entrez,  Source
ubiquitin-conjugating enzyme E2L 636620.053-0.1048No
48AKAP11AKAP11
Entrez,  Source
A kinase (PRKA) anchor protein 1137000.052-0.1059No
49CSPG2CSPG2
Entrez,  Source
chondroitin sulfate proteoglycan 2 (versican)37280.051-0.1063No
50TMEM23TMEM23
Entrez,  Source
transmembrane protein 2337670.050-0.1076No
51ADORA1ADORA1
Entrez,  Source
adenosine A1 receptor39510.047-0.1200No
52CASP1CASP1
Entrez,  Source
caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)40760.045-0.1280No
53DPP6DPP6
Entrez,  Source
dipeptidyl-peptidase 641230.044-0.1301No
54KLK7KLK7
Entrez,  Source
kallikrein 7 (chymotryptic, stratum corneum)42200.043-0.1360No
55NAB1NAB1
Entrez,  Source
NGFI-A binding protein 1 (EGR1 binding protein 1)42860.041-0.1396No
56PSMA6PSMA6
Entrez,  Source
proteasome (prosome, macropain) subunit, alpha type, 643180.041-0.1406No
57GRIK2GRIK2
Entrez,  Source
glutamate receptor, ionotropic, kainate 243290.041-0.1401No
58XRCC5XRCC5
Entrez,  Source
X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining; Ku autoantigen, 80kDa)43430.040-0.1397No
59COL4A4COL4A4
Entrez,  Source
collagen, type IV, alpha 443580.040-0.1395No
60NAPGNAPG
Entrez,  Source
N-ethylmaleimide-sensitive factor attachment protein, gamma44670.038-0.1465No
61KLK6KLK6
Entrez,  Source
kallikrein 6 (neurosin, zyme)45080.038-0.1483No
62OTUD4OTUD4
Entrez,  Source
OTU domain containing 445320.037-0.1489No
63PCMT1PCMT1
Entrez,  Source
protein-L-isoaspartate (D-aspartate) O-methyltransferase46700.035-0.1582No
64HPGDHPGD
Entrez,  Source
hydroxyprostaglandin dehydrogenase 15-(NAD)48030.032-0.1672No
65HNRPDLHNRPDL
Entrez,  Source
heterogeneous nuclear ribonucleoprotein D-like48220.032-0.1675No
66TNNT2TNNT2
Entrez,  Source
troponin T type 2 (cardiac)48910.031-0.1717No
67RAD23BRAD23B
Entrez,  Source
RAD23 homolog B (S. cerevisiae)49140.031-0.1724No
68LOXL1LOXL1
Entrez,  Source
lysyl oxidase-like 149740.030-0.1759No
69STX7STX7
Entrez,  Source
syntaxin 752780.025-0.1982No
70ARF6ARF6
Entrez,  Source
ADP-ribosylation factor 653210.024-0.2006No
71ADD3ADD3
Entrez,  Source
adducin 3 (gamma)54030.023-0.2061No
72WT1WT1
Entrez,  Source
Wilms tumor 154080.023-0.2056No
73EXOSC7EXOSC7
Entrez,  Source
exosome component 755390.021-0.2148No
74FNBP1FNBP1
Entrez,  Source
formin binding protein 155720.021-0.2166No
75UGP2UGP2
Entrez,  Source
UDP-glucose pyrophosphorylase 256260.020-0.2200No
76SULF1SULF1
Entrez,  Source
sulfatase 156330.020-0.2198No
77COLQCOLQ
Entrez,  Source
collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase56440.020-0.2199No
78CD164CD164
Entrez,  Source
CD164 molecule, sialomucin56760.019-0.2217No
79ST3GAL6ST3GAL6
Entrez,  Source
ST3 beta-galactoside alpha-2,3-sialyltransferase 657450.018-0.2263No
80BST2BST2
Entrez,  Source
bone marrow stromal cell antigen 257940.017-0.2294No
81PSMA2PSMA2
Entrez,  Source
