Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | EGF_HDMEC_UP |
| Enrichment Score (ES) | -0.63625157 |
| Normalized Enrichment Score (NES) | -1.8170712 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.034156725 |
| FWER p-Value | 0.924 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | IGFBP2 | IGFBP2 Entrez, Source | insulin-like growth factor binding protein 2, 36kDa | 473 | 0.209 | 0.0086 | No |
| 2 | DDIT3 | DDIT3 Entrez, Source | DNA-damage-inducible transcript 3 | 1921 | 0.097 | -0.0798 | No |
| 3 | CASP4 | CASP4 Entrez, Source | caspase 4, apoptosis-related cysteine peptidase | 2168 | 0.089 | -0.0794 | No |
| 4 | GNAS | GNAS Entrez, Source | GNAS complex locus | 2815 | 0.071 | -0.1130 | No |
| 5 | CDH2 | CDH2 Entrez, Source | cadherin 2, type 1, N-cadherin (neuronal) | 2940 | 0.068 | -0.1080 | No |
| 6 | TIE1 | TIE1 Entrez, Source | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 | 4890 | 0.031 | -0.2479 | No |
| 7 | RAD23B | RAD23B Entrez, Source | RAD23 homolog B (S. cerevisiae) | 4914 | 0.031 | -0.2431 | No |
| 8 | DAD1 | DAD1 Entrez, Source | defender against cell death 1 | 5314 | 0.024 | -0.2680 | No |
| 9 | GPI | GPI Entrez, Source | glucose phosphate isomerase | 5582 | 0.021 | -0.2837 | No |
| 10 | GRB2 | GRB2 Entrez, Source | growth factor receptor-bound protein 2 | 6191 | 0.011 | -0.3270 | No |
| 11 | GSTM1 | GSTM1 Entrez, Source | glutathione S-transferase M1 | 6456 | 0.007 | -0.3453 | No |
| 12 | TCEB1 | TCEB1 Entrez, Source | transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) | 7156 | -0.002 | -0.3973 | No |
| 13 | RPL6 | RPL6 Entrez, Source | ribosomal protein L6 | 7233 | -0.003 | -0.4023 | No |
| 14 | AXL | AXL Entrez, Source | AXL receptor tyrosine kinase | 8404 | -0.021 | -0.4857 | No |
| 15 | MAP3K11 | MAP3K11 Entrez, Source | mitogen-activated protein kinase kinase kinase 11 | 9043 | -0.033 | -0.5266 | No |
| 16 | PRDX2 | PRDX2 Entrez, Source | peroxiredoxin 2 | 9109 | -0.034 | -0.5243 | No |
| 17 | GADD45A | GADD45A Entrez, Source | growth arrest and DNA-damage-inducible, alpha | 9946 | -0.051 | -0.5763 | No |
| 18 | RELA | RELA Entrez, Source | v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian) | 10137 | -0.055 | -0.5790 | No |
| 19 | PLAUR | PLAUR Entrez, Source | plasminogen activator, urokinase receptor | 10498 | -0.064 | -0.5925 | No |
| 20 | HSP90AA1 | HSP90AA1 Entrez, Source | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 10705 | -0.070 | -0.5932 | No |
| 21 | GPX1 | GPX1 Entrez, Source | glutathione peroxidase 1 | 11279 | -0.089 | -0.6174 | Yes |
| 22 | ITGB1 | ITGB1 Entrez, Source | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 11396 | -0.095 | -0.6062 | Yes |
| 23 | RHOA | RHOA Entrez, Source | ras homolog gene family, member A | 11466 | -0.098 | -0.5906 | Yes |
| 24 | DYNLL1 | DYNLL1 Entrez, Source | dynein, light chain, LC8-type 1 | 11553 | -0.102 | -0.5756 | Yes |
| 25 | CASP3 | CASP3 Entrez, Source | caspase 3, apoptosis-related cysteine peptidase | 11736 | -0.111 | -0.5659 | Yes |
| 26 | TMSB10 | TMSB10 Entrez, Source | thymosin, beta 10 | 11750 | -0.111 | -0.5434 | Yes |
| 27 | HSPB1 | HSPB1 Entrez, Source | heat shock 27kDa protein 1 | 12847 | -0.236 | -0.5760 | Yes |
| 28 | ITGA6 | ITGA6 Entrez, Source | integrin, alpha 6 | 12855 | -0.239 | -0.5261 | Yes |
| 29 | CXCL2 | CXCL2 Entrez, Source | chemokine (C-X-C motif) ligand 2 | 12881 | -0.245 | -0.4763 | Yes |
| 30 | CCND2 | CCND2 Entrez, Source | cyclin D2 | 13080 | -0.340 | -0.4195 | Yes |
| 31 | CCND1 | CCND1 Entrez, Source | cyclin D1 | 13085 | -0.343 | -0.3475 | Yes |
| 32 | CTGF | CTGF Entrez, Source | connective tissue growth factor | 13260 | -0.571 | -0.2400 | Yes |
| 33 | MARCKSL1 | MARCKSL1 Entrez, Source | MARCKS-like 1 | 13330 | -1.167 | 0.0009 | Yes |
