Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | GLUCOSE_METABOLIC_PROCESS |
| Enrichment Score (ES) | 0.65949607 |
| Normalized Enrichment Score (NES) | 1.7537652 |
| Nominal p-value | 0.006198347 |
| FDR q-value | 0.022928298 |
| FWER p-Value | 0.979 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GCK | GCK Entrez, Source | glucokinase (hexokinase 4, maturity onset diabetes of the young 2) | 140 | 0.368 | 0.1339 | Yes |
| 2 | PFKFB1 | PFKFB1 Entrez, Source | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 | 230 | 0.293 | 0.2424 | Yes |
| 3 | ACN9 | ACN9 Entrez, Source | ACN9 homolog (S. cerevisiae) | 284 | 0.273 | 0.3457 | Yes |
| 4 | SLC25A10 | SLC25A10 Entrez, Source | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 | 378 | 0.240 | 0.4329 | Yes |
| 5 | PDK4 | PDK4 Entrez, Source | pyruvate dehydrogenase kinase, isozyme 4 | 412 | 0.227 | 0.5197 | Yes |
| 6 | PDK1 | PDK1 Entrez, Source | pyruvate dehydrogenase kinase, isozyme 1 | 673 | 0.176 | 0.5694 | Yes |
| 7 | UGDH | UGDH Entrez, Source | UDP-glucose dehydrogenase | 951 | 0.149 | 0.6071 | Yes |
| 8 | ALDOB | ALDOB Entrez, Source | aldolase B, fructose-bisphosphate | 1007 | 0.144 | 0.6595 | Yes |
| 9 | PDK2 | PDK2 Entrez, Source | pyruvate dehydrogenase kinase, isozyme 2 | 2834 | 0.071 | 0.5502 | No |
| 10 | ATF4 | ATF4 Entrez, Source | activating transcription factor 4 (tax-responsive enhancer element B67) | 3058 | 0.065 | 0.5590 | No |
| 11 | ARPP-19 | ARPP-19 Entrez, Source | - | 5020 | 0.029 | 0.4231 | No |
| 12 | UGP2 | UGP2 Entrez, Source | UDP-glucose pyrophosphorylase 2 | 5626 | 0.020 | 0.3856 | No |
| 13 | GAPDHS | GAPDHS Entrez, Source | glyceraldehyde-3-phosphate dehydrogenase, spermatogenic | 6929 | 0.001 | 0.2881 | No |
| 14 | AKR1A1 | AKR1A1 Entrez, Source | aldo-keto reductase family 1, member A1 (aldehyde reductase) | 7127 | -0.002 | 0.2741 | No |
| 15 | PPARGC1A | PPARGC1A Entrez, Source | peroxisome proliferative activated receptor, gamma, coactivator 1, alpha | 8036 | -0.015 | 0.2120 | No |
| 16 | ALDOA | ALDOA Entrez, Source | aldolase A, fructose-bisphosphate | 9779 | -0.047 | 0.0999 | No |
| 17 | PFKL | PFKL Entrez, Source | phosphofructokinase, liver | 10756 | -0.071 | 0.0547 | No |
| 18 | HK1 | HK1 Entrez, Source | hexokinase 1 | 12060 | -0.129 | 0.0074 | No |
| 19 | PFKM | PFKM Entrez, Source | phosphofructokinase, muscle | 12804 | -0.226 | 0.0404 | No |
