Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | LEE_CIP_DN |
| Enrichment Score (ES) | 0.548614 |
| Normalized Enrichment Score (NES) | 1.8263373 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.01231743 |
| FWER p-Value | 0.797 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | OTC | OTC Entrez, Source | ornithine carbamoyltransferase | 44 | 0.506 | 0.0586 | Yes |
| 2 | PPP1R3C | PPP1R3C Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 3C | 71 | 0.452 | 0.1121 | Yes |
| 3 | BHMT | BHMT Entrez, Source | betaine-homocysteine methyltransferase | 106 | 0.415 | 0.1603 | Yes |
| 4 | G6PC | G6PC Entrez, Source | glucose-6-phosphatase, catalytic subunit | 129 | 0.383 | 0.2056 | Yes |
| 5 | PON1 | PON1 Entrez, Source | paraoxonase 1 | 159 | 0.345 | 0.2457 | Yes |
| 6 | C4BPA | C4BPA Entrez, Source | complement component 4 binding protein, alpha | 176 | 0.331 | 0.2850 | Yes |
| 7 | ABAT | ABAT Entrez, Source | 4-aminobutyrate aminotransferase | 185 | 0.321 | 0.3238 | Yes |
| 8 | SLC37A4 | SLC37A4 Entrez, Source | solute carrier family 37 (glycerol-6-phosphate transporter), member 4 | 211 | 0.305 | 0.3592 | Yes |
| 9 | HSD11B1 | HSD11B1 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 1 | 370 | 0.242 | 0.3770 | Yes |
| 10 | HAL | HAL Entrez, Source | histidine ammonia-lyase | 423 | 0.224 | 0.4005 | Yes |
| 11 | CYP26A1 | CYP26A1 Entrez, Source | cytochrome P450, family 26, subfamily A, polypeptide 1 | 562 | 0.191 | 0.4135 | Yes |
| 12 | NR1H3 | NR1H3 Entrez, Source | nuclear receptor subfamily 1, group H, member 3 | 583 | 0.188 | 0.4350 | Yes |
| 13 | BAAT | BAAT Entrez, Source | bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase) | 597 | 0.186 | 0.4568 | Yes |
| 14 | PAH | PAH Entrez, Source | phenylalanine hydroxylase | 628 | 0.182 | 0.4769 | Yes |
| 15 | KYNU | KYNU Entrez, Source | kynureninase (L-kynurenine hydrolase) | 695 | 0.174 | 0.4932 | Yes |
| 16 | OAT | OAT Entrez, Source | ornithine aminotransferase (gyrate atrophy) | 893 | 0.154 | 0.4972 | Yes |
| 17 | CA5A | CA5A Entrez, Source | carbonic anhydrase VA, mitochondrial | 1034 | 0.142 | 0.5041 | Yes |
| 18 | MBL2 | MBL2 Entrez, Source | mannose-binding lectin (protein C) 2, soluble (opsonic defect) | 1090 | 0.138 | 0.5168 | Yes |
| 19 | SULT1B1 | SULT1B1 Entrez, Source | sulfotransferase family, cytosolic, 1B, member 1 | 1102 | 0.137 | 0.5327 | Yes |
| 20 | SLC17A3 | SLC17A3 Entrez, Source | solute carrier family 17 (sodium phosphate), member 3 | 1279 | 0.125 | 0.5348 | Yes |
| 21 | CYP2E1 | CYP2E1 Entrez, Source | cytochrome P450, family 2, subfamily E, polypeptide 1 | 1369 | 0.121 | 0.5429 | Yes |
| 22 | ACADSB | ACADSB Entrez, Source | acyl-Coenzyme A dehydrogenase, short/branched chain | 1480 | 0.114 | 0.5486 | Yes |
| 23 | PNLIPRP1 | PNLIPRP1 Entrez, Source | pancreatic lipase-related protein 1 | 2104 | 0.091 | 0.5129 | No |
