Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_72h_versus_single_gel_72h.class.cls
#double_gel_72h_versus_single_gel_72h_repos
Phenotypeclass.cls#double_gel_72h_versus_single_gel_72h_repos
Upregulated in classdouble_gel_72h
GeneSetFLECHNER_KIDNEY_TRANSPLANT_REJECTION_DN
Enrichment Score (ES)0.40376496
Normalized Enrichment Score (NES)1.7869449
Nominal p-value0.0
FDR q-value0.017871423
FWER p-Value0.923
Table: GSEA Results Summary



Fig 1: Enrichment plot: FLECHNER_KIDNEY_TRANSPLANT_REJECTION_DN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1FABP1FABP1
Entrez,  Source
fatty acid binding protein 1, liver21.1120.0234Yes
2EHHADHEHHADH
Entrez,  Source
enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase60.9080.0424Yes
3BBOX1BBOX1
Entrez,  Source
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1130.7400.0577Yes
4CYP17A1CYP17A1
Entrez,  Source
cytochrome P450, family 17, subfamily A, polypeptide 1140.7330.0732Yes
5ABP1ABP1
Entrez,  Source
amiloride binding protein 1 (amine oxidase (copper-containing))240.5940.0851Yes
6AFMAFM
Entrez,  Source
afamin280.5670.0969Yes
7GLYATGLYAT
Entrez,  Source
glycine-N-acyltransferase330.5540.1083Yes
8USP2USP2
Entrez,  Source
ubiquitin specific peptidase 2370.5350.1194Yes
9GSTA2GSTA2
Entrez,  Source
glutathione S-transferase A2390.5270.1305Yes
10FBP1FBP1
Entrez,  Source
fructose-1,6-bisphosphatase 1430.5150.1412Yes
11PLGPLG
Entrez,  Source
plasminogen810.4340.1475Yes
12DPYSDPYS
Entrez,  Source
dihydropyrimidinase900.4250.1559Yes
13KHKKHK
Entrez,  Source
ketohexokinase (fructokinase)930.4220.1647Yes
14BHMTBHMT
Entrez,  Source
betaine-homocysteine methyltransferase1060.4150.1726Yes
15GOT1GOT1
Entrez,  Source
glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)1100.4030.1809Yes
16APOMAPOM
Entrez,  Source
apolipoprotein M1130.4010.1892Yes
17G6PCG6PC
Entrez,  Source
glucose-6-phosphatase, catalytic subunit1290.3830.1962Yes
18ACAA2ACAA2
Entrez,  Source
acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase)1350.3740.2038Yes
19ENPP2ENPP2
Entrez,  Source
ectonucleotide pyrophosphatase/phosphodiesterase 2 (autotaxin)1430.3630.2109Yes
20SULT1C1SULT1C1
Entrez,  Source
sulfotransferase family, cytosolic, 1C, member 11480.3560.2182Yes
21PCPC
Entrez,  Source
pyruvate carboxylase1550.3470.2251Yes
22PRODH2PRODH2
Entrez,  Source
proline dehydrogenase (oxidase) 21690.3380.2312Yes
23ABATABAT
Entrez,  Source
4-aminobutyrate aminotransferase1850.3210.2369Yes
24SLC13A3SLC13A3
Entrez,  Source
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 31900.3180.2433Yes
25SLC37A4SLC37A4
Entrez,  Source
solute carrier family 37 (glycerol-6-phosphate transporter), member 42110.3050.2482Yes
26FAHFAH
Entrez,  Source
fumarylacetoacetate hydrolase (fumarylacetoacetase)2190.2990.2540Yes
27RBP4RBP4
Entrez,  Source
retinol binding protein 4, plasma2290.2940.2596Yes
28HPNHPN
Entrez,  Source
hepsin (transmembrane protease, serine 1)2540.2860.2638Yes
29AKR7A2AKR7A2
Entrez,  Source
aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)2600.2830.2694Yes
30ACOX1ACOX1
Entrez,  Source
acyl-Coenzyme A oxidase 1, palmitoyl2660.2810.2750Yes
31EPHX2EPHX2
Entrez,  Source
epoxide hydrolase 2, cytoplasmic2820.2740.2796Yes
32CATCAT
Entrez,  Source
catalase2900.2690.2848Yes
33AZGP1AZGP1
Entrez,  Source
alpha-2-glycoprotein 1, zinc2930.2680.2903Yes
34SERPINA5SERPINA5
Entrez,  Source
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 53050.2650.2951Yes
35SLC7A7SLC7A7
Entrez,  Source
solute carrier family 7 (cationic amino acid transporter, y+ system), member 73200.2600.2995Yes
36SLC17A1SLC17A1
Entrez,  Source
solute carrier family 17 (sodium phosphate), member 13590.2450.3018Yes
37TSTTST
Entrez,  Source
thiosulfate sulfurtransferase (rhodanese)3880.2350.3046Yes
38IGFBP4IGFBP4
Entrez,  Source
insulin-like growth factor binding protein 43910.2350.3094Yes
39SEPHS2SEPHS2
Entrez,  Source
selenophosphate synthetase 24040.2300.3134Yes
40MSH3MSH3
Entrez,  Source
mutS homolog 3 (E. coli)4200.2240.3170Yes
41NAT8NAT8
Entrez,  Source
N-acetyltransferase 8 (camello like)4310.2210.3209Yes
