Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_72h_versus_single_gel_72h.class.cls
#double_gel_72h_versus_single_gel_72h_repos
Phenotypeclass.cls#double_gel_72h_versus_single_gel_72h_repos
Upregulated in classdouble_gel_72h
GeneSetHUMAN_MITODB_6_2002
Enrichment Score (ES)0.43645862
Normalized Enrichment Score (NES)1.886281
Nominal p-value0.0
FDR q-value0.007695762
FWER p-Value0.533
Table: GSEA Results Summary



Fig 1: Enrichment plot: HUMAN_MITODB_6_2002   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1GLYATGLYAT
Entrez,  Source
glycine-N-acyltransferase330.5540.0197Yes
2OTCOTC
Entrez,  Source
ornithine carbamoyltransferase440.5060.0391Yes
3BCL2A1BCL2A1
Entrez,  Source
BCL2-related protein A1670.4590.0558Yes
4GOT1GOT1
Entrez,  Source
glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)1100.4030.0687Yes
5HMGCS2HMGCS2
Entrez,  Source
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial)1170.3960.0841Yes
6AGXTAGXT
Entrez,  Source
alanine-glyoxylate aminotransferase (oxalosis I; hyperoxaluria I; glycolicaciduria; serine-pyruvate aminotransferase)1280.3840.0987Yes
7ACAA2ACAA2
Entrez,  Source
acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase)1350.3740.1132Yes
8GCKGCK
Entrez,  Source
glucokinase (hexokinase 4, maturity onset diabetes of the young 2)1400.3680.1277Yes
9PCPC
Entrez,  Source
pyruvate carboxylase1550.3470.1405Yes
10ABATABAT
Entrez,  Source
4-aminobutyrate aminotransferase1850.3210.1511Yes
11CPT2CPT2
Entrez,  Source
carnitine palmitoyltransferase II2070.3070.1618Yes
12SARDHSARDH
Entrez,  Source
sarcosine dehydrogenase2370.2910.1712Yes
13CPS1CPS1
Entrez,  Source
carbamoyl-phosphate synthetase 1, mitochondrial2920.2680.1778Yes
14CLPXCLPX
Entrez,  Source
ClpX caseinolytic peptidase X homolog (E. coli)3740.2410.1813Yes
15SLC25A10SLC25A10
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 103780.2400.1906Yes
16TSTTST
Entrez,  Source
thiosulfate sulfurtransferase (rhodanese)3880.2350.1994Yes
17MTHFD1MTHFD1
Entrez,  Source
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase4050.2290.2073Yes
18PDK4PDK4
Entrez,  Source
pyruvate dehydrogenase kinase, isozyme 44120.2270.2159Yes
19ALAS1ALAS1
Entrez,  Source
aminolevulinate, delta-, synthase 14190.2240.2245Yes
20TIMM8ATIMM8A
Entrez,  Source
translocase of inner mitochondrial membrane 8 homolog A (yeast)4250.2230.2330Yes
21TIMM9TIMM9
Entrez,  Source
translocase of inner mitochondrial membrane 9 homolog (yeast)4630.2120.2387Yes
22ACADVLACADVL
Entrez,  Source
acyl-Coenzyme A dehydrogenase, very long chain4820.2070.2456Yes
23BCS1LBCS1L
Entrez,  Source
BCS1-like (yeast)5040.2010.2520Yes
24MCCC1MCCC1
Entrez,  Source
methylcrotonoyl-Coenzyme A carboxylase 1 (alpha)5560.1920.2558Yes
25ACAT1ACAT1
Entrez,  Source
acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase)5600.1910.2632Yes
26ATP5G1ATP5G1
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9)5610.1910.2708Yes
27PDHBPDHB
Entrez,  Source
pyruvate dehydrogenase (lipoamide) beta5630.1900.2784Yes
28SLC25A15SLC25A15
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 155950.1860.2835Yes
29ETFDHETFDH
Entrez,  Source
electron-transferring-flavoprotein dehydrogenase6030.1860.2904Yes
30ECHS1ECHS1
Entrez,  Source
enoyl Coenzyme A hydratase, short chain, 1, mitochondrial6330.1820.2954Yes
31BCKDHBBCKDHB
Entrez,  Source
branched chain keto acid dehydrogenase E1, beta polypeptide (maple syrup urine disease)6510.1790.3013Yes
