Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | HSA04512_ECM_RECEPTOR_INTERACTION |
| Enrichment Score (ES) | -0.56024754 |
| Normalized Enrichment Score (NES) | -1.7481827 |
| Nominal p-value | 0.0017921147 |
| FDR q-value | 0.04756226 |
| FWER p-Value | 0.999 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | COL5A3 | COL5A3 Entrez, Source | collagen, type V, alpha 3 | 224 | 0.297 | 0.0254 | No |
| 2 | VTN | VTN Entrez, Source | vitronectin | 349 | 0.249 | 0.0514 | No |
| 3 | SV2B | SV2B Entrez, Source | synaptic vesicle glycoprotein 2B | 814 | 0.161 | 0.0394 | No |
| 4 | SDC2 | SDC2 Entrez, Source | syndecan 2 (heparan sulfate proteoglycan 1, cell surface-associated, fibroglycan) | 817 | 0.161 | 0.0621 | No |
| 5 | LAMA3 | LAMA3 Entrez, Source | laminin, alpha 3 | 1001 | 0.144 | 0.0688 | No |
| 6 | TNR | TNR Entrez, Source | tenascin R (restrictin, janusin) | 1431 | 0.117 | 0.0531 | No |
| 7 | COL1A1 | COL1A1 Entrez, Source | collagen, type I, alpha 1 | 1619 | 0.108 | 0.0544 | No |
| 8 | ITGA7 | ITGA7 Entrez, Source | integrin, alpha 7 | 2929 | 0.068 | -0.0344 | No |
| 9 | FNDC5 | FNDC5 Entrez, Source | fibronectin type III domain containing 5 | 2938 | 0.068 | -0.0253 | No |
| 10 | COL6A2 | COL6A2 Entrez, Source | collagen, type VI, alpha 2 | 2971 | 0.067 | -0.0182 | No |
| 11 | SDC4 | SDC4 Entrez, Source | syndecan 4 (amphiglycan, ryudocan) | 3350 | 0.059 | -0.0382 | No |
| 12 | SPP1 | SPP1 Entrez, Source | secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) | 4327 | 0.041 | -0.1059 | No |
| 13 | COL4A4 | COL4A4 Entrez, Source | collagen, type IV, alpha 4 | 4358 | 0.040 | -0.1024 | No |
| 14 | SV2C | SV2C Entrez, Source | synaptic vesicle glycoprotein 2C | 4562 | 0.037 | -0.1125 | No |
| 15 | GP9 | GP9 Entrez, Source | glycoprotein IX (platelet) | 4615 | 0.036 | -0.1113 | No |
| 16 | SDC3 | SDC3 Entrez, Source | syndecan 3 (N-syndecan) | 4748 | 0.034 | -0.1164 | No |
| 17 | COL2A1 | COL2A1 Entrez, Source | collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital) | 5191 | 0.026 | -0.1459 | No |
| 18 | ITGA1 | ITGA1 Entrez, Source | integrin, alpha 1 | 5518 | 0.021 | -0.1674 | No |
| 19 | SV2A | SV2A Entrez, Source | synaptic vesicle glycoprotein 2A | 6094 | 0.013 | -0.2088 | No |
| 20 | GP5 | GP5 Entrez, Source | glycoprotein V (platelet) | 6523 | 0.006 | -0.2402 | No |
| 21 | THBS2 | THBS2 Entrez, Source | thrombospondin 2 | 6709 | 0.004 | -0.2536 | No |
| 22 | IBSP | IBSP Entrez, Source | integrin-binding sialoprotein (bone sialoprotein, bone sialoprotein II) | 6712 | 0.004 | -0.2532 | No |
| 23 | THBS4 | THBS4 Entrez, Source | thrombospondin 4 | 6884 | 0.002 | -0.2658 | No |
