Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_72h_versus_single_gel_72h.class.cls
#double_gel_72h_versus_single_gel_72h_repos
Phenotypeclass.cls#double_gel_72h_versus_single_gel_72h_repos
Upregulated in classdouble_gel_72h
GeneSetHCC_SURVIVAL_GOOD_VS_POOR_UP
Enrichment Score (ES)0.7287434
Normalized Enrichment Score (NES)2.7799962
Nominal p-value0.0
FDR q-value0.0
FWER p-Value0.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: HCC_SURVIVAL_GOOD_VS_POOR_UP   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1EHHADHEHHADH
Entrez,  Source
enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase60.9080.0495Yes
2SLC27A5SLC27A5
Entrez,  Source
solute carrier family 27 (fatty acid transporter), member 590.7790.0922Yes
3PKLRPKLR
Entrez,  Source
pyruvate kinase, liver and RBC310.5610.1215Yes
4GLYATGLYAT
Entrez,  Source
glycine-N-acyltransferase330.5540.1519Yes
5AQP9AQP9
Entrez,  Source
aquaporin 9380.5300.1807Yes
6OTCOTC
Entrez,  Source
ornithine carbamoyltransferase440.5060.2082Yes
7CDO1CDO1
Entrez,  Source
cysteine dioxygenase, type I580.4840.2338Yes
8C4BPBC4BPB
Entrez,  Source
complement component 4 binding protein, beta650.4770.2596Yes
9DPYSDPYS
Entrez,  Source
dihydropyrimidinase900.4250.2812Yes
10SERPIND1SERPIND1
Entrez,  Source
serpin peptidase inhibitor, clade D (heparin cofactor), member 1920.4240.3045Yes
11KHKKHK
Entrez,  Source
ketohexokinase (fructokinase)930.4220.3277Yes
12ACOX2ACOX2
Entrez,  Source
acyl-Coenzyme A oxidase 2, branched chain950.4190.3507Yes
13CES1CES1
Entrez,  Source
carboxylesterase 1 (monocyte/macrophage serine esterase 1)1180.3940.3707Yes
14HGDHGD
Entrez,  Source
homogentisate 1,2-dioxygenase (homogentisate oxidase)1260.3850.3913Yes
15G6PCG6PC
Entrez,  Source
glucose-6-phosphatase, catalytic subunit1290.3830.4123Yes
16LPIN1LPIN1
Entrez,  Source
lipin 11330.3780.4329Yes
17PCPC
Entrez,  Source
pyruvate carboxylase1550.3470.4504Yes
18ASGR1ASGR1
Entrez,  Source
asialoglycoprotein receptor 11890.3190.4655Yes
19AOX1AOX1
Entrez,  Source
aldehyde oxidase 12010.3090.4816Yes
20CPT2CPT2
Entrez,  Source
carnitine palmitoyltransferase II2070.3070.4981Yes
21CABC1CABC1
Entrez,  Source
chaperone, ABC1 activity of bc1 complex homolog (S. pombe)2170.3010.5140Yes
22IL6RIL6R
Entrez,  Source
interleukin 6 receptor2640.2810.5260Yes
23F10F10
Entrez,  Source
coagulation factor X3420.2510.5340Yes
24SLC38A3SLC38A3
Entrez,  Source
solute carrier family 38, member 33570.2450.5465Yes
25ABCG5ABCG5
Entrez,  Source
ATP-binding cassette, sub-family G (WHITE), member 5 (sterolin 1)3670.2440.5592Yes
26SLC25A10SLC25A10
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 103780.2400.5716Yes
27ALAS1ALAS1
Entrez,  Source
aminolevulinate, delta-, synthase 14190.2240.5810Yes
28MSRAMSRA
Entrez,  Source
methionine sulfoxide reductase A4280.2220.5926Yes
29INSIG1INSIG1
Entrez,  Source
insulin induced gene 14850.2070.5997Yes
30MVKMVK
Entrez,  Source
mevalonate kinase (mevalonic aciduria)5780.1880.6032Yes
31TTPATTPA