32BCKDHABCKDHA
Entrez,  Source
branched chain keto acid dehydrogenase E1, alpha polypeptide6620.1780.3076Yes
33PDK1PDK1
Entrez,  Source
pyruvate dehydrogenase kinase, isozyme 16730.1760.3139Yes
34TATTAT
Entrez,  Source
tyrosine aminotransferase6740.1760.3210Yes
35SOD2SOD2
Entrez,  Source
superoxide dismutase 2, mitochondrial6780.1760.3278Yes
36HMGCLHMGCL
Entrez,  Source
3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (hydroxymethylglutaricaciduria)7320.1690.3305Yes
37CRY1CRY1
Entrez,  Source
cryptochrome 1 (photolyase-like)7340.1690.3372Yes
38MRPL46MRPL46
Entrez,  Source
mitochondrial ribosomal protein L467430.1680.3433Yes
39ETFBETFB
Entrez,  Source
electron-transfer-flavoprotein, beta polypeptide7460.1680.3498Yes
40SLC25A20SLC25A20
Entrez,  Source
solute carrier family 25 (carnitine/acylcarnitine translocase), member 208420.1580.3489Yes
41BCKDKBCKDK
Entrez,  Source
branched chain ketoacid dehydrogenase kinase8680.1560.3533Yes
42NDUFV2NDUFV2
Entrez,  Source
NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa8890.1540.3579Yes
43OATOAT
Entrez,  Source
ornithine aminotransferase (gyrate atrophy)8930.1540.3638Yes
44MRPS15MRPS15
Entrez,  Source
mitochondrial ribosomal protein S159360.1500.3666Yes
45SHMT1SHMT1
Entrez,  Source
serine hydroxymethyltransferase 1 (soluble)9390.1500.3724Yes
46TFB1MTFB1M
Entrez,  Source
transcription factor B1, mitochondrial9470.1490.3778Yes
47TIMM10TIMM10
Entrez,  Source
translocase of inner mitochondrial membrane 10 homolog (yeast)10210.1430.3780Yes
48CA5ACA5A
Entrez,  Source
carbonic anhydrase VA, mitochondrial10340.1420.3827Yes
49CPT1ACPT1A
Entrez,  Source
carnitine palmitoyltransferase 1A (liver)10460.1400.3875Yes
50GCATGCAT
Entrez,  Source
glycine C-acetyltransferase (2-amino-3-ketobutyrate coenzyme A ligase)11350.1350.3862Yes
51AMACRAMACR
Entrez,  Source
alpha-methylacyl-CoA racemase11430.1340.3910Yes
52AFG3L2AFG3L2
Entrez,  Source
AFG3 ATPase family gene 3-like 2 (yeast)12420.1270.3886Yes
53SHMT2SHMT2
Entrez,  Source
serine hydroxymethyltransferase 2 (mitochondrial)13470.1220.3856Yes
54ATP5OATP5O
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein)13600.1210.3895Yes
55NDUFS7NDUFS7
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)13710.1210.3935Yes
56AMTAMT
Entrez,  Source
aminomethyltransferase13970.1190.3964Yes
57TXN2TXN2
Entrez,  Source
thioredoxin 214540.1160.3967Yes
58MIPEPMIPEP
Entrez,  Source
mitochondrial intermediate peptidase14550.1160.4014Yes
59ACADSBACADSB
Entrez,  Source
acyl-Coenzyme A dehydrogenase, short/branched chain14800.1140.4041Yes
60DECR1DECR1
Entrez,  Source
2,4-dienoyl CoA reductase 1, mitochondrial15880.1090.4003Yes
61SCP2SCP2
Entrez,  Source
sterol carrier protein 216320.1070.4013Yes
62MRPL12MRPL12
Entrez,  Source
mitochondrial ribosomal protein L1216520.1070.4041Yes
63MAOBMAOB
Entrez,  Source
monoamine oxidase B17790.1020.3986Yes
64CYP11B1CYP11B1
Entrez,  Source
cytochrome P450, family 11, subfamily B, polypeptide 117890.1020.4019Yes
65MTIF2MTIF2
Entrez,  Source
mitochondrial translational initiation factor 217970.1010.4055Yes
66NDUFS1NDUFS1
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)18170.1010.4080Yes
67SURF1SURF1
Entrez,  Source
surfeit 118480.1000.4097Yes
68MRPS7MRPS7
Entrez,  Source
mitochondrial ribosomal protein S719300.0960.4074Yes
69SUPV3L1SUPV3L1
Entrez,  Source
