Details for gene set ICHIBA

Table: GSEA Results Summary

Dataset	double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos
Phenotype	class.cls#double_gel_72h_versus_single_gel_72h_repos
Upregulated in class	double_gel_72h
GeneSet	ICHIBA_GVHD
Enrichment Score (ES)	0.36842096
Normalized Enrichment Score (NES)	1.5007988
Nominal p-value	0.002994012
FDR q-value	0.12094261
FWER p-Value	1.0

Table: GSEA details [plain text format]
	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	FABP1	FABP1 Entrez, Source	fatty acid binding protein 1, liver	2	1.112	0.0407	Yes
2	PKLR	PKLR Entrez, Source	pyruvate kinase, liver and RBC	31	0.561	0.0592	Yes
3	KEG1			47	0.503	0.0765	Yes
4	VCAM1	VCAM1 Entrez, Source	vascular cell adhesion molecule 1	49	0.501	0.0948	Yes
5	CD5L	CD5L Entrez, Source	CD5 molecule-like	51	0.497	0.1130	Yes
6	PPP1R3C	PPP1R3C Entrez, Source	protein phosphatase 1, regulatory (inhibitor) subunit 3C	71	0.452	0.1282	Yes
7	ELOVL6	ELOVL6 Entrez, Source	ELOVL family member 6, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)	83	0.433	0.1433	Yes
8	HMGCS2	HMGCS2 Entrez, Source	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial)	117	0.396	0.1553	Yes
9	G6PC	G6PC Entrez, Source	glucose-6-phosphatase, catalytic subunit	129	0.383	0.1686	Yes
10	XDH	XDH Entrez, Source	xanthine dehydrogenase	134	0.375	0.1820	Yes
11	SLC26A1	SLC26A1 Entrez, Source	solute carrier family 26 (sulfate transporter), member 1	166	0.342	0.1922	Yes
12	IL1RN	IL1RN Entrez, Source	interleukin 1 receptor antagonist	175	0.333	0.2038	Yes
13	GHR	GHR Entrez, Source	growth hormone receptor	250	0.287	0.2088	Yes
14	C1QC	C1QC Entrez, Source	complement component 1, q subcomponent, C chain	253	0.286	0.2192	Yes
15	PRLR	PRLR Entrez, Source	prolactin receptor	257	0.285	0.2294	Yes
16	CSF1R	CSF1R Entrez, Source	colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog	313	0.263	0.2349	Yes
17	LIFR	LIFR Entrez, Source	leukemia inhibitory factor receptor alpha	339	0.253	0.2422	Yes
18	SNX10	SNX10 Entrez, Source	sorting nexin 10	353	0.248	0.2504	Yes
19	CD68	CD68 Entrez, Source	CD68 molecule	365	0.244	0.2585	Yes
20	SLC25A10	SLC25A10 Entrez, Source	solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10	378	0.240	0.2664	Yes
21	C1QB	C1QB Entrez, Source	complement component 1, q subcomponent, B chain	383	0.238	0.2748	Yes
22	CD14	CD14 Entrez, Source	CD14 molecule	400	0.231	0.2821	Yes
23	FKBP5	FKBP5 Entrez, Source	FK506 binding protein 5	406	0.229	0.2901	Yes
24	CCL6			427	0.223	0.2968	Yes
25	NAT8	NAT8 Entrez, Source	N-acetyltransferase 8 (camello like)	431	0.221	0.3046	Yes
26	CTSS	CTSS Entrez, Source	cathepsin S	456	0.214	0.3107	Yes
27	LBP	LBP Entrez, Source	lipopolysaccharide binding protein	476	0.209	0.3169	Yes
28	SC5DL	SC5DL Entrez, Source	sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, fungal)-like	512	0.201	0.3216	Yes
29	C1QA	C1QA Entrez, Source	complement component 1, q subcomponent, A chain	518	0.198	0.3285	Yes
30	IGFALS	IGFALS Entrez, Source	insulin-like growth factor binding protein, acid labile subunit	533	0.196	0.3346	Yes
31	CYP26A1	CYP26A1 Entrez, Source	cytochrome P450, family 26, subfamily A, polypeptide 1	562	0.191	0.3395	Yes
32	CYP8B1	CYP8B1 Entrez, Source	cytochrome P450, family 8, subfamily B, polypeptide 1	594	0.187	0.3440	Yes
