Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | IGLESIAS_E2FMINUS_UP |
| Enrichment Score (ES) | -0.50714934 |
| Normalized Enrichment Score (NES) | -1.7856857 |
| Nominal p-value | 0.0016233766 |
| FDR q-value | 0.039321605 |
| FWER p-Value | 0.987 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CDO1 | CDO1 Entrez, Source | cysteine dioxygenase, type I | 58 | 0.484 | 0.0278 | No |
| 2 | ENPP2 | ENPP2 Entrez, Source | ectonucleotide pyrophosphatase/phosphodiesterase 2 (autotaxin) | 143 | 0.363 | 0.0456 | No |
| 3 | C1QB | C1QB Entrez, Source | complement component 1, q subcomponent, B chain | 383 | 0.238 | 0.0434 | No |
| 4 | IGFBP4 | IGFBP4 Entrez, Source | insulin-like growth factor binding protein 4 | 391 | 0.235 | 0.0585 | No |
| 5 | CTSS | CTSS Entrez, Source | cathepsin S | 456 | 0.214 | 0.0679 | No |
| 6 | TYROBP | TYROBP Entrez, Source | TYRO protein tyrosine kinase binding protein | 747 | 0.168 | 0.0571 | No |
| 7 | UGDH | UGDH Entrez, Source | UDP-glucose dehydrogenase | 951 | 0.149 | 0.0517 | No |
| 8 | CFD | CFD Entrez, Source | complement factor D (adipsin) | 1087 | 0.138 | 0.0507 | No |
| 9 | CES3 | CES3 Entrez, Source | carboxylesterase 3 (brain) | 1183 | 0.131 | 0.0522 | No |
| 10 | RBP1 | RBP1 Entrez, Source | retinol binding protein 1, cellular | 1390 | 0.119 | 0.0446 | No |
| 11 | C3 | C3 Entrez, Source | complement component 3 | 1475 | 0.114 | 0.0458 | No |
| 12 | COL1A1 | COL1A1 Entrez, Source | collagen, type I, alpha 1 | 1619 | 0.108 | 0.0422 | No |
| 13 | CTSE | CTSE Entrez, Source | cathepsin E | 1718 | 0.104 | 0.0417 | No |
| 14 | GADD45B | GADD45B Entrez, Source | growth arrest and DNA-damage-inducible, beta | 1856 | 0.099 | 0.0380 | No |
| 15 | NID2 | NID2 Entrez, Source | nidogen 2 (osteonidogen) | 1863 | 0.099 | 0.0441 | No |
| 16 | LYL1 | LYL1 Entrez, Source | lymphoblastic leukemia derived sequence 1 | 1977 | 0.095 | 0.0419 | No |
| 17 | NFKBIA | NFKBIA Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 2241 | 0.087 | 0.0278 | No |
| 18 | LGALS1 | LGALS1 Entrez, Source | lectin, galactoside-binding, soluble, 1 (galectin 1) | 2281 | 0.086 | 0.0305 | No |
| 19 | SERPINF1 | SERPINF1 Entrez, Source | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 2345 | 0.084 | 0.0314 | No |
| 20 | CD53 | CD53 Entrez, Source | CD53 molecule | 2467 | 0.081 | 0.0276 | No |
| 21 | APLP2 | APLP2 Entrez, Source | amyloid beta (A4) precursor-like protein 2 | 2711 | 0.073 | 0.0141 | No |
| 22 | RHOB | RHOB Entrez, Source | ras homolog gene family, member B | 2800 | 0.071 | 0.0122 | No |
| 23 | ELN | ELN Entrez, Source | elastin (supravalvular aortic stenosis, Williams-Beuren syndrome) | 2811 | 0.071 | 0.0162 | No |
| 24 | CLK1 | CLK1 Entrez, Source | CDC-like kinase 1 | 2848 | 0.070 | 0.0181 | No |
