Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | HSA00330_ARGININE_AND_PROLINE_METABOLISM |
| Enrichment Score (ES) | 0.6541132 |
| Normalized Enrichment Score (NES) | 1.8524482 |
| Nominal p-value | 0.002173913 |
| FDR q-value | 0.010564672 |
| FWER p-Value | 0.689 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | OTC | OTC Entrez, Source | ornithine carbamoyltransferase | 44 | 0.506 | 0.1387 | Yes |
| 2 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 110 | 0.403 | 0.2468 | Yes |
| 3 | ARG1 | ARG1 Entrez, Source | arginase, liver | 145 | 0.358 | 0.3448 | Yes |
| 4 | ASL | ASL Entrez, Source | argininosuccinate lyase | 183 | 0.323 | 0.4328 | Yes |
| 5 | CPS1 | CPS1 Entrez, Source | carbamoyl-phosphate synthetase 1, mitochondrial | 292 | 0.268 | 0.4998 | Yes |
| 6 | GAMT | GAMT Entrez, Source | guanidinoacetate N-methyltransferase | 295 | 0.267 | 0.5747 | Yes |
| 7 | PYCRL | PYCRL Entrez, Source | pyrroline-5-carboxylate reductase-like | 749 | 0.168 | 0.5878 | Yes |
| 8 | OAT | OAT Entrez, Source | ornithine aminotransferase (gyrate atrophy) | 893 | 0.154 | 0.6201 | Yes |
| 9 | EPRS | EPRS Entrez, Source | glutamyl-prolyl-tRNA synthetase | 1177 | 0.132 | 0.6358 | Yes |
| 10 | ASS1 | ASS1 Entrez, Source | argininosuccinate synthetase 1 | 1382 | 0.120 | 0.6541 | Yes |
| 11 | PRODH | PRODH Entrez, Source | proline dehydrogenase (oxidase) 1 | 2331 | 0.084 | 0.6066 | No |
| 12 | NOS1 | NOS1 Entrez, Source | nitric oxide synthase 1 (neuronal) | 2908 | 0.069 | 0.5826 | No |
| 13 | CKMT1A | CKMT1A Entrez, Source | creatine kinase, mitochondrial 1A | 3043 | 0.066 | 0.5909 | No |
| 14 | LAP3 | LAP3 Entrez, Source | leucine aminopeptidase 3 | 3125 | 0.064 | 0.6028 | No |
| 15 | GLUD1 | GLUD1 Entrez, Source | glutamate dehydrogenase 1 | 5087 | 0.028 | 0.4633 | No |
| 16 | GOT2 | GOT2 Entrez, Source | glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) | 5916 | 0.015 | 0.4055 | No |
| 17 | ARG2 | ARG2 Entrez, Source | arginase, type II | 6580 | 0.006 | 0.3573 | No |
| 18 | CKM | CKM Entrez, Source | creatine kinase, muscle | 8557 | -0.024 | 0.2157 | No |
| 19 | CKB | CKB Entrez, Source | creatine kinase, brain | 10604 | -0.067 | 0.0809 | No |
| 20 | PYCR2 | PYCR2 Entrez, Source | pyrroline-5-carboxylate reductase family, member 2 | 11030 | -0.079 | 0.0713 | No |
| 21 | GATM | GATM Entrez, Source | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 11580 | -0.103 | 0.0591 | No |
| 22 | P4HA1 | P4HA1 Entrez, Source | procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide I | 11627 | -0.106 | 0.0853 | No |
| 23 | NOS3 | NOS3 Entrez, Source | nitric oxide synthase 3 (endothelial cell) | 12369 | -0.155 | 0.0730 | No |