suppressor of var1, 3-like 1 (S. cerevisiae)19310.0960.4112Yes
70IDH3AIDH3A
Entrez,  Source
isocitrate dehydrogenase 3 (NAD+) alpha19850.0940.4110Yes
71AKAP1AKAP1
Entrez,  Source
A kinase (PRKA) anchor protein 120000.0940.4137Yes
72COQ7COQ7
Entrez,  Source
coenzyme Q7 homolog, ubiquinone (yeast)20160.0930.4163Yes
73CYP27A1CYP27A1
Entrez,  Source
cytochrome P450, family 27, subfamily A, polypeptide 120330.0930.4187Yes
74GRID2GRID2
Entrez,  Source
glutamate receptor, ionotropic, delta 220990.0910.4174Yes
75NFS1NFS1
Entrez,  Source
NFS1 nitrogen fixation 1 (S. cerevisiae)21000.0910.4211Yes
76MRPS18BMRPS18B
Entrez,  Source
mitochondrial ribosomal protein S18B21180.0900.4234Yes
77GPTGPT
Entrez,  Source
glutamic-pyruvate transaminase (alanine aminotransferase)21460.0900.4249Yes
78COX7BCOX7B
Entrez,  Source
cytochrome c oxidase subunit VIIb21570.0890.4277Yes
79HADHAHADHA
Entrez,  Source
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit21740.0890.4301Yes
80TOMM70ATOMM70A
Entrez,  Source
translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)22680.0860.4264Yes
81ACP6ACP6
Entrez,  Source
acid phosphatase 6, lysophosphatidic22950.0850.4278Yes
82ATP5G2ATP5G2
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9)23180.0850.4295Yes
83MDH2MDH2
Entrez,  Source
malate dehydrogenase 2, NAD (mitochondrial)24090.0820.4259Yes
84ATP5C1ATP5C1
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 124370.0820.4271Yes
85AK2AK2
Entrez,  Source
adenylate kinase 224530.0810.4292Yes
86MRPL34MRPL34
Entrez,  Source
mitochondrial ribosomal protein L3424870.0800.4299Yes
87CPT1BCPT1B
Entrez,  Source
carnitine palmitoyltransferase 1B (muscle)24960.0800.4325Yes
88PRSS15PRSS15
Entrez,  Source
protease, serine, 1525070.0800.4349Yes
89SDHDSDHD
Entrez,  Source
succinate dehydrogenase complex, subunit D, integral membrane protein25290.0790.4365Yes
90ABCB8ABCB8
Entrez,  Source
ATP-binding cassette, sub-family B (MDR/TAP), member 826240.0760.4323No
91IDH3BIDH3B
Entrez,  Source
isocitrate dehydrogenase 3 (NAD+) beta26480.0750.4335No
92NDUFA8NDUFA8
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa27350.0730.4299No
93MRPL2MRPL2
Entrez,  Source
mitochondrial ribosomal protein L227380.0730.4327No
94SDHASDHA
Entrez,  Source
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)27800.0720.4324No
95PDCD8PDCD8
Entrez,  Source
programmed cell death 8 (apoptosis-inducing factor)28030.0710.4336No
96SLC25A1SLC25A1
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 129120.0690.4281No
97DAP3DAP3
Entrez,  Source
death associated protein 329660.0670.4267No
98ENDOGENDOG
Entrez,  Source
endonuclease G29810.0670.4283No
99HSPE1HSPE1
Entrez,  Source
heat shock 10kDa protein 1 (chaperonin 10)30200.0660.4281No
100ACO2ACO2
Entrez,  Source
aconitase 2, mitochondrial31360.0640.4218No
101DLDDLD
Entrez,  Source
dihydrolipoamide dehydrogenase31420.0630.4240No
102MRPL19MRPL19
Entrez,  Source
mitochondrial ribosomal protein L1931660.0630.4247No
103NDUFS2NDUFS2
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)31720.0630.4269No
104DNM1LDNM1L
Entrez,  Source
dynamin 1-like31840.0630.4285No
105UQCRC2UQCRC2
Entrez,  Source
ubiquinol-cytochrome c reductase core protein II31870.0630.4309No
106POLGPOLG
Entrez,  Source
polymerase (DNA directed), gamma32310.0620.4301No
107NDUFA9NDUFA9
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa32530.0610.4309No
108COX5BCOX5B