42FBXO9FBXO9
Entrez,  Source
F-box protein 94360.2200.3252Yes
43AK3L1AK3L1
Entrez,  Source
adenylate kinase 3-like 14420.2180.3295Yes
44SC4MOLSC4MOL
Entrez,  Source
sterol-C4-methyl oxidase-like4440.2180.3340Yes
45ALDH6A1ALDH6A1
Entrez,  Source
aldehyde dehydrogenase 6 family, member A14450.2170.3386Yes
46CTHCTH
Entrez,  Source
cystathionase (cystathionine gamma-lyase)4470.2160.3431Yes
47IGFBP2IGFBP2
Entrez,  Source
insulin-like growth factor binding protein 2, 36kDa4730.2090.3456Yes
48SC5DLSC5DL
Entrez,  Source
sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, fungal)-like5120.2010.3469Yes
49HRSP12HRSP12
Entrez,  Source
heat-responsive protein 125190.1980.3507Yes
50PTPN3PTPN3
Entrez,  Source
protein tyrosine phosphatase, non-receptor type 35510.1920.3524Yes
51GCHFRGCHFR
Entrez,  Source
GTP cyclohydrolase I feedback regulator5580.1910.3560Yes
52ACAT1ACAT1
Entrez,  Source
acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase)5600.1910.3599Yes
53ERBB3ERBB3
Entrez,  Source
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)5880.1870.3618Yes
54ALDH5A1ALDH5A1
Entrez,  Source
aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase)6120.1840.3639Yes
55PAHPAH
Entrez,  Source
phenylalanine hydroxylase6280.1820.3667Yes
56ECHS1ECHS1
Entrez,  Source
enoyl Coenzyme A hydratase, short chain, 1, mitochondrial6330.1820.3702Yes
57BCKDHBBCKDHB
Entrez,  Source
branched chain keto acid dehydrogenase E1, beta polypeptide (maple syrup urine disease)6510.1790.3727Yes
58NQO2NQO2
Entrez,  Source
NAD(P)H dehydrogenase, quinone 26580.1790.3760Yes
59APOHAPOH
Entrez,  Source
apolipoprotein H (beta-2-glycoprotein I)7260.1700.3745Yes
60HMGCLHMGCL
Entrez,  Source
3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (hydroxymethylglutaricaciduria)7320.1690.3776Yes
61AHCYAHCY
Entrez,  Source
S-adenosylhomocysteine hydrolase7980.1630.3761Yes
62HAGHHAGH
Entrez,  Source
hydroxyacylglutathione hydrolase8190.1610.3780Yes
63LRPPRCLRPPRC
Entrez,  Source
leucine-rich PPR-motif containing8380.1590.3799Yes
64AKR7A3AKR7A3
Entrez,  Source
aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)8450.1580.3828Yes
65SLC34A1SLC34A1
Entrez,  Source
solute carrier family 34 (sodium phosphate), member 18810.1550.3834Yes
66OATOAT
Entrez,  Source
ornithine aminotransferase (gyrate atrophy)8930.1540.3858Yes
67VEGFVEGF
Entrez,  Source
vascular endothelial growth factor9010.1530.3885Yes
68CYP4F2CYP4F2
Entrez,  Source
cytochrome P450, family 4, subfamily F, polypeptide 29330.1500.3893Yes
69SHMT1SHMT1
Entrez,  Source
serine hydroxymethyltransferase 1 (soluble)9390.1500.3921Yes
70UGDHUGDH
Entrez,  Source
UDP-glucose dehydrogenase9510.1490.3944Yes
71ALDOBALDOB
Entrez,  Source
aldolase B, fructose-bisphosphate10070.1440.3932Yes
72HBLD2HBLD2
Entrez,  Source
HESB like domain containing 210360.1410.3941Yes
73GPR116GPR116
Entrez,  Source
G protein-coupled receptor 11610630.1390.3950Yes
74DDTDDT
Entrez,  Source
D-dopachrome tautomerase10760.1390.3970Yes
75ACSM3ACSM3
Entrez,  Source
acyl-CoA synthetase medium-chain family member 310820.1380.3996Yes
76CRYMCRYM
Entrez,  Source
crystallin, mu11570.1330.3967Yes
77SLC31A1SLC31A1
Entrez,  Source
solute carrier family 31 (copper transporters), member 111730.1320.3983Yes
78MDH1MDH1
Entrez,  Source
malate dehydrogenase 1, NAD (soluble)12460.1270.3955Yes
79COMTCOMT
Entrez,  Source
catechol-O-methyltransferase12670.1260.3966Yes
80SLC17A3SLC17A3
Entrez,  Source
solute carrier family 17 (sodium phosphate), member 312790.1250.3984Yes
81GJB1GJB1
Entrez,  Source
gap junction protein, beta 1, 32kDa (connexin 32, Charcot-Marie-Tooth neuropathy, X-linked)12930.1240.4000Yes
82ACY1ACY1
Entrez,  Source
aminoacylase 113350.1220.3995Yes
83TACSTD1TACSTD1
Entrez,  Source
tumor-associated calcium signal transducer 113500.1210.4010Yes
84ATP5OATP5O
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein)13600.1210.4028Yes
85ASS1ASS1
Entrez,  Source
argininosuccinate synthetase 113820.1200.4038Yes
86ACADSBACADSB
Entrez,  Source
acyl-Coenzyme A dehydrogenase, short/branched chain14800.1140.3987No