proteasome (prosome, macropain) subunit, alpha type, 258690.016-0.2345No
82TBCATBCA
Entrez,  Source
tubulin-specific chaperone a59090.016-0.2370No
83PCK1PCK1
Entrez,  Source
phosphoenolpyruvate carboxykinase 1 (soluble)60260.014-0.2454No
84HNRPA1HNRPA1
Entrez,  Source
heterogeneous nuclear ribonucleoprotein A160630.013-0.2477No
85GJA1GJA1
Entrez,  Source
gap junction protein, alpha 1, 43kDa (connexin 43)61200.013-0.2515No
86RHOBTB2RHOBTB2
Entrez,  Source
Rho-related BTB domain containing 261380.012-0.2524No
87TMED10TMED10
Entrez,  Source
transmembrane emp24-like trafficking protein 10 (yeast)61850.012-0.2556No
88MTX2MTX2
Entrez,  Source
metaxin 262060.011-0.2567No
89PTPN7PTPN7
Entrez,  Source
protein tyrosine phosphatase, non-receptor type 763060.009-0.2640No
90NMINMI
Entrez,  Source
N-myc (and STAT) interactor63310.009-0.2655No
91TOB1TOB1
Entrez,  Source
transducer of ERBB2, 165670.006-0.2833No
92DUSP1DUSP1
Entrez,  Source
dual specificity phosphatase 166730.004-0.2911No
93PRDX6PRDX6
Entrez,  Source
peroxiredoxin 667680.003-0.2982No
94TAX1BP1TAX1BP1
Entrez,  Source
Tax1 (human T-cell leukemia virus type I) binding protein 168030.003-0.3007No
95MGAT5MGAT5
Entrez,  Source
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase68140.002-0.3014No
96TOMM20TOMM20
Entrez,  Source
translocase of outer mitochondrial membrane 20 homolog (yeast)7046-0.001-0.3190No
97RHEBRHEB
Entrez,  Source
Ras homolog enriched in brain7054-0.001-0.3195No
98RAB1ARAB1A
Entrez,  Source
RAB1A, member RAS oncogene family7133-0.002-0.3254No
99CMAHCMAH
Entrez,  Source
cytidine monophosphate-N-acetylneuraminic acid hydroxylase (CMP-N-acetylneuraminate monooxygenase)7234-0.004-0.3329No
100PHYHIPPHYHIP
Entrez,  Source
phytanoyl-CoA 2-hydroxylase interacting protein7298-0.005-0.3376No
101LANCL1LANCL1
Entrez,  Source
LanC lantibiotic synthetase component C-like 1 (bacterial)7352-0.005-0.3414No
102SKP1ASKP1A
Entrez,  Source
S-phase kinase-associated protein 1A (p19A)7418-0.006-0.3462No
103SMARCA2SMARCA2
Entrez,  Source
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 27445-0.007-0.3480No
104AIF1AIF1
Entrez,  Source
allograft inflammatory factor 17500-0.007-0.3518No
105GLULGLUL
Entrez,  Source
glutamate-ammonia ligase (glutamine synthetase)7612-0.009-0.3600No
106PPFIA4PPFIA4
Entrez,  Source
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 47620-0.009-0.3602No
107NDNNDN
Entrez,  Source
necdin homolog (mouse)7672-0.010-0.3638No
108XPO1XPO1
Entrez,  Source
exportin 1 (CRM1 homolog, yeast)7735-0.011-0.3682No
109DDNDDN
Entrez,  Source
dendrin7856-0.013-0.3769No
110TSC22D3TSC22D3
Entrez,  Source
TSC22 domain family, member 37885-0.013-0.3786No
111VPS26AVPS26A
Entrez,  Source
vacuolar protein sorting 26 homolog A (yeast)7970-0.015-0.3845No
112CACNB2CACNB2
Entrez,  Source
calcium channel, voltage-dependent, beta 2 subunit8013-0.015-0.3873No
