Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | GN_CAMP_GRANULOSA_DN |
| Enrichment Score (ES) | -0.62175465 |
| Normalized Enrichment Score (NES) | -1.747885 |
| Nominal p-value | 0.0016891892 |
| FDR q-value | 0.047472406 |
| FWER p-Value | 0.999 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | RGS5 | RGS5 Entrez, Source | regulator of G-protein signalling 5 | 256 | 0.285 | 0.0372 | No |
| 2 | FLNC | FLNC Entrez, Source | filamin C, gamma (actin binding protein 280) | 1014 | 0.144 | 0.0088 | No |
| 3 | CASP4 | CASP4 Entrez, Source | caspase 4, apoptosis-related cysteine peptidase | 2168 | 0.089 | -0.0602 | No |
| 4 | DHRS3 | DHRS3 Entrez, Source | dehydrogenase/reductase (SDR family) member 3 | 2353 | 0.084 | -0.0575 | No |
| 5 | PDLIM3 | PDLIM3 Entrez, Source | PDZ and LIM domain 3 | 2579 | 0.077 | -0.0591 | No |
| 6 | STAT1 | STAT1 Entrez, Source | signal transducer and activator of transcription 1, 91kDa | 3416 | 0.058 | -0.1105 | No |
| 7 | PRKD1 | PRKD1 Entrez, Source | protein kinase D1 | 3605 | 0.054 | -0.1140 | No |
| 8 | RANGAP1 | RANGAP1 Entrez, Source | Ran GTPase activating protein 1 | 4842 | 0.032 | -0.2006 | No |
| 9 | CAP2 | CAP2 Entrez, Source | CAP, adenylate cyclase-associated protein, 2 (yeast) | 4920 | 0.030 | -0.2004 | No |
| 10 | AKAP12 | AKAP12 Entrez, Source | A kinase (PRKA) anchor protein (gravin) 12 | 5319 | 0.024 | -0.2254 | No |
| 11 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 6158 | 0.012 | -0.2860 | No |
| 12 | ITGB5 | ITGB5 Entrez, Source | integrin, beta 5 | 8308 | -0.020 | -0.4435 | No |
| 13 | AXL | AXL Entrez, Source | AXL receptor tyrosine kinase | 8404 | -0.021 | -0.4464 | No |
| 14 | PTPRE | PTPRE Entrez, Source | protein tyrosine phosphatase, receptor type, E | 8704 | -0.026 | -0.4636 | No |
| 15 | PLCL1 | PLCL1 Entrez, Source | phospholipase C-like 1 | 10259 | -0.058 | -0.5689 | No |
| 16 | RGS4 | RGS4 Entrez, Source | regulator of G-protein signalling 4 | 10391 | -0.061 | -0.5666 | No |
| 17 | TRIB1 | TRIB1 Entrez, Source | tribbles homolog 1 (Drosophila) | 10667 | -0.069 | -0.5736 | No |
| 18 | DYRK3 | DYRK3 Entrez, Source | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 10779 | -0.072 | -0.5678 | No |
| 19 | TNFRSF11B | TNFRSF11B Entrez, Source | tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) | 11055 | -0.080 | -0.5725 | No |
| 20 | ACTG2 | ACTG2 Entrez, Source | actin, gamma 2, smooth muscle, enteric | 11475 | -0.099 | -0.5845 | No |
| 21 | KIDINS220 | KIDINS220 Entrez, Source | - | 11972 | -0.123 | -0.5974 | Yes |
| 22 | NPC2 | NPC2 Entrez, Source | Niemann-Pick disease, type C2 | 12096 | -0.131 | -0.5807 | Yes |
| 23 | PAWR | PAWR Entrez, Source | PRKC, apoptosis, WT1, regulator | 12264 | -0.145 | -0.5646 | Yes |
| 24 | ACTA2 | ACTA2 Entrez, Source | actin, alpha 2, smooth muscle, aorta | 12537 | -0.177 | -0.5501 | Yes |
| 25 | ARL6IP5 | ARL6IP5 Entrez, Source | ADP-ribosylation-like factor 6 interacting protein 5 | 12549 | -0.178 | -0.5156 | Yes |
| 26 | PPP3R1 | PPP3R1 Entrez, Source | protein phosphatase 3 (formerly 2B), regulatory subunit B, 19kDa, alpha isoform (calcineurin B, type I) | 12578 | -0.181 | -0.4820 | Yes |
| 27 | SH3BP4 | SH3BP4 Entrez, Source | SH3-domain binding protein 4 | 12682 | -0.201 | -0.4499 | Yes |
| 28 | TYRO3 | TYRO3 Entrez, Source | TYRO3 protein tyrosine kinase | 12984 | -0.284 | -0.4163 | Yes |
| 29 | ACTN1 | ACTN1 Entrez, Source | actinin, alpha 1 | 13279 | -0.655 | -0.3089 | Yes |
| 30 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 13340 | -1.586 | 0.0002 | Yes |
