Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | HOFFMANN_BIVSBII_BI_TABLE2 |
| Enrichment Score (ES) | -0.5784415 |
| Normalized Enrichment Score (NES) | -2.0783274 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0024192852 |
| FWER p-Value | 0.041 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 110 | 0.403 | 0.0181 | No |
| 2 | RBP4 | RBP4 Entrez, Source | retinol binding protein 4, plasma | 229 | 0.294 | 0.0285 | No |
| 3 | ABCA1 | ABCA1 Entrez, Source | ATP-binding cassette, sub-family A (ABC1), member 1 | 355 | 0.248 | 0.0353 | No |
| 4 | SPINK1 | SPINK1 Entrez, Source | serine peptidase inhibitor, Kazal type 1 | 590 | 0.187 | 0.0298 | No |
| 5 | AZIN1 | AZIN1 Entrez, Source | antizyme inhibitor 1 | 1515 | 0.112 | -0.0326 | No |
| 6 | EDN2 | EDN2 Entrez, Source | endothelin 2 | 1518 | 0.112 | -0.0254 | No |
| 7 | TUBB3 | TUBB3 Entrez, Source | tubulin, beta 3 | 1557 | 0.110 | -0.0211 | No |
| 8 | IL4R | IL4R Entrez, Source | interleukin 4 receptor | 1697 | 0.105 | -0.0247 | No |
| 9 | HCK | HCK Entrez, Source | hemopoietic cell kinase | 1900 | 0.097 | -0.0336 | No |
| 10 | ANK3 | ANK3 Entrez, Source | ankyrin 3, node of Ranvier (ankyrin G) | 1923 | 0.097 | -0.0289 | No |
| 11 | HES1 | HES1 Entrez, Source | hairy and enhancer of split 1, (Drosophila) | 2287 | 0.085 | -0.0507 | No |
| 12 | CCNE1 | CCNE1 Entrez, Source | cyclin E1 | 2560 | 0.078 | -0.0662 | No |
| 13 | ARL1 | ARL1 Entrez, Source | ADP-ribosylation factor-like 1 | 2616 | 0.076 | -0.0654 | No |
| 14 | NUCKS1 | NUCKS1 Entrez, Source | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 2686 | 0.074 | -0.0657 | No |
| 15 | RABEP1 | RABEP1 Entrez, Source | rabaptin, RAB GTPase binding effector protein 1 | 2784 | 0.072 | -0.0684 | No |
| 16 | HSPB8 | HSPB8 Entrez, Source | heat shock 22kDa protein 8 | 3246 | 0.061 | -0.0992 | No |
| 17 | RAMP1 | RAMP1 Entrez, Source | receptor (calcitonin) activity modifying protein 1 | 3434 | 0.057 | -0.1096 | No |
| 18 | PSAT1 | PSAT1 Entrez, Source | phosphoserine aminotransferase 1 | 3569 | 0.054 | -0.1162 | No |
| 19 | COIL | COIL Entrez, Source | coilin | 3588 | 0.054 | -0.1140 | No |
| 20 | NELF | NELF Entrez, Source | nasal embryonic LHRH factor | 3738 | 0.051 | -0.1219 | No |
| 21 | CD2 | CD2 Entrez, Source | CD2 molecule | 3794 | 0.050 | -0.1228 | No |
| 22 | SEPP1 | SEPP1 Entrez, Source | selenoprotein P, plasma, 1 | 4188 | 0.043 | -0.1497 | No |
| 23 | AARS | AARS Entrez, Source | alanyl-tRNA synthetase | 4275 | 0.042 | -0.1534 | No |
| 24 | CDKN3 | CDKN3 Entrez, Source | cyclin-dependent kinase inhibitor 3 (CDK2-associated dual specificity phosphatase) | 4390 | 0.040 | -0.1595 | No |
| 25 | TBXA2R | TBXA2R Entrez, Source | thromboxane A2 receptor | 4498 | 0.038 | -0.1651 | No |
| 26 | HSD11B2 | HSD11B2 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 2 | 4542 | 0.037 | -0.1659 | No |
| 27 | FBP2 | FBP2 Entrez, Source | fructose-1,6-bisphosphatase 2 | 4892 | 0.031 | -0.1902 | No |
| 28 | WDSUB1 | WDSUB1 Entrez, Source | WD repeat, sterile alpha motif and U-box domain containing 1 | 5085 | 0.028 | -0.2029 | No |