113PTPN11PTPN11
Entrez,  Source
protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1)8096-0.016-0.3930No
114MYO1BMYO1B
Entrez,  Source
myosin IB8141-0.017-0.3958No
115YWHAEYWHAE
Entrez,  Source
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide8149-0.017-0.3958No
116ENPEPENPEP
Entrez,  Source
glutamyl aminopeptidase (aminopeptidase A)8208-0.018-0.3996No
117PARP1PARP1
Entrez,  Source
poly (ADP-ribose) polymerase family, member 18224-0.018-0.4001No
118ITGB5ITGB5
Entrez,  Source
integrin, beta 58308-0.020-0.4058No
119DYRK1ADYRK1A
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A8340-0.020-0.4075No
120ACBD3ACBD3
Entrez,  Source
acyl-Coenzyme A binding domain containing 38347-0.021-0.4073No
121AXLAXL
Entrez,  Source
AXL receptor tyrosine kinase8404-0.021-0.4109No
122GAB2GAB2
Entrez,  Source
GRB2-associated binding protein 28676-0.026-0.4307No
123NBNNBN
Entrez,  Source
nibrin8726-0.027-0.4336No
124HMGN3HMGN3
Entrez,  Source
high mobility group nucleosomal binding domain 38947-0.031-0.4494No
125HNRPCHNRPC
Entrez,  Source
heterogeneous nuclear ribonucleoprotein C (C1/C2)8965-0.032-0.4496No
126PAFAH1B1PAFAH1B1
Entrez,  Source
platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa9229-0.036-0.4685No
127PFN2PFN2
Entrez,  Source
profilin 29269-0.037-0.4703No
128PAK1PAK1
Entrez,  Source
p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)9287-0.038-0.4703No
129DNAJA1DNAJA1
Entrez,  Source
DnaJ (Hsp40) homolog, subfamily A, member 19325-0.038-0.4719No
130TMED5TMED5
Entrez,  Source
transmembrane emp24 protein transport domain containing 59395-0.040-0.4759No
131RDXRDX
Entrez,  Source
radixin9584-0.043-0.4888No
132PDIA3PDIA3
Entrez,  Source
protein disulfide isomerase family A, member 39691-0.045-0.4954No
133APODAPOD
Entrez,  Source
apolipoprotein D9731-0.046-0.4969No
134BIRC2BIRC2
Entrez,  Source
baculoviral IAP repeat-containing 29776-0.047-0.4987No
135ATP2A2ATP2A2
Entrez,  Source
ATPase, Ca++ transporting, cardiac muscle, slow twitch 29784-0.048-0.4977No
136PLCG2PLCG2
Entrez,  Source
phospholipase C, gamma 2 (phosphatidylinositol-specific)9827-0.048-0.4993No
137GMDSGMDS
Entrez,  Source
GDP-mannose 4,6-dehydratase9847-0.049-0.4992No
138SYNPOSYNPO
Entrez,  Source
synaptopodin9931-0.051-0.5039No
139GADD45AGADD45A
Entrez,  Source
growth arrest and DNA-damage-inducible, alpha9946-0.051-0.5033No
140MAGI2MAGI2
Entrez,  Source
membrane associated guanylate kinase, WW and PDZ domain containing 29967-0.051-0.5031No
141CDKN1CCDKN1C
Entrez,  Source
cyclin-dependent kinase inhibitor 1C (p57, Kip2)10008-0.052-0.5045No
142EPS15EPS15
Entrez,  Source
epidermal growth factor receptor pathway substrate 1510115-0.055-0.5108No
143FGF9FGF9
Entrez,  Source
fibroblast growth factor 9 (glia-activating factor)10145-0.055-0.5112No
144AQP3AQP3
Entrez,  Source
aquaporin 3 (Gill blood group)10174-0.056-0.5115No
