Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | FATTY_ACID_METABOLISM |
| Enrichment Score (ES) | 0.6554947 |
| Normalized Enrichment Score (NES) | 2.2764018 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FABP1 | FABP1 Entrez, Source | fatty acid binding protein 1, liver | 2 | 1.112 | 0.1143 | Yes |
| 2 | EHHADH | EHHADH Entrez, Source | enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase | 6 | 0.908 | 0.2075 | Yes |
| 3 | ADH7 | ADH7 Entrez, Source | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide | 53 | 0.495 | 0.2549 | Yes |
| 4 | ACOX2 | ACOX2 Entrez, Source | acyl-Coenzyme A oxidase 2, branched chain | 95 | 0.419 | 0.2950 | Yes |
| 5 | FASN | FASN Entrez, Source | fatty acid synthase | 101 | 0.417 | 0.3375 | Yes |
| 6 | ACAA2 | ACAA2 Entrez, Source | acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase) | 135 | 0.374 | 0.3735 | Yes |
| 7 | ACAT2 | ACAT2 Entrez, Source | acetyl-Coenzyme A acetyltransferase 2 (acetoacetyl Coenzyme A thiolase) | 144 | 0.362 | 0.4101 | Yes |
| 8 | ADHFE1 | ADHFE1 Entrez, Source | alcohol dehydrogenase, iron containing, 1 | 163 | 0.343 | 0.4440 | Yes |
| 9 | CPT2 | CPT2 Entrez, Source | carnitine palmitoyltransferase II | 207 | 0.307 | 0.4723 | Yes |
| 10 | ACOX1 | ACOX1 Entrez, Source | acyl-Coenzyme A oxidase 1, palmitoyl | 266 | 0.281 | 0.4969 | Yes |
| 11 | CYP51A1 | CYP51A1 Entrez, Source | cytochrome P450, family 51, subfamily A, polypeptide 1 | 366 | 0.244 | 0.5145 | Yes |
| 12 | CYP1A2 | CYP1A2 Entrez, Source | cytochrome P450, family 1, subfamily A, polypeptide 2 | 390 | 0.235 | 0.5369 | Yes |
| 13 | SC4MOL | SC4MOL Entrez, Source | sterol-C4-methyl oxidase-like | 444 | 0.218 | 0.5553 | Yes |
| 14 | FAAH | FAAH Entrez, Source | fatty acid amide hydrolase | 553 | 0.192 | 0.5669 | Yes |
| 15 | ACAT1 | ACAT1 Entrez, Source | acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase) | 560 | 0.191 | 0.5861 | Yes |
| 16 | ACSL1 | ACSL1 Entrez, Source | acyl-CoA synthetase long-chain family member 1 | 609 | 0.185 | 0.6015 | Yes |
| 17 | ECHS1 | ECHS1 Entrez, Source | enoyl Coenzyme A hydratase, short chain, 1, mitochondrial | 633 | 0.182 | 0.6185 | Yes |
| 18 | CPT1A | CPT1A Entrez, Source | carnitine palmitoyltransferase 1A (liver) | 1046 | 0.140 | 0.6019 | Yes |
| 19 | ADH1A | ADH1A Entrez, Source | alcohol dehydrogenase 1A (class I), alpha polypeptide | 1116 | 0.136 | 0.6107 | Yes |
| 20 | PECI | PECI Entrez, Source | peroxisomal D3,D2-enoyl-CoA isomerase | 1151 | 0.133 | 0.6219 | Yes |
| 21 | PPARA | PPARA Entrez, Source | peroxisome proliferative activated receptor, alpha | 1252 | 0.127 | 0.6274 | Yes |
| 22 | CYP2E1 | CYP2E1 Entrez, Source | cytochrome P450, family 2, subfamily E, polypeptide 1 | 1369 | 0.121 | 0.6310 | Yes |
| 23 | ACADSB | ACADSB Entrez, Source | acyl-Coenzyme A dehydrogenase, short/branched chain | 1480 | 0.114 | 0.6345 | Yes |
| 24 | ACSL5 | ACSL5 Entrez, Source | acyl-CoA synthetase long-chain family member 5 | 1606 | 0.109 | 0.6363 | Yes |
| 25 | PECR | PECR Entrez, Source | peroxisomal trans-2-enoyl-CoA reductase | 1801 | 0.101 | 0.6321 | Yes |
| 26 | ABCD2 | ABCD2 Entrez, Source | ATP-binding cassette, sub-family D (ALD), member 2 | 1926 | 0.096 | 0.6327 | Yes |
| 27 | ACSL3 | ACSL3 Entrez, Source | acyl-CoA synthetase long-chain family member 3 | 1993 | 0.094 | 0.6374 | Yes |
| 28 | ADH6 | ADH6 Entrez, Source | alcohol dehydrogenase 6 (class V) | 2053 | 0.092 | 0.6425 | Yes |
