Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | FERRANDO_MLL_T_ALL_UP |
| Enrichment Score (ES) | -0.53755397 |
| Normalized Enrichment Score (NES) | -1.6983699 |
| Nominal p-value | 0.005376344 |
| FDR q-value | 0.06258472 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FGR | FGR Entrez, Source | Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog | 226 | 0.296 | 0.0363 | No |
| 2 | HYOU1 | HYOU1 Entrez, Source | hypoxia up-regulated 1 | 540 | 0.194 | 0.0478 | No |
| 3 | SLC35B1 | SLC35B1 Entrez, Source | solute carrier family 35, member B1 | 1780 | 0.102 | -0.0271 | No |
| 4 | TIAM1 | TIAM1 Entrez, Source | T-cell lymphoma invasion and metastasis 1 | 1889 | 0.098 | -0.0176 | No |
| 5 | AKAP1 | AKAP1 Entrez, Source | A kinase (PRKA) anchor protein 1 | 2000 | 0.094 | -0.0090 | No |
| 6 | SSR4 | SSR4 Entrez, Source | signal sequence receptor, delta (translocon-associated protein delta) | 2826 | 0.071 | -0.0583 | No |
| 7 | CSDA | CSDA Entrez, Source | cold shock domain protein A | 2927 | 0.068 | -0.0535 | No |
| 8 | USF2 | USF2 Entrez, Source | upstream transcription factor 2, c-fos interacting | 3449 | 0.057 | -0.0825 | No |
| 9 | PPT2 | PPT2 Entrez, Source | palmitoyl-protein thioesterase 2 | 4009 | 0.046 | -0.1162 | No |
| 10 | MBOAT5 | MBOAT5 Entrez, Source | membrane bound O-acyltransferase domain containing 5 | 4148 | 0.044 | -0.1187 | No |
| 11 | NFIL3 | NFIL3 Entrez, Source | nuclear factor, interleukin 3 regulated | 4177 | 0.043 | -0.1130 | No |
| 12 | SLC7A5 | SLC7A5 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 | 4470 | 0.038 | -0.1281 | No |
| 13 | LAPTM5 | LAPTM5 Entrez, Source | lysosomal associated multispanning membrane protein 5 | 4666 | 0.035 | -0.1365 | No |
| 14 | IL2RG | IL2RG Entrez, Source | interleukin 2 receptor, gamma (severe combined immunodeficiency) | 5243 | 0.025 | -0.1753 | No |
| 15 | NUCB2 | NUCB2 Entrez, Source | nucleobindin 2 | 5371 | 0.024 | -0.1806 | No |
| 16 | BTG1 | BTG1 Entrez, Source | B-cell translocation gene 1, anti-proliferative | 5391 | 0.023 | -0.1778 | No |
| 17 | GDI1 | GDI1 Entrez, Source | GDP dissociation inhibitor 1 | 5466 | 0.022 | -0.1794 | No |
| 18 | CX3CR1 | CX3CR1 Entrez, Source | chemokine (C-X3-C motif) receptor 1 | 5524 | 0.021 | -0.1798 | No |
| 19 | ADCYAP1 | ADCYAP1 Entrez, Source | adenylate cyclase activating polypeptide 1 (pituitary) | 5921 | 0.015 | -0.2068 | No |
| 20 | TCF4 | TCF4 Entrez, Source | transcription factor 4 | 5953 | 0.015 | -0.2065 | No |
| 21 | DDX5 | DDX5 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 | 6462 | 0.007 | -0.2435 | No |
| 22 | LCP2 | LCP2 Entrez, Source | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | 6665 | 0.004 | -0.2579 | No |
| 23 | RALGDS | RALGDS Entrez, Source | ral guanine nucleotide dissociation stimulator | 6723 | 0.004 | -0.2615 | No |
| 24 | VDAC1 | VDAC1 Entrez, Source | voltage-dependent anion channel 1 | 7242 | -0.004 | -0.2998 | No |