| 29 | ATP5D | ATP5D Entrez, Source | ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit | 5323 | 0.024 | -0.2192 | No |
| 30 | SLC29A1 | SLC29A1 Entrez, Source | solute carrier family 29 (nucleoside transporters), member 1 | 5361 | 0.024 | -0.2205 | No |
| 31 | ANP32B | ANP32B Entrez, Source | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 5389 | 0.023 | -0.2210 | No |
| 32 | WT1 | WT1 Entrez, Source | Wilms tumor 1 | 5408 | 0.023 | -0.2208 | No |
| 33 | MDN1 | MDN1 Entrez, Source | MDN1, midasin homolog (yeast) | 5490 | 0.022 | -0.2255 | No |
| 34 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 5597 | 0.020 | -0.2322 | No |
| 35 | CLCN2 | CLCN2 Entrez, Source | chloride channel 2 | 5793 | 0.017 | -0.2458 | No |
| 36 | EVL | EVL Entrez, Source | Enah/Vasp-like | 5854 | 0.016 | -0.2493 | No |
| 37 | BRCA2 | BRCA2 Entrez, Source | breast cancer 2, early onset | 5924 | 0.015 | -0.2535 | No |
| 38 | HSPD1 | HSPD1 Entrez, Source | heat shock 60kDa protein 1 (chaperonin) | 6242 | 0.011 | -0.2768 | No |
| 39 | IL4 | IL4 Entrez, Source | interleukin 4 | 6466 | 0.007 | -0.2932 | No |
| 40 | RPL10 | RPL10 Entrez, Source | ribosomal protein L10 | 6569 | 0.006 | -0.3005 | No |
| 41 | ANP32E | ANP32E Entrez, Source | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 6623 | 0.005 | -0.3042 | No |
| 42 | GSPT1 | GSPT1 Entrez, Source | G1 to S phase transition 1 | 6717 | 0.004 | -0.3110 | No |
| 43 | MYH11 | MYH11 Entrez, Source | myosin, heavy chain 11, smooth muscle | 6721 | 0.004 | -0.3110 | No |
| 44 | SCN1B | SCN1B Entrez, Source | sodium channel, voltage-gated, type I, beta | 6937 | 0.001 | -0.3272 | No |
| 45 | GALT | GALT Entrez, Source | galactose-1-phosphate uridylyltransferase | 7124 | -0.002 | -0.3411 | No |
| 46 | GJA4 | GJA4 Entrez, Source | gap junction protein, alpha 4, 37kDa (connexin 37) | 7260 | -0.004 | -0.3511 | No |
| 47 | LDHA | LDHA Entrez, Source | lactate dehydrogenase A | 7676 | -0.010 | -0.3818 | No |
| 48 | NUDC | NUDC Entrez, Source | nuclear distribution gene C homolog (A. nidulans) | 7733 | -0.011 | -0.3853 | No |
| 49 | XPO1 | XPO1 Entrez, Source | exportin 1 (CRM1 homolog, yeast) | 7735 | -0.011 | -0.3847 | No |
| 50 | SPIN | SPIN Entrez, Source | spindlin | 7941 | -0.014 | -0.3992 | No |
| 51 | CRIP2 | CRIP2 Entrez, Source | cysteine-rich protein 2 | 8154 | -0.017 | -0.4141 | No |
| 52 | PPIA | PPIA Entrez, Source | peptidylprolyl isomerase A (cyclophilin A) | 8225 | -0.018 | -0.4182 | No |
| 53 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 8319 | -0.020 | -0.4239 | No |
| 54 | CHAF1B | CHAF1B Entrez, Source | chromatin assembly factor 1, subunit B (p60) | 8597 | -0.025 | -0.4433 | No |
| 55 | E2F8 | E2F8 Entrez, Source | E2F transcription factor 8 | 8633 | -0.025 | -0.4442 | No |
| 56 | SSX2IP | SSX2IP Entrez, Source | synovial sarcoma, X breakpoint 2 interacting protein | 8915 | -0.030 | -0.4635 | No |
| 57 | IGH-1A | 8967 | -0.032 | -0.4653 | No | ||
