Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | ISOMERASE_ACTIVITY |
| Enrichment Score (ES) | 0.69308907 |
| Normalized Enrichment Score (NES) | 1.9334993 |
| Nominal p-value | 0.002283105 |
| FDR q-value | 0.005747663 |
| FWER p-Value | 0.318 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | LSS | LSS Entrez, Source | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) | 91 | 0.425 | 0.1930 | Yes |
| 2 | IDI1 | IDI1 Entrez, Source | isopentenyl-diphosphate delta isomerase 1 | 136 | 0.372 | 0.3647 | Yes |
| 3 | EBP | EBP Entrez, Source | emopamil binding protein (sterol isomerase) | 221 | 0.298 | 0.4985 | Yes |
| 4 | GNE | GNE Entrez, Source | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase | 599 | 0.186 | 0.5577 | Yes |
| 5 | DDT | DDT Entrez, Source | D-dopachrome tautomerase | 1076 | 0.139 | 0.5870 | Yes |
| 6 | PDIA5 | PDIA5 Entrez, Source | protein disulfide isomerase family A, member 5 | 1141 | 0.134 | 0.6454 | Yes |
| 7 | PTGIS | PTGIS Entrez, Source | prostaglandin I2 (prostacyclin) synthase | 1288 | 0.125 | 0.6931 | Yes |
| 8 | PGM1 | PGM1 Entrez, Source | phosphoglucomutase 1 | 2063 | 0.092 | 0.6782 | No |
| 9 | P4HB | P4HB Entrez, Source | procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide | 3536 | 0.055 | 0.5936 | No |
| 10 | HSD3B1 | HSD3B1 Entrez, Source | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 | 4997 | 0.029 | 0.4977 | No |
| 11 | TXNDC4 | TXNDC4 Entrez, Source | thioredoxin domain containing 4 (endoplasmic reticulum) | 5084 | 0.028 | 0.5044 | No |
| 12 | TOP1 | TOP1 Entrez, Source | topoisomerase (DNA) I | 5107 | 0.028 | 0.5157 | No |
| 13 | PDIA6 | PDIA6 Entrez, Source | protein disulfide isomerase family A, member 6 | 5601 | 0.020 | 0.4882 | No |
| 14 | PPIE | PPIE Entrez, Source | peptidylprolyl isomerase E (cyclophilin E) | 5802 | 0.017 | 0.4813 | No |
| 15 | PTGDS | PTGDS Entrez, Source | prostaglandin D2 synthase 21kDa (brain) | 6738 | 0.003 | 0.4128 | No |
| 16 | BPGM | BPGM Entrez, Source | 2,3-bisphosphoglycerate mutase | 7060 | -0.001 | 0.3892 | No |
| 17 | PGAM2 | PGAM2 Entrez, Source | phosphoglycerate mutase 2 (muscle) | 7429 | -0.006 | 0.3645 | No |
| 18 | ERP29 | ERP29 Entrez, Source | endoplasmic reticulum protein 29 | 7864 | -0.013 | 0.3381 | No |
| 19 | TPI1 | TPI1 Entrez, Source | triosephosphate isomerase 1 | 8236 | -0.019 | 0.3191 | No |
| 20 | TOP2A | TOP2A Entrez, Source | topoisomerase (DNA) II alpha 170kDa | 9129 | -0.035 | 0.2684 | No |
| 21 | PDIA3 | PDIA3 Entrez, Source | protein disulfide isomerase family A, member 3 | 9691 | -0.045 | 0.2476 | No |
| 22 | PMM1 | PMM1 Entrez, Source | phosphomannomutase 1 | 10190 | -0.056 | 0.2366 | No |
