Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | ET743_HELA_UP |
| Enrichment Score (ES) | -0.6791678 |
| Normalized Enrichment Score (NES) | -2.000877 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.006399752 |
| FWER p-Value | 0.163 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | C4BPA | C4BPA Entrez, Source | complement component 4 binding protein, alpha | 176 | 0.331 | 0.0228 | No |
| 2 | CBS | CBS Entrez, Source | cystathionine-beta-synthase | 294 | 0.267 | 0.0431 | No |
| 3 | CFD | CFD Entrez, Source | complement factor D (adipsin) | 1087 | 0.138 | -0.0014 | No |
| 4 | ATF3 | ATF3 Entrez, Source | activating transcription factor 3 | 1413 | 0.118 | -0.0130 | No |
| 5 | NID2 | NID2 Entrez, Source | nidogen 2 (osteonidogen) | 1863 | 0.099 | -0.0359 | No |
| 6 | PHYH | PHYH Entrez, Source | phytanoyl-CoA 2-hydroxylase | 2036 | 0.093 | -0.0388 | No |
| 7 | CASP4 | CASP4 Entrez, Source | caspase 4, apoptosis-related cysteine peptidase | 2168 | 0.089 | -0.0389 | No |
| 8 | FGG | FGG Entrez, Source | fibrinogen gamma chain | 2208 | 0.088 | -0.0323 | No |
| 9 | DUSP5 | DUSP5 Entrez, Source | dual specificity phosphatase 5 | 2225 | 0.087 | -0.0240 | No |
| 10 | DDR2 | DDR2 Entrez, Source | discoidin domain receptor family, member 2 | 3797 | 0.050 | -0.1366 | No |
| 11 | ASNS | ASNS Entrez, Source | asparagine synthetase | 4245 | 0.042 | -0.1657 | No |
| 12 | GARS | GARS Entrez, Source | glycyl-tRNA synthetase | 4370 | 0.040 | -0.1706 | No |
| 13 | NUCB2 | NUCB2 Entrez, Source | nucleobindin 2 | 5371 | 0.024 | -0.2432 | No |
| 14 | EXOSC7 | EXOSC7 Entrez, Source | exosome component 7 | 5539 | 0.021 | -0.2535 | No |
| 15 | PROS1 | PROS1 Entrez, Source | protein S (alpha) | 6244 | 0.011 | -0.3053 | No |
| 16 | TGFBI | TGFBI Entrez, Source | transforming growth factor, beta-induced, 68kDa | 6461 | 0.007 | -0.3208 | No |
| 17 | CYP19A1 | CYP19A1 Entrez, Source | cytochrome P450, family 19, subfamily A, polypeptide 1 | 6596 | 0.005 | -0.3303 | No |
| 18 | CASP9 | CASP9 Entrez, Source | caspase 9, apoptosis-related cysteine peptidase | 6861 | 0.002 | -0.3499 | No |
| 19 | FOLR1 | FOLR1 Entrez, Source | folate receptor 1 (adult) | 6957 | 0.000 | -0.3570 | No |
| 20 | IL6 | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 7239 | -0.004 | -0.3777 | No |
| 21 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 8319 | -0.020 | -0.4567 | No |
| 22 | CXCR4 | CXCR4 Entrez, Source | chemokine (C-X-C motif) receptor 4 | 9737 | -0.046 | -0.5581 | No |
| 23 | GADD45A | GADD45A Entrez, Source | growth arrest and DNA-damage-inducible, alpha | 9946 | -0.051 | -0.5682 | No |
| 24 | AES | AES Entrez, Source | amino-terminal enhancer of split | 10196 | -0.057 | -0.5808 | No |
| 25 | ARL6IP1 | ARL6IP1 Entrez, Source | ADP-ribosylation factor-like 6 interacting protein 1 | 10457 | -0.063 | -0.5934 | No |
| 26 | IL18 | IL18 Entrez, Source | interleukin 18 (interferon-gamma-inducing factor) | 11246 | -0.088 | -0.6431 | No |
| 27 | PRG1 | PRG1 Entrez, Source | proteoglycan 1, secretory granule | 11588 | -0.104 | -0.6575 | No |
| 28 | GSTA4 | GSTA4 Entrez, Source | glutathione S-transferase A4 | 11757 | -0.112 | -0.6580 | No |
| 29 | ANXA4 | ANXA4 Entrez, Source | annexin A4 | 12040 | -0.127 | -0.6653 | Yes |
| 30 | CLU | CLU Entrez, Source | clusterin | 12046 | -0.128 | -0.6517 | Yes |
| 31 | CSRP2 | CSRP2 Entrez, Source | cysteine and glycine-rich protein 2 | 12164 | -0.135 | -0.6458 | Yes |
| 32 | CLDN7 | CLDN7 Entrez, Source | claudin 7 | 12546 | -0.178 | -0.6551 | Yes |
| 33 | CLIC4 | CLIC4 Entrez, Source | chloride intracellular channel 4 | 12577 | -0.181 | -0.6376 | Yes |
| 34 | UGCG | UGCG Entrez, Source | UDP-glucose ceramide glucosyltransferase | 12906 | -0.254 | -0.6346 | Yes |
| 35 | MYH10 | MYH10 Entrez, Source | myosin, heavy chain 10, non-muscle | 12969 | -0.279 | -0.6088 | Yes |
| 36 | GPNMB | GPNMB Entrez, Source | glycoprotein (transmembrane) nmb | 13090 | -0.347 | -0.5800 | Yes |
| 37 | CD44 | CD44 Entrez, Source | CD44 molecule (Indian blood group) | 13174 | -0.431 | -0.5393 | Yes |
| 38 | EML2 | EML2 Entrez, Source | echinoderm microtubule associated protein like 2 | 13178 | -0.436 | -0.4920 | Yes |
| 39 | RGS2 | RGS2 Entrez, Source | regulator of G-protein signalling 2, 24kDa | 13321 | -0.988 | -0.3951 | Yes |
| 40 | IGFBP7 | IGFBP7 Entrez, Source | insulin-like growth factor binding protein 7 | 13322 | -0.989 | -0.2873 | Yes |
| 41 | ANXA1 | ANXA1 Entrez, Source | annexin A1 | 13336 | -1.272 | -0.1497 | Yes |
| 42 | CPE | CPE Entrez, Source | carboxypeptidase E | 13337 | -1.377 | 0.0004 | Yes |
