Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | IDX_TSA_DN_CLUSTER3 |
| Enrichment Score (ES) | -0.5755312 |
| Normalized Enrichment Score (NES) | -1.8157574 |
| Nominal p-value | 0.0017452007 |
| FDR q-value | 0.034382794 |
| FWER p-Value | 0.928 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | VCAM1 | VCAM1 Entrez, Source | vascular cell adhesion molecule 1 | 49 | 0.501 | 0.0545 | No |
| 2 | CXCL12 | CXCL12 Entrez, Source | chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) | 50 | 0.500 | 0.1126 | No |
| 3 | GSTT1 | GSTT1 Entrez, Source | glutathione S-transferase theta 1 | 970 | 0.147 | 0.0606 | No |
| 4 | FADS1 | FADS1 Entrez, Source | fatty acid desaturase 1 | 1495 | 0.114 | 0.0343 | No |
| 5 | TSPYL4 | TSPYL4 Entrez, Source | TSPY-like 4 | 1691 | 0.105 | 0.0319 | No |
| 6 | PHLDA1 | PHLDA1 Entrez, Source | pleckstrin homology-like domain, family A, member 1 | 1708 | 0.105 | 0.0428 | No |
| 7 | PTGS2 | PTGS2 Entrez, Source | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 1781 | 0.102 | 0.0492 | No |
| 8 | GPC4 | GPC4 Entrez, Source | glypican 4 | 1941 | 0.096 | 0.0484 | No |
| 9 | CEBPD | CEBPD Entrez, Source | CCAAT/enhancer binding protein (C/EBP), delta | 2567 | 0.078 | 0.0104 | No |
| 10 | MAOA | MAOA Entrez, Source | monoamine oxidase A | 3427 | 0.057 | -0.0476 | No |
| 11 | EPHX1 | EPHX1 Entrez, Source | epoxide hydrolase 1, microsomal (xenobiotic) | 4104 | 0.045 | -0.0933 | No |
| 12 | SPP1 | SPP1 Entrez, Source | secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) | 4327 | 0.041 | -0.1053 | No |
| 13 | AKAP12 | AKAP12 Entrez, Source | A kinase (PRKA) anchor protein (gravin) 12 | 5319 | 0.024 | -0.1771 | No |
| 14 | IFI30 | IFI30 Entrez, Source | interferon, gamma-inducible protein 30 | 5860 | 0.016 | -0.2158 | No |
| 15 | CSF1 | CSF1 Entrez, Source | colony stimulating factor 1 (macrophage) | 5899 | 0.016 | -0.2169 | No |
| 16 | GGTA1 | GGTA1 Entrez, Source | glycoprotein, alpha-galactosyltransferase 1 | 5999 | 0.014 | -0.2227 | No |
| 17 | SLC8A1 | SLC8A1 Entrez, Source | solute carrier family 8 (sodium/calcium exchanger), member 1 | 6047 | 0.014 | -0.2246 | No |
| 18 | THBS2 | THBS2 Entrez, Source | thrombospondin 2 | 6709 | 0.004 | -0.2740 | No |
| 19 | CDKN2A | CDKN2A Entrez, Source | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 6755 | 0.003 | -0.2770 | No |
| 20 | CCT3 | CCT3 Entrez, Source | chaperonin containing TCP1, subunit 3 (gamma) | 7557 | -0.008 | -0.3363 | No |
| 21 | SKAP2 | SKAP2 Entrez, Source | src kinase associated phosphoprotein 2 | 7850 | -0.013 | -0.3568 | No |
| 22 | ACVR2A | ACVR2A Entrez, Source | activin A receptor, type IIA | 7984 | -0.015 | -0.3651 | No |
| 23 | DNM1 | DNM1 Entrez, Source | dynamin 1 | 8489 | -0.023 | -0.4004 | No |
| 24 | EIF4B | EIF4B Entrez, Source | eukaryotic translation initiation factor 4B | 8550 | -0.024 | -0.4021 | No |
| 25 | SFRP2 | SFRP2 Entrez, Source | secreted frizzled-related protein 2 | 9201 | -0.036 | -0.4469 | No |
| 26 | SPG20 | SPG20 Entrez, Source | spastic paraplegia 20, spartin (Troyer syndrome) | 9547 | -0.043 | -0.4679 | No |
| 27 | RASSF5 | RASSF5 Entrez, Source | Ras association (RalGDS/AF-6) domain family 5 | 9803 | -0.048 | -0.4815 | No |
| 28 | KLF4 | KLF4 Entrez, Source | Kruppel-like factor 4 (gut) | 9940 | -0.051 | -0.4859 | No |