Entrez,  Source
cytochrome c oxidase subunit Vb32750.0610.4317No
109TIMM17ATIMM17A
Entrez,  Source
translocase of inner mitochondrial membrane 17 homolog A (yeast)32920.0600.4329No
110ABCB6ABCB6
Entrez,  Source
ATP-binding cassette, sub-family B (MDR/TAP), member 633560.0590.4305No
111IDH3GIDH3G
Entrez,  Source
isocitrate dehydrogenase 3 (NAD+) gamma34100.0580.4287No
112PCCBPCCB
Entrez,  Source
propionyl Coenzyme A carboxylase, beta polypeptide34170.0580.4306No
113SLC25A5SLC25A5
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 534180.0580.4329No
114MAOAMAOA
Entrez,  Source
monoamine oxidase A34270.0570.4346No
115MRPL11MRPL11
Entrez,  Source
mitochondrial ribosomal protein L1135290.0550.4291No
116PPIFPPIF
Entrez,  Source
peptidylprolyl isomerase F (cyclophilin F)35430.0550.4303No
117TIMM8BTIMM8B
Entrez,  Source
translocase of inner mitochondrial membrane 8 homolog B (yeast)35590.0550.4313No
118GSRGSR
Entrez,  Source
glutathione reductase35790.0540.4320No
119ATP5EATP5E
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit36340.0530.4300No
120MRPL16MRPL16
Entrez,  Source
mitochondrial ribosomal protein L1636710.0530.4294No
121COX7A2COX7A2
Entrez,  Source
cytochrome c oxidase subunit VIIa polypeptide 2 (liver)36810.0520.4308No
122UROSUROS
Entrez,  Source
uroporphyrinogen III synthase (congenital erythropoietic porphyria)38200.0490.4222No
123ATP5F1ATP5F1
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B138420.0490.4226No
124TRAP1TRAP1
Entrez,  Source
TNF receptor-associated protein 138760.0490.4220No
125MPSTMPST
Entrez,  Source
mercaptopyruvate sulfurtransferase38830.0490.4235No
126UQCRC1UQCRC1
Entrez,  Source
ubiquinol-cytochrome c reductase core protein I39030.0480.4240No
127DBTDBT
Entrez,  Source
dihydrolipoamide branched chain transacylase E239120.0480.4253No
128RAF1RAF1
Entrez,  Source
v-raf-1 murine leukemia viral oncogene homolog 139410.0480.4251No
129TFAMTFAM
Entrez,  Source
transcription factor A, mitochondrial39720.0470.4246No
130SPG7SPG7
Entrez,  Source
spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive)39910.0470.4251No
131UQCRFS1UQCRFS1
Entrez,  Source
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 140730.0450.4207No
132DCIDCI
Entrez,  Source
dodecenoyl-Coenzyme A delta isomerase (3,2 trans-enoyl-Coenzyme A isomerase)41670.0430.4154No
133SLC25A11SLC25A11
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 1141710.0430.4169No
134CSCS
Entrez,  Source
citrate synthase41750.0430.4184No
135ATP5BATP5B
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide41930.0430.4188No
136ATP5JATP5J
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F641940.0430.4205No
137STARSTAR
Entrez,  Source
steroidogenic acute regulator42090.0430.4212No
138BCL2L11BCL2L11
Entrez,  Source
BCL2-like 11 (apoptosis facilitator)42160.0430.4224No
139CYP27B1CYP27B1
Entrez,  Source
cytochrome P450, family 27, subfamily B, polypeptide 142180.0430.4240No
140ATP5G3ATP5G3
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)42220.0430.4255No
141ATP5IATP5I
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit E42690.0420.4237No
142PRDX3PRDX3
Entrez,  Source
peroxiredoxin 342710.0420.4252No
143ATP7BATP7B
Entrez,  Source
ATPase, Cu++ transporting, beta polypeptide42910.0410.4255No
144ACADMACADM
Entrez,  Source
acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain42990.0410.4266No
145DLSTDLST
Entrez,  Source
dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)43350.0400.4255No
146COX6A1COX6A1
Entrez,  Source
cytochrome c oxidase subunit VIa polypeptide 143670.0400.4247No
147BLVRABLVRA
Entrez,  Source
biliverdin reductase A43800.0400.4254No
148SSBP1SSBP1
Entrez,  Source
single-stranded DNA binding protein 144110.0390.4247No
149COX5ACOX5A
Entrez,  Source
cytochrome c oxidase subunit Va44420.0390.4240No
150ATP5HATP5H
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d44810.0380.4226No
151NDUFC2NDUFC2
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa45790.0360.4166No
152HADHBHADHB
Entrez,  Source
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit46750.0350.4108No
153NDUFS4NDUFS4
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)47530.0330.4062No
154IVDIVD
Entrez,  Source
isovaleryl Coenzyme A dehydrogenase47830.0330.4053No
155NDUFS6NDUFS6
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)48990.0310.3978No
156HSD3B1HSD3B1
Entrez,  Source
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 149970.0290.3915No
157MRPL44MRPL44
Entrez,  Source
mitochondrial ribosomal protein L4450270.0290.3904No
158COX6CCOX6C
Entrez,  Source
cytochrome c oxidase subunit VIc50360.0290.3910No
159TXNRD2TXNRD2
Entrez,  Source
thioredoxin reductase 250550.0280.3907No
160GLUD1GLUD1
Entrez,  Source
glutamate dehydrogenase 150870.0280.3895No
161TIMM13TIMM13
Entrez,  Source
translocase of inner mitochondrial membrane 13 homolog (yeast)51460.0270.3861No
162GALR3GALR3
Entrez,  Source
galanin receptor 351860.0260.3842No
163CLN3CLN3
Entrez,  Source
ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)52080.0260.3836No
164TOMM40TOMM40
Entrez,  Source
translocase of outer mitochondrial membrane 40 homolog (yeast)52280.0260.3832No
165UQCRBUQCRB
Entrez,  Source
ubiquinol-cytochrome c reductase binding protein52310.0260.3841No
166COX4I1COX4I1
Entrez,  Source
cytochrome c oxidase subunit IV isoform 152450.0250.3841No
167NR3C1NR3C1
Entrez,  Source
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)52520.0250.3847No
168CYBBCYBB
Entrez,  Source
cytochrome b-245, beta polypeptide (chronic granulomatous disease)53120.0240.3811No
169ATP5DATP5D
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit53230.0240.3814No
170ETFAETFA
Entrez,  Source
electron-transfer-flavoprotein, alpha polypeptide (glutaric aciduria II)53360.0240.3814No
171CA5BCA5B
Entrez,  Source
carbonic anhydrase VB, mitochondrial53380.0240.3823No
172GPX4GPX4
Entrez,  Source
glutathione peroxidase 4 (phospholipid hydroperoxidase)53730.0240.3806No
173ATP5SATP5S
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit s (factor B)54140.0230.3785No
174MRPL24MRPL24
Entrez,  Source
mitochondrial ribosomal protein L2454440.0230.3772No
175MRPL17MRPL17
Entrez,  Source
mitochondrial ribosomal protein L1754580.0220.3771No
176ODC1ODC1
Entrez,  Source
ornithine decarboxylase 154870.0220.3758No
177AK3AK3
Entrez,  Source
adenylate kinase 355400.0210.3727No
178OPA1OPA1
Entrez,  Source
optic atrophy 1 (autosomal dominant)56200.0200.3675No
179IMMTIMMT
Entrez,  Source
inner membrane protein, mitochondrial (mitofilin)56520.0200.3659No
180NDUFB4NDUFB4
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa56560.0190.3664No
181SLC25A21SLC25A21
Entrez,  Source
solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 2156790.0190.3655No
182SUCLG1SUCLG1
Entrez,  Source
