Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | FRASOR_ER_DN |
| Enrichment Score (ES) | -0.627567 |
| Normalized Enrichment Score (NES) | -1.9056325 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.01943261 |
| FWER p-Value | 0.553 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PPP1R3C | PPP1R3C Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 3C | 71 | 0.452 | 0.0490 | No |
| 2 | GNE | GNE Entrez, Source | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase | 599 | 0.186 | 0.0318 | No |
| 3 | KYNU | KYNU Entrez, Source | kynureninase (L-kynurenine hydrolase) | 695 | 0.174 | 0.0455 | No |
| 4 | BMP4 | BMP4 Entrez, Source | bone morphogenetic protein 4 | 1526 | 0.112 | -0.0035 | No |
| 5 | MB | MB Entrez, Source | myoglobin | 1607 | 0.109 | 0.0036 | No |
| 6 | PVALB | PVALB Entrez, Source | parvalbumin | 3324 | 0.059 | -0.1184 | No |
| 7 | EFNA1 | EFNA1 Entrez, Source | ephrin-A1 | 3378 | 0.058 | -0.1153 | No |
| 8 | SLIT2 | SLIT2 Entrez, Source | slit homolog 2 (Drosophila) | 3770 | 0.050 | -0.1387 | No |
| 9 | ENC1 | ENC1 Entrez, Source | ectodermal-neural cortex (with BTB-like domain) | 3917 | 0.048 | -0.1439 | No |
| 10 | DUSP4 | DUSP4 Entrez, Source | dual specificity phosphatase 4 | 4576 | 0.037 | -0.1890 | No |
| 11 | FOLH1 | FOLH1 Entrez, Source | folate hydrolase (prostate-specific membrane antigen) 1 | 5481 | 0.022 | -0.2543 | No |
| 12 | ECH1 | ECH1 Entrez, Source | enoyl Coenzyme A hydratase 1, peroxisomal | 5859 | 0.016 | -0.2807 | No |
| 13 | IFI30 | IFI30 Entrez, Source | interferon, gamma-inducible protein 30 | 5860 | 0.016 | -0.2787 | No |
| 14 | ARNT2 | ARNT2 Entrez, Source | aryl-hydrocarbon receptor nuclear translocator 2 | 5871 | 0.016 | -0.2775 | No |
| 15 | PIB5PA | PIB5PA Entrez, Source | phosphatidylinositol (4,5) bisphosphate 5-phosphatase, A | 6537 | 0.006 | -0.3268 | No |
| 16 | EPOR | EPOR Entrez, Source | erythropoietin receptor | 6541 | 0.006 | -0.3264 | No |
| 17 | DUSP1 | DUSP1 Entrez, Source | dual specificity phosphatase 1 | 6673 | 0.004 | -0.3357 | No |
| 18 | PRPS1 | PRPS1 Entrez, Source | phosphoribosyl pyrophosphate synthetase 1 | 6821 | 0.002 | -0.3465 | No |
| 19 | FMO5 | FMO5 Entrez, Source | flavin containing monooxygenase 5 | 7369 | -0.006 | -0.3869 | No |
| 20 | STXBP1 | STXBP1 Entrez, Source | syntaxin binding protein 1 | 7484 | -0.007 | -0.3946 | No |
| 21 | MYO1B | MYO1B Entrez, Source | myosin IB | 8141 | -0.017 | -0.4419 | No |
| 22 | NELL2 | NELL2 Entrez, Source | NEL-like 2 (chicken) | 8206 | -0.018 | -0.4446 | No |
| 23 | IL1R1 | IL1R1 Entrez, Source | interleukin 1 receptor, type I | 8618 | -0.025 | -0.4725 | No |
| 24 | IER3 | IER3 Entrez, Source | immediate early response 3 | 9311 | -0.038 | -0.5200 | No |
| 25 | CTSL | CTSL Entrez, Source | cathepsin L | 9328 | -0.038 | -0.5166 | No |
| 26 | GNS | GNS Entrez, Source | glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID) | 9802 | -0.048 | -0.5464 | No |
| 27 | L1CAM | L1CAM Entrez, Source | L1 cell adhesion molecule | 10517 | -0.065 | -0.5923 | No |
| 28 | BCAS1 | BCAS1 Entrez, Source | breast carcinoma amplified sequence 1 | 10524 | -0.065 | -0.5850 | No |
| 29 | CTSH | CTSH Entrez, Source | cathepsin H | 10687 | -0.069 | -0.5888 | No |
| 30 | LITAF | LITAF Entrez, Source | lipopolysaccharide-induced TNF factor | 10871 | -0.074 | -0.5936 | No |
| 31 | TRG@ | TRG@ Entrez, Source | T cell receptor gamma locus | 10920 | -0.076 | -0.5881 | No |
| 32 | SELENBP1 | SELENBP1 Entrez, Source | selenium binding protein 1 | 11162 | -0.084 | -0.5962 | No |
| 33 | BLNK | BLNK Entrez, Source | B-cell linker | 11422 | -0.096 | -0.6041 | No |
| 34 | ABCC5 | ABCC5 Entrez, Source | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 11735 | -0.111 | -0.6143 | Yes |
| 35 | STC1 | STC1 Entrez, Source | stanniocalcin 1 | 11795 | -0.113 | -0.6051 | Yes |
| 36 | CLU | CLU Entrez, Source | clusterin | 12046 | -0.128 | -0.6085 | Yes |
| 37 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 12112 | -0.132 | -0.5975 | Yes |
| 38 | ERBB2 | ERBB2 Entrez, Source | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 12233 | -0.142 | -0.5895 | Yes |
| 39 | CBX6 | CBX6 Entrez, Source | chromobox homolog 6 | 12602 | -0.184 | -0.5950 | Yes |
| 40 | BIK | BIK Entrez, Source | BCL2-interacting killer (apoptosis-inducing) | 12782 | -0.219 | -0.5822 | Yes |
| 41 | ANXA3 | ANXA3 Entrez, Source | annexin A3 | 13069 | -0.331 | -0.5639 | Yes |
| 42 | ABCG1 | ABCG1 Entrez, Source | ATP-binding cassette, sub-family G (WHITE), member 1 | 13162 | -0.417 | -0.5207 | Yes |
| 43 | TGFB3 | TGFB3 Entrez, Source | transforming growth factor, beta 3 | 13210 | -0.480 | -0.4665 | Yes |
| 44 | NDRG1 | NDRG1 Entrez, Source | N-myc downstream regulated gene 1 | 13266 | -0.607 | -0.3977 | Yes |
| 45 | LAMB2 | LAMB2 Entrez, Source | laminin, beta 2 (laminin S) | 13299 | -0.740 | -0.3111 | Yes |
| 46 | DBN1 | DBN1 Entrez, Source | drebrin 1 | 13318 | -0.939 | -0.1996 | Yes |
| 47 | CD24 | CD24 Entrez, Source | CD24 molecule | 13341 | -1.675 | 0.0001 | Yes |