87IDH1IDH1
Entrez,  Source
isocitrate dehydrogenase 1 (NADP+), soluble14940.1140.4001No
88QDPRQDPR
Entrez,  Source
quinoid dihydropteridine reductase15600.1100.3975No
89GPSN2GPSN2
Entrez,  Source
glycoprotein, synaptic 215670.1100.3993No
90MFAP3LMFAP3L
Entrez,  Source
microfibrillar-associated protein 3-like16130.1080.3982No
91HADHHADH
Entrez,  Source
hydroxyacyl-Coenzyme A dehydrogenase16220.1080.3998No
92SCP2SCP2
Entrez,  Source
sterol carrier protein 216320.1070.4014No
93TSPYL4TSPYL4
Entrez,  Source
TSPY-like 416910.1050.3992No
94RAB7L1RAB7L1
Entrez,  Source
RAB7, member RAS oncogene family-like 117190.1040.3993No
95ASPAASPA
Entrez,  Source
aspartoacylase (Canavan disease)17330.1040.4005No
96MAOBMAOB
Entrez,  Source
monoamine oxidase B17790.1020.3992No
97RABGGTBRABGGTB
Entrez,  Source
Rab geranylgeranyltransferase, beta subunit17940.1010.4003No
98NDUFS1NDUFS1
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)18170.1010.4007No
99GULP1GULP1
Entrez,  Source
GULP, engulfment adaptor PTB domain containing 118620.0990.3994No
100PCBD1PCBD1
Entrez,  Source
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1)18700.0990.4010No
101PEX19PEX19
Entrez,  Source
peroxisomal biogenesis factor 1918780.0980.4025No
102ANK3ANK3
Entrez,  Source
ankyrin 3, node of Ranvier (ankyrin G)19230.0970.4012No
103NEK4NEK4
Entrez,  Source
NIMA (never in mitosis gene a)-related kinase 420230.0930.3955No
104PHYHPHYH
Entrez,  Source
phytanoyl-CoA 2-hydroxylase20360.0930.3966No
105ADH6ADH6
Entrez,  Source
alcohol dehydrogenase 6 (class V)20530.0920.3973No
106PGM1PGM1
Entrez,  Source
phosphoglucomutase 120630.0920.3985No
107PTGER3PTGER3
Entrez,  Source
prostaglandin E receptor 3 (subtype EP3)20930.0910.3982No
108MRPS18BMRPS18B
Entrez,  Source
mitochondrial ribosomal protein S18B21180.0900.3983No
109COX7BCOX7B
Entrez,  Source
cytochrome c oxidase subunit VIIb21570.0890.3973No
110CYB5ACYB5A
Entrez,  Source
cytochrome b5 type A (microsomal)21790.0890.3975No
111ACO1ACO1
Entrez,  Source
aconitase 1, soluble22590.0860.3933No
112TOMM70ATOMM70A
Entrez,  Source
translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)22680.0860.3945No
113EBNA1BP2EBNA1BP2
Entrez,  Source
EBNA1 binding protein 222760.0860.3958No
114ENTPD5ENTPD5
Entrez,  Source
ectonucleoside triphosphate diphosphohydrolase 523000.0850.3958No
115WWP1WWP1
Entrez,  Source
WW domain containing E3 ubiquitin protein ligase 123060.0850.3972No
116CLDN8CLDN8
Entrez,  Source
claudin 823740.0830.3938No
117HIBCHHIBCH
Entrez,  Source
3-hydroxyisobutyryl-Coenzyme A hydrolase23920.0830.3942No
118PGRMC2PGRMC2
Entrez,  Source
progesterone receptor membrane component 224340.0820.3928No
119PDZK1PDZK1
Entrez,  Source
PDZ domain containing 124700.0810.3918No
120PHKBPHKB
Entrez,  Source
phosphorylase kinase, beta25150.0790.3901No
121PDE8APDE8A
Entrez,  Source
phosphodiesterase 8A25160.0790.3918No
122ACPPACPP
Entrez,  Source
acid phosphatase, prostate25460.0780.3912No
123DPP4DPP4
Entrez,  Source
dipeptidyl-peptidase 4 (CD26, adenosine deaminase complexing protein 2)26110.0760.3879No
124APLP2APLP2
Entrez,  Source
amyloid beta (A4) precursor-like protein 227110.0730.3818No
125BPHLBPHL
Entrez,  Source
biphenyl hydrolase-like (serine hydrolase; breast epithelial mucin-associated antigen)27200.0730.3828No
126CDS1CDS1
Entrez,  Source
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 127330.0730.3834No
127SDHASDHA
Entrez,  Source
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)27800.0720.3814No
128PDCD8PDCD8
Entrez,  Source
programmed cell death 8 (apoptosis-inducing factor)28030.0710.3812No
129SLC22A2SLC22A2
Entrez,  Source
solute carrier family 22 (organic cation transporter), member 228160.0710.3818No
130CLINT1CLINT1
Entrez,  Source
clathrin interactor 128390.0700.3816No
131ANKRD15ANKRD15
Entrez,  Source
ankyrin repeat domain 1528940.0690.3789No
132SLC25A1SLC25A1
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 129120.0690.3790No
133RRAGARRAGA
Entrez,  Source
Ras-related GTP binding A29430.0680.3782No
134HSPE1HSPE1
Entrez,  Source