33	ACSL1	ACSL1 Entrez, Source	acyl-CoA synthetase long-chain family member 1	609	0.185	0.3497	Yes
34	LPHN1	LPHN1 Entrez, Source	latrophilin 1	621	0.184	0.3556	Yes
35	FKBP11	FKBP11 Entrez, Source	FK506 binding protein 11, 19 kDa	737	0.169	0.3531	Yes
36	TYROBP	TYROBP Entrez, Source	TYRO protein tyrosine kinase binding protein	747	0.168	0.3586	Yes
37	ELAC2	ELAC2 Entrez, Source	elaC homolog 2 (E. coli)	873	0.155	0.3548	Yes
38	EIF1	EIF1 Entrez, Source	eukaryotic translation initiation factor 1	876	0.155	0.3603	Yes
39	OAT	OAT Entrez, Source	ornithine aminotransferase (gyrate atrophy)	893	0.154	0.3648	Yes
40	CRYL1	CRYL1 Entrez, Source	crystallin, lambda 1	919	0.151	0.3684	Yes
41	CES3	CES3 Entrez, Source	carboxylesterase 3 (brain)	1183	0.131	0.3533	No
42	PAX3	PAX3 Entrez, Source	paired box gene 3 (Waardenburg syndrome 1)	1312	0.123	0.3481	No
43	RND2	RND2 Entrez, Source	Rho family GTPase 2	1395	0.119	0.3462	No
44	CCR1	CCR1 Entrez, Source	chemokine (C-C motif) receptor 1	1404	0.119	0.3499	No
45	IRF8	IRF8 Entrez, Source	interferon regulatory factor 8	1460	0.115	0.3500	No
46	FAS	FAS Entrez, Source	Fas (TNF receptor superfamily, member 6)	1520	0.112	0.3497	No
47	CD74	CD74 Entrez, Source	CD74 molecule, major histocompatibility complex, class II invariant chain	1524	0.112	0.3535	No
48	ICAM1	ICAM1 Entrez, Source	intercellular adhesion molecule 1 (CD54), human rhinovirus receptor	1644	0.107	0.3484	No
49	KLF10	KLF10 Entrez, Source	Kruppel-like factor 10	1693	0.105	0.3486	No
50	TSPAN4	TSPAN4 Entrez, Source	tetraspanin 4	1713	0.105	0.3510	No
51	CTSE	CTSE Entrez, Source	cathepsin E	1718	0.104	0.3546	No
52	S100A9	S100A9 Entrez, Source	S100 calcium binding protein A9	1830	0.100	0.3498	No
53	PBEF1	PBEF1 Entrez, Source	pre-B-cell colony enhancing factor 1	1897	0.097	0.3484	No
54	HCK	HCK Entrez, Source	hemopoietic cell kinase	1900	0.097	0.3518	No
55	CXCL10	CXCL10 Entrez, Source	chemokine (C-X-C motif) ligand 10	2004	0.094	0.3474	No
56	NFKBIA	NFKBIA Entrez, Source	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	2241	0.087	0.3327	No
57	HP	HP Entrez, Source	haptoglobin	2321	0.084	0.3298	No
58	CXCL1	CXCL1 Entrez, Source	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	2338	0.084	0.3317	No
59	UBD	UBD Entrez, Source	ubiquitin D	2423	0.082	0.3283	No
60	CYP2B13			2424	0.082	0.3313	No
61	CD53	CD53 Entrez, Source	CD53 molecule	2467	0.081	0.3311	No
62	PDZK1	PDZK1 Entrez, Source	PDZ domain containing 1	2470	0.081	0.3339	No
63	RBM13	RBM13 Entrez, Source	RNA binding motif protein 13	2581	0.077	0.3284	No
64	HSD17B2	HSD17B2 Entrez, Source	hydroxysteroid (17-beta) dehydrogenase 2	2586	0.077	0.3309	No
65	FGL2	FGL2 Entrez, Source	fibrinogen-like 2	2640	0.075	0.3296	No
66	VNN1	VNN1 Entrez, Source	vanin 1	2659	0.075	0.3310	No
67	PSMB10	PSMB10 Entrez, Source	proteasome (prosome, macropain) subunit, beta type, 10	2919	0.068	0.3138	No
68	IFIT3	IFIT3 Entrez, Source	interferon-induced protein with tetratricopeptide repeats 3	2944	0.068	0.3145	No
69	ELA1	ELA1 Entrez, Source	elastase 1, pancreatic	2955	0.067	0.3162	No
70	SCD5	SCD5 Entrez, Source	stearoyl-CoA desaturase 5	3057	0.065	0.3109	No
71	MMP12	MMP12 Entrez, Source	matrix metallopeptidase 12 (macrophage elastase)	3186	0.063	0.3035	No
