Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | HSA00020_CITRATE_CYCLE |
| Enrichment Score (ES) | 0.6734229 |
| Normalized Enrichment Score (NES) | 1.8547503 |
| Nominal p-value | 0.0021276595 |
| FDR q-value | 0.010401689 |
| FWER p-Value | 0.679 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PC | PC Entrez, Source | pyruvate carboxylase | 155 | 0.347 | 0.1645 | Yes |
| 2 | ACLY | ACLY Entrez, Source | ATP citrate lyase | 212 | 0.305 | 0.3149 | Yes |
| 3 | CLYBL | CLYBL Entrez, Source | citrate lyase beta like | 307 | 0.264 | 0.4418 | Yes |
| 4 | MDH1 | MDH1 Entrez, Source | malate dehydrogenase 1, NAD (soluble) | 1246 | 0.127 | 0.4358 | Yes |
| 5 | IDH1 | IDH1 Entrez, Source | isocitrate dehydrogenase 1 (NADP+), soluble | 1494 | 0.114 | 0.4749 | Yes |
| 6 | IDH3A | IDH3A Entrez, Source | isocitrate dehydrogenase 3 (NAD+) alpha | 1985 | 0.094 | 0.4860 | Yes |
| 7 | ACO1 | ACO1 Entrez, Source | aconitase 1, soluble | 2259 | 0.086 | 0.5092 | Yes |
| 8 | MDH2 | MDH2 Entrez, Source | malate dehydrogenase 2, NAD (mitochondrial) | 2409 | 0.082 | 0.5398 | Yes |
| 9 | SDHD | SDHD Entrez, Source | succinate dehydrogenase complex, subunit D, integral membrane protein | 2529 | 0.079 | 0.5708 | Yes |
| 10 | IDH3B | IDH3B Entrez, Source | isocitrate dehydrogenase 3 (NAD+) beta | 2648 | 0.075 | 0.6000 | Yes |
| 11 | SDHA | SDHA Entrez, Source | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 2780 | 0.072 | 0.6266 | Yes |
| 12 | ACO2 | ACO2 Entrez, Source | aconitase 2, mitochondrial | 3136 | 0.064 | 0.6323 | Yes |
| 13 | DLD | DLD Entrez, Source | dihydrolipoamide dehydrogenase | 3142 | 0.063 | 0.6641 | Yes |
| 14 | IDH3G | IDH3G Entrez, Source | isocitrate dehydrogenase 3 (NAD+) gamma | 3410 | 0.058 | 0.6734 | Yes |
| 15 | CS | CS Entrez, Source | citrate synthase | 4175 | 0.043 | 0.6381 | No |
| 16 | DLST | DLST Entrez, Source | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 4335 | 0.040 | 0.6467 | No |
| 17 | SUCLG1 | SUCLG1 Entrez, Source | succinate-CoA ligase, GDP-forming, alpha subunit | 5738 | 0.018 | 0.5507 | No |
| 18 | SDHC | SDHC Entrez, Source | succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa | 5789 | 0.018 | 0.5559 | No |
| 19 | PCK1 | PCK1 Entrez, Source | phosphoenolpyruvate carboxykinase 1 (soluble) | 6026 | 0.014 | 0.5451 | No |
| 20 | SUCLG2 | SUCLG2 Entrez, Source | succinate-CoA ligase, GDP-forming, beta subunit | 7511 | -0.008 | 0.4377 | No |