heat shock 10kDa protein 1 (chaperonin 10)30200.0660.3737No
135PEX7PEX7
Entrez,  Source
peroxisomal biogenesis factor 730290.0660.3745No
136DNAJB9DNAJB9
Entrez,  Source
DnaJ (Hsp40) homolog, subfamily B, member 930360.0660.3754No
137GPC3GPC3
Entrez,  Source
glypican 330830.0650.3733No
138ACO2ACO2
Entrez,  Source
aconitase 2, mitochondrial31360.0640.3706No
139DLDDLD
Entrez,  Source
dihydrolipoamide dehydrogenase31420.0630.3716No
140DNM1LDNM1L
Entrez,  Source
dynamin 1-like31840.0630.3697No
141UQCRC2UQCRC2
Entrez,  Source
ubiquinol-cytochrome c reductase core protein II31870.0630.3709No
142CRYZCRYZ
Entrez,  Source
crystallin, zeta (quinone reductase)31980.0620.3714No
143IGF1RIGF1R
Entrez,  Source
insulin-like growth factor 1 receptor32410.0610.3695No
144ABCD3ABCD3
Entrez,  Source
ATP-binding cassette, sub-family D (ALD), member 333140.0600.3652No
145SMAD5SMAD5
Entrez,  Source
SMAD, mothers against DPP homolog 5 (Drosophila)33300.0590.3653No
146FYNFYN
Entrez,  Source
FYN oncogene related to SRC, FGR, YES33740.0590.3633No
147RNF14RNF14
Entrez,  Source
ring finger protein 1433840.0580.3638No
148MAOAMAOA
Entrez,  Source
monoamine oxidase A34270.0570.3618No
149PEX11BPEX11B
Entrez,  Source
peroxisomal biogenesis factor 11B36300.0530.3474No
150ANPEPANPEP
Entrez,  Source
alanyl (membrane) aminopeptidase (aminopeptidase N, aminopeptidase M, microsomal aminopeptidase, CD13, p150)36310.0530.3485No
151AKAP11AKAP11
Entrez,  Source
A kinase (PRKA) anchor protein 1137000.0520.3444No
152CA4CA4
Entrez,  Source
carbonic anhydrase IV37160.0520.3443No
153FPGTFPGT
Entrez,  Source
fucose-1-phosphate guanylyltransferase38100.0500.3382No
154ATP5A1ATP5A1
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle38500.0490.3362No
155UQCRC1UQCRC1
Entrez,  Source
ubiquinol-cytochrome c reductase core protein I39030.0480.3332No
156SORDSORD
Entrez,  Source
sorbitol dehydrogenase39560.0470.3302No
157PRKCAPRKCA
Entrez,  Source
protein kinase C, alpha39990.0460.3280No
158PDZK1IP1PDZK1IP1
Entrez,  Source
PDZK1 interacting protein 140230.0460.3272No
159IGFBP5IGFBP5
Entrez,  Source
insulin-like growth factor binding protein 540570.0450.3256No
160UQCRFS1UQCRFS1
Entrez,  Source
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 140730.0450.3254No
161XPNPEP2XPNPEP2
Entrez,  Source
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound40930.0450.3249No
162DCIDCI
Entrez,  Source
dodecenoyl-Coenzyme A delta isomerase (3,2 trans-enoyl-Coenzyme A isomerase)41670.0430.3202No
163ATP5JATP5J
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F641940.0430.3191No
164KCNJ15KCNJ15
Entrez,  Source
potassium inwardly-rectifying channel, subfamily J, member 1542500.0420.3157No
165PRDX3PRDX3
Entrez,  Source
peroxiredoxin 342710.0420.3151No
166ACADMACADM
Entrez,  Source
acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain42990.0410.3139No
167SLC22A6SLC22A6
Entrez,  Source
solute carrier family 22 (organic anion transporter), member 643050.0410.3144No
168PHBPHB
Entrez,  Source
prohibitin43090.0410.3150No
169COL4A4COL4A4
Entrez,  Source
collagen, type IV, alpha 443580.0400.3122No
170COX6A1COX6A1
Entrez,  Source
cytochrome c oxidase subunit VIa polypeptide 143670.0400.3124No
171HPDHPD
Entrez,  Source
4-hydroxyphenylpyruvate dioxygenase43830.0400.3121No
172STCHSTCH
Entrez,  Source
stress 70 protein chaperone, microsome-associated, 60kDa44130.0390.3107No
173PRPSAP2PRPSAP2
Entrez,  Source
phosphoribosyl pyrophosphate synthetase-associated protein 245110.0380.3040No
174HSD11B2HSD11B2
Entrez,  Source
hydroxysteroid (11-beta) dehydrogenase 245420.0370.3025No
175PEX3PEX3
Entrez,  Source
peroxisomal biogenesis factor 345690.0370.3013No
176QPRTQPRT
Entrez,  Source
quinolinate phosphoribosyltransferase (nicotinate-nucleotide pyrophosphorylase (carboxylating))45880.0360.3006No
177PPM1BPPM1B
Entrez,  Source
protein phosphatase 1B (formerly 2C), magnesium-dependent, beta isoform46440.0350.2972No
178CBR4CBR4
Entrez,  Source
carbonyl reductase 446620.0350.2966No
179SLC26A4SLC26A4
Entrez,  Source
solute carrier family 26, member 446680.0350.2969No