72	EMR1	EMR1 Entrez, Source	egf-like module containing, mucin-like, hormone receptor-like 1	3196	0.062	0.3051	No
73	GIMAP4	GIMAP4 Entrez, Source	GTPase, IMAP family member 4	3337	0.059	0.2967	No
74	STAT1	STAT1 Entrez, Source	signal transducer and activator of transcription 1, 91kDa	3416	0.058	0.2928	No
75	RPAP1	RPAP1 Entrez, Source	RNA polymerase II associated protein 1	3518	0.056	0.2872	No
76	IL6ST	IL6ST Entrez, Source	interleukin 6 signal transducer (gp130, oncostatin M receptor)	3732	0.051	0.2729	No
77	CTSC	CTSC Entrez, Source	cathepsin C	3796	0.050	0.2700	No
78	CASP1	CASP1 Entrez, Source	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	4076	0.045	0.2504	No
79	APBB1IP	APBB1IP Entrez, Source	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein	4111	0.044	0.2495	No
80	IFIT1	IFIT1 Entrez, Source	interferon-induced protein with tetratricopeptide repeats 1	4461	0.038	0.2244	No
81	MARVELD1	MARVELD1 Entrez, Source	MARVEL domain containing 1	4468	0.038	0.2253	No
82	TFF3	TFF3 Entrez, Source	trefoil factor 3 (intestinal)	4555	0.037	0.2201	No
83	BTG2	BTG2 Entrez, Source	BTG family, member 2	4648	0.035	0.2144	No
84	LAPTM5	LAPTM5 Entrez, Source	lysosomal associated multispanning membrane protein 5	4666	0.035	0.2144	No
85	ORM1	ORM1 Entrez, Source	orosomucoid 1	4816	0.032	0.2043	No
86	PTGS1	PTGS1 Entrez, Source	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	4887	0.031	0.2001	No
87	SULT4A1	SULT4A1 Entrez, Source	sulfotransferase family 4A, member 1	4903	0.031	0.2001	No
88	MT1A	MT1A Entrez, Source	metallothionein 1A (functional)	5078	0.028	0.1879	No
89	ADRB3	ADRB3 Entrez, Source	adrenergic, beta-3-, receptor	5121	0.027	0.1857	No
90	CYBB	CYBB Entrez, Source	cytochrome b-245, beta polypeptide (chronic granulomatous disease)	5312	0.024	0.1722	No
91	MKLN1	MKLN1 Entrez, Source	muskelin 1, intracellular mediator containing kelch motifs	5396	0.023	0.1667	No
92	NR1D1	NR1D1 Entrez, Source	nuclear receptor subfamily 1, group D, member 1	5562	0.021	0.1550	No
93	ALAS2	ALAS2 Entrez, Source	aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia)	5606	0.020	0.1524	No
94	PTPRC	PTPRC Entrez, Source	protein tyrosine phosphatase, receptor type, C	5608	0.020	0.1531	No
95	PRM3	PRM3 Entrez, Source	protamine 3	5680	0.019	0.1484	No
96	SIRPA	SIRPA Entrez, Source	signal-regulatory protein alpha	5733	0.018	0.1451	No
97	SLC1A2	SLC1A2 Entrez, Source	solute carrier family 1 (glial high affinity glutamate transporter), member 2	6115	0.013	0.1167	No
98	LRG1	LRG1 Entrez, Source	leucine-rich alpha-2-glycoprotein 1	6198	0.011	0.1108	No
99	FCGR1			6231	0.011	0.1088	No
100	SERPINA10	SERPINA10 Entrez, Source	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10	6262	0.010	0.1069	No
101	HES6	HES6 Entrez, Source	hairy and enhancer of split 6 (Drosophila)	6341	0.009	0.1013	No
102	CRYAA	CRYAA Entrez, Source	crystallin, alpha A	6379	0.008	0.0988	No
103	SOCS1	SOCS1 Entrez, Source	suppressor of cytokine signaling 1	6382	0.008	0.0989	No
104	IL18BP	IL18BP Entrez, Source	interleukin 18 binding protein	6423	0.007	0.0962	No
105	LCP2	LCP2 Entrez, Source	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	6665	0.004	0.0780	No
