Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | IDX_TSA_UP_CLUSTER6 |
| Enrichment Score (ES) | 0.50079334 |
| Normalized Enrichment Score (NES) | 1.9206735 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.006107109 |
| FWER p-Value | 0.364 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | G0S2 | G0S2 Entrez, Source | G0/G1switch 2 | 66 | 0.461 | 0.0360 | Yes |
| 2 | FASN | FASN Entrez, Source | fatty acid synthase | 101 | 0.417 | 0.0706 | Yes |
| 3 | ACAA2 | ACAA2 Entrez, Source | acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase) | 135 | 0.374 | 0.1015 | Yes |
| 4 | FAH | FAH Entrez, Source | fumarylacetoacetate hydrolase (fumarylacetoacetase) | 219 | 0.299 | 0.1219 | Yes |
| 5 | CAT | CAT Entrez, Source | catalase | 290 | 0.269 | 0.1405 | Yes |
| 6 | GPD1 | GPD1 Entrez, Source | glycerol-3-phosphate dehydrogenase 1 (soluble) | 296 | 0.267 | 0.1639 | Yes |
| 7 | REEP6 | REEP6 Entrez, Source | receptor accessory protein 6 | 347 | 0.249 | 0.1824 | Yes |
| 8 | ABCA1 | ABCA1 Entrez, Source | ATP-binding cassette, sub-family A (ABC1), member 1 | 355 | 0.248 | 0.2039 | Yes |
| 9 | HSD11B1 | HSD11B1 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 1 | 370 | 0.242 | 0.2244 | Yes |
| 10 | SLC25A10 | SLC25A10 Entrez, Source | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 | 378 | 0.240 | 0.2452 | Yes |
| 11 | TST | TST Entrez, Source | thiosulfate sulfurtransferase (rhodanese) | 388 | 0.235 | 0.2655 | Yes |
| 12 | ALAS1 | ALAS1 Entrez, Source | aminolevulinate, delta-, synthase 1 | 419 | 0.224 | 0.2832 | Yes |
| 13 | MCCC1 | MCCC1 Entrez, Source | methylcrotonoyl-Coenzyme A carboxylase 1 (alpha) | 556 | 0.192 | 0.2900 | Yes |
| 14 | PDHB | PDHB Entrez, Source | pyruvate dehydrogenase (lipoamide) beta | 563 | 0.190 | 0.3065 | Yes |
| 15 | NR1H3 | NR1H3 Entrez, Source | nuclear receptor subfamily 1, group H, member 3 | 583 | 0.188 | 0.3218 | Yes |
| 16 | ETFDH | ETFDH Entrez, Source | electron-transferring-flavoprotein dehydrogenase | 603 | 0.186 | 0.3369 | Yes |
| 17 | CYB5B | CYB5B Entrez, Source | cytochrome b5 type B (outer mitochondrial membrane) | 632 | 0.182 | 0.3510 | Yes |
| 18 | BCKDHB | BCKDHB Entrez, Source | branched chain keto acid dehydrogenase E1, beta polypeptide (maple syrup urine disease) | 651 | 0.179 | 0.3656 | Yes |
| 19 | DHCR7 | DHCR7 Entrez, Source | 7-dehydrocholesterol reductase | 693 | 0.174 | 0.3780 | Yes |
| 20 | MGLL | MGLL Entrez, Source | monoglyceride lipase | 754 | 0.167 | 0.3883 | Yes |
| 21 | CHPT1 | CHPT1 Entrez, Source | choline phosphotransferase 1 | 778 | 0.165 | 0.4012 | Yes |
| 22 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 800 | 0.163 | 0.4141 | Yes |
| 23 | ALAD | ALAD Entrez, Source | aminolevulinate, delta-, dehydratase | 826 | 0.160 | 0.4265 | Yes |
| 24 | HBLD2 | HBLD2 Entrez, Source | HESB like domain containing 2 | 1036 | 0.141 | 0.4233 | Yes |
| 25 | LIAS | LIAS Entrez, Source | lipoic acid synthetase | 1236 | 0.127 | 0.4196 | Yes |
