Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | HADDAD_CD45CD7_PLUS_VS_MINUS_DN |
| Enrichment Score (ES) | -0.59768444 |
| Normalized Enrichment Score (NES) | -1.8563797 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.028326152 |
| FWER p-Value | 0.783 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | INPP4B | INPP4B Entrez, Source | inositol polyphosphate-4-phosphatase, type II, 105kDa | 895 | 0.153 | -0.0446 | No |
| 2 | HSPA5 | HSPA5 Entrez, Source | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 909 | 0.152 | -0.0229 | No |
| 3 | KLF9 | KLF9 Entrez, Source | Kruppel-like factor 9 | 1556 | 0.110 | -0.0551 | No |
| 4 | DLK1 | DLK1 Entrez, Source | delta-like 1 homolog (Drosophila) | 1871 | 0.099 | -0.0641 | No |
| 5 | CRHBP | CRHBP Entrez, Source | corticotropin releasing hormone binding protein | 1910 | 0.097 | -0.0526 | No |
| 6 | ANK3 | ANK3 Entrez, Source | ankyrin 3, node of Ranvier (ankyrin G) | 1923 | 0.097 | -0.0391 | No |
| 7 | CHN2 | CHN2 Entrez, Source | chimerin (chimaerin) 2 | 1966 | 0.095 | -0.0282 | No |
| 8 | ALDH1A1 | ALDH1A1 Entrez, Source | aldehyde dehydrogenase 1 family, member A1 | 2239 | 0.087 | -0.0358 | No |
| 9 | GRK5 | GRK5 Entrez, Source | G protein-coupled receptor kinase 5 | 2743 | 0.073 | -0.0628 | No |
| 10 | STCH | STCH Entrez, Source | stress 70 protein chaperone, microsome-associated, 60kDa | 4413 | 0.039 | -0.1826 | No |
| 11 | CFH | CFH Entrez, Source | complement factor H | 4536 | 0.037 | -0.1862 | No |
| 12 | GP1BB /// SEPT5 | 4538 | 0.037 | -0.1808 | No | ||
| 13 | HMGA2 | HMGA2 Entrez, Source | high mobility group AT-hook 2 | 5052 | 0.028 | -0.2152 | No |
| 14 | MDK | MDK Entrez, Source | midkine (neurite growth-promoting factor 2) | 5277 | 0.025 | -0.2283 | No |
| 15 | NPR3 | NPR3 Entrez, Source | natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) | 5375 | 0.024 | -0.2321 | No |
| 16 | HTR1F | HTR1F Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 1F | 5788 | 0.018 | -0.2605 | No |
| 17 | FOXO1A | FOXO1A Entrez, Source | forkhead box O1A (rhabdomyosarcoma) | 5846 | 0.017 | -0.2623 | No |
| 18 | ARG2 | ARG2 Entrez, Source | arginase, type II | 6580 | 0.006 | -0.3167 | No |
| 19 | PHLPP | PHLPP Entrez, Source | PH domain and leucine rich repeat protein phosphatase | 6904 | 0.001 | -0.3408 | No |
| 20 | COL5A1 | COL5A1 Entrez, Source | collagen, type V, alpha 1 | 7132 | -0.002 | -0.3575 | No |
| 21 | SMARCA2 | SMARCA2 Entrez, Source | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 | 7445 | -0.007 | -0.3801 | No |
| 22 | ZNF148 | ZNF148 Entrez, Source | zinc finger protein 148 | 7480 | -0.007 | -0.3816 | No |
| 23 | HLF | HLF Entrez, Source | hepatic leukemia factor | 7695 | -0.010 | -0.3961 | No |
| 24 | BCLAF1 | BCLAF1 Entrez, Source | BCL2-associated transcription factor 1 | 7866 | -0.013 | -0.4070 | No |
| 25 | PDZD2 | PDZD2 Entrez, Source | PDZ domain containing 2 | 7990 | -0.015 | -0.4140 | No |
| 26 | CACNB2 | CACNB2 Entrez, Source | calcium channel, voltage-dependent, beta 2 subunit | 8013 | -0.015 | -0.4134 | No |