180HADHBHADHB
Entrez,  Source
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit46750.0350.2972No
181LRPAP1LRPAP1
Entrez,  Source
low density lipoprotein receptor-related protein associated protein 147510.0330.2921No
182NDUFS4NDUFS4
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)47530.0330.2928No
183PIK3R1PIK3R1
Entrez,  Source
phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha)47600.0330.2930No
184CGRRF1CGRRF1
Entrez,  Source
cell growth regulator with ring finger domain 147820.0330.2921No
185HPGDHPGD
Entrez,  Source
hydroxyprostaglandin dehydrogenase 15-(NAD)48030.0320.2912No
186ALDH3A2ALDH3A2
Entrez,  Source
aldehyde dehydrogenase 3 family, member A248190.0320.2908No
187CD9CD9
Entrez,  Source
CD9 molecule48960.0310.2856No
188CAP2CAP2
Entrez,  Source
CAP, adenylate cyclase-associated protein, 2 (yeast)49200.0300.2844No
189COPS5COPS5
Entrez,  Source
COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)50280.0290.2768No
190CLTBCLTB
Entrez,  Source
clathrin, light chain (Lcb)50460.0280.2761No
191GHITMGHITM
Entrez,  Source
growth hormone inducible transmembrane protein50530.0280.2762No
192GBE1GBE1
Entrez,  Source
glucan (1,4-alpha-), branching enzyme 1 (glycogen branching enzyme, Andersen disease, glycogen storage disease type IV)51190.0270.2718No
193FMO1FMO1
Entrez,  Source
flavin containing monooxygenase 151370.0270.2711No
194C1QBPC1QBP
Entrez,  Source
complement component 1, q subcomponent binding protein51570.0270.2702No
195PEBP1PEBP1
Entrez,  Source
phosphatidylethanolamine binding protein 151900.0260.2683No
196CDH1CDH1
Entrez,  Source
cadherin 1, type 1, E-cadherin (epithelial)53150.0240.2593No
197ETFAETFA
Entrez,  Source
electron-transfer-flavoprotein, alpha polypeptide (glutaric aciduria II)53360.0240.2582No
198STRAPSTRAP
Entrez,  Source
serine/threonine kinase receptor associated protein53630.0240.2567No
199ADD3ADD3
Entrez,  Source
adducin 3 (gamma)54030.0230.2542No
200NARSNARS
Entrez,  Source
asparaginyl-tRNA synthetase54260.0230.2530No
201COPACOPA
Entrez,  Source
coatomer protein complex, subunit alpha54490.0220.2518No
202FOLH1FOLH1
Entrez,  Source
folate hydrolase (prostate-specific membrane antigen) 154810.0220.2499No
203IMMTIMMT
Entrez,  Source
inner membrane protein, mitochondrial (mitofilin)56520.0200.2372No
204SDHCSDHC
Entrez,  Source
succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa57890.0180.2271No
205ECH1ECH1
Entrez,  Source
enoyl Coenzyme A hydratase 1, peroxisomal58590.0160.2221No
206TEGTTEGT
Entrez,  Source
testis enhanced gene transcript (BAX inhibitor 1)58920.0160.2200No
207VDAC2VDAC2
Entrez,  Source
voltage-dependent anion channel 259870.0140.2130No
208PCK1PCK1
Entrez,  Source
phosphoenolpyruvate carboxykinase 1 (soluble)60260.0140.2104No
209OGG1OGG1
Entrez,  Source
8-oxoguanine DNA glycosylase61180.0130.2037No
210ALDH2ALDH2
Entrez,  Source
aldehyde dehydrogenase 2 family (mitochondrial)61750.0120.1996No
211TMED10TMED10
Entrez,  Source
transmembrane emp24-like trafficking protein 10 (yeast)61850.0120.1992No
212HSPD1HSPD1
Entrez,  Source
heat shock 60kDa protein 1 (chaperonin)62420.0110.1951No
213CRYAACRYAA
Entrez,  Source
crystallin, alpha A63790.0080.1848No
214DEFB1DEFB1
Entrez,  Source
defensin, beta 164680.0070.1781No
215TOB1TOB1
Entrez,  Source
transducer of ERBB2, 165670.0060.1707No
216SNRPN /// SNURF66490.0050.1646No
217CYCSCYCS
Entrez,  Source
cytochrome c, somatic67070.0040.1603No
218MYH11MYH11
Entrez,  Source
myosin, heavy chain 11, smooth muscle67210.0040.1593No
219SLC3A2SLC3A2
Entrez,  Source
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 268170.0020.1521No
220DDX3XDDX3X
Entrez,  Source
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked68180.0020.1521No
221NR3C2NR3C2
Entrez,  Source
nuclear receptor subfamily 3, group C, member 268570.0020.1492No
222CALB1CALB1
Entrez,  Source
calbindin 1, 28kDa68940.0010.1465No
223RFKRFK
Entrez,  Source
riboflavin kinase69010.0010.1460No
224ST13ST13
Entrez,  Source
suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)7031-0.0010.1361No