| 26 | MOSC2 | MOSC2 Entrez, Source | MOCO sulphurase C-terminal domain containing 2 | 1286 | 0.125 | 0.4271 | Yes |
| 27 | ATP5O | ATP5O Entrez, Source | ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein) | 1360 | 0.121 | 0.4323 | Yes |
| 28 | HIBADH | HIBADH Entrez, Source | 3-hydroxyisobutyrate dehydrogenase | 1384 | 0.120 | 0.4412 | Yes |
| 29 | RARRES2 | RARRES2 Entrez, Source | retinoic acid receptor responder (tazarotene induced) 2 | 1501 | 0.113 | 0.4425 | Yes |
| 30 | QDPR | QDPR Entrez, Source | quinoid dihydropteridine reductase | 1560 | 0.110 | 0.4480 | Yes |
| 31 | DECR1 | DECR1 Entrez, Source | 2,4-dienoyl CoA reductase 1, mitochondrial | 1588 | 0.109 | 0.4557 | Yes |
| 32 | HADH | HADH Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase | 1622 | 0.108 | 0.4628 | Yes |
| 33 | SCP2 | SCP2 Entrez, Source | sterol carrier protein 2 | 1632 | 0.107 | 0.4717 | Yes |
| 34 | ACAD9 | ACAD9 Entrez, Source | acyl-Coenzyme A dehydrogenase family, member 9 | 1702 | 0.105 | 0.4758 | Yes |
| 35 | NDUFS1 | NDUFS1 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) | 1817 | 0.101 | 0.4762 | Yes |
| 36 | PEX19 | PEX19 Entrez, Source | peroxisomal biogenesis factor 19 | 1878 | 0.098 | 0.4804 | Yes |
| 37 | ABCD2 | ABCD2 Entrez, Source | ATP-binding cassette, sub-family D (ALD), member 2 | 1926 | 0.096 | 0.4854 | Yes |
| 38 | PGM1 | PGM1 Entrez, Source | phosphoglucomutase 1 | 2063 | 0.092 | 0.4834 | Yes |
| 39 | COX7B | COX7B Entrez, Source | cytochrome c oxidase subunit VIIb | 2157 | 0.089 | 0.4843 | Yes |
| 40 | CYB5A | CYB5A Entrez, Source | cytochrome b5 type A (microsomal) | 2179 | 0.089 | 0.4906 | Yes |
| 41 | ISOC1 | ISOC1 Entrez, Source | isochorismatase domain containing 1 | 2314 | 0.085 | 0.4880 | Yes |
| 42 | HP | HP Entrez, Source | haptoglobin | 2321 | 0.084 | 0.4951 | Yes |
| 43 | HIBCH | HIBCH Entrez, Source | 3-hydroxyisobutyryl-Coenzyme A hydrolase | 2392 | 0.083 | 0.4972 | Yes |
| 44 | TKT | TKT Entrez, Source | transketolase (Wernicke-Korsakoff syndrome) | 2441 | 0.081 | 0.5008 | Yes |
| 45 | PLA2G6 | PLA2G6 Entrez, Source | phospholipase A2, group VI (cytosolic, calcium-independent) | 2615 | 0.076 | 0.4945 | No |
| 46 | SDHA | SDHA Entrez, Source | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 2780 | 0.072 | 0.4885 | No |
| 47 | AQP7 | AQP7 Entrez, Source | aquaporin 7 | 2868 | 0.070 | 0.4881 | No |
| 48 | MGST1 | MGST1 Entrez, Source | microsomal glutathione S-transferase 1 | 2888 | 0.069 | 0.4929 | No |
| 49 | SLC25A1 | SLC25A1 Entrez, Source | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 | 2912 | 0.069 | 0.4972 | No |
| 50 | DLD | DLD Entrez, Source | dihydrolipoamide dehydrogenase | 3142 | 0.063 | 0.4856 | No |
| 51 | MPDU1 | MPDU1 Entrez, Source | mannose-P-dolichol utilization defect 1 | 3177 | 0.063 | 0.4886 | No |
| 52 | UQCRC2 | UQCRC2 Entrez, Source | ubiquinol-cytochrome c reductase core protein II | 3187 | 0.063 | 0.4935 | No |
| 53 | NDUFA9 | NDUFA9 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa | 3253 | 0.061 | 0.4940 | No |