Entrez,  Source
tocopherol (alpha) transfer protein (ataxia (Friedreich-like) with vitamin E deficiency)5810.1880.6133Yes
32BAATBAAT
Entrez,  Source
bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase)5970.1860.6225Yes
33NDRG2NDRG2
Entrez,  Source
NDRG family member 26100.1850.6317Yes
34PAHPAH
Entrez,  Source
phenylalanine hydroxylase6280.1820.6405Yes
35ECHS1ECHS1
Entrez,  Source
enoyl Coenzyme A hydratase, short chain, 1, mitochondrial6330.1820.6502Yes
36SERPINC1SERPINC1
Entrez,  Source
serpin peptidase inhibitor, clade C (antithrombin), member 16900.1750.6556Yes
37MASP2MASP2
Entrez,  Source
mannan-binding lectin serine peptidase 27180.1710.6630Yes
38INSRINSR
Entrez,  Source
insulin receptor7350.1690.6710Yes
39MRPL46MRPL46
Entrez,  Source
mitochondrial ribosomal protein L467430.1680.6798Yes
40PCYT2PCYT2
Entrez,  Source
phosphate cytidylyltransferase 2, ethanolamine7480.1680.6887Yes
41HAGHHAGH
Entrez,  Source
hydroxyacylglutathione hydrolase8190.1610.6922Yes
42CRYL1CRYL1
Entrez,  Source
crystallin, lambda 19190.1510.6931Yes
43ACFACF
Entrez,  Source
-9830.1460.6964Yes
44STARD10STARD10
Entrez,  Source
START domain containing 109990.1450.7032Yes
45DCXRDCXR
Entrez,  Source
dicarbonyl/L-xylulose reductase10100.1440.7104Yes
46SLC6A12SLC6A12
Entrez,  Source
solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 1210190.1430.7177Yes
47HADH2HADH2
Entrez,  Source
hydroxyacyl-Coenzyme A dehydrogenase, type II10950.1370.7196Yes
48AMACRAMACR
Entrez,  Source
alpha-methylacyl-CoA racemase11430.1340.7234Yes
49CES3CES3
Entrez,  Source
carboxylesterase 3 (brain)11830.1310.7277Yes
50GJB1GJB1
Entrez,  Source
gap junction protein, beta 1, 32kDa (connexin 32, Charcot-Marie-Tooth neuropathy, X-linked)12930.1240.7263Yes
51AMTAMT
Entrez,  Source
aminomethyltransferase13970.1190.7250Yes
52SEC14L2SEC14L2
Entrez,  Source
SEC14-like 2 (S. cerevisiae)14340.1170.7287Yes
53F12F12
Entrez,  Source
coagulation factor XII (Hageman factor)18080.1010.7061No
54APOC3APOC3
Entrez,  Source
apolipoprotein C-III21760.0890.6833No
55FMO3FMO3
Entrez,  Source
flavin containing monooxygenase 323220.0840.6770No
56SERPINF1SERPINF1
Entrez,  Source
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 123450.0840.6800No
57SLC2A2SLC2A2
Entrez,  Source
solute carrier family 2 (facilitated glucose transporter), member 224590.0810.6759No
58MST1MST1
Entrez,  Source
macrophage stimulating 1 (hepatocyte growth factor-like)25140.0790.6762No
59SRD5A1SRD5A1
Entrez,  Source
steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)25610.0780.6770No
60ZP3ZP3
Entrez,  Source
zona pellucida glycoprotein 3 (sperm receptor)29880.0670.6485No
61NDUFS2NDUFS2
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)31720.0630.6382No
62SERPING1SERPING1
Entrez,  Source
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary)33070.0600.6314No
63PCCBPCCB
Entrez,  Source
propionyl Coenzyme A carboxylase, beta polypeptide34170.0580.6263No
64EPHX1EPHX1
Entrez,  Source