225TOMM20TOMM20
Entrez,  Source
translocase of outer mitochondrial membrane 20 homolog (yeast)7046-0.0010.1351No
226COPS2COPS2
Entrez,  Source
COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)7084-0.0020.1323No
227ALBALB
Entrez,  Source
albumin7095-0.0020.1315No
228AKR1A1AKR1A1
Entrez,  Source
aldo-keto reductase family 1, member A1 (aldehyde reductase)7127-0.0020.1292No
229RAB1ARAB1A
Entrez,  Source
RAB1A, member RAS oncogene family7133-0.0020.1288No
230PGK1PGK1
Entrez,  Source
phosphoglycerate kinase 17152-0.0020.1275No
231CA2CA2
Entrez,  Source
carbonic anhydrase II7159-0.0020.1271No
232VDAC1VDAC1
Entrez,  Source
voltage-dependent anion channel 17242-0.0040.1209No
233NDUFA5NDUFA5
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa7283-0.0040.1179No
234BAMBIBAMBI
Entrez,  Source
BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)7381-0.0060.1105No
235BEXL1BEXL1
Entrez,  Source
brain expressed X-linked-like 17432-0.0060.1068No
236ZNF148ZNF148
Entrez,  Source
zinc finger protein 1487480-0.0070.1033No
237ANKRD46ANKRD46
Entrez,  Source
ankyrin repeat domain 467606-0.0090.0939No
238PMPCBPMPCB
Entrez,  Source
peptidase (mitochondrial processing) beta7633-0.0100.0921No
239NR1D2NR1D2
Entrez,  Source
nuclear receptor subfamily 1, group D, member 27779-0.0120.0812No
240SERINC1SERINC1
Entrez,  Source
serine incorporator 17788-0.0120.0808No
241BNIP3BNIP3
Entrez,  Source
BCL2/adenovirus E1B 19kDa interacting protein 37875-0.0130.0745No
242SOD1SOD1
Entrez,  Source
superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult))7883-0.0130.0742No
243RAB2RAB2
Entrez,  Source
RAB2, member RAS oncogene family7949-0.0140.0695No
244CYB5R3CYB5R3
Entrez,  Source
cytochrome b5 reductase 38007-0.0150.0655No
245SERBP1SERBP1
Entrez,  Source
SERPINE1 mRNA binding protein 18112-0.0160.0578No
246YWHAEYWHAE
Entrez,  Source
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide8149-0.0170.0554No
247SCAMP1SCAMP1
Entrez,  Source
secretory carrier membrane protein 18178-0.0180.0536No
248LRP2LRP2
Entrez,  Source
low density lipoprotein-related protein 28183-0.0180.0537No
249ENPEPENPEP
Entrez,  Source
glutamyl aminopeptidase (aminopeptidase A)8208-0.0180.0522No
250SLC7A8SLC7A8
Entrez,  Source
solute carrier family 7 (cationic amino acid transporter, y+ system), member 88292-0.0200.0462No
251EFHA1EFHA1
Entrez,  Source
EF-hand domain family, member A18302-0.0200.0460No
252MINPP1MINPP1
Entrez,  Source
multiple inositol polyphosphate histidine phosphatase, 18313-0.0200.0456No
253PGRMC1PGRMC1
Entrez,  Source
progesterone receptor membrane component 18338-0.0200.0442No
254G3BPG3BP
Entrez,  Source
-8348-0.0210.0439No
255PARGPARG
Entrez,  Source
poly (ADP-ribose) glycohydrolase8393-0.0210.0410No
256DDCDDC
Entrez,  Source
dopa decarboxylase (aromatic L-amino acid decarboxylase)8401-0.0210.0409No
257SLC12A3SLC12A3
Entrez,  Source
solute carrier family 12 (sodium/chloride transporters), member 38709-0.0260.0178No
258ATF2ATF2
Entrez,  Source
activating transcription factor 29097-0.034-0.0112No
259PRDX2PRDX2
Entrez,  Source
peroxiredoxin 29109-0.034-0.0114No
260PAFAH1B1PAFAH1B1
Entrez,  Source
platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa9229-0.036-0.0198No
261CDC42BPACDC42BPA
Entrez,  Source
CDC42 binding protein kinase alpha (DMPK-like)9266-0.037-0.0217No
262PFN2PFN2
Entrez,  Source
profilin 29269-0.037-0.0211No
263CTSLCTSL
Entrez,  Source
cathepsin L9328-0.038-0.0248No
264AQP1AQP1
Entrez,  Source
aquaporin 1 (Colton blood group)9344-0.039-0.0251No
265CFDP1CFDP1
Entrez,  Source
craniofacial development protein 19346-0.039-0.0244No
266TMED5TMED5
Entrez,  Source
transmembrane emp24 protein transport domain containing 59395-0.040-0.0272No
267FMR1FMR1
Entrez,  Source
fragile X mental retardation 19448-0.041-0.0304No
268SLC1A1SLC1A1
Entrez,  Source
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 19452-0.041-0.0297No
269SERPINI1SERPINI1
Entrez,  Source
serpin peptidase inhibitor, clade I (neuroserpin), member 19454-0.041-0.0289No
270PJA2PJA2
Entrez,  Source
praja 2, RING-H2 motif containing9485-0.041-0.0304No