| 54 | COX5B | COX5B Entrez, Source | cytochrome c oxidase subunit Vb | 3275 | 0.061 | 0.4978 | No |
| 55 | SLC25A5 | SLC25A5 Entrez, Source | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 3418 | 0.058 | 0.4923 | No |
| 56 | EHD1 | EHD1 Entrez, Source | EH-domain containing 1 | 3447 | 0.057 | 0.4952 | No |
| 57 | GSR | GSR Entrez, Source | glutathione reductase | 3579 | 0.054 | 0.4901 | No |
| 58 | COX7A2 | COX7A2 Entrez, Source | cytochrome c oxidase subunit VIIa polypeptide 2 (liver) | 3681 | 0.052 | 0.4872 | No |
| 59 | UQCRC1 | UQCRC1 Entrez, Source | ubiquinol-cytochrome c reductase core protein I | 3903 | 0.048 | 0.4748 | No |
| 60 | DBT | DBT Entrez, Source | dihydrolipoamide branched chain transacylase E2 | 3912 | 0.048 | 0.4785 | No |
| 61 | CS | CS Entrez, Source | citrate synthase | 4175 | 0.043 | 0.4625 | No |
| 62 | DLST | DLST Entrez, Source | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 4335 | 0.040 | 0.4541 | No |
| 63 | SFXN1 | SFXN1 Entrez, Source | sideroflexin 1 | 4446 | 0.039 | 0.4493 | No |
| 64 | PON2 | PON2 Entrez, Source | paraoxonase 2 | 4640 | 0.035 | 0.4378 | No |
| 65 | HADHB | HADHB Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit | 4675 | 0.035 | 0.4383 | No |
| 66 | SAMM50 | SAMM50 Entrez, Source | sorting and assembly machinery component 50 homolog (S. cerevisiae) | 4790 | 0.033 | 0.4326 | No |
| 67 | ORM1 | ORM1 Entrez, Source | orosomucoid 1 | 4816 | 0.032 | 0.4336 | No |
| 68 | DGAT1 | DGAT1 Entrez, Source | diacylglycerol O-acyltransferase homolog 1 (mouse) | 5118 | 0.027 | 0.4133 | No |
| 69 | GBE1 | GBE1 Entrez, Source | glucan (1,4-alpha-), branching enzyme 1 (glycogen branching enzyme, Andersen disease, glycogen storage disease type IV) | 5119 | 0.027 | 0.4158 | No |
| 70 | UQCRB | UQCRB Entrez, Source | ubiquinol-cytochrome c reductase binding protein | 5231 | 0.026 | 0.4097 | No |
| 71 | ATP5D | ATP5D Entrez, Source | ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit | 5323 | 0.024 | 0.4050 | No |
| 72 | HSD17B12 | HSD17B12 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 12 | 5355 | 0.024 | 0.4047 | No |
| 73 | SUCLG1 | SUCLG1 Entrez, Source | succinate-CoA ligase, GDP-forming, alpha subunit | 5738 | 0.018 | 0.3775 | No |
| 74 | SDHC | SDHC Entrez, Source | succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa | 5789 | 0.018 | 0.3753 | No |
| 75 | ACADL | ACADL Entrez, Source | acyl-Coenzyme A dehydrogenase, long chain | 5812 | 0.017 | 0.3752 | No |
| 76 | ACADS | ACADS Entrez, Source | acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain | 5886 | 0.016 | 0.3711 | No |
| 77 | SLC19A1 | SLC19A1 Entrez, Source | solute carrier family 19 (folate transporter), member 1 | 6886 | 0.002 | 0.2957 | No |
| 78 | CA2 | CA2 Entrez, Source | carbonic anhydrase II | 7159 | -0.002 | 0.2754 | No |
| 79 | NDUFA5 | NDUFA5 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa | 7283 | -0.004 | 0.2665 | No |
