Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | LEE_MYC_E2F1_DN |
| Enrichment Score (ES) | 0.7606405 |
| Normalized Enrichment Score (NES) | 2.4509554 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FABP1 | FABP1 Entrez, Source | fatty acid binding protein 1, liver | 2 | 1.112 | 0.1212 | Yes |
| 2 | OTC | OTC Entrez, Source | ornithine carbamoyltransferase | 44 | 0.506 | 0.1734 | Yes |
| 3 | G0S2 | G0S2 Entrez, Source | G0/G1switch 2 | 66 | 0.461 | 0.2220 | Yes |
| 4 | BHMT | BHMT Entrez, Source | betaine-homocysteine methyltransferase | 106 | 0.415 | 0.2643 | Yes |
| 5 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 110 | 0.403 | 0.3081 | Yes |
| 6 | G6PC | G6PC Entrez, Source | glucose-6-phosphatase, catalytic subunit | 129 | 0.383 | 0.3485 | Yes |
| 7 | C4BPA | C4BPA Entrez, Source | complement component 4 binding protein, alpha | 176 | 0.331 | 0.3812 | Yes |
| 8 | PXMP2 | PXMP2 Entrez, Source | peroxisomal membrane protein 2, 22kDa | 202 | 0.309 | 0.4130 | Yes |
| 9 | RARRES1 | RARRES1 Entrez, Source | retinoic acid receptor responder (tazarotene induced) 1 | 239 | 0.290 | 0.4419 | Yes |
| 10 | GHR | GHR Entrez, Source | growth hormone receptor | 250 | 0.287 | 0.4725 | Yes |
| 11 | RGS16 | RGS16 Entrez, Source | regulator of G-protein signalling 16 | 258 | 0.285 | 0.5031 | Yes |
| 12 | EPHX2 | EPHX2 Entrez, Source | epoxide hydrolase 2, cytoplasmic | 282 | 0.274 | 0.5313 | Yes |
| 13 | MAT1A | MAT1A Entrez, Source | methionine adenosyltransferase I, alpha | 315 | 0.262 | 0.5574 | Yes |
| 14 | TDO2 | TDO2 Entrez, Source | tryptophan 2,3-dioxygenase | 358 | 0.245 | 0.5810 | Yes |
| 15 | HSD11B1 | HSD11B1 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 1 | 370 | 0.242 | 0.6066 | Yes |
| 16 | HAL | HAL Entrez, Source | histidine ammonia-lyase | 423 | 0.224 | 0.6271 | Yes |
| 17 | IGFBP2 | IGFBP2 Entrez, Source | insulin-like growth factor binding protein 2, 36kDa | 473 | 0.209 | 0.6463 | Yes |
| 18 | NR1H3 | NR1H3 Entrez, Source | nuclear receptor subfamily 1, group H, member 3 | 583 | 0.188 | 0.6586 | Yes |
| 19 | BAAT | BAAT Entrez, Source | bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase) | 597 | 0.186 | 0.6780 | Yes |
| 20 | ACSL1 | ACSL1 Entrez, Source | acyl-CoA synthetase long-chain family member 1 | 609 | 0.185 | 0.6973 | Yes |
| 21 | KYNU | KYNU Entrez, Source | kynureninase (L-kynurenine hydrolase) | 695 | 0.174 | 0.7099 | Yes |
| 22 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 800 | 0.163 | 0.7198 | Yes |
| 23 | ALAD | ALAD Entrez, Source | aminolevulinate, delta-, dehydratase | 826 | 0.160 | 0.7354 | Yes |
| 24 | OAT | OAT Entrez, Source | ornithine aminotransferase (gyrate atrophy) | 893 | 0.154 | 0.7472 | Yes |
| 25 | CYP4F2 | CYP4F2 Entrez, Source | cytochrome P450, family 4, subfamily F, polypeptide 2 | 933 | 0.150 | 0.7606 | Yes |
| 26 | CYP2E1 | CYP2E1 Entrez, Source | cytochrome P450, family 2, subfamily E, polypeptide 1 | 1369 | 0.121 | 0.7411 | No |
| 27 | IGF1 | IGF1 Entrez, Source | insulin-like growth factor 1 (somatomedin C) | 1471 | 0.115 | 0.7460 | No |
| 28 | PNLIPRP1 | PNLIPRP1 Entrez, Source | pancreatic lipase-related protein 1 | 2104 | 0.091 | 0.7084 | No |
| 29 | SLC25A22 | SLC25A22 Entrez, Source | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 | 2140 | 0.090 | 0.7155 | No |
| 30 | ADIPOR2 | ADIPOR2 Entrez, Source | adiponectin receptor 2 | 2598 | 0.076 | 0.6895 | No |
| 31 | SFTPD | SFTPD Entrez, Source | surfactant, pulmonary-associated protein D | 2883 | 0.069 | 0.6757 | No |
| 32 | CPOX | CPOX Entrez, Source | coproporphyrinogen oxidase | 2946 | 0.068 | 0.6785 | No |
| 33 | FABP2 | FABP2 Entrez, Source | fatty acid binding protein 2, intestinal | 2972 | 0.067 | 0.6839 | No |
| 34 | ABCD3 | ABCD3 Entrez, Source | ATP-binding cassette, sub-family D (ALD), member 3 | 3314 | 0.060 | 0.6648 | No |
| 35 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 4079 | 0.045 | 0.6122 | No |
| 36 | HPD | HPD Entrez, Source | 4-hydroxyphenylpyruvate dioxygenase | 4383 | 0.040 | 0.5937 | No |
| 37 | CTRC | CTRC Entrez, Source | chymotrypsin C (caldecrin) | 4883 | 0.031 | 0.5596 | No |
| 38 | ELOVL5 | ELOVL5 Entrez, Source | ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast) | 4996 | 0.029 | 0.5544 | No |
| 39 | PCK1 | PCK1 Entrez, Source | phosphoenolpyruvate carboxykinase 1 (soluble) | 6026 | 0.014 | 0.4785 | No |
| 40 | CYP7B1 | CYP7B1 Entrez, Source | cytochrome P450, family 7, subfamily B, polypeptide 1 | 9114 | -0.034 | 0.2501 | No |
| 41 | HBP1 | HBP1 Entrez, Source | HMG-box transcription factor 1 | 9898 | -0.050 | 0.1967 | No |
| 42 | ELA2 | ELA2 Entrez, Source | elastase 2, neutrophil | 10427 | -0.062 | 0.1637 | No |
| 43 | MAPKAPK2 | MAPKAPK2 Entrez, Source | mitogen-activated protein kinase-activated protein kinase 2 | 11727 | -0.110 | 0.0781 | No |
| 44 | IL1RAP | IL1RAP Entrez, Source | interleukin 1 receptor accessory protein | 11842 | -0.116 | 0.0822 | No |
| 45 | TRPV2 | TRPV2 Entrez, Source | transient receptor potential cation channel, subfamily V, member 2 | 11876 | -0.118 | 0.0926 | No |
| 46 | RGN | RGN Entrez, Source | regucalcin (senescence marker protein-30) | 12427 | -0.161 | 0.0688 | No |