| 29 | HADHA | HADHA Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit | 2174 | 0.089 | 0.6426 | Yes |
| 30 | ALDH1A1 | ALDH1A1 Entrez, Source | aldehyde dehydrogenase 1 family, member A1 | 2239 | 0.087 | 0.6467 | Yes |
| 31 | CYP1A1 | CYP1A1 Entrez, Source | cytochrome P450, family 1, subfamily A, polypeptide 1 | 2351 | 0.084 | 0.6470 | Yes |
| 32 | DHRS3 | DHRS3 Entrez, Source | dehydrogenase/reductase (SDR family) member 3 | 2353 | 0.084 | 0.6555 | Yes |
| 33 | FABP2 | FABP2 Entrez, Source | fatty acid binding protein 2, intestinal | 2972 | 0.067 | 0.6159 | No |
| 34 | ACOX3 | ACOX3 Entrez, Source | acyl-Coenzyme A oxidase 3, pristanoyl | 3046 | 0.066 | 0.6171 | No |
| 35 | GNPAT | GNPAT Entrez, Source | glyceronephosphate O-acyltransferase | 3398 | 0.058 | 0.5967 | No |
| 36 | ACSL4 | ACSL4 Entrez, Source | acyl-CoA synthetase long-chain family member 4 | 3612 | 0.053 | 0.5862 | No |
| 37 | ADH4 | ADH4 Entrez, Source | alcohol dehydrogenase 4 (class II), pi polypeptide | 3800 | 0.050 | 0.5772 | No |
| 38 | DCI | DCI Entrez, Source | dodecenoyl-Coenzyme A delta isomerase (3,2 trans-enoyl-Coenzyme A isomerase) | 4167 | 0.043 | 0.5541 | No |
| 39 | ACADM | ACADM Entrez, Source | acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain | 4299 | 0.041 | 0.5485 | No |
| 40 | HADHB | HADHB Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit | 4675 | 0.035 | 0.5238 | No |
| 41 | LIPE | LIPE Entrez, Source | lipase, hormone-sensitive | 4794 | 0.033 | 0.5183 | No |
| 42 | ALDH3A2 | ALDH3A2 Entrez, Source | aldehyde dehydrogenase 3 family, member A2 | 4819 | 0.032 | 0.5198 | No |
| 43 | ALDH1B1 | ALDH1B1 Entrez, Source | aldehyde dehydrogenase 1 family, member B1 | 5218 | 0.026 | 0.4925 | No |
| 44 | ALDH1A2 | ALDH1A2 Entrez, Source | aldehyde dehydrogenase 1 family, member A2 | 5520 | 0.021 | 0.4721 | No |
| 45 | ACADL | ACADL Entrez, Source | acyl-Coenzyme A dehydrogenase, long chain | 5812 | 0.017 | 0.4520 | No |
| 46 | ACADS | ACADS Entrez, Source | acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain | 5886 | 0.016 | 0.4481 | No |
| 47 | ALDH2 | ALDH2 Entrez, Source | aldehyde dehydrogenase 2 family (mitochondrial) | 6175 | 0.012 | 0.4276 | No |
| 48 | CYP19A1 | CYP19A1 Entrez, Source | cytochrome P450, family 19, subfamily A, polypeptide 1 | 6596 | 0.005 | 0.3966 | No |
| 49 | CYP2C9 | CYP2C9 Entrez, Source | cytochrome P450, family 2, subfamily C, polypeptide 9 | 6753 | 0.003 | 0.3851 | No |
| 50 | SDS | SDS Entrez, Source | serine dehydratase | 8683 | -0.026 | 0.2426 | No |
| 51 | ALDH3A1 | ALDH3A1 Entrez, Source | aldehyde dehydrogenase 3 family, memberA1 | 9824 | -0.048 | 0.1618 | No |
| 52 | CYP3A4 | CYP3A4 Entrez, Source | cytochrome P450, family 3, subfamily A, polypeptide 4 | 10311 | -0.059 | 0.1313 | No |
| 53 | ALDH9A1 | ALDH9A1 Entrez, Source | aldehyde dehydrogenase 9 family, member A1 | 10674 | -0.069 | 0.1112 | No |
| 54 | LPL | LPL Entrez, Source | lipoprotein lipase | 10988 | -0.078 | 0.0956 | No |
| 55 | CYP4B1 | CYP4B1 Entrez, Source | cytochrome P450, family 4, subfamily B, polypeptide 1 | 11195 | -0.086 | 0.0889 | No |
| 56 | CROT | CROT Entrez, Source | carnitine O-octanoyltransferase | 11691 | -0.109 | 0.0629 | No |
| 57 | ASAH1 | ASAH1 Entrez, Source | N-acylsphingosine amidohydrolase (acid ceramidase) 1 | 12353 | -0.153 | 0.0289 | No |
| 58 | FABP7 | FABP7 Entrez, Source | fatty acid binding protein 7, brain | 13182 | -0.442 | 0.0120 | No |