| 25 | COL6A2 | COL6A2 Entrez, Source | collagen, type VI, alpha 2 | 2971 | 0.067 | 0.0134 | No |
| 26 | IGFBP5 | IGFBP5 Entrez, Source | insulin-like growth factor binding protein 5 | 4057 | 0.045 | -0.0656 | No |
| 27 | ACADM | ACADM Entrez, Source | acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain | 4299 | 0.041 | -0.0811 | No |
| 28 | ARSA | ARSA Entrez, Source | arylsulfatase A | 4628 | 0.036 | -0.1035 | No |
| 29 | GAS6 | GAS6 Entrez, Source | growth arrest-specific 6 | 4656 | 0.035 | -0.1032 | No |
| 30 | LAPTM5 | LAPTM5 Entrez, Source | lysosomal associated multispanning membrane protein 5 | 4666 | 0.035 | -0.1015 | No |
| 31 | CD9 | CD9 Entrez, Source | CD9 molecule | 4896 | 0.031 | -0.1168 | No |
| 32 | FMO1 | FMO1 Entrez, Source | flavin containing monooxygenase 1 | 5137 | 0.027 | -0.1331 | No |
| 33 | CACYBP | CACYBP Entrez, Source | calcyclin binding protein | 5309 | 0.025 | -0.1444 | No |
| 34 | SPARC | SPARC Entrez, Source | secreted protein, acidic, cysteine-rich (osteonectin) | 5548 | 0.021 | -0.1610 | No |
| 35 | ALAS2 | ALAS2 Entrez, Source | aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia) | 5606 | 0.020 | -0.1639 | No |
| 36 | ACADL | ACADL Entrez, Source | acyl-Coenzyme A dehydrogenase, long chain | 5812 | 0.017 | -0.1783 | No |
| 37 | EVL | EVL Entrez, Source | Enah/Vasp-like | 5854 | 0.016 | -0.1803 | No |
| 38 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 5968 | 0.015 | -0.1879 | No |
| 39 | GJA1 | GJA1 Entrez, Source | gap junction protein, alpha 1, 43kDa (connexin 43) | 6120 | 0.013 | -0.1984 | No |
| 40 | RPS14 | RPS14 Entrez, Source | ribosomal protein S14 | 6720 | 0.004 | -0.2434 | No |
| 41 | ID2 | ID2 Entrez, Source | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 6773 | 0.003 | -0.2472 | No |
| 42 | APOE | APOE Entrez, Source | apolipoprotein E | 6859 | 0.002 | -0.2535 | No |
| 43 | SKP1A | SKP1A Entrez, Source | S-phase kinase-associated protein 1A (p19A) | 7418 | -0.006 | -0.2952 | No |
| 44 | NID1 | NID1 Entrez, Source | nidogen 1 | 7761 | -0.011 | -0.3203 | No |
| 45 | COL1A2 | COL1A2 Entrez, Source | collagen, type I, alpha 2 | 8051 | -0.016 | -0.3411 | No |
| 46 | CTSZ | CTSZ Entrez, Source | cathepsin Z | 8078 | -0.016 | -0.3420 | No |
| 47 | TIMM22 | TIMM22 Entrez, Source | translocase of inner mitochondrial membrane 22 homolog (yeast) | 8179 | -0.018 | -0.3484 | No |
| 48 | COL18A1 | COL18A1 Entrez, Source | collagen, type XVIII, alpha 1 | 8284 | -0.020 | -0.3550 | No |
| 49 | PMP22 | PMP22 Entrez, Source | peripheral myelin protein 22 | 8539 | -0.024 | -0.3726 | No |
| 50 | DCN | DCN Entrez, Source | decorin | 8600 | -0.025 | -0.3755 | No |
| 51 | DNAJA1 | DNAJA1 Entrez, Source | DnaJ (Hsp40) homolog, subfamily A, member 1 | 9325 | -0.038 | -0.4276 | No |
| 52 | MORF4L1 | MORF4L1 Entrez, Source | mortality factor 4 like 1 | 9516 | -0.042 | -0.4392 | No |
