Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | HETEROCYCLE_METABOLIC_PROCESS |
| Enrichment Score (ES) | 0.6743641 |
| Normalized Enrichment Score (NES) | 1.6982976 |
| Nominal p-value | 0.0043010754 |
| FDR q-value | 0.036270093 |
| FWER p-Value | 0.999 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FTCD | FTCD Entrez, Source | formiminotransferase cyclodeaminase | 15 | 0.731 | 0.3474 | Yes |
| 2 | ALAS1 | ALAS1 Entrez, Source | aminolevulinate, delta-, synthase 1 | 419 | 0.224 | 0.4241 | Yes |
| 3 | ALDH6A1 | ALDH6A1 Entrez, Source | aldehyde dehydrogenase 6 family, member A1 | 445 | 0.217 | 0.5259 | Yes |
| 4 | ALDH1L1 | ALDH1L1 Entrez, Source | aldehyde dehydrogenase 1 family, member L1 | 465 | 0.211 | 0.6251 | Yes |
| 5 | ALAD | ALAD Entrez, Source | aminolevulinate, delta-, dehydratase | 826 | 0.160 | 0.6744 | Yes |
| 6 | CPOX | CPOX Entrez, Source | coproporphyrinogen oxidase | 2946 | 0.068 | 0.5476 | No |
| 7 | P4HB | P4HB Entrez, Source | procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide | 3536 | 0.055 | 0.5298 | No |
| 8 | GMPS | GMPS Entrez, Source | guanine monphosphate synthetase | 3595 | 0.054 | 0.5511 | No |
| 9 | UROS | UROS Entrez, Source | uroporphyrinogen III synthase (congenital erythropoietic porphyria) | 3820 | 0.049 | 0.5578 | No |
| 10 | BLVRA | BLVRA Entrez, Source | biliverdin reductase A | 4380 | 0.040 | 0.5348 | No |
| 11 | ALAS2 | ALAS2 Entrez, Source | aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia) | 5606 | 0.020 | 0.4526 | No |
| 12 | PRPS1 | PRPS1 Entrez, Source | phosphoribosyl pyrophosphate synthetase 1 | 6821 | 0.002 | 0.3626 | No |
| 13 | PAICS | PAICS Entrez, Source | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | 8385 | -0.021 | 0.2554 | No |
| 14 | INDO | INDO Entrez, Source | indoleamine-pyrrole 2,3 dioxygenase | 9012 | -0.032 | 0.2239 | No |
| 15 | COX15 | COX15 Entrez, Source | COX15 homolog, cytochrome c oxidase assembly protein (yeast) | 10424 | -0.062 | 0.1476 | No |
| 16 | HPRT1 | HPRT1 Entrez, Source | hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome) | 10730 | -0.071 | 0.1584 | No |
| 17 | TSPO | TSPO Entrez, Source | translocator protein (18kDa) | 11004 | -0.079 | 0.1754 | No |