| 24 | COL5A1 | COL5A1 Entrez, Source | collagen, type V, alpha 1 | 7132 | -0.002 | -0.2841 | No |
| 25 | VWF | VWF Entrez, Source | von Willebrand factor | 7187 | -0.003 | -0.2878 | No |
| 26 | COL1A2 | COL1A2 Entrez, Source | collagen, type I, alpha 2 | 8051 | -0.016 | -0.3505 | No |
| 27 | COL11A1 | COL11A1 Entrez, Source | collagen, type XI, alpha 1 | 8104 | -0.016 | -0.3521 | No |
| 28 | ITGB5 | ITGB5 Entrez, Source | integrin, beta 5 | 8308 | -0.020 | -0.3645 | No |
| 29 | CHAD | CHAD Entrez, Source | chondroadherin | 9871 | -0.049 | -0.4750 | No |
| 30 | FN1 | FN1 Entrez, Source | fibronectin 1 | 10062 | -0.053 | -0.4818 | No |
| 31 | ITGB7 | ITGB7 Entrez, Source | integrin, beta 7 | 10842 | -0.074 | -0.5299 | No |
| 32 | FNDC1 | FNDC1 Entrez, Source | fibronectin type III domain containing 1 | 11008 | -0.079 | -0.5311 | No |
| 33 | ITGB1 | ITGB1 Entrez, Source | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 11396 | -0.095 | -0.5468 | Yes |
| 34 | SDC1 | SDC1 Entrez, Source | syndecan 1 | 11411 | -0.095 | -0.5343 | Yes |
| 35 | ITGB6 | ITGB6 Entrez, Source | integrin, beta 6 | 11708 | -0.110 | -0.5410 | Yes |
| 36 | ITGA9 | ITGA9 Entrez, Source | integrin, alpha 9 | 11796 | -0.113 | -0.5314 | Yes |
| 37 | DAG1 | DAG1 Entrez, Source | dystroglycan 1 (dystrophin-associated glycoprotein 1) | 11814 | -0.114 | -0.5165 | Yes |
| 38 | COL5A2 | COL5A2 Entrez, Source | collagen, type V, alpha 2 | 12008 | -0.126 | -0.5131 | Yes |
| 39 | ITGB4 | ITGB4 Entrez, Source | integrin, beta 4 | 12348 | -0.153 | -0.5169 | Yes |
| 40 | COL3A1 | COL3A1 Entrez, Source | collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) | 12541 | -0.177 | -0.5061 | Yes |
| 41 | LAMA5 | LAMA5 Entrez, Source | laminin, alpha 5 | 12592 | -0.184 | -0.4838 | Yes |
| 42 | CD47 | CD47 Entrez, Source | CD47 molecule | 12700 | -0.205 | -0.4627 | Yes |
| 43 | ITGA6 | ITGA6 Entrez, Source | integrin, alpha 6 | 12855 | -0.239 | -0.4404 | Yes |
| 44 | COL4A1 | COL4A1 Entrez, Source | collagen, type IV, alpha 1 | 12937 | -0.264 | -0.4089 | Yes |
| 45 | RELN | RELN Entrez, Source | reelin | 12968 | -0.279 | -0.3716 | Yes |
| 46 | HMMR | HMMR Entrez, Source | hyaluronan-mediated motility receptor (RHAMM) | 12987 | -0.285 | -0.3324 | Yes |
| 47 | LAMC1 | LAMC1 Entrez, Source | laminin, gamma 1 (formerly LAMB2) | 13018 | -0.300 | -0.2921 | Yes |
| 48 | CD44 | CD44 Entrez, Source | CD44 molecule (Indian blood group) | 13174 | -0.431 | -0.2424 | Yes |
| 49 | LAMB3 | LAMB3 Entrez, Source | laminin, beta 3 | 13195 | -0.458 | -0.1788 | Yes |
| 50 | LAMC2 | LAMC2 Entrez, Source | laminin, gamma 2 | 13264 | -0.594 | -0.0995 | Yes |
| 51 | LAMB2 | LAMB2 Entrez, Source | laminin, beta 2 (laminin S) | 13299 | -0.740 | 0.0032 | Yes |
