Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | HSA00150_ANDROGEN_AND_ESTROGEN_METABOLISM |
| Enrichment Score (ES) | 0.6103782 |
| Normalized Enrichment Score (NES) | 1.7541952 |
| Nominal p-value | 0.0042735045 |
| FDR q-value | 0.023042452 |
| FWER p-Value | 0.979 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | UGT2A1 | UGT2A1 Entrez, Source | UDP glucuronosyltransferase 2 family, polypeptide A1 | 68 | 0.458 | 0.1735 | Yes |
| 2 | HSD17B7 | HSD17B7 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 7 | 78 | 0.438 | 0.3436 | Yes |
| 3 | HSD11B1 | HSD11B1 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 1 | 370 | 0.242 | 0.4159 | Yes |
| 4 | PRMT3 | PRMT3 Entrez, Source | protein arginine methyltransferase 3 | 498 | 0.203 | 0.4854 | Yes |
| 5 | SRD5A2 | SRD5A2 Entrez, Source | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) | 681 | 0.176 | 0.5401 | Yes |
| 6 | ARSE | ARSE Entrez, Source | arylsulfatase E (chondrodysplasia punctata 1) | 1768 | 0.102 | 0.4983 | Yes |
| 7 | CYP11B1 | CYP11B1 Entrez, Source | cytochrome P450, family 11, subfamily B, polypeptide 1 | 1789 | 0.102 | 0.5364 | Yes |
| 8 | AKR1D1 | AKR1D1 Entrez, Source | aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) | 1859 | 0.099 | 0.5698 | Yes |
| 9 | HSD17B1 | HSD17B1 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 1 | 2175 | 0.089 | 0.5808 | Yes |
| 10 | SRD5A1 | SRD5A1 Entrez, Source | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | 2561 | 0.078 | 0.5822 | Yes |
| 11 | HSD17B2 | HSD17B2 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 2 | 2586 | 0.077 | 0.6104 | Yes |
| 12 | SULT1E1 | SULT1E1 Entrez, Source | sulfotransferase family 1E, estrogen-preferring, member 1 | 3399 | 0.058 | 0.5720 | No |
| 13 | LCMT2 | LCMT2 Entrez, Source | leucine carboxyl methyltransferase 2 | 3734 | 0.051 | 0.5668 | No |
| 14 | HSD11B2 | HSD11B2 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 2 | 4542 | 0.037 | 0.5207 | No |
| 15 | HSD3B1 | HSD3B1 Entrez, Source | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 | 4997 | 0.029 | 0.4980 | No |
| 16 | HSD17B8 | HSD17B8 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 8 | 5000 | 0.029 | 0.5092 | No |
| 17 | HSD17B12 | HSD17B12 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 12 | 5355 | 0.024 | 0.4919 | No |
| 18 | LCMT1 | LCMT1 Entrez, Source | leucine carboxyl methyltransferase 1 | 5536 | 0.021 | 0.4866 | No |
| 19 | CYP19A1 | CYP19A1 Entrez, Source | cytochrome P450, family 19, subfamily A, polypeptide 1 | 6596 | 0.005 | 0.4092 | No |
| 20 | SULT2A1 | SULT2A1 Entrez, Source | sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 | 8105 | -0.016 | 0.3023 | No |
| 21 | HSD17B3 | HSD17B3 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 3 | 8751 | -0.027 | 0.2645 | No |
| 22 | METTL6 | METTL6 Entrez, Source | methyltransferase like 6 | 8832 | -0.029 | 0.2697 | No |
| 23 | CARM1 | CARM1 Entrez, Source | coactivator-associated arginine methyltransferase 1 | 9227 | -0.036 | 0.2542 | No |
| 24 | PRMT2 | PRMT2 Entrez, Source | protein arginine methyltransferase 2 | 9939 | -0.051 | 0.2207 | No |
| 25 | STS | STS Entrez, Source | steroid sulfatase (microsomal), arylsulfatase C, isozyme S | 11277 | -0.089 | 0.1551 | No |