106	CCL4	CCL4 Entrez, Source	chemokine (C-C motif) ligand 4	6696	0.004	0.0759	No
107	IRF1	IRF1 Entrez, Source	interferon regulatory factor 1	6764	0.003	0.0709	No
108	CXCL9	CXCL9 Entrez, Source	chemokine (C-X-C motif) ligand 9	6813	0.002	0.0674	No
109	PSME1	PSME1 Entrez, Source	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)	6880	0.002	0.0624	No
110	SNX27	SNX27 Entrez, Source	sorting nexin family member 27	6946	0.000	0.0575	No
111	CD52	CD52 Entrez, Source	CD52 molecule	7261	-0.004	0.0338	No
112	CCL5	CCL5 Entrez, Source	chemokine (C-C motif) ligand 5	7275	-0.004	0.0329	No
113	AIF1	AIF1 Entrez, Source	allograft inflammatory factor 1	7500	-0.007	0.0162	No
114	RPL22	RPL22 Entrez, Source	ribosomal protein L22	7541	-0.008	0.0135	No
115	AKAP9	AKAP9 Entrez, Source	A kinase (PRKA) anchor protein (yotiao) 9	7704	-0.010	0.0015	No
116	IRF7	IRF7 Entrez, Source	interferon regulatory factor 7	7849	-0.013	-0.0089	No
117	PSME2	PSME2 Entrez, Source	proteasome (prosome, macropain) activator subunit 2 (PA28 beta)	7999	-0.015	-0.0197	No
118	RPS6KC1	RPS6KC1 Entrez, Source	ribosomal protein S6 kinase, 52kDa, polypeptide 1	8055	-0.016	-0.0233	No
119	RETSAT	RETSAT Entrez, Source	retinol saturase (all-trans-retinol 13,14-reductase)	8072	-0.016	-0.0239	No
120	ITGB2	ITGB2 Entrez, Source	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	8281	-0.020	-0.0390	No
121	CDC5L	CDC5L Entrez, Source	CDC5 cell division cycle 5-like (S. pombe)	8386	-0.021	-0.0461	No
122	PLK1	PLK1 Entrez, Source	polo-like kinase 1 (Drosophila)	8736	-0.027	-0.0716	No
123	POM121	POM121 Entrez, Source	POM121 membrane glycoprotein (rat)	8946	-0.031	-0.0864	No
124	IRGM	IRGM Entrez, Source	immunity-related GTPase family, M	8948	-0.031	-0.0853	No
125	VEGFB	VEGFB Entrez, Source	vascular endothelial growth factor B	8955	-0.031	-0.0846	No
126	CYP7B1	CYP7B1 Entrez, Source	cytochrome P450, family 7, subfamily B, polypeptide 1	9114	-0.034	-0.0954	No
127	CAMP	CAMP Entrez, Source	cathelicidin antimicrobial peptide	9148	-0.035	-0.0966	No
128	NCOA3	NCOA3 Entrez, Source	nuclear receptor coactivator 3	9534	-0.042	-0.1243	No
129	CDC91L1	CDC91L1 Entrez, Source	CDC91 cell division cycle 91-like 1 (S. cerevisiae)	9548	-0.043	-0.1237	No
130	FLOT1	FLOT1 Entrez, Source	flotillin 1	9713	-0.046	-0.1345	No
131	MUP5			9782	-0.047	-0.1379	No
132	NR2F6	NR2F6 Entrez, Source	nuclear receptor subfamily 2, group F, member 6	9842	-0.049	-0.1406	No
133	HBA-A1			10085	-0.054	-0.1570	No
134	ATP1B3	ATP1B3 Entrez, Source	ATPase, Na+/K+ transporting, beta 3 polypeptide	10160	-0.056	-0.1606	No
135	PLD3	PLD3 Entrez, Source	phospholipase D family, member 3	10363	-0.061	-0.1737	No
136	PSMB8	PSMB8 Entrez, Source	proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)	10371	-0.061	-0.1720	No
137	TAPBP	TAPBP Entrez, Source	TAP binding protein (tapasin)	10601	-0.067	-0.1869	No
138	ACTL7B	ACTL7B Entrez, Source	actin-like 7B	10635	-0.068	-0.1870	No
139	WARS	WARS Entrez, Source	tryptophanyl-tRNA synthetase	10801	-0.073	-0.1968	No
140	LITAF	LITAF Entrez, Source	lipopolysaccharide-induced TNF factor	10871	-0.074	-0.1993	No
141	LPL	LPL Entrez, Source	lipoprotein lipase	10988	-0.078	-0.2053	No
142	SH3GL1	SH3GL1 Entrez, Source	SH3-domain GRB2-like 1	11182	-0.085	-0.2168	No