| 58 | GPHN | GPHN Entrez, Source | gephyrin | 9059 | -0.033 | -0.4700 | No |
| 59 | TOP2A | TOP2A Entrez, Source | topoisomerase (DNA) II alpha 170kDa | 9129 | -0.035 | -0.4729 | No |
| 60 | CAMP | CAMP Entrez, Source | cathelicidin antimicrobial peptide | 9148 | -0.035 | -0.4720 | No |
| 61 | CDKN2C | CDKN2C Entrez, Source | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 9276 | -0.037 | -0.4791 | No |
| 62 | IER3 | IER3 Entrez, Source | immediate early response 3 | 9311 | -0.038 | -0.4792 | No |
| 63 | DNMT1 | DNMT1 Entrez, Source | DNA (cytosine-5-)-methyltransferase 1 | 9405 | -0.040 | -0.4836 | No |
| 64 | RAB4B | RAB4B Entrez, Source | RAB4B, member RAS oncogene family | 9418 | -0.040 | -0.4819 | No |
| 65 | KIF4A | KIF4A Entrez, Source | kinesin family member 4A | 9748 | -0.047 | -0.5037 | No |
| 66 | PSMC3 | PSMC3 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 3 | 9750 | -0.047 | -0.5007 | No |
| 67 | FHL1 | FHL1 Entrez, Source | four and a half LIM domains 1 | 9787 | -0.048 | -0.5003 | No |
| 68 | NT5DC2 | NT5DC2 Entrez, Source | 5'-nucleotidase domain containing 2 | 9788 | -0.048 | -0.4972 | No |
| 69 | PPP2CA | PPP2CA Entrez, Source | protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform | 9927 | -0.051 | -0.5043 | No |
| 70 | HDH | 9928 | -0.051 | -0.5010 | No | ||
| 71 | PPP1CA | PPP1CA Entrez, Source | protein phosphatase 1, catalytic subunit, alpha isoform | 10210 | -0.057 | -0.5185 | No |
| 72 | PSEN2 | PSEN2 Entrez, Source | presenilin 2 (Alzheimer disease 4) | 10691 | -0.070 | -0.5502 | No |
| 73 | ITGB7 | ITGB7 Entrez, Source | integrin, beta 7 | 10842 | -0.074 | -0.5567 | No |
| 74 | IDE | IDE Entrez, Source | insulin-degrading enzyme | 10869 | -0.074 | -0.5538 | No |
| 75 | FLIIH | 10916 | -0.076 | -0.5523 | No | ||
| 76 | IGSF10 | IGSF10 Entrez, Source | immunoglobulin superfamily, member 10 | 11023 | -0.079 | -0.5552 | No |
| 77 | EIF2AK2 | EIF2AK2 Entrez, Source | eukaryotic translation initiation factor 2-alpha kinase 2 | 11109 | -0.082 | -0.5562 | No |
| 78 | TUBB2C | TUBB2C Entrez, Source | tubulin, beta 2C | 11159 | -0.084 | -0.5544 | No |
| 79 | MYEF2 | MYEF2 Entrez, Source | myelin expression factor 2 | 11204 | -0.086 | -0.5521 | No |
| 80 | FEN1 | FEN1 Entrez, Source | flap structure-specific endonuclease 1 | 11249 | -0.088 | -0.5496 | No |
| 81 | LIG1 | LIG1 Entrez, Source | ligase I, DNA, ATP-dependent | 11631 | -0.106 | -0.5715 | Yes |
| 82 | BIRC3 | BIRC3 Entrez, Source | baculoviral IAP repeat-containing 3 | 11637 | -0.106 | -0.5649 | Yes |
| 83 | CKAP5 | CKAP5 Entrez, Source | cytoskeleton associated protein 5 | 11647 | -0.106 | -0.5586 | Yes |
| 84 | ANP32A | ANP32A Entrez, Source | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 11654 | -0.107 | -0.5521 | Yes |
| 85 | CAPN1 | CAPN1 Entrez, Source | calpain 1, (mu/I) large subunit | 11685 | -0.108 | -0.5472 | Yes |
| 86 | CASP3 | CASP3 Entrez, Source | caspase 3, apoptosis-related cysteine peptidase | 11736 | -0.111 | -0.5437 | Yes |
