Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | LEE_ACOX1_DN |
| Enrichment Score (ES) | 0.5686434 |
| Normalized Enrichment Score (NES) | 1.8953527 |
| Nominal p-value | 0.0023474179 |
| FDR q-value | 0.007149156 |
| FWER p-Value | 0.483 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SLC27A5 | SLC27A5 Entrez, Source | solute carrier family 27 (fatty acid transporter), member 5 | 9 | 0.779 | 0.0790 | Yes |
| 2 | OTC | OTC Entrez, Source | ornithine carbamoyltransferase | 44 | 0.506 | 0.1281 | Yes |
| 3 | SLCO2B1 | SLCO2B1 Entrez, Source | solute carrier organic anion transporter family, member 2B1 | 61 | 0.481 | 0.1762 | Yes |
| 4 | PPP1R3C | PPP1R3C Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 3C | 71 | 0.452 | 0.2218 | Yes |
| 5 | KHK | KHK Entrez, Source | ketohexokinase (fructokinase) | 93 | 0.422 | 0.2633 | Yes |
| 6 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 110 | 0.403 | 0.3033 | Yes |
| 7 | HGD | HGD Entrez, Source | homogentisate 1,2-dioxygenase (homogentisate oxidase) | 126 | 0.385 | 0.3416 | Yes |
| 8 | G6PC | G6PC Entrez, Source | glucose-6-phosphatase, catalytic subunit | 129 | 0.383 | 0.3807 | Yes |
| 9 | C4BPA | C4BPA Entrez, Source | complement component 4 binding protein, alpha | 176 | 0.331 | 0.4110 | Yes |
| 10 | SLC37A4 | SLC37A4 Entrez, Source | solute carrier family 37 (glycerol-6-phosphate transporter), member 4 | 211 | 0.305 | 0.4397 | Yes |
| 11 | TDO2 | TDO2 Entrez, Source | tryptophan 2,3-dioxygenase | 358 | 0.245 | 0.4538 | Yes |
| 12 | HSD11B1 | HSD11B1 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 1 | 370 | 0.242 | 0.4777 | Yes |
| 13 | HAL | HAL Entrez, Source | histidine ammonia-lyase | 423 | 0.224 | 0.4967 | Yes |
| 14 | CYP26A1 | CYP26A1 Entrez, Source | cytochrome P450, family 26, subfamily A, polypeptide 1 | 562 | 0.191 | 0.5058 | Yes |
| 15 | NR1H3 | NR1H3 Entrez, Source | nuclear receptor subfamily 1, group H, member 3 | 583 | 0.188 | 0.5235 | Yes |
| 16 | BAAT | BAAT Entrez, Source | bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase) | 597 | 0.186 | 0.5416 | Yes |
| 17 | PAH | PAH Entrez, Source | phenylalanine hydroxylase | 628 | 0.182 | 0.5580 | Yes |
| 18 | OAT | OAT Entrez, Source | ornithine aminotransferase (gyrate atrophy) | 893 | 0.154 | 0.5539 | Yes |
| 19 | CYP4F2 | CYP4F2 Entrez, Source | cytochrome P450, family 4, subfamily F, polypeptide 2 | 933 | 0.150 | 0.5663 | Yes |
| 20 | MBL2 | MBL2 Entrez, Source | mannose-binding lectin (protein C) 2, soluble (opsonic defect) | 1090 | 0.138 | 0.5686 | Yes |
| 21 | GSTA3 | GSTA3 Entrez, Source | glutathione S-transferase A3 | 1488 | 0.114 | 0.5504 | No |
| 22 | PHLDA1 | PHLDA1 Entrez, Source | pleckstrin homology-like domain, family A, member 1 | 1708 | 0.105 | 0.5447 | No |
| 23 | PRODH | PRODH Entrez, Source | proline dehydrogenase (oxidase) 1 | 2331 | 0.084 | 0.5065 | No |
| 24 | DPP4 | DPP4 Entrez, Source | dipeptidyl-peptidase 4 (CD26, adenosine deaminase complexing protein 2) | 2611 | 0.076 | 0.4933 | No |
| 25 | SFTPD | SFTPD Entrez, Source | surfactant, pulmonary-associated protein D | 2883 | 0.069 | 0.4800 | No |
| 26 | CPOX | CPOX Entrez, Source | coproporphyrinogen oxidase | 2946 | 0.068 | 0.4823 | No |
| 27 | SERPINA1 | SERPINA1 Entrez, Source | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 3405 | 0.058 | 0.4538 | No |
| 28 | AKAP11 | AKAP11 Entrez, Source | A kinase (PRKA) anchor protein 11 | 3700 | 0.052 | 0.4369 | No |
| 29 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 4079 | 0.045 | 0.4131 | No |
| 30 | HPD | HPD Entrez, Source | 4-hydroxyphenylpyruvate dioxygenase | 4383 | 0.040 | 0.3944 | No |
| 31 | MYH1 | MYH1 Entrez, Source | myosin, heavy chain 1, skeletal muscle, adult | 5171 | 0.027 | 0.3379 | No |
| 32 | SLC29A1 | SLC29A1 Entrez, Source | solute carrier family 29 (nucleoside transporters), member 1 | 5361 | 0.024 | 0.3261 | No |
| 33 | TNNT3 | TNNT3 Entrez, Source | troponin T type 3 (skeletal, fast) | 6538 | 0.006 | 0.2383 | No |
| 34 | ATP2A1 | ATP2A1 Entrez, Source | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 | 8368 | -0.021 | 0.1029 | No |
| 35 | CYP7B1 | CYP7B1 Entrez, Source | cytochrome P450, family 7, subfamily B, polypeptide 1 | 9114 | -0.034 | 0.0504 | No |
| 36 | MASP1 | MASP1 Entrez, Source | mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) | 9195 | -0.035 | 0.0480 | No |
| 37 | GPR37 | GPR37 Entrez, Source | G protein-coupled receptor 37 (endothelin receptor type B-like) | 9392 | -0.040 | 0.0373 | No |
| 38 | HBP1 | HBP1 Entrez, Source | HMG-box transcription factor 1 | 9898 | -0.050 | 0.0044 | No |
| 39 | ELA2 | ELA2 Entrez, Source | elastase 2, neutrophil | 10427 | -0.062 | -0.0289 | No |
| 40 | RNASE4 | RNASE4 Entrez, Source | ribonuclease, RNase A family, 4 | 10748 | -0.071 | -0.0457 | No |
| 41 | SELENBP1 | SELENBP1 Entrez, Source | selenium binding protein 1 | 11162 | -0.084 | -0.0682 | No |
| 42 | NINJ1 | NINJ1 Entrez, Source | ninjurin 1 | 11476 | -0.099 | -0.0816 | No |
| 43 | IL1RAP | IL1RAP Entrez, Source | interleukin 1 receptor accessory protein | 11842 | -0.116 | -0.0972 | No |
| 44 | RGN | RGN Entrez, Source | regucalcin (senescence marker protein-30) | 12427 | -0.161 | -0.1246 | No |
| 45 | LIPC | LIPC Entrez, Source | lipase, hepatic | 13275 | -0.650 | -0.1219 | No |
| 46 | CA3 | CA3 Entrez, Source | carbonic anhydrase III, muscle specific | 13334 | -1.240 | 0.0006 | No |