271ESRRGESRRG
Entrez,  Source
estrogen-related receptor gamma9512-0.042-0.0315No
272RDXRDX
Entrez,  Source
radixin9584-0.043-0.0360No
273MORF4L2MORF4L2
Entrez,  Source
mortality factor 4 like 29663-0.045-0.0411No
274ATP2A2ATP2A2
Entrez,  Source
ATPase, Ca++ transporting, cardiac muscle, slow twitch 29784-0.048-0.0493No
275PPP2R1APPP2R1A
Entrez,  Source
protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform9862-0.049-0.0542No
276HDGFHDGF
Entrez,  Source
hepatoma-derived growth factor (high-mobility group protein 1-like)9904-0.050-0.0563No
277MXI1MXI1
Entrez,  Source
MAX interactor 19949-0.051-0.0586No
278CDKN1CCDKN1C
Entrez,  Source
cyclin-dependent kinase inhibitor 1C (p57, Kip2)10008-0.052-0.0620No
279PCBP2PCBP2
Entrez,  Source
poly(rC) binding protein 210047-0.053-0.0638No
280SHANK2SHANK2
Entrez,  Source
SH3 and multiple ankyrin repeat domains 210101-0.054-0.0667No
281FGF9FGF9
Entrez,  Source
fibroblast growth factor 9 (glia-activating factor)10145-0.055-0.0689No
282AQP3AQP3
Entrez,  Source
aquaporin 3 (Gill blood group)10174-0.056-0.0698No
283FAM3CFAM3C
Entrez,  Source
family with sequence similarity 3, member C10235-0.058-0.0732No
284PRKAR1APRKAR1A
Entrez,  Source
protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)10251-0.058-0.0732No
285USP14USP14
Entrez,  Source
ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)10365-0.061-0.0806No
286PTHR1PTHR1
Entrez,  Source
parathyroid hormone receptor 110494-0.064-0.0891No
287ITM2BITM2B
Entrez,  Source
integral membrane protein 2B10579-0.066-0.0941No
288PARD3PARD3
Entrez,  Source
par-3 partitioning defective 3 homolog (C. elegans)10642-0.068-0.0975No
289UGT8UGT8
Entrez,  Source
UDP glycosyltransferase 8 (UDP-galactose ceramide galactosyltransferase)10649-0.068-0.0965No
290HSPA8HSPA8
Entrez,  Source
heat shock 70kDa protein 810653-0.068-0.0953No
291ALDH9A1ALDH9A1
Entrez,  Source
aldehyde dehydrogenase 9 family, member A110674-0.069-0.0954No
292RNASE4RNASE4
Entrez,  Source
ribonuclease, RNase A family, 410748-0.071-0.0995No
293CALM1CALM1
Entrez,  Source
calmodulin 1 (phosphorylase kinase, delta)10814-0.073-0.1029No
294CTBP1CTBP1
Entrez,  Source
C-terminal binding protein 110835-0.073-0.1029No
295AP3D1AP3D1
Entrez,  Source
adaptor-related protein complex 3, delta 1 subunit10841-0.074-0.1017No
296TNPO1TNPO1
Entrez,  Source
transportin 110873-0.074-0.1025No
297ZMYND11ZMYND11
Entrez,  Source
zinc finger, MYND domain containing 1110901-0.075-0.1030No
298CREB3L2CREB3L2
Entrez,  Source
cAMP responsive element binding protein 3-like 210974-0.078-0.1069No
299TNFRSF11BTNFRSF11B
Entrez,  Source
tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)11055-0.080-0.1114No
300NCKAP1NCKAP1
Entrez,  Source
NCK-associated protein 111089-0.082-0.1122No
301SMAD4SMAD4
Entrez,  Source
SMAD, mothers against DPP homolog 4 (Drosophila)11091-0.082-0.1105No
302PPP2CBPPP2CB
Entrez,  Source
protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform11093-0.082-0.1089No
303ANXA7ANXA7
Entrez,  Source
annexin A711132-0.083-0.1101No
304SELENBP1SELENBP1
Entrez,  Source
selenium binding protein 111162-0.084-0.1105No
305STRN3STRN3
Entrez,  Source
striatin, calmodulin binding protein 311294-0.090-0.1187No
306KLKL
Entrez,  Source
klotho11354-0.093-0.1213No
307SDC1SDC1
Entrez,  Source
syndecan 111411-0.095-0.1236No
308KIF3AKIF3A
Entrez,  Source
kinesin family member 3A11439-0.097-0.1236No
309GATMGATM
Entrez,  Source
glycine amidinotransferase (L-arginine:glycine amidinotransferase)11580-0.103-0.1322No
310DZIP1DZIP1
Entrez,  Source
DAZ interacting protein 111582-0.103-0.1301No
311KDRKDR
Entrez,  Source
kinase insert domain receptor (a type III receptor tyrosine kinase)11669-0.108-0.1344No
312DAPDAP
Entrez,  Source
death-associated protein11716-0.110-0.1356No
313HNMTHNMT
Entrez,  Source
histamine N-methyltransferase11747-0.111-0.1356No
314CLASP2CLASP2
Entrez,  Source
cytoplasmic linker associated protein 211749-0.111-0.1333No
315ABCC2ABCC2
Entrez,  Source
ATP-binding cassette, sub-family C (CFTR/MRP), member 212020-0.126-0.1514No