145PRKAR1APRKAR1A
Entrez,  Source
protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)10251-0.058-0.5154No
146HMGN1HMGN1
Entrez,  Source
high-mobility group nucleosome binding domain 110290-0.059-0.5164No
147PLXNB2PLXNB2
Entrez,  Source
plexin B210304-0.059-0.5154No
148PTHR1PTHR1
Entrez,  Source
parathyroid hormone receptor 110494-0.064-0.5278No
149PLSCR1PLSCR1
Entrez,  Source
phospholipid scramblase 110496-0.064-0.5257No
150SLIT1SLIT1
Entrez,  Source
slit homolog 1 (Drosophila)10513-0.064-0.5249No
151TAPBPTAPBP
Entrez,  Source
TAP binding protein (tapasin)10601-0.067-0.5293No
152SEPT2SEPT2
Entrez,  Source
septin 210614-0.067-0.5280No
153PARD3PARD3
Entrez,  Source
par-3 partitioning defective 3 homolog (C. elegans)10642-0.068-0.5279No
154HSP90AA1HSP90AA1
Entrez,  Source
heat shock protein 90kDa alpha (cytosolic), class A member 110705-0.070-0.5303No
155WARSWARS
Entrez,  Source
tryptophanyl-tRNA synthetase10801-0.073-0.5352No
156PDE4BPDE4B
Entrez,  Source
phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila)10834-0.073-0.5353No
157CTBP1CTBP1
Entrez,  Source
C-terminal binding protein 110835-0.073-0.5329No
158LITAFLITAF
Entrez,  Source
lipopolysaccharide-induced TNF factor10871-0.074-0.5331No
159CREB3L2CREB3L2
Entrez,  Source
cAMP responsive element binding protein 3-like 210974-0.078-0.5384No
160LPLLPL
Entrez,  Source
lipoprotein lipase10988-0.078-0.5368No
161GTF2A2GTF2A2
Entrez,  Source
general transcription factor IIA, 2, 12kDa11025-0.079-0.5369No
162ATXN10ATXN10
Entrez,  Source
ataxin 1011049-0.080-0.5361No
163PPP2CBPPP2CB
Entrez,  Source
protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform11093-0.082-0.5367No
164EXOC7EXOC7
Entrez,  Source
exocyst complex component 711206-0.086-0.5424No
165CASTCAST
Entrez,  Source
calpastatin11239-0.087-0.5420No
166NPTNNPTN
Entrez,  Source
neuroplastin11383-0.094-0.5499No
167DDX17DDX17
Entrez,  Source
DEAD (Asp-Glu-Ala-Asp) box polypeptide 1711390-0.094-0.5472No
168ATXN1ATXN1
Entrez,  Source
ataxin 111431-0.096-0.5471No
169KIF5BKIF5B
Entrez,  Source
kinesin family member 5B11531-0.101-0.5514Yes
170TGFBR3TGFBR3
Entrez,  Source
transforming growth factor, beta receptor III (betaglycan, 300kDa)11551-0.102-0.5495Yes
171ATP6AP2ATP6AP2
Entrez,  Source
ATPase, H+ transporting, lysosomal accessory protein 211554-0.102-0.5464Yes
172RAB21RAB21
Entrez,  Source
RAB21, member RAS oncogene family11573-0.103-0.5444Yes
173BIRC3BIRC3
Entrez,  Source
baculoviral IAP repeat-containing 311637-0.106-0.5457Yes
174NTRK2NTRK2
Entrez,  Source
neurotrophic tyrosine kinase, receptor, type 211666-0.108-0.5444Yes
175ING1ING1
Entrez,  Source
inhibitor of growth family, member 111699-0.109-0.5432Yes
176BCAMBCAM
Entrez,  Source
basal cell adhesion molecule (Lutheran blood group)11705-0.109-0.5401Yes
177YWHAZYWHAZ
Entrez,  Source
