Details for gene set INSULIN

Table: GSEA Results Summary

Dataset	double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos
Phenotype	class.cls#double_gel_72h_versus_single_gel_72h_repos
Upregulated in class	double_gel_72h
GeneSet	INSULIN_SIGNALING
Enrichment Score (ES)	0.4105611
Normalized Enrichment Score (NES)	1.4954839
Nominal p-value	0.021791767
FDR q-value	0.122956485
FWER p-Value	1.0

Table: GSEA details [plain text format]
	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	FOS	FOS Entrez, Source	v-fos FBJ murine osteosarcoma viral oncogene homolog	0	1.284	0.1209	Yes
2	PKLR	PKLR Entrez, Source	pyruvate kinase, liver and RBC	31	0.561	0.1714	Yes
3	FBP1	FBP1 Entrez, Source	fructose-1,6-bisphosphatase 1	43	0.515	0.2191	Yes
4	G6PC	G6PC Entrez, Source	glucose-6-phosphatase, catalytic subunit	129	0.383	0.2488	Yes
5	GCK	GCK Entrez, Source	glucokinase (hexokinase 4, maturity onset diabetes of the young 2)	140	0.368	0.2826	Yes
6	CEBPA	CEBPA Entrez, Source	CCAAT/enhancer binding protein (C/EBP), alpha	203	0.308	0.3069	Yes
7	ACACA	ACACA Entrez, Source	acetyl-Coenzyme A carboxylase alpha	231	0.293	0.3325	Yes
8	ACOX1	ACOX1 Entrez, Source	acyl-Coenzyme A oxidase 1, palmitoyl	266	0.281	0.3563	Yes
9	SREBF1	SREBF1 Entrez, Source	sterol regulatory element binding transcription factor 1	310	0.264	0.3779	Yes
10	IGFBP1	IGFBP1 Entrez, Source	insulin-like growth factor binding protein 1	703	0.173	0.3646	Yes
11	INSR	INSR Entrez, Source	insulin receptor	735	0.169	0.3782	Yes
12	ACACB	ACACB Entrez, Source	acetyl-Coenzyme A carboxylase beta	742	0.168	0.3935	Yes
13	CEBPB	CEBPB Entrez, Source	CCAAT/enhancer binding protein (C/EBP), beta	884	0.154	0.3974	Yes
14	VEGF	VEGF Entrez, Source	vascular endothelial growth factor	901	0.153	0.4106	Yes
15	LDLR	LDLR Entrez, Source	low density lipoprotein receptor (familial hypercholesterolemia)	1160	0.133	0.4036	No
16	SHC1	SHC1 Entrez, Source	SHC (Src homology 2 domain containing) transforming protein 1	1997	0.094	0.3495	No
17	EIF2B1	EIF2B1 Entrez, Source	eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa	2303	0.085	0.3345	No
18	IRS1	IRS1 Entrez, Source	insulin receptor substrate 1	2329	0.084	0.3405	No
19	PRKCB1	PRKCB1 Entrez, Source	protein kinase C, beta 1	2401	0.082	0.3429	No
20	TG	TG Entrez, Source	thyroglobulin	2956	0.067	0.3075	No
21	AKT2	AKT2 Entrez, Source	v-akt murine thymoma viral oncogene homolog 2	3361	0.059	0.2826	No
22	HK2	HK2 Entrez, Source	hexokinase 2	3553	0.055	0.2733	No
23	PPARG	PPARG Entrez, Source	peroxisome proliferative activated receptor, gamma	3592	0.054	0.2756	No
24	RPS6KB1	RPS6KB1 Entrez, Source	ribosomal protein S6 kinase, 70kDa, polypeptide 1	3665	0.053	0.2751	No
25	RAF1	RAF1 Entrez, Source	v-raf-1 murine leukemia viral oncogene homolog 1	3941	0.048	0.2588	No
26	PRKCZ	PRKCZ Entrez, Source	protein kinase C, zeta	4083	0.045	0.2524	No
27	PIK3R1	PIK3R1 Entrez, Source	phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha)	4760	0.033	0.2046	No
28	ORM1	ORM1 Entrez, Source	orosomucoid 1	4816	0.032	0.2035	No
29	HRAS	HRAS Entrez, Source	v-Ha-ras Harvey rat sarcoma viral oncogene homolog	4923	0.030	0.1983	No
30	ADRB3	ADRB3 Entrez, Source	adrenergic, beta-3-, receptor	5121	0.027	0.1861	No
31	BRAF	BRAF Entrez, Source	v-raf murine sarcoma viral oncogene homolog B1	5266	0.025	0.1776	No
32	GSK3A	GSK3A Entrez, Source	glycogen synthase kinase 3 alpha	5399	0.023	0.1698	No
33	RPS6KA1	RPS6KA1 Entrez, Source	ribosomal protein S6 kinase, 90kDa, polypeptide 1	5488	0.022	0.1652	No
34	GRB2	GRB2 Entrez, Source	growth factor receptor-bound protein 2	6191	0.011	0.1134	No
35	PIK3R2	PIK3R2 Entrez, Source	phosphoinositide-3-kinase, regulatory subunit 2 (p85 beta)	6361	0.009	0.1015	No
36	UCP1	UCP1 Entrez, Source	uncoupling protein 1 (mitochondrial, proton carrier)	6421	0.007	0.0977	No