316DSCR1DSCR1
Entrez,  Source
Down syndrome critical region gene 112036-0.127-0.1499No
317IMPA2IMPA2
Entrez,  Source
inositol(myo)-1(or 4)-monophosphatase 212041-0.127-0.1475No
318HTRA1HTRA1
Entrez,  Source
HtrA serine peptidase 112167-0.136-0.1542No
319PTPRDPTPRD
Entrez,  Source
protein tyrosine phosphatase, receptor type, D12216-0.141-0.1549No
320SLC4A4SLC4A4
Entrez,  Source
solute carrier family 4, sodium bicarbonate cotransporter, member 412225-0.142-0.1525No
321LGALS2LGALS2
Entrez,  Source
lectin, galactoside-binding, soluble, 2 (galectin 2)12278-0.146-0.1534No
322PLS3PLS3
Entrez,  Source
plastin 3 (T isoform)12321-0.150-0.1535No
323RGNRGN
Entrez,  Source
regucalcin (senescence marker protein-30)12427-0.161-0.1582No
324GGHGGH
Entrez,  Source
gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)12437-0.162-0.1554No
325ARMCX2ARMCX2
Entrez,  Source
armadillo repeat containing, X-linked 212467-0.166-0.1541No
326SMPDL3ASMPDL3A
Entrez,  Source
sphingomyelin phosphodiesterase, acid-like 3A12490-0.169-0.1523No
327FGF1FGF1
Entrez,  Source
fibroblast growth factor 1 (acidic)12527-0.175-0.1513No
328CLIC4CLIC4
Entrez,  Source
chloride intracellular channel 412577-0.181-0.1513No
329TRIM2TRIM2
Entrez,  Source
tripartite motif-containing 212579-0.181-0.1475No
330GLSGLS
Entrez,  Source
glutaminase12588-0.183-0.1442No
331GRB14GRB14
Entrez,  Source
growth factor receptor-bound protein 1412643-0.193-0.1443No
332DSPDSP
Entrez,  Source
desmoplakin12648-0.194-0.1405No
333SLC25A4SLC25A4
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 412710-0.207-0.1408No
334DSTNDSTN
Entrez,  Source
destrin (actin depolymerizing factor)12715-0.208-0.1367No
335PRKCIPRKCI
Entrez,  Source
protein kinase C, iota12716-0.208-0.1323No
336MPDZMPDZ
Entrez,  Source
multiple PDZ domain protein12723-0.209-0.1283No
337PRKRAPRKRA
Entrez,  Source
protein kinase, interferon-inducible double stranded RNA dependent activator12753-0.214-0.1260No
338VAT1VAT1
Entrez,  Source
vesicle amine transport protein 1 homolog (T californica)12754-0.214-0.1215No
339HRASLS3HRASLS3
Entrez,  Source
HRAS-like suppressor 312789-0.221-0.1194No
340ABCC4ABCC4
Entrez,  Source
ATP-binding cassette, sub-family C (CFTR/MRP), member 412805-0.226-0.1158No
341MAFMAF
Entrez,  Source
v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)12812-0.228-0.1114No
342PODXLPODXL
Entrez,  Source
podocalyxin-like12834-0.233-0.1081No
343HSPB1HSPB1
Entrez,  Source
heat shock 27kDa protein 112847-0.236-0.1040No
344ITGA6ITGA6
Entrez,  Source
integrin, alpha 612855-0.239-0.0995No
345WEE1WEE1
Entrez,  Source
WEE1 homolog (S. pombe)12929-0.262-0.0996No
346MYH10MYH10
Entrez,  Source
myosin, heavy chain 10, non-muscle12969-0.279-0.0967No
347PRNPPRNP
Entrez,  Source
prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia)13038-0.313-0.0953No
348TSC22D1TSC22D1
Entrez,  Source
TSC22 domain family, member 113081-0.341-0.0913No
349GPX3GPX3
Entrez,  Source
glutathione peroxidase 3 (plasma)13095-0.352-0.0848No
350HSPA4HSPA4
Entrez,  Source
heat shock 70kDa protein 413114-0.366-0.0785No
351DAB2DAB2
Entrez,  Source
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)13152-0.403-0.0728No
352CRYABCRYAB
Entrez,  Source
crystallin, alpha B13153-0.404-0.0642No
353RTN4RTN4
Entrez,  Source
reticulon 413219-0.495-0.0587No
354MMEMME
Entrez,  Source
membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase)13226-0.505-0.0485No
355PDLIM5PDLIM5
Entrez,  Source
PDZ and LIM domain 513261-0.575-0.0389No
356NDRG1NDRG1
Entrez,  Source
N-myc downstream regulated gene 113266-0.607-0.0264No
357F2RF2R
Entrez,  Source
coagulation factor II (thrombin) receptor13282-0.665-0.0134No
358PPP2R3APPP2R3A
Entrez,  Source
protein phosphatase 2 (formerly 2A), regulatory subunit B'', alpha13312-0.8470.0023No
Table: GSEA details [plain text format]



Fig 2: FLECHNER_KIDNEY_TRANSPLANT_REJECTION_DN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: FLECHNER_KIDNEY_TRANSPLANT_REJECTION_DN: Random ES distribution   
Gene set null distribution of ES for FLECHNER_KIDNEY_TRANSPLANT_REJECTION_DN