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide11724-0.110-0.5378Yes
178GSTA4GSTA4
Entrez,  Source
glutathione S-transferase A411757-0.112-0.5366Yes
179CXADRCXADR
Entrez,  Source
coxsackie virus and adenovirus receptor11788-0.113-0.5352Yes
180PSMB9PSMB9
Entrez,  Source
proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)11801-0.114-0.5324Yes
181AGRINAGRIN
Entrez,  Source
agrin11810-0.114-0.5293Yes
182DAG1DAG1
Entrez,  Source
dystroglycan 1 (dystrophin-associated glycoprotein 1)11814-0.114-0.5258Yes
183CAPN2CAPN2
Entrez,  Source
calpain 2, (m/II) large subunit11927-0.120-0.5304Yes
184NEDD9NEDD9
Entrez,  Source
neural precursor cell expressed, developmentally down-regulated 911950-0.122-0.5282Yes
185DSCR1DSCR1
Entrez,  Source
Down syndrome critical region gene 112036-0.127-0.5305Yes
186RGS10RGS10
Entrez,  Source
regulator of G-protein signalling 1012133-0.133-0.5335Yes
187HTRA1HTRA1
Entrez,  Source
HtrA serine peptidase 112167-0.136-0.5316Yes
188PTGER4PTGER4
Entrez,  Source
prostaglandin E receptor 4 (subtype EP4)12179-0.137-0.5279Yes
189GYG1GYG1
Entrez,  Source
glycogenin 112194-0.139-0.5245Yes
190PTPRDPTPRD
Entrez,  Source
protein tyrosine phosphatase, receptor type, D12216-0.141-0.5215Yes
191PAWRPAWR
Entrez,  Source
PRKC, apoptosis, WT1, regulator12264-0.145-0.5203Yes
192CYR61CYR61
Entrez,  Source
cysteine-rich, angiogenic inducer, 6112269-0.146-0.5159Yes
193PLS3PLS3
Entrez,  Source
plastin 3 (T isoform)12321-0.150-0.5149Yes
194NFASCNFASC
Entrez,  Source
neurofascin homolog (chicken)12327-0.150-0.5103Yes
195CALM2CALM2
Entrez,  Source
calmodulin 2 (phosphorylase kinase, delta)12340-0.152-0.5063Yes
196MSH2MSH2
Entrez,  Source
mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)12432-0.162-0.5079Yes
197ARMCX2ARMCX2
Entrez,  Source
armadillo repeat containing, X-linked 212467-0.166-0.5051Yes
198COL3A1COL3A1
Entrez,  Source
collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant)12541-0.177-0.5049Yes
199PLEKHC1PLEKHC1
Entrez,  Source
pleckstrin homology domain containing, family C (with FERM domain) member 112574-0.181-0.5015Yes
200CBLBCBLB
Entrez,  Source
Cas-Br-M (murine) ecotropic retroviral transforming sequence b12594-0.184-0.4969Yes
201ABI1ABI1
Entrez,  Source
abl-interactor 112600-0.184-0.4913Yes
202CALD1CALD1
Entrez,  Source
caldesmon 112690-0.203-0.4914Yes
203CD47CD47
Entrez,  Source
CD47 molecule12700-0.205-0.4854Yes
204DSTNDSTN
Entrez,  Source
destrin (actin depolymerizing factor)12715-0.208-0.4797Yes
205PRKCIPRKCI
Entrez,  Source
protein kinase C, iota12716-0.208-0.4729Yes
206MYO1EMYO1E
Entrez,  Source
myosin IE12726-0.209-0.4668Yes
207ALDH3B1ALDH3B1
Entrez,  Source
aldehyde dehydrogenase 3 family, member B112784-0.220-0.4640Yes
208BMP2BMP2
Entrez,  Source
bone morphogenetic protein 212792-0.222-0.4572Yes
209PODXLPODXL
Entrez,  Source
podocalyxin-like12834-0.233-0.4528Yes