| 29 | ANXA11 | ANXA11 Entrez, Source | annexin A11 | 10458 | -0.063 | -0.5174 | No |
| 30 | STXBP3 | STXBP3 Entrez, Source | syntaxin binding protein 3 | 10515 | -0.064 | -0.5142 | No |
| 31 | CDKN2B | CDKN2B Entrez, Source | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) | 10726 | -0.071 | -0.5218 | No |
| 32 | CSRP1 | CSRP1 Entrez, Source | cysteine and glycine-rich protein 1 | 11225 | -0.087 | -0.5492 | No |
| 33 | SIRT2 | SIRT2 Entrez, Source | sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae) | 11576 | -0.103 | -0.5636 | Yes |
| 34 | PLK2 | PLK2 Entrez, Source | polo-like kinase 2 (Drosophila) | 11671 | -0.108 | -0.5581 | Yes |
| 35 | CNN3 | CNN3 Entrez, Source | calponin 3, acidic | 11730 | -0.111 | -0.5497 | Yes |
| 36 | MAGED2 | MAGED2 Entrez, Source | melanoma antigen family D, 2 | 11818 | -0.115 | -0.5429 | Yes |
| 37 | NEDD9 | NEDD9 Entrez, Source | neural precursor cell expressed, developmentally down-regulated 9 | 11950 | -0.122 | -0.5386 | Yes |
| 38 | EXOC4 | EXOC4 Entrez, Source | exocyst complex component 4 | 11969 | -0.123 | -0.5257 | Yes |
| 39 | JUP | JUP Entrez, Source | junction plakoglobin | 12003 | -0.125 | -0.5136 | Yes |
| 40 | BCAR1 | BCAR1 Entrez, Source | breast cancer anti-estrogen resistance 1 | 12011 | -0.126 | -0.4995 | Yes |
| 41 | PRKCD | PRKCD Entrez, Source | protein kinase C, delta | 12254 | -0.144 | -0.5010 | Yes |
| 42 | NDRG4 | NDRG4 Entrez, Source | NDRG family member 4 | 12261 | -0.145 | -0.4847 | Yes |
| 43 | CYR61 | CYR61 Entrez, Source | cysteine-rich, angiogenic inducer, 61 | 12269 | -0.146 | -0.4683 | Yes |
| 44 | CDK4 | CDK4 Entrez, Source | cyclin-dependent kinase 4 | 12272 | -0.146 | -0.4515 | Yes |
| 45 | PLA2G4A | PLA2G4A Entrez, Source | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 12414 | -0.160 | -0.4435 | Yes |
| 46 | ARMCX2 | ARMCX2 Entrez, Source | armadillo repeat containing, X-linked 2 | 12467 | -0.166 | -0.4282 | Yes |
| 47 | PSCD3 | PSCD3 Entrez, Source | pleckstrin homology, Sec7 and coiled-coil domains 3 | 12480 | -0.168 | -0.4096 | Yes |
| 48 | PLEKHC1 | PLEKHC1 Entrez, Source | pleckstrin homology domain containing, family C (with FERM domain) member 1 | 12574 | -0.181 | -0.3957 | Yes |
| 49 | FZD2 | FZD2 Entrez, Source | frizzled homolog 2 (Drosophila) | 12634 | -0.191 | -0.3779 | Yes |
| 50 | DDAH2 | DDAH2 Entrez, Source | dimethylarginine dimethylaminohydrolase 2 | 12900 | -0.253 | -0.3684 | Yes |
| 51 | DOK1 | DOK1 Entrez, Source | docking protein 1, 62kDa (downstream of tyrosine kinase 1) | 12904 | -0.254 | -0.3392 | Yes |
| 52 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 13011 | -0.297 | -0.3127 | Yes |
| 53 | ROCK2 | ROCK2 Entrez, Source | Rho-associated, coiled-coil containing protein kinase 2 | 13035 | -0.310 | -0.2783 | Yes |
| 54 | DPP7 | DPP7 Entrez, Source | dipeptidyl-peptidase 7 | 13124 | -0.377 | -0.2411 | Yes |
| 55 | PLAT | PLAT Entrez, Source | plasminogen activator, tissue | 13198 | -0.463 | -0.1929 | Yes |
| 56 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 13204 | -0.471 | -0.1385 | Yes |
| 57 | CITED2 | CITED2 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 13211 | -0.481 | -0.0831 | Yes |
| 58 | F3 | F3 Entrez, Source | coagulation factor III (thromboplastin, tissue factor) | 13308 | -0.800 | 0.0026 | Yes |
