Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | INTEGRINPATHWAY |
| Enrichment Score (ES) | -0.7534367 |
| Normalized Enrichment Score (NES) | -2.0534174 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0031703778 |
| FWER p-Value | 0.064 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SHC1 | SHC1 Entrez, Source | SHC (Src homology 2 domain containing) transforming protein 1 | 1997 | 0.094 | -0.1287 | No |
| 2 | FYN | FYN Entrez, Source | FYN oncogene related to SRC, FGR, YES | 3374 | 0.059 | -0.2189 | No |
| 3 | RAF1 | RAF1 Entrez, Source | v-raf-1 murine leukemia viral oncogene homolog 1 | 3941 | 0.048 | -0.2506 | No |
| 4 | HRAS | HRAS Entrez, Source | v-Ha-ras Harvey rat sarcoma viral oncogene homolog | 4923 | 0.030 | -0.3175 | No |
| 5 | ITGA1 | ITGA1 Entrez, Source | integrin, alpha 1 | 5518 | 0.021 | -0.3572 | No |
| 6 | RAP1A | RAP1A Entrez, Source | RAP1A, member of RAS oncogene family | 5896 | 0.016 | -0.3820 | No |
| 7 | GRB2 | GRB2 Entrez, Source | growth factor receptor-bound protein 2 | 6191 | 0.011 | -0.4015 | No |
| 8 | CRKL | CRKL Entrez, Source | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 7585 | -0.009 | -0.5041 | No |
| 9 | MAP2K2 | MAP2K2 Entrez, Source | mitogen-activated protein kinase kinase 2 | 8062 | -0.016 | -0.5364 | No |
| 10 | CSK | CSK Entrez, Source | c-src tyrosine kinase | 9286 | -0.038 | -0.6197 | No |
| 11 | MAPK1 | MAPK1 Entrez, Source | mitogen-activated protein kinase 1 | 9755 | -0.047 | -0.6443 | No |
| 12 | CAPNS1 | CAPNS1 Entrez, Source | calpain, small subunit 1 | 11209 | -0.086 | -0.7340 | Yes |
| 13 | ROCK1 | ROCK1 Entrez, Source | Rho-associated, coiled-coil containing protein kinase 1 | 11231 | -0.087 | -0.7160 | Yes |
| 14 | MAP2K1 | MAP2K1 Entrez, Source | mitogen-activated protein kinase kinase 1 | 11293 | -0.090 | -0.7003 | Yes |
| 15 | ITGB1 | ITGB1 Entrez, Source | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 11396 | -0.095 | -0.6866 | Yes |
| 16 | SRC | SRC Entrez, Source | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 11494 | -0.099 | -0.6715 | Yes |
| 17 | CAPN1 | CAPN1 Entrez, Source | calpain 1, (mu/I) large subunit | 11685 | -0.108 | -0.6614 | Yes |
| 18 | JUN | JUN Entrez, Source | jun oncogene | 11756 | -0.111 | -0.6415 | Yes |
| 19 | PTK2 | PTK2 Entrez, Source | PTK2 protein tyrosine kinase 2 | 11904 | -0.119 | -0.6258 | Yes |
| 20 | ACTN3 | ACTN3 Entrez, Source | actinin, alpha 3 | 11968 | -0.123 | -0.6028 | Yes |
| 21 | BCAR1 | BCAR1 Entrez, Source | breast cancer anti-estrogen resistance 1 | 12011 | -0.126 | -0.5775 | Yes |
| 22 | TLN1 | TLN1 Entrez, Source | talin 1 | 12039 | -0.127 | -0.5509 | Yes |
| 23 | MAPK3 | MAPK3 Entrez, Source | mitogen-activated protein kinase 3 | 12441 | -0.162 | -0.5444 | Yes |
| 24 | PXN | PXN Entrez, Source | paxillin | 12740 | -0.211 | -0.5191 | Yes |
| 25 | ZYX | ZYX Entrez, Source | zyxin | 12928 | -0.262 | -0.4742 | Yes |
| 26 | ACTN1 | ACTN1 Entrez, Source | actinin, alpha 1 | 13279 | -0.655 | -0.3528 | Yes |
| 27 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 13340 | -1.586 | 0.0002 | Yes |
