Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | IRITANI_ADPROX_DN |
| Enrichment Score (ES) | -0.6704434 |
| Normalized Enrichment Score (NES) | -1.9899164 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.006785091 |
| FWER p-Value | 0.186 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | NRCAM | NRCAM Entrez, Source | neuronal cell adhesion molecule | 696 | 0.174 | -0.0261 | No |
| 2 | BMP6 | BMP6 Entrez, Source | bone morphogenetic protein 6 | 1877 | 0.098 | -0.1000 | No |
| 3 | IGF2BP3 | IGF2BP3 Entrez, Source | insulin-like growth factor 2 mRNA binding protein 3 | 1965 | 0.095 | -0.0922 | No |
| 4 | LYL1 | LYL1 Entrez, Source | lymphoblastic leukemia derived sequence 1 | 1977 | 0.095 | -0.0788 | No |
| 5 | ARHGDIB | ARHGDIB Entrez, Source | Rho GDP dissociation inhibitor (GDI) beta | 2131 | 0.090 | -0.0766 | No |
| 6 | FAP | FAP Entrez, Source | fibroblast activation protein, alpha | 2539 | 0.078 | -0.0954 | No |
| 7 | MAPKAPK3 | MAPKAPK3 Entrez, Source | mitogen-activated protein kinase-activated protein kinase 3 | 2853 | 0.070 | -0.1083 | No |
| 8 | CDH2 | CDH2 Entrez, Source | cadherin 2, type 1, N-cadherin (neuronal) | 2940 | 0.068 | -0.1045 | No |
| 9 | CSPG2 | CSPG2 Entrez, Source | chondroitin sulfate proteoglycan 2 (versican) | 3728 | 0.051 | -0.1560 | No |
| 10 | SELP | SELP Entrez, Source | selectin P (granule membrane protein 140kDa, antigen CD62) | 3948 | 0.047 | -0.1653 | No |
| 11 | PDLIM4 | PDLIM4 Entrez, Source | PDZ and LIM domain 4 | 4357 | 0.040 | -0.1899 | No |
| 12 | CAP2 | CAP2 Entrez, Source | CAP, adenylate cyclase-associated protein, 2 (yeast) | 4920 | 0.030 | -0.2276 | No |
| 13 | LTBP2 | LTBP2 Entrez, Source | latent transforming growth factor beta binding protein 2 | 6275 | 0.010 | -0.3278 | No |
| 14 | PLAU | PLAU Entrez, Source | plasminogen activator, urokinase | 6332 | 0.009 | -0.3307 | No |
| 15 | IL6 | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 7239 | -0.004 | -0.3982 | No |
| 16 | SRPX | SRPX Entrez, Source | sushi-repeat-containing protein, X-linked | 7631 | -0.010 | -0.4262 | No |
| 17 | AXL | AXL Entrez, Source | AXL receptor tyrosine kinase | 8404 | -0.021 | -0.4810 | No |
| 18 | LPXN | LPXN Entrez, Source | leupaxin | 8598 | -0.025 | -0.4918 | No |
| 19 | ANXA6 | ANXA6 Entrez, Source | annexin A6 | 9062 | -0.033 | -0.5216 | No |
| 20 | ICAM2 | ICAM2 Entrez, Source | intercellular adhesion molecule 2 | 10161 | -0.056 | -0.5957 | No |
| 21 | RGS4 | RGS4 Entrez, Source | regulator of G-protein signalling 4 | 10391 | -0.061 | -0.6037 | No |
| 22 | TFEC | TFEC Entrez, Source | transcription factor EC | 10663 | -0.069 | -0.6137 | No |
| 23 | NRP1 | NRP1 Entrez, Source | neuropilin 1 | 11218 | -0.087 | -0.6423 | No |
| 24 | PRG1 | PRG1 Entrez, Source | proteoglycan 1, secretory granule | 11588 | -0.104 | -0.6544 | Yes |
| 25 | TCN2 | TCN2 Entrez, Source | transcobalamin II; macrocytic anemia | 11593 | -0.104 | -0.6390 | Yes |
| 26 | EMP3 | EMP3 Entrez, Source | epithelial membrane protein 3 | 12012 | -0.126 | -0.6514 | Yes |
| 27 | SLC38A6 | SLC38A6 Entrez, Source | solute carrier family 38, member 6 | 12082 | -0.130 | -0.6370 | Yes |
| 28 | MLLT11 | MLLT11 Entrez, Source | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 12260 | -0.145 | -0.6285 | Yes |
| 29 | PLA2G4A | PLA2G4A Entrez, Source | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 12414 | -0.160 | -0.6158 | Yes |
| 30 | CD59 | CD59 Entrez, Source | CD59 molecule, complement regulatory protein | 12491 | -0.169 | -0.5960 | Yes |
| 31 | ARL6IP5 | ARL6IP5 Entrez, Source | ADP-ribosylation-like factor 6 interacting protein 5 | 12549 | -0.178 | -0.5734 | Yes |
| 32 | MMP14 | MMP14 Entrez, Source | matrix metallopeptidase 14 (membrane-inserted) | 12629 | -0.189 | -0.5508 | Yes |
| 33 | PFKM | PFKM Entrez, Source | phosphofructokinase, muscle | 12804 | -0.226 | -0.5297 | Yes |
| 34 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 13011 | -0.297 | -0.5004 | Yes |
| 35 | LDHB | LDHB Entrez, Source | lactate dehydrogenase B | 13034 | -0.309 | -0.4553 | Yes |
| 36 | PRNP | PRNP Entrez, Source | prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia) | 13038 | -0.313 | -0.4083 | Yes |
| 37 | SERPINE1 | SERPINE1 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 13125 | -0.378 | -0.3578 | Yes |
| 38 | CD44 | CD44 Entrez, Source | CD44 molecule (Indian blood group) | 13174 | -0.431 | -0.2963 | Yes |
| 39 | PROCR | PROCR Entrez, Source | protein C receptor, endothelial (EPCR) | 13212 | -0.481 | -0.2264 | Yes |
| 40 | GBP2 | GBP2 Entrez, Source | guanylate binding protein 2, interferon-inducible | 13270 | -0.639 | -0.1342 | Yes |
| 41 | CCL2 | CCL2 Entrez, Source | chemokine (C-C motif) ligand 2 | 13317 | -0.925 | 0.0019 | Yes |
