Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | HYPOXIA_REG_UP |
| Enrichment Score (ES) | -0.60798913 |
| Normalized Enrichment Score (NES) | -1.7144575 |
| Nominal p-value | 0.0069444445 |
| FDR q-value | 0.057915594 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PPP1R3C | PPP1R3C Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 3C | 71 | 0.452 | 0.0688 | No |
| 2 | DDIT4 | DDIT4 Entrez, Source | DNA-damage-inducible transcript 4 | 472 | 0.210 | 0.0731 | No |
| 3 | BHLHB2 | BHLHB2 Entrez, Source | basic helix-loop-helix domain containing, class B, 2 | 613 | 0.184 | 0.0928 | No |
| 4 | RASGRP1 | RASGRP1 Entrez, Source | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | 767 | 0.165 | 0.1085 | No |
| 5 | VEGF | VEGF Entrez, Source | vascular endothelial growth factor | 901 | 0.153 | 0.1235 | No |
| 6 | TGFA | TGFA Entrez, Source | transforming growth factor, alpha | 986 | 0.146 | 0.1411 | No |
| 7 | PTDSR | PTDSR Entrez, Source | phosphatidylserine receptor | 1122 | 0.135 | 0.1532 | No |
| 8 | JUNB | JUNB Entrez, Source | jun B proto-oncogene | 1487 | 0.114 | 0.1445 | No |
| 9 | PFKFB4 | PFKFB4 Entrez, Source | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 1785 | 0.102 | 0.1389 | No |
| 10 | STC2 | STC2 Entrez, Source | stanniocalcin 2 | 2436 | 0.082 | 0.1034 | No |
| 11 | EFNA1 | EFNA1 Entrez, Source | ephrin-A1 | 3378 | 0.058 | 0.0423 | No |
| 12 | NFIL3 | NFIL3 Entrez, Source | nuclear factor, interleukin 3 regulated | 4177 | 0.043 | -0.0105 | No |
| 13 | SLC7A5 | SLC7A5 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 | 4470 | 0.038 | -0.0262 | No |
| 14 | MUC1 | MUC1 Entrez, Source | mucin 1, cell surface associated | 5222 | 0.026 | -0.0783 | No |
| 15 | ADFP | ADFP Entrez, Source | adipose differentiation-related protein | 5901 | 0.016 | -0.1267 | No |
| 16 | HNRPA1 | HNRPA1 Entrez, Source | heterogeneous nuclear ribonucleoprotein A1 | 6063 | 0.013 | -0.1366 | No |
| 17 | DUSP1 | DUSP1 Entrez, Source | dual specificity phosphatase 1 | 6673 | 0.004 | -0.1817 | No |
| 18 | PGK1 | PGK1 Entrez, Source | phosphoglycerate kinase 1 | 7152 | -0.002 | -0.2172 | No |
| 19 | FUS | FUS Entrez, Source | fusion (involved in t(12;16) in malignant liposarcoma) | 7497 | -0.007 | -0.2418 | No |
| 20 | BNIP3 | BNIP3 Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 3 | 7875 | -0.013 | -0.2680 | No |
| 21 | ALDOA | ALDOA Entrez, Source | aldolase A, fructose-bisphosphate | 9779 | -0.047 | -0.4031 | No |
| 22 | PHC2 | PHC2 Entrez, Source | polyhomeotic homolog 2 (Drosophila) | 11283 | -0.090 | -0.5014 | No |
| 23 | CDKN1B | CDKN1B Entrez, Source | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 11886 | -0.118 | -0.5272 | No |
| 24 | SLC2A1 | SLC2A1 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 1 | 12962 | -0.277 | -0.5626 | Yes |
| 25 | SLC16A3 | SLC16A3 Entrez, Source | solute carrier family 16, member 3 (monocarboxylic acid transporter 4) | 12983 | -0.284 | -0.5176 | Yes |
| 26 | ADORA2B | ADORA2B Entrez, Source | adenosine A2b receptor | 13103 | -0.358 | -0.4677 | Yes |
| 27 | SERPINE1 | SERPINE1 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 13125 | -0.378 | -0.4074 | Yes |
| 28 | PFKP | PFKP Entrez, Source | phosphofructokinase, platelet | 13129 | -0.381 | -0.3451 | Yes |
| 29 | ADM | ADM Entrez, Source | adrenomedullin | 13287 | -0.697 | -0.2426 | Yes |
| 30 | GPRC5A | GPRC5A Entrez, Source | G protein-coupled receptor, family C, group 5, member A | 13289 | -0.705 | -0.1272 | Yes |
| 31 | F3 | F3 Entrez, Source | coagulation factor III (thromboplastin, tissue factor) | 13308 | -0.800 | 0.0026 | Yes |
