Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | HSA00564_GLYCEROPHOSPHOLIPID_METABOLISM |
| Enrichment Score (ES) | 0.4716936 |
| Normalized Enrichment Score (NES) | 1.49577 |
| Nominal p-value | 0.018735362 |
| FDR q-value | 0.123314455 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PEMT | PEMT Entrez, Source | phosphatidylethanolamine N-methyltransferase | 8 | 0.798 | 0.1870 | Yes |
| 2 | LCAT | LCAT Entrez, Source | lecithin-cholesterol acyltransferase | 142 | 0.365 | 0.2629 | Yes |
| 3 | GPD1 | GPD1 Entrez, Source | glycerol-3-phosphate dehydrogenase 1 (soluble) | 296 | 0.267 | 0.3142 | Yes |
| 4 | PPAP2B | PPAP2B Entrez, Source | phosphatidic acid phosphatase type 2B | 329 | 0.257 | 0.3723 | Yes |
| 5 | DGKI | DGKI Entrez, Source | diacylglycerol kinase, iota | 697 | 0.174 | 0.3856 | Yes |
| 6 | CHPT1 | CHPT1 Entrez, Source | choline phosphotransferase 1 | 778 | 0.165 | 0.4182 | Yes |
| 7 | GPAM | GPAM Entrez, Source | glycerol-3-phosphate acyltransferase, mitochondrial | 954 | 0.149 | 0.4400 | Yes |
| 8 | DGKZ | DGKZ Entrez, Source | diacylglycerol kinase, zeta 104kDa | 990 | 0.146 | 0.4717 | Yes |
| 9 | PLA2G2D | PLA2G2D Entrez, Source | phospholipase A2, group IID | 1734 | 0.104 | 0.4402 | No |
| 10 | CHKA | CHKA Entrez, Source | choline kinase alpha | 2612 | 0.076 | 0.3922 | No |
| 11 | PLA2G6 | PLA2G6 Entrez, Source | phospholipase A2, group VI (cytosolic, calcium-independent) | 2615 | 0.076 | 0.4098 | No |
| 12 | CDS1 | CDS1 Entrez, Source | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 | 2733 | 0.073 | 0.4182 | No |
| 13 | PLA2G5 | PLA2G5 Entrez, Source | phospholipase A2, group V | 3301 | 0.060 | 0.3896 | No |
| 14 | GNPAT | GNPAT Entrez, Source | glyceronephosphate O-acyltransferase | 3398 | 0.058 | 0.3961 | No |
| 15 | AGPAT1 | AGPAT1 Entrez, Source | 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) | 4028 | 0.046 | 0.3596 | No |
| 16 | CHKB | CHKB Entrez, Source | choline kinase beta | 4787 | 0.033 | 0.3103 | No |
| 17 | MYST3 | MYST3 Entrez, Source | MYST histone acetyltransferase (monocytic leukemia) 3 | 5502 | 0.022 | 0.2618 | No |
| 18 | PCYT1B | PCYT1B Entrez, Source | phosphate cytidylyltransferase 1, choline, beta | 6186 | 0.012 | 0.2131 | No |
| 19 | GPD2 | GPD2 Entrez, Source | glycerol-3-phosphate dehydrogenase 2 (mitochondrial) | 6237 | 0.011 | 0.2119 | No |
| 20 | PCYT1A | PCYT1A Entrez, Source | phosphate cytidylyltransferase 1, choline, alpha | 7554 | -0.008 | 0.1149 | No |
| 21 | PTDSS1 | PTDSS1 Entrez, Source | phosphatidylserine synthase 1 | 7804 | -0.012 | 0.0990 | No |
| 22 | PLD1 | PLD1 Entrez, Source | phospholipase D1, phosphatidylcholine-specific | 7809 | -0.012 | 0.1016 | No |
| 23 | PLA2G10 | PLA2G10 Entrez, Source | phospholipase A2, group X | 7884 | -0.013 | 0.0992 | No |
| 24 | DGKG | DGKG Entrez, Source | diacylglycerol kinase, gamma 90kDa | 7914 | -0.014 | 0.1003 | No |
| 25 | DGKB | DGKB Entrez, Source | diacylglycerol kinase, beta 90kDa | 7974 | -0.015 | 0.0993 | No |
| 26 | PPAP2C | PPAP2C Entrez, Source | phosphatidic acid phosphatase type 2C | 8161 | -0.017 | 0.0893 | No |
| 27 | PPAP2A | PPAP2A Entrez, Source | phosphatidic acid phosphatase type 2A | 8226 | -0.018 | 0.0888 | No |
| 28 | PLA2G1B | PLA2G1B Entrez, Source | phospholipase A2, group IB (pancreas) | 8831 | -0.029 | 0.0502 | No |
| 29 | CDS2 | CDS2 Entrez, Source | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 | 8879 | -0.029 | 0.0536 | No |
| 30 | LYPLA2 | LYPLA2 Entrez, Source | lysophospholipase II | 9600 | -0.043 | 0.0096 | No |
| 31 | LYPLA1 | LYPLA1 Entrez, Source | lysophospholipase I | 10038 | -0.053 | -0.0108 | No |
| 32 | PLD2 | PLD2 Entrez, Source | phospholipase D2 | 10232 | -0.058 | -0.0118 | No |
| 33 | AGPAT4 | AGPAT4 Entrez, Source | 1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta) | 10343 | -0.060 | -0.0059 | No |
| 34 | CDIPT | CDIPT Entrez, Source | CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase) | 10845 | -0.074 | -0.0262 | No |
| 35 | SH3GLB1 | SH3GLB1 Entrez, Source | SH3-domain GRB2-like endophilin B1 | 10950 | -0.077 | -0.0160 | No |
| 36 | PLA2G2A | PLA2G2A Entrez, Source | phospholipase A2, group IIA (platelets, synovial fluid) | 11878 | -0.118 | -0.0579 | No |
| 37 | DGKA | DGKA Entrez, Source | diacylglycerol kinase, alpha 80kDa | 12191 | -0.138 | -0.0488 | No |
| 38 | AGPAT6 | AGPAT6 Entrez, Source | 1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta) | 12308 | -0.149 | -0.0225 | No |
| 39 | PLA2G4A | PLA2G4A Entrez, Source | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 12414 | -0.160 | 0.0071 | No |
| 40 | LYPLA3 | LYPLA3 Entrez, Source | lysophospholipase 3 (lysosomal phospholipase A2) | 12939 | -0.266 | 0.0303 | No |
