Details for gene set HSA00380_TRYPTOPHAN

Table: GSEA Results Summary

Dataset	double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos
Phenotype	class.cls#double_gel_72h_versus_single_gel_72h_repos
Upregulated in class	double_gel_72h
GeneSet	HSA00380_TRYPTOPHAN_METABOLISM
Enrichment Score (ES)	0.72740585
Normalized Enrichment Score (NES)	2.3414273
Nominal p-value	0.0
FDR q-value	0.0
FWER p-Value	0.0

Table: GSEA details [plain text format]
	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	EHHADH	EHHADH Entrez, Source	enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase	6	0.908	0.1367	Yes
2	ABP1	ABP1 Entrez, Source	amiloride binding protein 1 (amine oxidase (copper-containing))	24	0.594	0.2251	Yes
3	KMO	KMO Entrez, Source	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	64	0.478	0.2943	Yes
4	HAAO	HAAO Entrez, Source	3-hydroxyanthranilate 3,4-dioxygenase	120	0.390	0.3492	Yes
5	ACAT2	ACAT2 Entrez, Source	acetyl-Coenzyme A acetyltransferase 2 (acetoacetyl Coenzyme A thiolase)	144	0.362	0.4021	Yes
6	AADAT	AADAT Entrez, Source	aminoadipate aminotransferase	200	0.309	0.4446	Yes
7	AOX1	AOX1 Entrez, Source	aldehyde oxidase 1	201	0.309	0.4913	Yes
8	ACMSD	ACMSD Entrez, Source	aminocarboxymuconate semialdehyde decarboxylase	208	0.306	0.5372	Yes
9	CAT	CAT Entrez, Source	catalase	290	0.269	0.5717	Yes
10	TDO2	TDO2 Entrez, Source	tryptophan 2,3-dioxygenase	358	0.245	0.6037	Yes
11	CYP1A2	CYP1A2 Entrez, Source	cytochrome P450, family 1, subfamily A, polypeptide 2	390	0.235	0.6368	Yes
12	PRMT3	PRMT3 Entrez, Source	protein arginine methyltransferase 3	498	0.203	0.6595	Yes
13	ACAT1	ACAT1 Entrez, Source	acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase)	560	0.191	0.6837	Yes
14	ECHS1	ECHS1 Entrez, Source	enoyl Coenzyme A hydratase, short chain, 1, mitochondrial	633	0.182	0.7057	Yes
15	KYNU	KYNU Entrez, Source	kynureninase (L-kynurenine hydrolase)	695	0.174	0.7274	Yes
16	CYP1B1	CYP1B1 Entrez, Source	cytochrome P450, family 1, subfamily B, polypeptide 1	1078	0.138	0.7196	No
17	HADH	HADH Entrez, Source	hydroxyacyl-Coenzyme A dehydrogenase	1622	0.108	0.6951	No
18	MAOB	MAOB Entrez, Source	monoamine oxidase B	1779	0.102	0.6987	No
19	HADHA	HADHA Entrez, Source	hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit	2174	0.089	0.6825	No
20	AANAT	AANAT Entrez, Source	arylalkylamine N-acetyltransferase	2341	0.084	0.6827	No
21	CYP1A1	CYP1A1 Entrez, Source	cytochrome P450, family 1, subfamily A, polypeptide 1	2351	0.084	0.6947	No
22	HSD17B4	HSD17B4 Entrez, Source	hydroxysteroid (17-beta) dehydrogenase 4	2625	0.076	0.6856	No
23	AOC3	AOC3 Entrez, Source	amine oxidase, copper containing 3 (vascular adhesion protein 1)	2897	0.069	0.6757	No
24	MAOA	MAOA Entrez, Source	monoamine oxidase A	3427	0.057	0.6446	No
25	ALDH7A1	ALDH7A1 Entrez, Source	aldehyde dehydrogenase 7 family, member A1	3614	0.053	0.6386	No
26	NFX1	NFX1 Entrez, Source	nuclear transcription factor, X-box binding 1	3696	0.052	0.6404	No
27	LCMT2	LCMT2 Entrez, Source	leucine carboxyl methyltransferase 2	3734	0.051	0.6453	No
28	TPH1	TPH1 Entrez, Source	tryptophan hydroxylase 1 (tryptophan 5-monooxygenase)	4036	0.046	0.6296	No
29	ALDH3A2	ALDH3A2 Entrez, Source	aldehyde dehydrogenase 3 family, member A2	4819	0.032	0.5757	No
30	ALDH1B1	ALDH1B1 Entrez, Source	aldehyde dehydrogenase 1 family, member B1	5218	0.026	0.5497	No
31	LCMT1	LCMT1 Entrez, Source	leucine carboxyl methyltransferase 1	5536	0.021	0.5291	No
32	ALDH2	ALDH2 Entrez, Source	aldehyde dehydrogenase 2 family (mitochondrial)	6175	0.012	0.4829	No
33	ASMT	ASMT Entrez, Source	acetylserotonin O-methyltransferase	6518	0.006	0.4581	No
34	DDC	DDC Entrez, Source	dopa decarboxylase (aromatic L-amino acid decarboxylase)	8401	-0.021	0.3198	No
35	METTL6	METTL6 Entrez, Source	methyltransferase like 6	8832	-0.029	0.2919	No
36	INDO	INDO Entrez, Source	indoleamine-pyrrole 2,3 dioxygenase	9012	-0.032	0.2833	No
37	CARM1	CARM1 Entrez, Source	coactivator-associated arginine methyltransferase 1	9227	-0.036	0.2727	No
38	ALDH3A1	ALDH3A1 Entrez, Source	aldehyde dehydrogenase 3 family, memberA1	9824	-0.048	0.2352	No
39	PRMT2	PRMT2 Entrez, Source	protein arginine methyltransferase 2	9939	-0.051	0.2343	No
40	ALDH9A1	ALDH9A1 Entrez, Source	aldehyde dehydrogenase 9 family, member A1	10674	-0.069	0.1895	No
41	WARS	WARS Entrez, Source	tryptophanyl-tRNA synthetase	10801	-0.073	0.1910	No