Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | HYPOPHYSECTOMY_RAT_DN |
| Enrichment Score (ES) | 0.57889014 |
| Normalized Enrichment Score (NES) | 1.9214475 |
| Nominal p-value | 0.0023255814 |
| FDR q-value | 0.006191559 |
| FWER p-Value | 0.362 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FBP1 | FBP1 Entrez, Source | fructose-1,6-bisphosphatase 1 | 43 | 0.515 | 0.1115 | Yes |
| 2 | ACAA2 | ACAA2 Entrez, Source | acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase) | 135 | 0.374 | 0.1881 | Yes |
| 3 | AQP8 | AQP8 Entrez, Source | aquaporin 8 | 195 | 0.312 | 0.2531 | Yes |
| 4 | PDK4 | PDK4 Entrez, Source | pyruvate dehydrogenase kinase, isozyme 4 | 412 | 0.227 | 0.2875 | Yes |
| 5 | ALAS1 | ALAS1 Entrez, Source | aminolevulinate, delta-, synthase 1 | 419 | 0.224 | 0.3371 | Yes |
| 6 | FDPS | FDPS Entrez, Source | farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase) | 462 | 0.212 | 0.3812 | Yes |
| 7 | ACSL1 | ACSL1 Entrez, Source | acyl-CoA synthetase long-chain family member 1 | 609 | 0.185 | 0.4114 | Yes |
| 8 | CYB5B | CYB5B Entrez, Source | cytochrome b5 type B (outer mitochondrial membrane) | 632 | 0.182 | 0.4503 | Yes |
| 9 | OAT | OAT Entrez, Source | ornithine aminotransferase (gyrate atrophy) | 893 | 0.154 | 0.4650 | Yes |
| 10 | MGP | MGP Entrez, Source | matrix Gla protein | 1003 | 0.144 | 0.4889 | Yes |
| 11 | ALDOB | ALDOB Entrez, Source | aldolase B, fructose-bisphosphate | 1007 | 0.144 | 0.5207 | Yes |
| 12 | SCD | SCD Entrez, Source | stearoyl-CoA desaturase (delta-9-desaturase) | 1291 | 0.125 | 0.5272 | Yes |
| 13 | IDH1 | IDH1 Entrez, Source | isocitrate dehydrogenase 1 (NADP+), soluble | 1494 | 0.114 | 0.5373 | Yes |
| 14 | DECR1 | DECR1 Entrez, Source | 2,4-dienoyl CoA reductase 1, mitochondrial | 1588 | 0.109 | 0.5546 | Yes |
| 15 | HADH | HADH Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase | 1622 | 0.108 | 0.5762 | Yes |
| 16 | PEX19 | PEX19 Entrez, Source | peroxisomal biogenesis factor 19 | 1878 | 0.098 | 0.5789 | Yes |
| 17 | TKT | TKT Entrez, Source | transketolase (Wernicke-Korsakoff syndrome) | 2441 | 0.081 | 0.5547 | No |
| 18 | CALR | CALR Entrez, Source | calreticulin | 2497 | 0.080 | 0.5684 | No |
| 19 | NPPA | NPPA Entrez, Source | natriuretic peptide precursor A | 3206 | 0.062 | 0.5290 | No |
| 20 | PIM3 | PIM3 Entrez, Source | pim-3 oncogene | 3391 | 0.058 | 0.5281 | No |
| 21 | RAB3B | RAB3B Entrez, Source | RAB3B, member RAS oncogene family | 3815 | 0.050 | 0.5073 | No |
| 22 | TFF3 | TFF3 Entrez, Source | trefoil factor 3 (intestinal) | 4555 | 0.037 | 0.4600 | No |
| 23 | GLUD1 | GLUD1 Entrez, Source | glutamate dehydrogenase 1 | 5087 | 0.028 | 0.4262 | No |
| 24 | SLC9A1 | SLC9A1 Entrez, Source | solute carrier family 9 (sodium/hydrogen exchanger), member 1 (antiporter, Na+/H+, amiloride sensitive) | 5235 | 0.026 | 0.4209 | No |
| 25 | DAD1 | DAD1 Entrez, Source | defender against cell death 1 | 5314 | 0.024 | 0.4205 | No |
| 26 | ODC1 | ODC1 Entrez, Source | ornithine decarboxylase 1 | 5487 | 0.022 | 0.4124 | No |
| 27 | SPARC | SPARC Entrez, Source | secreted protein, acidic, cysteine-rich (osteonectin) | 5548 | 0.021 | 0.4126 | No |
| 28 | ECH1 | ECH1 Entrez, Source | enoyl Coenzyme A hydratase 1, peroxisomal | 5859 | 0.016 | 0.3929 | No |
| 29 | PADI4 | PADI4 Entrez, Source | peptidyl arginine deiminase, type IV | 6014 | 0.014 | 0.3844 | No |
| 30 | FTH1 | FTH1 Entrez, Source | ferritin, heavy polypeptide 1 | 6187 | 0.012 | 0.3741 | No |
| 31 | AHSG | AHSG Entrez, Source | alpha-2-HS-glycoprotein | 6354 | 0.009 | 0.3635 | No |
| 32 | FBLN5 | FBLN5 Entrez, Source | fibulin 5 | 6439 | 0.007 | 0.3588 | No |
| 33 | MEP1B | MEP1B Entrez, Source | meprin A, beta | 7105 | -0.002 | 0.3092 | No |
| 34 | AKR1A1 | AKR1A1 Entrez, Source | aldo-keto reductase family 1, member A1 (aldehyde reductase) | 7127 | -0.002 | 0.3080 | No |
| 35 | LDHA | LDHA Entrez, Source | lactate dehydrogenase A | 7676 | -0.010 | 0.2691 | No |
| 36 | LIMS2 | LIMS2 Entrez, Source | LIM and senescent cell antigen-like domains 2 | 7865 | -0.013 | 0.2579 | No |
| 37 | DDC | DDC Entrez, Source | dopa decarboxylase (aromatic L-amino acid decarboxylase) | 8401 | -0.021 | 0.2224 | No |
| 38 | DCN | DCN Entrez, Source | decorin | 8600 | -0.025 | 0.2130 | No |
| 39 | PDIA3 | PDIA3 Entrez, Source | protein disulfide isomerase family A, member 3 | 9691 | -0.045 | 0.1412 | No |
| 40 | ATP2A2 | ATP2A2 Entrez, Source | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 9784 | -0.048 | 0.1448 | No |
| 41 | ARF4 | ARF4 Entrez, Source | ADP-ribosylation factor 4 | 9911 | -0.050 | 0.1466 | No |
| 42 | B2M | B2M Entrez, Source | beta-2-microglobulin | 9941 | -0.051 | 0.1557 | No |
| 43 | FN1 | FN1 Entrez, Source | fibronectin 1 | 10062 | -0.053 | 0.1586 | No |
| 44 | PSMB8 | PSMB8 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) | 10371 | -0.061 | 0.1489 | No |
| 45 | PPGB | PPGB Entrez, Source | protective protein for beta-galactosidase (galactosialidosis) | 12387 | -0.157 | 0.0323 | No |
| 46 | COL3A1 | COL3A1 Entrez, Source | collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) | 12541 | -0.177 | 0.0602 | No |