| 27 | GATA3 | GATA3 Entrez, Source | GATA binding protein 3 | 8231 | -0.019 | -0.4270 | No |
| 28 | SERPINI1 | SERPINI1 Entrez, Source | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | 9454 | -0.041 | -0.5129 | No |
| 29 | ILF3 | ILF3 Entrez, Source | interleukin enhancer binding factor 3, 90kDa | 10199 | -0.057 | -0.5604 | No |
| 30 | FAM3C | FAM3C Entrez, Source | family with sequence similarity 3, member C | 10235 | -0.058 | -0.5545 | No |
| 31 | PLCB4 | PLCB4 Entrez, Source | phospholipase C, beta 4 | 10512 | -0.064 | -0.5657 | No |
| 32 | PSEN2 | PSEN2 Entrez, Source | presenilin 2 (Alzheimer disease 4) | 10691 | -0.070 | -0.5688 | No |
| 33 | PDE4B | PDE4B Entrez, Source | phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila) | 10834 | -0.073 | -0.5686 | No |
| 34 | PRG2 | PRG2 Entrez, Source | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 11222 | -0.087 | -0.5848 | Yes |
| 35 | LAPTM4B | LAPTM4B Entrez, Source | lysosomal associated protein transmembrane 4 beta | 11373 | -0.094 | -0.5822 | Yes |
| 36 | DDX17 | DDX17 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | 11390 | -0.094 | -0.5694 | Yes |
| 37 | F2RL1 | F2RL1 Entrez, Source | coagulation factor II (thrombin) receptor-like 1 | 11450 | -0.098 | -0.5593 | Yes |
| 38 | MLLT3 | MLLT3 Entrez, Source | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | 11753 | -0.111 | -0.5655 | Yes |
| 39 | PTK2 | PTK2 Entrez, Source | PTK2 protein tyrosine kinase 2 | 11904 | -0.119 | -0.5591 | Yes |
| 40 | BAG3 | BAG3 Entrez, Source | BCL2-associated athanogene 3 | 11984 | -0.124 | -0.5467 | Yes |
| 41 | RASA1 | RASA1 Entrez, Source | RAS p21 protein activator (GTPase activating protein) 1 | 11988 | -0.124 | -0.5285 | Yes |
| 42 | PTPRD | PTPRD Entrez, Source | protein tyrosine phosphatase, receptor type, D | 12216 | -0.141 | -0.5246 | Yes |
| 43 | MSH2 | MSH2 Entrez, Source | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 12432 | -0.162 | -0.5168 | Yes |
| 44 | ARMCX2 | ARMCX2 Entrez, Source | armadillo repeat containing, X-linked 2 | 12467 | -0.166 | -0.4947 | Yes |
| 45 | TJP2 | TJP2 Entrez, Source | tight junction protein 2 (zona occludens 2) | 12531 | -0.176 | -0.4733 | Yes |
| 46 | PPM1H | PPM1H Entrez, Source | protein phosphatase 1H (PP2C domain containing) | 12703 | -0.205 | -0.4557 | Yes |
| 47 | MPDZ | MPDZ Entrez, Source | multiple PDZ domain protein | 12723 | -0.209 | -0.4261 | Yes |
| 48 | HSPB1 | HSPB1 Entrez, Source | heat shock 27kDa protein 1 | 12847 | -0.236 | -0.4003 | Yes |
| 49 | MYH10 | MYH10 Entrez, Source | myosin, heavy chain 10, non-muscle | 12969 | -0.279 | -0.3680 | Yes |
| 50 | TIMP3 | TIMP3 Entrez, Source | TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory) | 12978 | -0.283 | -0.3265 | Yes |
| 51 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 13011 | -0.297 | -0.2848 | Yes |
| 52 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 13204 | -0.471 | -0.2292 | Yes |
| 53 | BEX1 | BEX1 Entrez, Source | brain expressed, X-linked 1 | 13291 | -0.715 | -0.1294 | Yes |
| 54 | LOX | LOX Entrez, Source | lysyl oxidase | 13315 | -0.896 | 0.0020 | Yes |
