Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | HSA00010_GLYCOLYSIS_AND_GLUCONEOGENESIS |
| Enrichment Score (ES) | 0.48912656 |
| Normalized Enrichment Score (NES) | 1.6198287 |
| Nominal p-value | 0.0070588235 |
| FDR q-value | 0.06152774 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PKLR | PKLR Entrez, Source | pyruvate kinase, liver and RBC | 31 | 0.561 | 0.0931 | Yes |
| 2 | FBP1 | FBP1 Entrez, Source | fructose-1,6-bisphosphatase 1 | 43 | 0.515 | 0.1800 | Yes |
| 3 | ADH7 | ADH7 Entrez, Source | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide | 53 | 0.495 | 0.2636 | Yes |
| 4 | G6PC | G6PC Entrez, Source | glucose-6-phosphatase, catalytic subunit | 129 | 0.383 | 0.3232 | Yes |
| 5 | GCK | GCK Entrez, Source | glucokinase (hexokinase 4, maturity onset diabetes of the young 2) | 140 | 0.368 | 0.3851 | Yes |
| 6 | ADHFE1 | ADHFE1 Entrez, Source | alcohol dehydrogenase, iron containing, 1 | 163 | 0.343 | 0.4418 | Yes |
| 7 | PDHA2 | PDHA2 Entrez, Source | pyruvate dehydrogenase (lipoamide) alpha 2 | 414 | 0.227 | 0.4616 | Yes |
| 8 | PDHB | PDHB Entrez, Source | pyruvate dehydrogenase (lipoamide) beta | 563 | 0.190 | 0.4829 | Yes |
| 9 | ALDOB | ALDOB Entrez, Source | aldolase B, fructose-bisphosphate | 1007 | 0.144 | 0.4741 | Yes |
| 10 | ADH1A | ADH1A Entrez, Source | alcohol dehydrogenase 1A (class I), alpha polypeptide | 1116 | 0.136 | 0.4891 | Yes |
| 11 | GALM | GALM Entrez, Source | galactose mutarotase (aldose 1-epimerase) | 1687 | 0.105 | 0.4642 | No |
| 12 | ADH6 | ADH6 Entrez, Source | alcohol dehydrogenase 6 (class V) | 2053 | 0.092 | 0.4525 | No |
| 13 | PGM1 | PGM1 Entrez, Source | phosphoglucomutase 1 | 2063 | 0.092 | 0.4675 | No |
| 14 | ENO2 | ENO2 Entrez, Source | enolase 2 (gamma, neuronal) | 2893 | 0.069 | 0.4169 | No |
| 15 | DLD | DLD Entrez, Source | dihydrolipoamide dehydrogenase | 3142 | 0.063 | 0.4090 | No |
| 16 | HK2 | HK2 Entrez, Source | hexokinase 2 | 3553 | 0.055 | 0.3875 | No |
| 17 | ALDH7A1 | ALDH7A1 Entrez, Source | aldehyde dehydrogenase 7 family, member A1 | 3614 | 0.053 | 0.3921 | No |
| 18 | ADH4 | ADH4 Entrez, Source | alcohol dehydrogenase 4 (class II), pi polypeptide | 3800 | 0.050 | 0.3867 | No |
| 19 | ENO3 | ENO3 Entrez, Source | enolase 3 (beta, muscle) | 3849 | 0.049 | 0.3914 | No |
| 20 | ALDH3A2 | ALDH3A2 Entrez, Source | aldehyde dehydrogenase 3 family, member A2 | 4819 | 0.032 | 0.3240 | No |
| 21 | FBP2 | FBP2 Entrez, Source | fructose-1,6-bisphosphatase 2 | 4892 | 0.031 | 0.3239 | No |
| 22 | ALDH1B1 | ALDH1B1 Entrez, Source | aldehyde dehydrogenase 1 family, member B1 | 5218 | 0.026 | 0.3039 | No |
