Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | LEE_E2F1_DN |
| Enrichment Score (ES) | 0.72152966 |
| Normalized Enrichment Score (NES) | 2.33477 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FABP1 | FABP1 Entrez, Source | fatty acid binding protein 1, liver | 2 | 1.112 | 0.1422 | Yes |
| 2 | OTC | OTC Entrez, Source | ornithine carbamoyltransferase | 44 | 0.506 | 0.2038 | Yes |
| 3 | BHMT | BHMT Entrez, Source | betaine-homocysteine methyltransferase | 106 | 0.415 | 0.2523 | Yes |
| 4 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 110 | 0.403 | 0.3036 | Yes |
| 5 | C4BPA | C4BPA Entrez, Source | complement component 4 binding protein, alpha | 176 | 0.331 | 0.3410 | Yes |
| 6 | AQP8 | AQP8 Entrez, Source | aquaporin 8 | 195 | 0.312 | 0.3795 | Yes |
| 7 | PXMP2 | PXMP2 Entrez, Source | peroxisomal membrane protein 2, 22kDa | 202 | 0.309 | 0.4186 | Yes |
| 8 | RARRES1 | RARRES1 Entrez, Source | retinoic acid receptor responder (tazarotene induced) 1 | 239 | 0.290 | 0.4530 | Yes |
| 9 | GHR | GHR Entrez, Source | growth hormone receptor | 250 | 0.287 | 0.4890 | Yes |
| 10 | PPCS | PPCS Entrez, Source | phosphopantothenoylcysteine synthetase | 298 | 0.267 | 0.5196 | Yes |
| 11 | TDO2 | TDO2 Entrez, Source | tryptophan 2,3-dioxygenase | 358 | 0.245 | 0.5466 | Yes |
| 12 | HSD11B1 | HSD11B1 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 1 | 370 | 0.242 | 0.5767 | Yes |
| 13 | HAL | HAL Entrez, Source | histidine ammonia-lyase | 423 | 0.224 | 0.6014 | Yes |
| 14 | NR1H3 | NR1H3 Entrez, Source | nuclear receptor subfamily 1, group H, member 3 | 583 | 0.188 | 0.6135 | Yes |
| 15 | BAAT | BAAT Entrez, Source | bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase) | 597 | 0.186 | 0.6364 | Yes |
| 16 | ACSL1 | ACSL1 Entrez, Source | acyl-CoA synthetase long-chain family member 1 | 609 | 0.185 | 0.6592 | Yes |
| 17 | KYNU | KYNU Entrez, Source | kynureninase (L-kynurenine hydrolase) | 695 | 0.174 | 0.6750 | Yes |
| 18 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 800 | 0.163 | 0.6880 | Yes |
| 19 | OAT | OAT Entrez, Source | ornithine aminotransferase (gyrate atrophy) | 893 | 0.154 | 0.7008 | Yes |
| 20 | HADH2 | HADH2 Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase, type II | 1095 | 0.137 | 0.7033 | Yes |
| 21 | MDH1 | MDH1 Entrez, Source | malate dehydrogenase 1, NAD (soluble) | 1246 | 0.127 | 0.7082 | Yes |
| 22 | CYP2E1 | CYP2E1 Entrez, Source | cytochrome P450, family 2, subfamily E, polypeptide 1 | 1369 | 0.121 | 0.7145 | Yes |
| 23 | IGF1 | IGF1 Entrez, Source | insulin-like growth factor 1 (somatomedin C) | 1471 | 0.115 | 0.7215 | Yes |
| 24 | PNLIPRP1 | PNLIPRP1 Entrez, Source | pancreatic lipase-related protein 1 | 2104 | 0.091 | 0.6856 | No |
| 25 | ITPR1 | ITPR1 Entrez, Source | inositol 1,4,5-triphosphate receptor, type 1 | 2186 | 0.089 | 0.6908 | No |
| 26 | ALDH1A1 | ALDH1A1 Entrez, Source | aldehyde dehydrogenase 1 family, member A1 | 2239 | 0.087 | 0.6980 | No |
| 27 | SERPINF1 | SERPINF1 Entrez, Source | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 2345 | 0.084 | 0.7009 | No |
| 28 | DBI | DBI Entrez, Source | diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein) | 2576 | 0.077 | 0.6935 | No |
| 29 | ADIPOR2 | ADIPOR2 Entrez, Source | adiponectin receptor 2 | 2598 | 0.076 | 0.7017 | No |
| 30 | AKAP11 | AKAP11 Entrez, Source | A kinase (PRKA) anchor protein 11 | 3700 | 0.052 | 0.6255 | No |
| 31 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 4079 | 0.045 | 0.6028 | No |
| 32 | HPD | HPD Entrez, Source | 4-hydroxyphenylpyruvate dioxygenase | 4383 | 0.040 | 0.5851 | No |
| 33 | CFH | CFH Entrez, Source | complement factor H | 4536 | 0.037 | 0.5785 | No |
| 34 | CTRC | CTRC Entrez, Source | chymotrypsin C (caldecrin) | 4883 | 0.031 | 0.5564 | No |
| 35 | ELOVL5 | ELOVL5 Entrez, Source | ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast) | 4996 | 0.029 | 0.5517 | No |
| 36 | GSTO1 | GSTO1 Entrez, Source | glutathione S-transferase omega 1 | 5429 | 0.023 | 0.5221 | No |
| 37 | PCK1 | PCK1 Entrez, Source | phosphoenolpyruvate carboxykinase 1 (soluble) | 6026 | 0.014 | 0.4791 | No |
| 38 | PNLIP | PNLIP Entrez, Source | pancreatic lipase | 6618 | 0.005 | 0.4353 | No |
| 39 | ABCG2 | ABCG2 Entrez, Source | ATP-binding cassette, sub-family G (WHITE), member 2 | 8071 | -0.016 | 0.3281 | No |
| 40 | GPR37 | GPR37 Entrez, Source | G protein-coupled receptor 37 (endothelin receptor type B-like) | 9392 | -0.040 | 0.2339 | No |
| 41 | ZG16 | ZG16 Entrez, Source | - | 9423 | -0.040 | 0.2368 | No |
| 42 | ELA2 | ELA2 Entrez, Source | elastase 2, neutrophil | 10427 | -0.062 | 0.1693 | No |
| 43 | MAPKAPK2 | MAPKAPK2 Entrez, Source | mitogen-activated protein kinase-activated protein kinase 2 | 11727 | -0.110 | 0.0858 | No |
| 44 | IL1RAP | IL1RAP Entrez, Source | interleukin 1 receptor accessory protein | 11842 | -0.116 | 0.0921 | No |
| 45 | RGN | RGN Entrez, Source | regucalcin (senescence marker protein-30) | 12427 | -0.161 | 0.0688 | No |