| 24 | PRODH | PRODH Entrez, Source | proline dehydrogenase (oxidase) 1 | 2331 | 0.084 | 0.5062 | No |
| 25 | SLC2A2 | SLC2A2 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 2 | 2459 | 0.081 | 0.5065 | No |
| 26 | DPP4 | DPP4 Entrez, Source | dipeptidyl-peptidase 4 (CD26, adenosine deaminase complexing protein 2) | 2611 | 0.076 | 0.5045 | No |
| 27 | CYP7A1 | CYP7A1 Entrez, Source | cytochrome P450, family 7, subfamily A, polypeptide 1 | 4020 | 0.046 | 0.4042 | No |
| 28 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 4079 | 0.045 | 0.4053 | No |
| 29 | HPD | HPD Entrez, Source | 4-hydroxyphenylpyruvate dioxygenase | 4383 | 0.040 | 0.3874 | No |
| 30 | CTRC | CTRC Entrez, Source | chymotrypsin C (caldecrin) | 4883 | 0.031 | 0.3537 | No |
| 31 | PCK1 | PCK1 Entrez, Source | phosphoenolpyruvate carboxykinase 1 (soluble) | 6026 | 0.014 | 0.2694 | No |
| 32 | SLC1A2 | SLC1A2 Entrez, Source | solute carrier family 1 (glial high affinity glutamate transporter), member 2 | 6115 | 0.013 | 0.2644 | No |
| 33 | TNNT3 | TNNT3 Entrez, Source | troponin T type 3 (skeletal, fast) | 6538 | 0.006 | 0.2333 | No |
| 34 | PNLIP | PNLIP Entrez, Source | pancreatic lipase | 6618 | 0.005 | 0.2280 | No |
| 35 | CMAH | CMAH Entrez, Source | cytidine monophosphate-N-acetylneuraminic acid hydroxylase (CMP-N-acetylneuraminate monooxygenase) | 7234 | -0.004 | 0.1822 | No |
| 36 | TNNI2 | TNNI2 Entrez, Source | troponin I type 2 (skeletal, fast) | 7460 | -0.007 | 0.1661 | No |
| 37 | CYP7B1 | CYP7B1 Entrez, Source | cytochrome P450, family 7, subfamily B, polypeptide 1 | 9114 | -0.034 | 0.0460 | No |
| 38 | GPR37 | GPR37 Entrez, Source | G protein-coupled receptor 37 (endothelin receptor type B-like) | 9392 | -0.040 | 0.0300 | No |
| 39 | HBP1 | HBP1 Entrez, Source | HMG-box transcription factor 1 | 9898 | -0.050 | -0.0019 | No |
| 40 | DMBT1 | DMBT1 Entrez, Source | deleted in malignant brain tumors 1 | 9974 | -0.052 | -0.0012 | No |
| 41 | ELA2 | ELA2 Entrez, Source | elastase 2, neutrophil | 10427 | -0.062 | -0.0276 | No |
| 42 | RNASE4 | RNASE4 Entrez, Source | ribonuclease, RNase A family, 4 | 10748 | -0.071 | -0.0430 | No |
| 43 | SELENBP1 | SELENBP1 Entrez, Source | selenium binding protein 1 | 11162 | -0.084 | -0.0637 | No |
| 44 | MAPKAPK2 | MAPKAPK2 Entrez, Source | mitogen-activated protein kinase-activated protein kinase 2 | 11727 | -0.110 | -0.0926 | No |
| 45 | GSTA4 | GSTA4 Entrez, Source | glutathione S-transferase A4 | 11757 | -0.112 | -0.0811 | No |
| 46 | IL1RAP | IL1RAP Entrez, Source | interleukin 1 receptor accessory protein | 11842 | -0.116 | -0.0732 | No |
| 47 | TRPV2 | TRPV2 Entrez, Source | transient receptor potential cation channel, subfamily V, member 2 | 11876 | -0.118 | -0.0613 | No |
| 48 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 12413 | -0.160 | -0.0821 | No |
| 49 | CA3 | CA3 Entrez, Source | carbonic anhydrase III, muscle specific | 13334 | -1.240 | 0.0006 | No |