| 23 | GPI | GPI Entrez, Source | glucose phosphate isomerase | 5582 | 0.021 | 0.2801 | No |
| 24 | ALDOC | ALDOC Entrez, Source | aldolase C, fructose-bisphosphate | 5718 | 0.018 | 0.2731 | No |
| 25 | PDHA1 | PDHA1 Entrez, Source | pyruvate dehydrogenase (lipoamide) alpha 1 | 5797 | 0.017 | 0.2702 | No |
| 26 | ALDH2 | ALDH2 Entrez, Source | aldehyde dehydrogenase 2 family (mitochondrial) | 6175 | 0.012 | 0.2438 | No |
| 27 | LDHC | LDHC Entrez, Source | lactate dehydrogenase C | 6640 | 0.005 | 0.2097 | No |
| 28 | GAPDHS | GAPDHS Entrez, Source | glyceraldehyde-3-phosphate dehydrogenase, spermatogenic | 6929 | 0.001 | 0.1882 | No |
| 29 | BPGM | BPGM Entrez, Source | 2,3-bisphosphoglycerate mutase | 7060 | -0.001 | 0.1786 | No |
| 30 | AKR1A1 | AKR1A1 Entrez, Source | aldo-keto reductase family 1, member A1 (aldehyde reductase) | 7127 | -0.002 | 0.1740 | No |
| 31 | PGK1 | PGK1 Entrez, Source | phosphoglycerate kinase 1 | 7152 | -0.002 | 0.1726 | No |
| 32 | PGAM2 | PGAM2 Entrez, Source | phosphoglycerate mutase 2 (muscle) | 7429 | -0.006 | 0.1529 | No |
| 33 | LDHA | LDHA Entrez, Source | lactate dehydrogenase A | 7676 | -0.010 | 0.1361 | No |
| 34 | GAPDH | GAPDH Entrez, Source | glyceraldehyde-3-phosphate dehydrogenase | 7743 | -0.011 | 0.1330 | No |
| 35 | TPI1 | TPI1 Entrez, Source | triosephosphate isomerase 1 | 8236 | -0.019 | 0.0992 | No |
| 36 | LDHAL6B | LDHAL6B Entrez, Source | lactate dehydrogenase A-like 6B | 8335 | -0.020 | 0.0953 | No |
| 37 | ALDOA | ALDOA Entrez, Source | aldolase A, fructose-bisphosphate | 9779 | -0.047 | -0.0051 | No |
| 38 | ALDH3A1 | ALDH3A1 Entrez, Source | aldehyde dehydrogenase 3 family, memberA1 | 9824 | -0.048 | -0.0002 | No |
| 39 | PGAM1 | PGAM1 Entrez, Source | phosphoglycerate mutase 1 (brain) | 10612 | -0.067 | -0.0479 | No |
| 40 | ALDH9A1 | ALDH9A1 Entrez, Source | aldehyde dehydrogenase 9 family, member A1 | 10674 | -0.069 | -0.0408 | No |
| 41 | PFKL | PFKL Entrez, Source | phosphofructokinase, liver | 10756 | -0.071 | -0.0347 | No |
| 42 | DLAT | DLAT Entrez, Source | dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) | 10995 | -0.078 | -0.0393 | No |
| 43 | HK1 | HK1 Entrez, Source | hexokinase 1 | 12060 | -0.129 | -0.0974 | No |
| 44 | ALDH3B1 | ALDH3B1 Entrez, Source | aldehyde dehydrogenase 3 family, member B1 | 12784 | -0.220 | -0.1144 | No |
| 45 | PFKM | PFKM Entrez, Source | phosphofructokinase, muscle | 12804 | -0.226 | -0.0773 | No |
| 46 | LDHB | LDHB Entrez, Source | lactate dehydrogenase B | 13034 | -0.309 | -0.0418 | No |
| 47 | PFKP | PFKP Entrez, Source | phosphofructokinase, platelet | 13129 | -0.381 | 0.0160 | No |