| 53 | SCG2 | SCG2 Entrez, Source | secretogranin II (chromogranin C) | 9523 | -0.042 | -0.4368 | No |
| 54 | CDC42 | CDC42 Entrez, Source | cell division cycle 42 (GTP binding protein, 25kDa) | 9556 | -0.043 | -0.4364 | No |
| 55 | BAX | BAX Entrez, Source | BCL2-associated X protein | 9773 | -0.047 | -0.4496 | No |
| 56 | B2M | B2M Entrez, Source | beta-2-microglobulin | 9941 | -0.051 | -0.4588 | No |
| 57 | CDKN1C | CDKN1C Entrez, Source | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 10008 | -0.052 | -0.4603 | No |
| 58 | COL15A1 | COL15A1 Entrez, Source | collagen, type XV, alpha 1 | 10011 | -0.052 | -0.4570 | No |
| 59 | BZW1 | BZW1 Entrez, Source | basic leucine zipper and W2 domains 1 | 10041 | -0.053 | -0.4557 | No |
| 60 | HBA-A1 | 10085 | -0.054 | -0.4553 | No | ||
| 61 | CAPZA2 | CAPZA2 Entrez, Source | capping protein (actin filament) muscle Z-line, alpha 2 | 10153 | -0.056 | -0.4567 | No |
| 62 | ITM2B | ITM2B Entrez, Source | integral membrane protein 2B | 10579 | -0.066 | -0.4844 | No |
| 63 | SEPT2 | SEPT2 Entrez, Source | septin 2 | 10614 | -0.067 | -0.4825 | No |
| 64 | ADIPOQ | ADIPOQ Entrez, Source | adiponectin, C1Q and collagen domain containing | 10637 | -0.068 | -0.4796 | No |
| 65 | SMAD1 | SMAD1 Entrez, Source | SMAD, mothers against DPP homolog 1 (Drosophila) | 10761 | -0.072 | -0.4842 | No |
| 66 | LPL | LPL Entrez, Source | lipoprotein lipase | 10988 | -0.078 | -0.4960 | No |
| 67 | NFIB | NFIB Entrez, Source | nuclear factor I/B | 11136 | -0.083 | -0.5016 | Yes |
| 68 | CCNG1 | CCNG1 Entrez, Source | cyclin G1 | 11138 | -0.083 | -0.4961 | Yes |
| 69 | SS18 | SS18 Entrez, Source | synovial sarcoma translocation, chromosome 18 | 11166 | -0.084 | -0.4926 | Yes |
| 70 | CSRP1 | CSRP1 Entrez, Source | cysteine and glycine-rich protein 1 | 11225 | -0.087 | -0.4912 | Yes |
| 71 | FBLN2 | FBLN2 Entrez, Source | fibulin 2 | 11361 | -0.093 | -0.4952 | Yes |
| 72 | NPTN | NPTN Entrez, Source | neuroplastin | 11383 | -0.094 | -0.4905 | Yes |
| 73 | ITGB1 | ITGB1 Entrez, Source | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 11396 | -0.095 | -0.4851 | Yes |
| 74 | RBBP7 | RBBP7 Entrez, Source | retinoblastoma binding protein 7 | 11453 | -0.098 | -0.4829 | Yes |
| 75 | IGSF4 | IGSF4 Entrez, Source | immunoglobulin superfamily, member 4 | 11649 | -0.107 | -0.4905 | Yes |
| 76 | CNN3 | CNN3 Entrez, Source | calponin 3, acidic | 11730 | -0.111 | -0.4892 | Yes |
| 77 | LUM | LUM Entrez, Source | lumican | 11773 | -0.112 | -0.4849 | Yes |
| 78 | COL5A2 | COL5A2 Entrez, Source | collagen, type V, alpha 2 | 12008 | -0.126 | -0.4942 | Yes |
| 79 | LMNA | LMNA Entrez, Source | lamin A/C | 12083 | -0.130 | -0.4911 | Yes |
| 80 | ANGPTL2 | ANGPTL2 Entrez, Source | angiopoietin-like 2 | 12092 | -0.131 | -0.4831 | Yes |