210CXCL2CXCL2
Entrez,  Source
chemokine (C-X-C motif) ligand 212881-0.245-0.4483Yes
211TLE4TLE4
Entrez,  Source
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)12889-0.247-0.4408Yes
212UGCGUGCG
Entrez,  Source
UDP-glucose ceramide glucosyltransferase12906-0.254-0.4337Yes
213TYRO3TYRO3
Entrez,  Source
TYRO3 protein tyrosine kinase12984-0.284-0.4303Yes
214RAI14RAI14
Entrez,  Source
retinoic acid induced 1412994-0.287-0.4216Yes
215PRKAR2BPRKAR2B
Entrez,  Source
protein kinase, cAMP-dependent, regulatory, type II, beta13042-0.314-0.4149Yes
216TMEM123TMEM123
Entrez,  Source
transmembrane protein 12313062-0.326-0.4057Yes
217CLIC5CLIC5
Entrez,  Source
chloride intracellular channel 513065-0.327-0.3952Yes
218GPNMBGPNMB
Entrez,  Source
glycoprotein (transmembrane) nmb13090-0.347-0.3857Yes
219PLCE1PLCE1
Entrez,  Source
phospholipase C, epsilon 113110-0.363-0.3753Yes
220SERPINE1SERPINE1
Entrez,  Source
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 113125-0.378-0.3640Yes
221SCRN1SCRN1
Entrez,  Source
secernin 113140-0.392-0.3523Yes
222DPYSL3DPYSL3
Entrez,  Source
dihydropyrimidinase-like 313155-0.408-0.3401Yes
223PAMPAM
Entrez,  Source
peptidylglycine alpha-amidating monooxygenase13160-0.412-0.3269Yes
224PDGFAPDGFA
Entrez,  Source
platelet-derived growth factor alpha polypeptide13176-0.433-0.3139Yes
225SCHIP1SCHIP1
Entrez,  Source
schwannomin interacting protein 113180-0.438-0.2998Yes
226CITED2CITED2
Entrez,  Source
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 213211-0.481-0.2864Yes
227SERINC5SERINC5
Entrez,  Source
serine incorporator 513225-0.503-0.2710Yes
228MMEMME
Entrez,  Source
membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase)13226-0.505-0.2545Yes
229TSPAN3TSPAN3
Entrez,  Source
tetraspanin 313247-0.547-0.2382Yes
230CTGFCTGF
Entrez,  Source
connective tissue growth factor13260-0.571-0.2204Yes
231PDLIM5PDLIM5
Entrez,  Source
PDZ and LIM domain 513261-0.575-0.2016Yes
232NDRG1NDRG1
Entrez,  Source
N-myc downstream regulated gene 113266-0.607-0.1821Yes
233MCM6MCM6
Entrez,  Source
MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)13267-0.614-0.1621Yes
234F2RF2R
Entrez,  Source
coagulation factor II (thrombin) receptor13282-0.665-0.1415Yes
235ADMADM
Entrez,  Source
adrenomedullin13287-0.697-0.1190Yes
236GPRC5AGPRC5A
Entrez,  Source
G protein-coupled receptor, family C, group 5, member A13289-0.705-0.0961Yes
237F3F3
Entrez,  Source
coagulation factor III (thromboplastin, tissue factor)13308-0.800-0.0714Yes
238IGFBP7IGFBP7
Entrez,  Source
insulin-like growth factor binding protein 713322-0.989-0.0401Yes
239ANXA1ANXA1
Entrez,  Source
annexin A113336-1.2720.0005Yes
Table: GSEA details [plain text format]



Fig 2: DIAB_NEPH_DN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: DIAB_NEPH_DN: Random ES distribution   
Gene set null distribution of ES for DIAB_NEPH_DN