succinate-CoA ligase, GDP-forming, alpha subunit57380.0180.3618No
183SDHCSDHC
Entrez,  Source
succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa57890.0180.3587No
184PDHA1PDHA1
Entrez,  Source
pyruvate dehydrogenase (lipoamide) alpha 157970.0170.3588No
185ACADLACADL
Entrez,  Source
acyl-Coenzyme A dehydrogenase, long chain58120.0170.3585No
186ACADSACADS
Entrez,  Source
acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain58860.0160.3535No
187GOT2GOT2
Entrez,  Source
glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)59160.0150.3519No
188DHODHDHODH
Entrez,  Source
dihydroorotate dehydrogenase59330.0150.3513No
189MRPL9MRPL9
Entrez,  Source
mitochondrial ribosomal protein L959570.0150.3501No
190VDAC2VDAC2
Entrez,  Source
voltage-dependent anion channel 259870.0140.3485No
191TOMM22TOMM22
Entrez,  Source
translocase of outer mitochondrial membrane 22 homolog (yeast)60980.0130.3406No
192OGG1OGG1
Entrez,  Source
8-oxoguanine DNA glycosylase61180.0130.3397No
193BIDBID
Entrez,  Source
BH3 interacting domain death agonist61250.0120.3397No
194ALDH2ALDH2
Entrez,  Source
aldehyde dehydrogenase 2 family (mitochondrial)61750.0120.3364No
195GPD2GPD2
Entrez,  Source
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)62370.0110.3322No
196HSPD1HSPD1
Entrez,  Source
heat shock 60kDa protein 1 (chaperonin)62420.0110.3323No
197RPS3ARPS3A
Entrez,  Source
ribosomal protein S3A63200.0090.3268No
198MRPL13MRPL13
Entrez,  Source
mitochondrial ribosomal protein L1363630.0080.3239No
199FDXRFDXR
Entrez,  Source
ferredoxin reductase63910.0080.3222No
200HCLS1HCLS1
Entrez,  Source
hematopoietic cell-specific Lyn substrate 164050.0080.3215No
201UCP1UCP1
Entrez,  Source
uncoupling protein 1 (mitochondrial, proton carrier)64210.0070.3206No
202ARG2ARG2
Entrez,  Source
arginase, type II65800.0060.3088No
203CYCSCYCS
Entrez,  Source
cytochrome c, somatic67070.0040.2993No
204RPL3RPL3
Entrez,  Source
ribosomal protein L369560.0000.2804No
205TOMM20TOMM20
Entrez,  Source
translocase of outer mitochondrial membrane 20 homolog (yeast)7046-0.0010.2736No
206PPIDPPID
Entrez,  Source
peptidylprolyl isomerase D (cyclophilin D)7131-0.0020.2673No
207MTERFMTERF
Entrez,  Source
mitochondrial transcription termination factor7209-0.0030.2615No
208NDUFA5NDUFA5
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa7283-0.0040.2561No
209UQCRHUQCRH
Entrez,  Source
ubiquinol-cytochrome c reductase hinge protein7358-0.0050.2507No
210MUTYHMUTYH
Entrez,  Source
mutY homolog (E. coli)7604-0.0090.2323No
211PMPCBPMPCB
Entrez,  Source
peptidase (mitochondrial processing) beta7633-0.0100.2306No
212BNIP3BNIP3
Entrez,  Source
BCL2/adenovirus E1B 19kDa interacting protein 37875-0.0130.2127No
213FRAP1FRAP1
Entrez,  Source
FK506 binding protein 12-rapamycin associated protein 18101-0.0160.1961No
214TIMM44TIMM44
Entrez,  Source
translocase of inner mitochondrial membrane 44 homolog (yeast)8155-0.0170.1928No
215UCP3UCP3
Entrez,  Source
uncoupling protein 3 (mitochondrial, proton carrier)8164-0.0170.1929No
216TIMM22TIMM22
Entrez,  Source
translocase of inner mitochondrial membrane 22 homolog (yeast)8179-0.0180.1925No
217ATPIF1ATPIF1
Entrez,  Source
ATPase inhibitory factor 18423-0.0220.1748No
218SDSSDS
Entrez,  Source
serine dehydratase8683-0.0260.1560No
219DIABLODIABLO
Entrez,  Source
diablo homolog (Drosophila)8809-0.0280.1476No
220SLC1A3SLC1A3
Entrez,  Source
