Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | HSA04520_ADHERENS_JUNCTION |
| Enrichment Score (ES) | -0.57543707 |
| Normalized Enrichment Score (NES) | -1.754456 |
| Nominal p-value | 0.003552398 |
| FDR q-value | 0.046412673 |
| FWER p-Value | 0.999 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PTPN6 | PTPN6 Entrez, Source | protein tyrosine phosphatase, non-receptor type 6 | 716 | 0.171 | -0.0229 | No |
| 2 | INSR | INSR Entrez, Source | insulin receptor | 735 | 0.169 | 0.0062 | No |
| 3 | PTPRM | PTPRM Entrez, Source | protein tyrosine phosphatase, receptor type, M | 2639 | 0.075 | -0.1233 | No |
| 4 | IGF1R | IGF1R Entrez, Source | insulin-like growth factor 1 receptor | 3241 | 0.061 | -0.1575 | No |
| 5 | FYN | FYN Entrez, Source | FYN oncogene related to SRC, FGR, YES | 3374 | 0.059 | -0.1568 | No |
| 6 | RAC2 | RAC2 Entrez, Source | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) | 3781 | 0.050 | -0.1783 | No |
| 7 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 4079 | 0.045 | -0.1925 | No |
| 8 | ACP1 | ACP1 Entrez, Source | acid phosphatase 1, soluble | 4108 | 0.044 | -0.1866 | No |
| 9 | LEF1 | LEF1 Entrez, Source | lymphoid enhancer-binding factor 1 | 4161 | 0.044 | -0.1826 | No |
| 10 | CSNK2B | CSNK2B Entrez, Source | casein kinase 2, beta polypeptide | 4466 | 0.038 | -0.1986 | No |
| 11 | WASL | WASL Entrez, Source | Wiskott-Aldrich syndrome-like | 4951 | 0.030 | -0.2296 | No |
| 12 | CDH1 | CDH1 Entrez, Source | cadherin 1, type 1, E-cadherin (epithelial) | 5315 | 0.024 | -0.2525 | No |
| 13 | FGFR1 | FGFR1 Entrez, Source | fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) | 6041 | 0.014 | -0.3046 | No |
| 14 | CTNNB1 | CTNNB1 Entrez, Source | catenin (cadherin-associated protein), beta 1, 88kDa | 8312 | -0.020 | -0.4717 | No |
| 15 | CREBBP | CREBBP Entrez, Source | CREB binding protein (Rubinstein-Taybi syndrome) | 8561 | -0.024 | -0.4860 | No |
| 16 | CSNK2A1 | CSNK2A1 Entrez, Source | casein kinase 2, alpha 1 polypeptide | 8665 | -0.026 | -0.4891 | No |
| 17 | SSX2IP | SSX2IP Entrez, Source | synovial sarcoma, X breakpoint 2 interacting protein | 8915 | -0.030 | -0.5023 | No |
| 18 | SNAI1 | SNAI1 Entrez, Source | snail homolog 1 (Drosophila) | 9442 | -0.040 | -0.5345 | No |
| 19 | SMAD3 | SMAD3 Entrez, Source | SMAD, mothers against DPP homolog 3 (Drosophila) | 9459 | -0.041 | -0.5284 | No |
| 20 | CDC42 | CDC42 Entrez, Source | cell division cycle 42 (GTP binding protein, 25kDa) | 9556 | -0.043 | -0.5279 | No |
| 21 | MAPK1 | MAPK1 Entrez, Source | mitogen-activated protein kinase 1 | 9755 | -0.047 | -0.5343 | No |
| 22 | PVRL1 | PVRL1 Entrez, Source | poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin) | 9846 | -0.049 | -0.5323 | No |
| 23 | TGFBR1 | TGFBR1 Entrez, Source | transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa) | 9978 | -0.052 | -0.5328 | No |
| 24 | ACVR1C | ACVR1C Entrez, Source | activin A receptor, type IC | 10060 | -0.053 | -0.5293 | No |
| 25 | PARD3 | PARD3 Entrez, Source | par-3 partitioning defective 3 homolog (C. elegans) | 10642 | -0.068 | -0.5607 | Yes |
| 26 | RAC1 | RAC1 Entrez, Source | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 10733 | -0.071 | -0.5547 | Yes |
| 27 | EP300 | EP300 Entrez, Source | E1A binding protein p300 | 11002 | -0.079 | -0.5606 | Yes |
| 28 | SMAD4 | SMAD4 Entrez, Source | SMAD, mothers against DPP homolog 4 (Drosophila) | 11091 | -0.082 | -0.5525 | Yes |
| 29 | MLLT4 | MLLT4 Entrez, Source | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 | 11397 | -0.095 | -0.5583 | Yes |
| 30 | RHOA | RHOA Entrez, Source | ras homolog gene family, member A | 11466 | -0.098 | -0.5457 | Yes |
| 31 | SRC | SRC Entrez, Source | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 11494 | -0.099 | -0.5298 | Yes |
| 32 | ACTB | ACTB Entrez, Source | actin, beta | 11552 | -0.102 | -0.5157 | Yes |
| 33 | SMAD2 | SMAD2 Entrez, Source | SMAD, mothers against DPP homolog 2 (Drosophila) | 11923 | -0.120 | -0.5219 | Yes |
| 34 | ACTN3 | ACTN3 Entrez, Source | actinin, alpha 3 | 11968 | -0.123 | -0.5030 | Yes |
| 35 | BAIAP2 | BAIAP2 Entrez, Source | BAI1-associated protein 2 | 11997 | -0.125 | -0.4826 | Yes |
| 36 | PTPRF | PTPRF Entrez, Source | protein tyrosine phosphatase, receptor type, F | 12127 | -0.133 | -0.4683 | Yes |
| 37 | ERBB2 | ERBB2 Entrez, Source | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 12233 | -0.142 | -0.4505 | Yes |
| 38 | PTPN1 | PTPN1 Entrez, Source | protein tyrosine phosphatase, non-receptor type 1 | 12267 | -0.145 | -0.4267 | Yes |
| 39 | MAPK3 | MAPK3 Entrez, Source | mitogen-activated protein kinase 3 | 12441 | -0.162 | -0.4104 | Yes |
| 40 | MET | MET Entrez, Source | met proto-oncogene (hepatocyte growth factor receptor) | 12449 | -0.164 | -0.3813 | Yes |
| 41 | PTPRJ | PTPRJ Entrez, Source | protein tyrosine phosphatase, receptor type, J | 12463 | -0.165 | -0.3525 | Yes |
| 42 | TGFBR2 | TGFBR2 Entrez, Source | transforming growth factor, beta receptor II (70/80kDa) | 12582 | -0.181 | -0.3286 | Yes |
| 43 | WASF1 | WASF1 Entrez, Source | WAS protein family, member 1 | 12675 | -0.199 | -0.2995 | Yes |
| 44 | WASF2 | WASF2 Entrez, Source | WAS protein family, member 2 | 12803 | -0.226 | -0.2683 | Yes |
| 45 | ACTN4 | ACTN4 Entrez, Source | actinin, alpha 4 | 12871 | -0.243 | -0.2295 | Yes |
| 46 | PVRL2 | PVRL2 Entrez, Source | poliovirus receptor-related 2 (herpesvirus entry mediator B) | 13071 | -0.333 | -0.1842 | Yes |
| 47 | LMO7 | LMO7 Entrez, Source | LIM domain 7 | 13209 | -0.477 | -0.1084 | Yes |
| 48 | ACTN1 | ACTN1 Entrez, Source | actinin, alpha 1 | 13279 | -0.655 | 0.0047 | Yes |
