Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | FSH_OVARY_MCV152_UP |
| Enrichment Score (ES) | 0.57533234 |
| Normalized Enrichment Score (NES) | 1.8071731 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.014327531 |
| FWER p-Value | 0.861 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | TM7SF2 | TM7SF2 Entrez, Source | transmembrane 7 superfamily member 2 | 60 | 0.482 | 0.0855 | Yes |
| 2 | FASN | FASN Entrez, Source | fatty acid synthase | 101 | 0.417 | 0.1605 | Yes |
| 3 | IDI1 | IDI1 Entrez, Source | isopentenyl-diphosphate delta isomerase 1 | 136 | 0.372 | 0.2276 | Yes |
| 4 | FDFT1 | FDFT1 Entrez, Source | farnesyl-diphosphate farnesyltransferase 1 | 158 | 0.346 | 0.2906 | Yes |
| 5 | MVD | MVD Entrez, Source | mevalonate (diphospho) decarboxylase | 174 | 0.334 | 0.3518 | Yes |
| 6 | FADS2 | FADS2 Entrez, Source | fatty acid desaturase 2 | 182 | 0.324 | 0.4119 | Yes |
| 7 | SQLE | SQLE Entrez, Source | squalene epoxidase | 287 | 0.271 | 0.4549 | Yes |
| 8 | HMGCR | HMGCR Entrez, Source | 3-hydroxy-3-methylglutaryl-Coenzyme A reductase | 328 | 0.257 | 0.5000 | Yes |
| 9 | CYP51A1 | CYP51A1 Entrez, Source | cytochrome P450, family 51, subfamily A, polypeptide 1 | 366 | 0.244 | 0.5428 | Yes |
| 10 | FDPS | FDPS Entrez, Source | farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase) | 462 | 0.212 | 0.5753 | Yes |
| 11 | PIR | PIR Entrez, Source | pirin (iron-binding nuclear protein) | 1308 | 0.124 | 0.5349 | No |
| 12 | RBP1 | RBP1 Entrez, Source | retinol binding protein 1, cellular | 1390 | 0.119 | 0.5511 | No |
| 13 | FADS1 | FADS1 Entrez, Source | fatty acid desaturase 1 | 1495 | 0.114 | 0.5645 | No |
| 14 | ANK3 | ANK3 Entrez, Source | ankyrin 3, node of Ranvier (ankyrin G) | 1923 | 0.097 | 0.5505 | No |
| 15 | HIST2H2AA3 | HIST2H2AA3 Entrez, Source | histone cluster 2, H2aa3 | 2660 | 0.075 | 0.5092 | No |
| 16 | COL16A1 | COL16A1 Entrez, Source | collagen, type XVI, alpha 1 | 3121 | 0.064 | 0.4865 | No |
| 17 | GOSR1 | GOSR1 Entrez, Source | golgi SNAP receptor complex member 1 | 3296 | 0.060 | 0.4847 | No |
| 18 | CASP1 | CASP1 Entrez, Source | caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) | 4076 | 0.045 | 0.4345 | No |
| 19 | ATP5I | ATP5I Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit E | 4269 | 0.042 | 0.4279 | No |
| 20 | NAB1 | NAB1 Entrez, Source | NGFI-A binding protein 1 (EGR1 binding protein 1) | 4286 | 0.041 | 0.4345 | No |
| 21 | HNRPDL | HNRPDL Entrez, Source | heterogeneous nuclear ribonucleoprotein D-like | 4822 | 0.032 | 0.4003 | No |
| 22 | SPOP | SPOP Entrez, Source | speckle-type POZ protein | 6006 | 0.014 | 0.3140 | No |
| 23 | PSMB4 | PSMB4 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 4 | 7246 | -0.004 | 0.2215 | No |
| 24 | EEF1A1 | EEF1A1 Entrez, Source | eukaryotic translation elongation factor 1 alpha 1 | 7318 | -0.005 | 0.2171 | No |
| 25 | ZNF148 | ZNF148 Entrez, Source | zinc finger protein 148 | 7480 | -0.007 | 0.2063 | No |
| 26 | CTNNB1 | CTNNB1 Entrez, Source | catenin (cadherin-associated protein), beta 1, 88kDa | 8312 | -0.020 | 0.1476 | No |
| 27 | AXL | AXL Entrez, Source | AXL receptor tyrosine kinase | 8404 | -0.021 | 0.1448 | No |
| 28 | SLC4A3 | SLC4A3 Entrez, Source | solute carrier family 4, anion exchanger, member 3 | 9406 | -0.040 | 0.0770 | No |
| 29 | PDCD4 | PDCD4 Entrez, Source | programmed cell death 4 (neoplastic transformation inhibitor) | 10099 | -0.054 | 0.0351 | No |
| 30 | FCGRT | FCGRT Entrez, Source | Fc fragment of IgG, receptor, transporter, alpha | 10155 | -0.056 | 0.0414 | No |
| 31 | BFSP1 | BFSP1 Entrez, Source | beaded filament structural protein 1, filensin | 10212 | -0.057 | 0.0478 | No |
| 32 | TNPO1 | TNPO1 Entrez, Source | transportin 1 | 10873 | -0.074 | 0.0122 | No |
| 33 | CASP6 | CASP6 Entrez, Source | caspase 6, apoptosis-related cysteine peptidase | 11468 | -0.098 | -0.0141 | No |
| 34 | PSMB9 | PSMB9 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) | 11801 | -0.114 | -0.0178 | No |
| 35 | CLU | CLU Entrez, Source | clusterin | 12046 | -0.128 | -0.0122 | No |
| 36 | COL3A1 | COL3A1 Entrez, Source | collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) | 12541 | -0.177 | -0.0162 | No |
| 37 | DPYSL3 | DPYSL3 Entrez, Source | dihydropyrimidinase-like 3 | 13155 | -0.408 | 0.0141 | No |
