Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | LEE_MYC_DN |
| Enrichment Score (ES) | 0.77953357 |
| Normalized Enrichment Score (NES) | 2.533038 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | OTC | OTC Entrez, Source | ornithine carbamoyltransferase | 44 | 0.506 | 0.0667 | Yes |
| 2 | G0S2 | G0S2 Entrez, Source | G0/G1switch 2 | 66 | 0.461 | 0.1290 | Yes |
| 3 | BHMT | BHMT Entrez, Source | betaine-homocysteine methyltransferase | 106 | 0.415 | 0.1834 | Yes |
| 4 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 110 | 0.403 | 0.2390 | Yes |
| 5 | G6PC | G6PC Entrez, Source | glucose-6-phosphatase, catalytic subunit | 129 | 0.383 | 0.2907 | Yes |
| 6 | C4BPA | C4BPA Entrez, Source | complement component 4 binding protein, alpha | 176 | 0.331 | 0.3331 | Yes |
| 7 | AQP8 | AQP8 Entrez, Source | aquaporin 8 | 195 | 0.312 | 0.3749 | Yes |
| 8 | SLC37A4 | SLC37A4 Entrez, Source | solute carrier family 37 (glycerol-6-phosphate transporter), member 4 | 211 | 0.305 | 0.4160 | Yes |
| 9 | PFKFB1 | PFKFB1 Entrez, Source | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 | 230 | 0.293 | 0.4552 | Yes |
| 10 | RARRES1 | RARRES1 Entrez, Source | retinoic acid receptor responder (tazarotene induced) 1 | 239 | 0.290 | 0.4947 | Yes |
| 11 | RGS16 | RGS16 Entrez, Source | regulator of G-protein signalling 16 | 258 | 0.285 | 0.5329 | Yes |
| 12 | KLF15 | KLF15 Entrez, Source | Kruppel-like factor 15 | 278 | 0.275 | 0.5695 | Yes |
| 13 | DPYD | DPYD Entrez, Source | dihydropyrimidine dehydrogenase | 303 | 0.265 | 0.6045 | Yes |
| 14 | TDO2 | TDO2 Entrez, Source | tryptophan 2,3-dioxygenase | 358 | 0.245 | 0.6344 | Yes |
| 15 | FKBP5 | FKBP5 Entrez, Source | FK506 binding protein 5 | 406 | 0.229 | 0.6625 | Yes |
| 16 | HAL | HAL Entrez, Source | histidine ammonia-lyase | 423 | 0.224 | 0.6924 | Yes |
| 17 | IGFBP2 | IGFBP2 Entrez, Source | insulin-like growth factor binding protein 2, 36kDa | 473 | 0.209 | 0.7176 | Yes |
| 18 | HRSP12 | HRSP12 Entrez, Source | heat-responsive protein 12 | 519 | 0.198 | 0.7417 | Yes |
| 19 | KYNU | KYNU Entrez, Source | kynureninase (L-kynurenine hydrolase) | 695 | 0.174 | 0.7526 | Yes |
| 20 | HERPUD1 | HERPUD1 Entrez, Source | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 852 | 0.158 | 0.7627 | Yes |
| 21 | HSPA5 | HSPA5 Entrez, Source | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 909 | 0.152 | 0.7795 | Yes |
| 22 | IGF1 | IGF1 Entrez, Source | insulin-like growth factor 1 (somatomedin C) | 1471 | 0.115 | 0.7532 | No |
| 23 | PNLIPRP1 | PNLIPRP1 Entrez, Source | pancreatic lipase-related protein 1 | 2104 | 0.091 | 0.7183 | No |
| 24 | EFEMP1 | EFEMP1 Entrez, Source | EGF-containing fibulin-like extracellular matrix protein 1 | 2189 | 0.088 | 0.7242 | No |
| 25 | FGG | FGG Entrez, Source | fibrinogen gamma chain | 2208 | 0.088 | 0.7350 | No |
| 26 | PCOLCE | PCOLCE Entrez, Source | procollagen C-endopeptidase enhancer | 3905 | 0.048 | 0.6142 | No |
| 27 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 4079 | 0.045 | 0.6074 | No |
| 28 | SFXN1 | SFXN1 Entrez, Source | sideroflexin 1 | 4446 | 0.039 | 0.5852 | No |
| 29 | CFH | CFH Entrez, Source | complement factor H | 4536 | 0.037 | 0.5837 | No |
| 30 | CTRC | CTRC Entrez, Source | chymotrypsin C (caldecrin) | 4883 | 0.031 | 0.5620 | No |
| 31 | ELOVL5 | ELOVL5 Entrez, Source | ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast) | 4996 | 0.029 | 0.5576 | No |
| 32 | MEOX2 | MEOX2 Entrez, Source | mesenchyme homeobox 2 | 5492 | 0.022 | 0.5234 | No |
| 33 | PCK1 | PCK1 Entrez, Source | phosphoenolpyruvate carboxykinase 1 (soluble) | 6026 | 0.014 | 0.4853 | No |
| 34 | IGF2 | IGF2 Entrez, Source | insulin-like growth factor 2 (somatomedin A) | 6610 | 0.005 | 0.4421 | No |
| 35 | PNLIP | PNLIP Entrez, Source | pancreatic lipase | 6618 | 0.005 | 0.4423 | No |
| 36 | IL1R1 | IL1R1 Entrez, Source | interleukin 1 receptor, type I | 8618 | -0.025 | 0.2955 | No |
| 37 | SATB1 | SATB1 Entrez, Source | special AT-rich sequence binding protein 1 (binds to nuclear matrix/scaffold-associating DNA's) | 9100 | -0.034 | 0.2640 | No |
| 38 | ZG16 | ZG16 Entrez, Source | - | 9423 | -0.040 | 0.2454 | No |
| 39 | HBP1 | HBP1 Entrez, Source | HMG-box transcription factor 1 | 9898 | -0.050 | 0.2167 | No |
| 40 | DMBT1 | DMBT1 Entrez, Source | deleted in malignant brain tumors 1 | 9974 | -0.052 | 0.2182 | No |
| 41 | ELA2 | ELA2 Entrez, Source | elastase 2, neutrophil | 10427 | -0.062 | 0.1928 | No |
| 42 | HSPH1 | HSPH1 Entrez, Source | heat shock 105kDa/110kDa protein 1 | 11009 | -0.079 | 0.1600 | No |
| 43 | MAPKAPK2 | MAPKAPK2 Entrez, Source | mitogen-activated protein kinase-activated protein kinase 2 | 11727 | -0.110 | 0.1214 | No |