solute carrier family 1 (glial high affinity glutamate transporter), member 38857-0.0290.1452No
221BCL2BCL2
Entrez,  Source
B-cell CLL/lymphoma 28887-0.0300.1442No
222MFN2MFN2
Entrez,  Source
mitofusin 29004-0.0320.1366No
223SLC1A1SLC1A1
Entrez,  Source
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 19452-0.0410.1041No
224LYPLA2LYPLA2
Entrez,  Source
lysophospholipase II9600-0.0430.0946No
225VDAC3VDAC3
Entrez,  Source
voltage-dependent anion channel 39603-0.0430.0962No
226MRPS18AMRPS18A
Entrez,  Source
mitochondrial ribosomal protein S18A9675-0.0450.0926No
227BAXBAX
Entrez,  Source
BCL2-associated X protein9773-0.0470.0870No
228BCAT2BCAT2
Entrez,  Source
branched chain aminotransferase 2, mitochondrial9815-0.0480.0858No
229MRPL49MRPL49
Entrez,  Source
mitochondrial ribosomal protein L499821-0.0480.0874No
230CYP11A1CYP11A1
Entrez,  Source
cytochrome P450, family 11, subfamily A, polypeptide 110102-0.0540.0682No
231COX15COX15
Entrez,  Source
COX15 homolog, cytochrome c oxidase assembly protein (yeast)10424-0.0620.0461No
232BCL2L1BCL2L1
Entrez,  Source
BCL2-like 110828-0.0730.0182No
233DUTDUT
Entrez,  Source
dUTP pyrophosphatase10990-0.0780.0091No
234DLATDLAT
Entrez,  Source
dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)10995-0.0780.0119No
235SLC25A3SLC25A3
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 311129-0.0830.0051No
236BNIP3LBNIP3L
Entrez,  Source
BCL2/adenovirus E1B 19kDa interacting protein 3-like11360-0.093-0.0088No
237FDX1FDX1
Entrez,  Source
ferredoxin 111489-0.099-0.0146No
238GATMGATM
Entrez,  Source
glycine amidinotransferase (L-arginine:glycine amidinotransferase)11580-0.103-0.0173No
239PPM2CPPM2C
Entrez,  Source
protein phosphatase 2C, magnesium-dependent, catalytic subunit11644-0.106-0.0179No
240FIBPFIBP
Entrez,  Source
fibroblast growth factor (acidic) intracellular binding protein11877-0.118-0.0309No
241MTCH1MTCH1
Entrez,  Source
mitochondrial carrier homolog 1 (C. elegans)12038-0.127-0.0380No
242HK1HK1
Entrez,  Source
hexokinase 112060-0.129-0.0345No
243BAK1BAK1
Entrez,  Source
BCL2-antagonist/killer 112070-0.129-0.0300No
244DNASE2DNASE2
Entrez,  Source
deoxyribonuclease II, lysosomal12199-0.139-0.0342No
245BADBAD
Entrez,  Source
BCL2-antagonist of cell death12355-0.153-0.0399No
246CASP8CASP8
Entrez,  Source
caspase 8, apoptosis-related cysteine peptidase12395-0.157-0.0366No
247UCP2UCP2
Entrez,  Source
uncoupling protein 2 (mitochondrial, proton carrier)12505-0.172-0.0381No
248GLSGLS
Entrez,  Source
glutaminase12588-0.183-0.0370No
249SLC25A4SLC25A4
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 412710-0.207-0.0380No
250CYBACYBA
Entrez,  Source
cytochrome b-245, alpha polypeptide12921-0.260-0.0437No
251CRATCRAT
Entrez,  Source
carnitine acetyltransferase13012-0.297-0.0387No
252COX6A2COX6A2
Entrez,  Source
cytochrome c oxidase subunit VIa polypeptide 213057-0.324-0.0290No
253APAF1APAF1
Entrez,  Source
apoptotic peptidase activating factor13156-0.411-0.0201No
254POPDC2POPDC2
Entrez,  Source
popeye domain containing 213157-0.411-0.0037No
255NGFRAP1NGFRAP1
Entrez,  Source
nerve growth factor receptor (TNFRSF16) associated protein 113183-0.4430.0121No
Table: GSEA details [plain text format]



Fig 2: HUMAN_MITODB_6_2002   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: HUMAN_MITODB_6_2002: Random ES distribution   
Gene set null distribution of ES for HUMAN_MITODB_6_2002