| 81 | GNB1 | GNB1 Entrez, Source | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 12099 | -0.132 | -0.4748 | Yes |
| 82 | S100A10 | S100A10 Entrez, Source | S100 calcium binding protein A10 | 12310 | -0.149 | -0.4807 | Yes |
| 83 | CALM2 | CALM2 Entrez, Source | calmodulin 2 (phosphorylase kinase, delta) | 12340 | -0.152 | -0.4728 | Yes |
| 84 | GSN | GSN Entrez, Source | gelsolin (amyloidosis, Finnish type) | 12398 | -0.157 | -0.4666 | Yes |
| 85 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 12413 | -0.160 | -0.4570 | Yes |
| 86 | GNAI2 | GNAI2 Entrez, Source | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | 12486 | -0.168 | -0.4513 | Yes |
| 87 | LAPTM4A | LAPTM4A Entrez, Source | lysosomal-associated protein transmembrane 4 alpha | 12535 | -0.176 | -0.4432 | Yes |
| 88 | ACTA2 | ACTA2 Entrez, Source | actin, alpha 2, smooth muscle, aorta | 12537 | -0.177 | -0.4316 | Yes |
| 89 | COL3A1 | COL3A1 Entrez, Source | collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) | 12541 | -0.177 | -0.4200 | Yes |
| 90 | ANXA2 | ANXA2 Entrez, Source | annexin A2 | 12661 | -0.197 | -0.4159 | Yes |
| 91 | CD47 | CD47 Entrez, Source | CD47 molecule | 12700 | -0.205 | -0.4051 | Yes |
| 92 | SLC25A4 | SLC25A4 Entrez, Source | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 | 12710 | -0.207 | -0.3921 | Yes |
| 93 | DSTN | DSTN Entrez, Source | destrin (actin depolymerizing factor) | 12715 | -0.208 | -0.3785 | Yes |
| 94 | TMSB4X | TMSB4X Entrez, Source | thymosin, beta 4, X-linked | 12920 | -0.259 | -0.3767 | Yes |
| 95 | COL4A1 | COL4A1 Entrez, Source | collagen, type IV, alpha 1 | 12937 | -0.264 | -0.3603 | Yes |
| 96 | TUBB | TUBB Entrez, Source | tubulin, beta | 13001 | -0.292 | -0.3456 | Yes |
| 97 | ANXA3 | ANXA3 Entrez, Source | annexin A3 | 13069 | -0.331 | -0.3287 | Yes |
| 98 | CCND2 | CCND2 Entrez, Source | cyclin D2 | 13080 | -0.340 | -0.3068 | Yes |
| 99 | S100A11 | S100A11 Entrez, Source | S100 calcium binding protein A11 | 13099 | -0.355 | -0.2846 | Yes |
| 100 | EMP1 | EMP1 Entrez, Source | epithelial membrane protein 1 | 13109 | -0.363 | -0.2611 | Yes |
| 101 | DAB2 | DAB2 Entrez, Source | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) | 13152 | -0.403 | -0.2375 | Yes |
| 102 | S100A6 | S100A6 Entrez, Source | S100 calcium binding protein A6 | 13165 | -0.424 | -0.2102 | Yes |
| 103 | LCP1 | LCP1 Entrez, Source | lymphocyte cytosolic protein 1 (L-plastin) | 13166 | -0.425 | -0.1819 | Yes |
| 104 | SERPINB6A | 13196 | -0.459 | -0.1536 | Yes | ||
| 105 | KITLG | KITLG Entrez, Source | KIT ligand | 13215 | -0.492 | -0.1222 | Yes |
| 106 | SERPINH1 | SERPINH1 Entrez, Source | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | 13290 | -0.708 | -0.0807 | Yes |
| 107 | ANXA1 | ANXA1 Entrez, Source | annexin A1 | 13336 | -1.272 | 0.0005 | Yes |