| 80 | CIB2 | CIB2 Entrez, Source | calcium and integrin binding family member 2 | 7716 | -0.011 | 0.2348 | No |
| 81 | BNIP3 | BNIP3 Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 3 | 7875 | -0.013 | 0.2240 | No |
| 82 | RETSAT | RETSAT Entrez, Source | retinol saturase (all-trans-retinol 13,14-reductase) | 8072 | -0.016 | 0.2106 | No |
| 83 | LTC4S | LTC4S Entrez, Source | leukotriene C4 synthase | 8127 | -0.017 | 0.2080 | No |
| 84 | PDAP1 | PDAP1 Entrez, Source | PDGFA associated protein 1 | 8543 | -0.024 | 0.1788 | No |
| 85 | TSPAN12 | TSPAN12 Entrez, Source | tetraspanin 12 | 8909 | -0.030 | 0.1539 | No |
| 86 | CAMP | CAMP Entrez, Source | cathelicidin antimicrobial peptide | 9148 | -0.035 | 0.1390 | No |
| 87 | CDKN2C | CDKN2C Entrez, Source | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 9276 | -0.037 | 0.1328 | No |
| 88 | PCYOX1 | PCYOX1 Entrez, Source | prenylcysteine oxidase 1 | 9571 | -0.043 | 0.1144 | No |
| 89 | DHRS7B | DHRS7B Entrez, Source | dehydrogenase/reductase (SDR family) member 7B | 9615 | -0.044 | 0.1150 | No |
| 90 | S100A1 | S100A1 Entrez, Source | S100 calcium binding protein A1 | 9735 | -0.046 | 0.1102 | No |
| 91 | RTN3 | RTN3 Entrez, Source | reticulon 3 | 9786 | -0.048 | 0.1106 | No |
| 92 | SLC2A4 | SLC2A4 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 4 | 9794 | -0.048 | 0.1144 | No |
| 93 | BCAT2 | BCAT2 Entrez, Source | branched chain aminotransferase 2, mitochondrial | 9815 | -0.048 | 0.1172 | No |
| 94 | COL15A1 | COL15A1 Entrez, Source | collagen, type XV, alpha 1 | 10011 | -0.052 | 0.1071 | No |
| 95 | PCAF | PCAF Entrez, Source | p300/CBP-associated factor | 10191 | -0.056 | 0.0986 | No |
| 96 | ADCY6 | ADCY6 Entrez, Source | adenylate cyclase 6 | 10445 | -0.063 | 0.0850 | No |
| 97 | CBR1 | CBR1 Entrez, Source | carbonyl reductase 1 | 10569 | -0.066 | 0.0816 | No |
| 98 | ADIPOQ | ADIPOQ Entrez, Source | adiponectin, C1Q and collagen domain containing | 10637 | -0.068 | 0.0826 | No |
| 99 | PSEN2 | PSEN2 Entrez, Source | presenilin 2 (Alzheimer disease 4) | 10691 | -0.070 | 0.0848 | No |
| 100 | LPL | LPL Entrez, Source | lipoprotein lipase | 10988 | -0.078 | 0.0694 | No |
| 101 | DLAT | DLAT Entrez, Source | dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) | 10995 | -0.078 | 0.0759 | No |
| 102 | RAB3D | RAB3D Entrez, Source | RAB3D, member RAS oncogene family | 11442 | -0.097 | 0.0509 | No |
| 103 | SCARB1 | SCARB1 Entrez, Source | scavenger receptor class B, member 1 | 11498 | -0.099 | 0.0556 | No |
| 104 | SDPR | SDPR Entrez, Source | serum deprivation response (phosphatidylserine binding protein) | 11603 | -0.105 | 0.0570 | No |
| 105 | S100A8 | S100A8 Entrez, Source | S100 calcium binding protein A8 | 12223 | -0.142 | 0.0229 | No |
| 106 | UNC119 | UNC119 Entrez, Source | unc-119 homolog (C. elegans) | 12224 | -0.142 | 0.0355 | No |
| 107 | ITGA6 | ITGA6 Entrez, Source | integrin, alpha 6 | 12855 | -0.239 | 0.0092 | No |
| 108 | LDHB | LDHB Entrez, Source | lactate dehydrogenase B | 13034 | -0.309 | 0.0233 | No |
