Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | HSA00350_TYROSINE_METABOLISM |
| Enrichment Score (ES) | 0.6399127 |
| Normalized Enrichment Score (NES) | 1.9475789 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0050138813 |
| FWER p-Value | 0.269 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ABP1 | ABP1 Entrez, Source | amiloride binding protein 1 (amine oxidase (copper-containing)) | 24 | 0.594 | 0.1239 | Yes |
| 2 | ADH7 | ADH7 Entrez, Source | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide | 53 | 0.495 | 0.2265 | Yes |
| 3 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 110 | 0.403 | 0.3075 | Yes |
| 4 | HGD | HGD Entrez, Source | homogentisate 1,2-dioxygenase (homogentisate oxidase) | 126 | 0.385 | 0.3880 | Yes |
| 5 | ADHFE1 | ADHFE1 Entrez, Source | alcohol dehydrogenase, iron containing, 1 | 163 | 0.343 | 0.4578 | Yes |
| 6 | AOX1 | AOX1 Entrez, Source | aldehyde oxidase 1 | 201 | 0.309 | 0.5205 | Yes |
| 7 | FAH | FAH Entrez, Source | fumarylacetoacetate hydrolase (fumarylacetoacetase) | 219 | 0.299 | 0.5826 | Yes |
| 8 | PRMT3 | PRMT3 Entrez, Source | protein arginine methyltransferase 3 | 498 | 0.203 | 0.6047 | Yes |
| 9 | TAT | TAT Entrez, Source | tyrosine aminotransferase | 674 | 0.176 | 0.6289 | Yes |
| 10 | ADH1A | ADH1A Entrez, Source | alcohol dehydrogenase 1A (class I), alpha polypeptide | 1116 | 0.136 | 0.6245 | Yes |
| 11 | COMT | COMT Entrez, Source | catechol-O-methyltransferase | 1267 | 0.126 | 0.6399 | Yes |
| 12 | MAOB | MAOB Entrez, Source | monoamine oxidase B | 1779 | 0.102 | 0.6231 | No |
| 13 | ADH6 | ADH6 Entrez, Source | alcohol dehydrogenase 6 (class V) | 2053 | 0.092 | 0.6221 | No |
| 14 | AOC3 | AOC3 Entrez, Source | amine oxidase, copper containing 3 (vascular adhesion protein 1) | 2897 | 0.069 | 0.5734 | No |
| 15 | MAOA | MAOA Entrez, Source | monoamine oxidase A | 3427 | 0.057 | 0.5458 | No |
| 16 | LCMT2 | LCMT2 Entrez, Source | leucine carboxyl methyltransferase 2 | 3734 | 0.051 | 0.5336 | No |
| 17 | PNMT | PNMT Entrez, Source | phenylethanolamine N-methyltransferase | 3761 | 0.051 | 0.5424 | No |
| 18 | ADH4 | ADH4 Entrez, Source | alcohol dehydrogenase 4 (class II), pi polypeptide | 3800 | 0.050 | 0.5501 | No |
| 19 | HPD | HPD Entrez, Source | 4-hydroxyphenylpyruvate dioxygenase | 4383 | 0.040 | 0.5147 | No |
| 20 | TH | TH Entrez, Source | tyrosine hydroxylase | 5089 | 0.028 | 0.4677 | No |
| 21 | MYST3 | MYST3 Entrez, Source | MYST histone acetyltransferase (monocytic leukemia) 3 | 5502 | 0.022 | 0.4413 | No |
| 22 | LCMT1 | LCMT1 Entrez, Source | leucine carboxyl methyltransferase 1 | 5536 | 0.021 | 0.4433 | No |
| 23 | ECH1 | ECH1 Entrez, Source | enoyl Coenzyme A hydratase 1, peroxisomal | 5859 | 0.016 | 0.4226 | No |
| 24 | GOT2 | GOT2 Entrez, Source | glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) | 5916 | 0.015 | 0.4216 | No |
| 25 | DBH | DBH Entrez, Source | dopamine beta-hydroxylase (dopamine beta-monooxygenase) | 8258 | -0.019 | 0.2498 | No |
| 26 | DDC | DDC Entrez, Source | dopa decarboxylase (aromatic L-amino acid decarboxylase) | 8401 | -0.021 | 0.2437 | No |
| 27 | METTL6 | METTL6 Entrez, Source | methyltransferase like 6 | 8832 | -0.029 | 0.2174 | No |
| 28 | CARM1 | CARM1 Entrez, Source | coactivator-associated arginine methyltransferase 1 | 9227 | -0.036 | 0.1955 | No |
| 29 | MIF | MIF Entrez, Source | macrophage migration inhibitory factor (glycosylation-inhibiting factor) | 9316 | -0.038 | 0.1970 | No |
| 30 | ALDH3A1 | ALDH3A1 Entrez, Source | aldehyde dehydrogenase 3 family, memberA1 | 9824 | -0.048 | 0.1691 | No |
| 31 | PRMT2 | PRMT2 Entrez, Source | protein arginine methyltransferase 2 | 9939 | -0.051 | 0.1713 | No |
| 32 | SH3GLB1 | SH3GLB1 Entrez, Source | SH3-domain GRB2-like endophilin B1 | 10950 | -0.077 | 0.1117 | No |
| 33 | TPO | TPO Entrez, Source | thyroid peroxidase | 11532 | -0.101 | 0.0894 | No |
| 34 | ALDH3B1 | ALDH3B1 Entrez, Source | aldehyde dehydrogenase 3 family, member B1 | 12784 | -0.220 | 0.0419 | No |