143	NRP1	NRP1 Entrez, Source	neuropilin 1	11218	-0.087	-0.2163	No
144	CASP6	CASP6 Entrez, Source	caspase 6, apoptosis-related cysteine peptidase	11468	-0.098	-0.2316	No
145	STX3	STX3 Entrez, Source	syntaxin 3	11595	-0.104	-0.2374	No
146	TMSB10	TMSB10 Entrez, Source	thymosin, beta 10	11750	-0.111	-0.2450	No
147	IFI35	IFI35 Entrez, Source	interferon-induced protein 35	11772	-0.112	-0.2424	No
148	PSMB9	PSMB9 Entrez, Source	proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)	11801	-0.114	-0.2404	No
149	CCL7	CCL7 Entrez, Source	chemokine (C-C motif) ligand 7	11808	-0.114	-0.2367	No
150	KRT1-18			11883	-0.118	-0.2379	No
151	TAP1	TAP1 Entrez, Source	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	12128	-0.133	-0.2516	No
152	BMPR2	BMPR2 Entrez, Source	bone morphogenetic protein receptor, type II (serine/threonine kinase)	12152	-0.135	-0.2484	No
153	QSCN6	QSCN6 Entrez, Source	quiescin Q6	12170	-0.136	-0.2447	No
154	S100A8	S100A8 Entrez, Source	S100 calcium binding protein A8	12223	-0.142	-0.2434	No
155	PTPN1	PTPN1 Entrez, Source	protein tyrosine phosphatase, non-receptor type 1	12267	-0.145	-0.2414	No
156	USP18	USP18 Entrez, Source	ubiquitin specific peptidase 18	12457	-0.165	-0.2497	No
157	LGALS3BP	LGALS3BP Entrez, Source	lectin, galactoside-binding, soluble, 3 binding protein	12495	-0.170	-0.2462	No
158	PPP1R2	PPP1R2 Entrez, Source	protein phosphatase 1, regulatory (inhibitor) subunit 2	12496	-0.170	-0.2400	No
159	BIRC5	BIRC5 Entrez, Source	baculoviral IAP repeat-containing 5 (survivin)	12656	-0.196	-0.2449	No
160	LGMN	LGMN Entrez, Source	legumain	12698	-0.205	-0.2405	No
161	TMSB4X	TMSB4X Entrez, Source	thymosin, beta 4, X-linked	12920	-0.259	-0.2478	No
162	CYBA	CYBA Entrez, Source	cytochrome b-245, alpha polypeptide	12921	-0.260	-0.2382	No
163	COL4A1	COL4A1 Entrez, Source	collagen, type IV, alpha 1	12937	-0.264	-0.2297	No
164	GRN	GRN Entrez, Source	granulin	12966	-0.278	-0.2216	No
165	RELN	RELN Entrez, Source	reelin	12968	-0.279	-0.2114	No
166	TAP2	TAP2 Entrez, Source	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)	13028	-0.306	-0.2047	No
167	LGALS3	LGALS3 Entrez, Source	lectin, galactoside-binding, soluble, 3 (galectin 3)	13064	-0.327	-0.1953	No
168	GPX3	GPX3 Entrez, Source	glutathione peroxidase 3 (plasma)	13095	-0.352	-0.1847	No
169	S100A11	S100A11 Entrez, Source	S100 calcium binding protein A11	13099	-0.355	-0.1719	No
170	AVPR1A	AVPR1A Entrez, Source	arginine vasopressin receptor 1A	13117	-0.366	-0.1597	No
171	PROM1	PROM1 Entrez, Source	prominin 1	13138	-0.389	-0.1469	No
172	OSBPL5	OSBPL5 Entrez, Source	oxysterol binding protein-like 5	13143	-0.394	-0.1327	No
173	S100A6	S100A6 Entrez, Source	S100 calcium binding protein A6	13165	-0.424	-0.1188	No
174	CLIC1	CLIC1 Entrez, Source	chloride intracellular channel 1	13167	-0.426	-0.1032	No
175	S100A4	S100A4 Entrez, Source	S100 calcium binding protein A4	13202	-0.468	-0.0886	No
176	PROCR	PROCR Entrez, Source	protein C receptor, endothelial (EPCR)	13212	-0.481	-0.0716	No
177	GBP2	GBP2 Entrez, Source	guanylate binding protein 2, interferon-inducible	13270	-0.639	-0.0525	No
178	LIPC	LIPC Entrez, Source	lipase, hepatic	13275	-0.650	-0.0289	No
179	CCL2	CCL2 Entrez, Source	chemokine (C-C motif) ligand 2	13317	-0.925	0.0019	No