Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | HSA01430_CELL_COMMUNICATION |
| Enrichment Score (ES) | -0.6024219 |
| Normalized Enrichment Score (NES) | -1.8637938 |
| Nominal p-value | 0.0017123288 |
| FDR q-value | 0.02765124 |
| FWER p-Value | 0.756 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GJB2 | GJB2 Entrez, Source | gap junction protein, beta 2, 26kDa (connexin 26) | 115 | 0.397 | 0.0405 | No |
| 2 | COL5A3 | COL5A3 Entrez, Source | collagen, type V, alpha 3 | 224 | 0.297 | 0.0691 | No |
| 3 | VTN | VTN Entrez, Source | vitronectin | 349 | 0.249 | 0.0906 | No |
| 4 | KRT25 | KRT25 Entrez, Source | keratin 25 | 821 | 0.160 | 0.0750 | No |
| 5 | LAMA3 | LAMA3 Entrez, Source | laminin, alpha 3 | 1001 | 0.144 | 0.0794 | No |
| 6 | GJB1 | GJB1 Entrez, Source | gap junction protein, beta 1, 32kDa (connexin 32, Charcot-Marie-Tooth neuropathy, X-linked) | 1293 | 0.124 | 0.0729 | No |
| 7 | TNR | TNR Entrez, Source | tenascin R (restrictin, janusin) | 1431 | 0.117 | 0.0770 | No |
| 8 | COL1A1 | COL1A1 Entrez, Source | collagen, type I, alpha 1 | 1619 | 0.108 | 0.0763 | No |
| 9 | COL6A2 | COL6A2 Entrez, Source | collagen, type VI, alpha 2 | 2971 | 0.067 | -0.0170 | No |
| 10 | DSC2 | DSC2 Entrez, Source | desmocollin 2 | 2983 | 0.067 | -0.0096 | No |
| 11 | SPP1 | SPP1 Entrez, Source | secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) | 4327 | 0.041 | -0.1056 | No |
| 12 | GJA3 | GJA3 Entrez, Source | gap junction protein, alpha 3, 46kDa (connexin 46) | 4332 | 0.041 | -0.1008 | No |
| 13 | COL4A4 | COL4A4 Entrez, Source | collagen, type IV, alpha 4 | 4358 | 0.040 | -0.0978 | No |
| 14 | GJB6 | GJB6 Entrez, Source | gap junction protein, beta 6 (connexin 30) | 4808 | 0.032 | -0.1276 | No |
| 15 | COL2A1 | COL2A1 Entrez, Source | collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital) | 5191 | 0.026 | -0.1530 | No |
| 16 | GJA5 | GJA5 Entrez, Source | gap junction protein, alpha 5, 40kDa (connexin 40) | 5462 | 0.022 | -0.1706 | No |
| 17 | GJA1 | GJA1 Entrez, Source | gap junction protein, alpha 1, 43kDa (connexin 43) | 6120 | 0.013 | -0.2184 | No |
| 18 | THBS2 | THBS2 Entrez, Source | thrombospondin 2 | 6709 | 0.004 | -0.2622 | No |
| 19 | IBSP | IBSP Entrez, Source | integrin-binding sialoprotein (bone sialoprotein, bone sialoprotein II) | 6712 | 0.004 | -0.2619 | No |
| 20 | THBS4 | THBS4 Entrez, Source | thrombospondin 4 | 6884 | 0.002 | -0.2746 | No |
| 21 | GJB4 | GJB4 Entrez, Source | gap junction protein, beta 4 (connexin 30.3) | 6944 | 0.000 | -0.2790 | No |
| 22 | COL5A1 | COL5A1 Entrez, Source | collagen, type V, alpha 1 | 7132 | -0.002 | -0.2928 | No |
| 23 | VWF | VWF Entrez, Source | von Willebrand factor | 7187 | -0.003 | -0.2965 | No |
| 24 | GJA4 | GJA4 Entrez, Source | gap junction protein, alpha 4, 37kDa (connexin 37) | 7260 | -0.004 | -0.3014 | No |
| 25 | COL1A2 | COL1A2 Entrez, Source | collagen, type I, alpha 2 | 8051 | -0.016 | -0.3589 | No |
| 26 | COL11A1 | COL11A1 Entrez, Source | collagen, type XI, alpha 1 | 8104 | -0.016 | -0.3608 | No |
| 27 | CHAD | CHAD Entrez, Source | chondroadherin | 9871 | -0.049 | -0.4875 | No |
| 28 | FN1 | FN1 Entrez, Source | fibronectin 1 | 10062 | -0.053 | -0.4953 | No |
| 29 | DES | DES Entrez, Source | desmin | 11462 | -0.098 | -0.5884 | Yes |
| 30 | ACTB | ACTB Entrez, Source | actin, beta | 11552 | -0.102 | -0.5824 | Yes |
| 31 | COMP | COMP Entrez, Source | cartilage oligomeric matrix protein | 11817 | -0.115 | -0.5881 | Yes |
| 32 | COL5A2 | COL5A2 Entrez, Source | collagen, type V, alpha 2 | 12008 | -0.126 | -0.5869 | Yes |
| 33 | LMNA | LMNA Entrez, Source | lamin A/C | 12083 | -0.130 | -0.5763 | Yes |
| 34 | ITGB4 | ITGB4 Entrez, Source | integrin, beta 4 | 12348 | -0.153 | -0.5773 | Yes |
| 35 | GJB3 | GJB3 Entrez, Source | gap junction protein, beta 3, 31kDa (connexin 31) | 12502 | -0.171 | -0.5677 | Yes |
| 36 | COL3A1 | COL3A1 Entrez, Source | collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) | 12541 | -0.177 | -0.5486 | Yes |
| 37 | LAMA5 | LAMA5 Entrez, Source | laminin, alpha 5 | 12592 | -0.184 | -0.5296 | Yes |
| 38 | KRT20 | KRT20 Entrez, Source | keratin 20 | 12610 | -0.186 | -0.5079 | Yes |
| 39 | ITGA6 | ITGA6 Entrez, Source | integrin, alpha 6 | 12855 | -0.239 | -0.4968 | Yes |
| 40 | COL4A1 | COL4A1 Entrez, Source | collagen, type IV, alpha 1 | 12937 | -0.264 | -0.4701 | Yes |
| 41 | RELN | RELN Entrez, Source | reelin | 12968 | -0.279 | -0.4379 | Yes |
| 42 | GJB5 | GJB5 Entrez, Source | gap junction protein, beta 5 (connexin 31.1) | 13002 | -0.292 | -0.4043 | Yes |
| 43 | LAMC1 | LAMC1 Entrez, Source | laminin, gamma 1 (formerly LAMB2) | 13018 | -0.300 | -0.3684 | Yes |
| 44 | LMNB1 | LMNB1 Entrez, Source | lamin B1 | 13086 | -0.343 | -0.3310 | Yes |
| 45 | LAMB3 | LAMB3 Entrez, Source | laminin, beta 3 | 13195 | -0.458 | -0.2824 | Yes |
| 46 | VIM | VIM Entrez, Source | vimentin | 13227 | -0.506 | -0.2221 | Yes |
| 47 | NES | NES Entrez, Source | nestin | 13241 | -0.529 | -0.1577 | Yes |
| 48 | LAMC2 | LAMC2 Entrez, Source | laminin, gamma 2 | 13264 | -0.594 | -0.0858 | Yes |
| 49 | LAMB2 | LAMB2 Entrez, Source | laminin, beta 2 (laminin S) | 13299 | -0.740 | 0.0032 | Yes |