epoxide hydrolase 1, microsomal (xenobiotic)41040.0450.5770No
65CPB2CPB2
Entrez,  Source
carboxypeptidase B2 (plasma, carboxypeptidase U)41450.0440.5764No
66APCSAPCS
Entrez,  Source
amyloid P component, serum42010.0430.5746No
67HPDHPD
Entrez,  Source
4-hydroxyphenylpyruvate dioxygenase43830.0400.5631No
68IVDIVD
Entrez,  Source
isovaleryl Coenzyme A dehydrogenase47830.0330.5348No
69EGLN2EGLN2
Entrez,  Source
egl nine homolog 2 (C. elegans)52830.0250.4985No
70CES2CES2
Entrez,  Source
carboxylesterase 2 (intestine, liver)54180.0230.4896No
71APOA5APOA5
Entrez,  Source
apolipoprotein A-V58150.0170.4607No
72ACADSACADS
Entrez,  Source
acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain58860.0160.4563No
73PCK1PCK1
Entrez,  Source
phosphoenolpyruvate carboxykinase 1 (soluble)60260.0140.4466No
74PRDX6PRDX6
Entrez,  Source
peroxiredoxin 667680.0030.3908No
75ITPR2ITPR2
Entrez,  Source
inositol 1,4,5-triphosphate receptor, type 27164-0.0030.3611No
76MYRIPMYRIP
Entrez,  Source
myosin VIIA and Rab interacting protein7534-0.0080.3337No
77ABHD6ABHD6
Entrez,  Source
abhydrolase domain containing 67579-0.0090.3309No
78SULT2A1SULT2A1
Entrez,  Source
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 18105-0.0160.2921No
79PPAP2APPAP2A
Entrez,  Source
phosphatidic acid phosphatase type 2A8226-0.0180.2841No
80ABCG8ABCG8
Entrez,  Source
ATP-binding cassette, sub-family G (WHITE), member 8 (sterolin 2)10112-0.0550.1448No
81WNT11WNT11
Entrez,  Source
wingless-type MMTV integration site family, member 1110113-0.0550.1478No
82CYP3A4CYP3A4
Entrez,  Source
cytochrome P450, family 3, subfamily A, polypeptide 410311-0.0590.1362No
83ENPP5ENPP5
Entrez,  Source
ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative function)10803-0.0730.1031No
84CABIN1CABIN1
Entrez,  Source
-10919-0.0760.0986No
85ARAR
Entrez,  Source
androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease)10940-0.0770.1013No
86C2C2
Entrez,  Source
complement component 211048-0.0800.0977No
87MUCDHLMUCDHL
Entrez,  Source
mucin and cadherin-like11118-0.0830.0970No
88SELENBP1SELENBP1
Entrez,  Source
selenium binding protein 111162-0.0840.0984No
89NF1NF1
Entrez,  Source
neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease)11882-0.1180.0506No
90KLK3KLK3
Entrez,  Source
kallikrein 3, (prostate specific antigen)11915-0.1190.0548No
91ABCC2ABCC2
Entrez,  Source
ATP-binding cassette, sub-family C (CFTR/MRP), member 212020-0.1260.0539No
92RGNRGN
Entrez,  Source
regucalcin (senescence marker protein-30)12427-0.1610.0321No
93SGPL1SGPL1
Entrez,  Source
sphingosine-1-phosphate lyase 112434-0.1620.0406No
94MPDZMPDZ
Entrez,  Source
multiple PDZ domain protein12723-0.2090.0303No
95CRATCRAT
Entrez,  Source
carnitine acetyltransferase13012-0.2970.0249No
Table: GSEA details [plain text format]



Fig 2: HCC_SURVIVAL_GOOD_VS_POOR_UP   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: HCC_SURVIVAL_GOOD_VS_POOR_UP: Random ES distribution   
Gene set null distribution of ES for HCC_SURVIVAL_GOOD_VS_POOR_UP