37	EIF4E	EIF4E Entrez, Source	eukaryotic translation initiation factor 4E	6703	0.004	0.0769	No
38	EIF4EBP1	EIF4EBP1 Entrez, Source	eukaryotic translation initiation factor 4E binding protein 1	6950	0.000	0.0584	No
39	PDPK1	PDPK1 Entrez, Source	3-phosphoinositide dependent protein kinase-1	7143	-0.002	0.0441	No
40	RPL13A	RPL13A Entrez, Source	ribosomal protein L13a	7446	-0.007	0.0220	No
41	MAP2K2	MAP2K2 Entrez, Source	mitogen-activated protein kinase kinase 2	8062	-0.016	-0.0229	No
42	PTPN11	PTPN11 Entrez, Source	protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1)	8096	-0.016	-0.0239	No
43	FRAP1	FRAP1 Entrez, Source	FK506 binding protein 12-rapamycin associated protein 1	8101	-0.016	-0.0226	No
44	PPIA	PPIA Entrez, Source	peptidylprolyl isomerase A (cyclophilin A)	8225	-0.018	-0.0302	No
45	PIK3CB	PIK3CB Entrez, Source	phosphoinositide-3-kinase, catalytic, beta polypeptide	8414	-0.022	-0.0423	No
46	AKT3	AKT3 Entrez, Source	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	9131	-0.035	-0.0930	No
47	CRK	CRK Entrez, Source	v-crk sarcoma virus CT10 oncogene homolog (avian)	9430	-0.040	-0.1117	No
48	PRL	PRL Entrez, Source	prolactin	9700	-0.046	-0.1277	No
49	MAPK1	MAPK1 Entrez, Source	mitogen-activated protein kinase 1	9755	-0.047	-0.1273	No
50	SLC2A4	SLC2A4 Entrez, Source	solute carrier family 2 (facilitated glucose transporter), member 4	9794	-0.048	-0.1257	No
51	BRD4	BRD4 Entrez, Source	bromodomain containing 4	10182	-0.056	-0.1496	No
52	PPP1CA	PPP1CA Entrez, Source	protein phosphatase 1, catalytic subunit, alpha isoform	10210	-0.057	-0.1463	No
53	CSN2	CSN2 Entrez, Source	casein beta	10559	-0.066	-0.1663	No
54	AKT1	AKT1 Entrez, Source	v-akt murine thymoma viral oncogene homolog 1	10634	-0.068	-0.1655	No
55	BCL2L1	BCL2L1 Entrez, Source	BCL2-like 1	10828	-0.073	-0.1732	No
56	LNPEP	LNPEP Entrez, Source	leucyl/cystinyl aminopeptidase	10866	-0.074	-0.1690	No
57	SOS2	SOS2 Entrez, Source	son of sevenless homolog 2 (Drosophila)	10962	-0.077	-0.1689	No
58	GCG	GCG Entrez, Source	glucagon	11033	-0.080	-0.1666	No
59	MAP2K1	MAP2K1 Entrez, Source	mitogen-activated protein kinase kinase 1	11293	-0.090	-0.1777	No
60	GSK3B	GSK3B Entrez, Source	glycogen synthase kinase 3 beta	11474	-0.098	-0.1820	No
61	LEP	LEP Entrez, Source	leptin (obesity homolog, mouse)	11481	-0.099	-0.1731	No
62	ACTB	ACTB Entrez, Source	actin, beta	11552	-0.102	-0.1688	No
63	PIK3R3	PIK3R3 Entrez, Source	phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma)	11622	-0.106	-0.1641	No
64	JUN	JUN Entrez, Source	jun oncogene	11756	-0.111	-0.1636	No
65	PTPRF	PTPRF Entrez, Source	protein tyrosine phosphatase, receptor type, F	12127	-0.133	-0.1790	No
66	SLC27A4	SLC27A4 Entrez, Source	solute carrier family 27 (fatty acid transporter), member 4	12200	-0.139	-0.1713	No
67	PTPN1	PTPN1 Entrez, Source	protein tyrosine phosphatase, non-receptor type 1	12267	-0.145	-0.1626	No
68	UCP2	UCP2 Entrez, Source	uncoupling protein 2 (mitochondrial, proton carrier)	12505	-0.172	-0.1643	No
69	PIK3CA	PIK3CA Entrez, Source	phosphoinositide-3-kinase, catalytic, alpha polypeptide	12536	-0.176	-0.1500	No
70	PRKCI	PRKCI Entrez, Source	protein kinase C, iota	12716	-0.208	-0.1438	No
71	CAP1	CAP1 Entrez, Source	CAP, adenylate cyclase-associated protein 1 (yeast)	12826	-0.231	-0.1303	No
72	DOK1	DOK1 Entrez, Source	docking protein 1, 62kDa (downstream of tyrosine kinase 1)	12904	-0.254	-0.1122	No
73	SLC2A1	SLC2A1 Entrez, Source	solute carrier family 2 (facilitated glucose transporter), member 1	12962	-0.277	-0.0905	No
74	RRAS2	RRAS2 Entrez, Source	related RAS viral (r-ras) oncogene homolog 2	13055	-0.322	-0.0671	No
75	SERPINE1	SERPINE1 Entrez, Source	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	13125	-0.378	-0.0368	No
76	NPY	NPY Entrez, Source	neuropeptide Y	13255	-0.563	0.0066	No