| 87 | CIT | CIT Entrez, Source | citron (rho-interacting, serine/threonine kinase 21) | 11752 | -0.111 | -0.5376 | Yes |
| 88 | JUN | JUN Entrez, Source | jun oncogene | 11756 | -0.111 | -0.5305 | Yes |
| 89 | AURKA | AURKA Entrez, Source | aurora kinase A | 11917 | -0.119 | -0.5348 | Yes |
| 90 | CDC20 | CDC20 Entrez, Source | CDC20 cell division cycle 20 homolog (S. cerevisiae) | 12256 | -0.144 | -0.5509 | Yes |
| 91 | H2AFX | H2AFX Entrez, Source | H2A histone family, member X | 12313 | -0.149 | -0.5453 | Yes |
| 92 | LSP1 | LSP1 Entrez, Source | lymphocyte-specific protein 1 | 12383 | -0.156 | -0.5403 | Yes |
| 93 | GSN | GSN Entrez, Source | gelsolin (amyloidosis, Finnish type) | 12398 | -0.157 | -0.5310 | Yes |
| 94 | RFC3 | RFC3 Entrez, Source | replication factor C (activator 1) 3, 38kDa | 12464 | -0.165 | -0.5251 | Yes |
| 95 | TMPO | TMPO Entrez, Source | thymopoietin | 12590 | -0.183 | -0.5225 | Yes |
| 96 | MMP14 | MMP14 Entrez, Source | matrix metallopeptidase 14 (membrane-inserted) | 12629 | -0.189 | -0.5129 | Yes |
| 97 | CD151 | CD151 Entrez, Source | CD151 molecule (Raph blood group) | 12732 | -0.210 | -0.5069 | Yes |
| 98 | KIFC1 | KIFC1 Entrez, Source | kinesin family member C1 | 12767 | -0.216 | -0.4952 | Yes |
| 99 | KIF2C | KIF2C Entrez, Source | kinesin family member 2C | 12815 | -0.228 | -0.4838 | Yes |
| 100 | CAPG | CAPG Entrez, Source | capping protein (actin filament), gelsolin-like | 12818 | -0.229 | -0.4690 | Yes |
| 101 | TRIP13 | TRIP13 Entrez, Source | thyroid hormone receptor interactor 13 | 12851 | -0.238 | -0.4558 | Yes |
| 102 | ACTN4 | ACTN4 Entrez, Source | actinin, alpha 4 | 12871 | -0.243 | -0.4413 | Yes |
| 103 | CCNB2 | CCNB2 Entrez, Source | cyclin B2 | 12949 | -0.272 | -0.4293 | Yes |
| 104 | RELN | RELN Entrez, Source | reelin | 12968 | -0.279 | -0.4123 | Yes |
| 105 | KIF22 | KIF22 Entrez, Source | kinesin family member 22 | 12985 | -0.285 | -0.3949 | Yes |
| 106 | HMMR | HMMR Entrez, Source | hyaluronan-mediated motility receptor (RHAMM) | 12987 | -0.285 | -0.3763 | Yes |
| 107 | TUBB | TUBB Entrez, Source | tubulin, beta | 13001 | -0.292 | -0.3581 | Yes |
| 108 | LGALS3 | LGALS3 Entrez, Source | lectin, galactoside-binding, soluble, 3 (galectin 3) | 13064 | -0.327 | -0.3413 | Yes |
| 109 | SMC4 | SMC4 Entrez, Source | structural maintenance of chromosomes 4 | 13078 | -0.337 | -0.3202 | Yes |
| 110 | AURKB | AURKB Entrez, Source | aurora kinase B | 13115 | -0.366 | -0.2989 | Yes |
| 111 | CCNB1 | CCNB1 Entrez, Source | cyclin B1 | 13131 | -0.385 | -0.2748 | Yes |
| 112 | CDC2A | 13232 | -0.520 | -0.2483 | Yes | ||
| 113 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13267 | -0.614 | -0.2105 | Yes |
| 114 | LIPC | LIPC Entrez, Source | lipase, hepatic | 13275 | -0.650 | -0.1685 | Yes |
| 115 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 13302 | -0.755 | -0.1209 | Yes |
| 116 | CCNA2 | CCNA2 Entrez, Source | cyclin A2 | 13314 | -0.890 | -0.0633 | Yes |
| 117 | PKIB | PKIB Entrez, Source | protein kinase (cAMP-dependent, catalytic) inhibitor beta | 13324 | -0.997 | 0.0014 | Yes |