| 25 | PLEC1 | PLEC1 Entrez, Source | plectin 1, intermediate filament binding protein 500kDa | 7482 | -0.007 | -0.3165 | No |
| 26 | GATA3 | GATA3 Entrez, Source | GATA binding protein 3 | 8231 | -0.019 | -0.3695 | No |
| 27 | SNRPN | SNRPN Entrez, Source | small nuclear ribonucleoprotein polypeptide N | 8412 | -0.022 | -0.3791 | No |
| 28 | SELL | SELL Entrez, Source | selectin L (lymphocyte adhesion molecule 1) | 8867 | -0.029 | -0.4080 | No |
| 29 | PRDX2 | PRDX2 Entrez, Source | peroxiredoxin 2 | 9109 | -0.034 | -0.4200 | No |
| 30 | PRDX1 | PRDX1 Entrez, Source | peroxiredoxin 1 | 9564 | -0.043 | -0.4464 | No |
| 31 | STAT3 | STAT3 Entrez, Source | signal transducer and activator of transcription 3 (acute-phase response factor) | 9982 | -0.052 | -0.4685 | No |
| 32 | RELA | RELA Entrez, Source | v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian) | 10137 | -0.055 | -0.4701 | No |
| 33 | FCGRT | FCGRT Entrez, Source | Fc fragment of IgG, receptor, transporter, alpha | 10155 | -0.056 | -0.4614 | No |
| 34 | CTSH | CTSH Entrez, Source | cathepsin H | 10687 | -0.069 | -0.4888 | No |
| 35 | SMAD1 | SMAD1 Entrez, Source | SMAD, mothers against DPP homolog 1 (Drosophila) | 10761 | -0.072 | -0.4814 | No |
| 36 | GPIAP1 | GPIAP1 Entrez, Source | GPI-anchored membrane protein 1 | 11107 | -0.082 | -0.4926 | No |
| 37 | IFITM2 | IFITM2 Entrez, Source | interferon induced transmembrane protein 2 (1-8D) | 11680 | -0.108 | -0.5162 | Yes |
| 38 | SERINC3 | SERINC3 Entrez, Source | serine incorporator 3 | 11857 | -0.117 | -0.5084 | Yes |
| 39 | CBX3 | CBX3 Entrez, Source | chromobox homolog 3 (HP1 gamma homolog, Drosophila) | 12246 | -0.143 | -0.5117 | Yes |
| 40 | BIN1 | BIN1 Entrez, Source | bridging integrator 1 | 12397 | -0.157 | -0.4947 | Yes |
| 41 | CBLB | CBLB Entrez, Source | Cas-Br-M (murine) ecotropic retroviral transforming sequence b | 12594 | -0.184 | -0.4764 | Yes |
| 42 | CD47 | CD47 Entrez, Source | CD47 molecule | 12700 | -0.205 | -0.4474 | Yes |
| 43 | DSTN | DSTN Entrez, Source | destrin (actin depolymerizing factor) | 12715 | -0.208 | -0.4110 | Yes |
| 44 | CREB3 | CREB3 Entrez, Source | cAMP responsive element binding protein 3 | 12781 | -0.218 | -0.3765 | Yes |
| 45 | TLE4 | TLE4 Entrez, Source | transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) | 12889 | -0.247 | -0.3401 | Yes |
| 46 | PRKAR1B | PRKAR1B Entrez, Source | protein kinase, cAMP-dependent, regulatory, type I, beta | 12903 | -0.254 | -0.2954 | Yes |
| 47 | TSC22D1 | TSC22D1 Entrez, Source | TSC22 domain family, member 1 | 13081 | -0.341 | -0.2474 | Yes |
| 48 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 13204 | -0.471 | -0.1718 | Yes |
| 49 | MME | MME Entrez, Source | membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase) | 13226 | -0.505 | -0.0824 | Yes |
| 50 | VIM | VIM Entrez, Source | vimentin | 13227 | -0.506 | 0.0087 | Yes |
