Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | LIGAND_DEPENDENT_NUCLEAR_RECEPTOR_ACTIVITY |
| Enrichment Score (ES) | 0.5928311 |
| Normalized Enrichment Score (NES) | 1.6597894 |
| Nominal p-value | 0.006437768 |
| FDR q-value | 0.049343377 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | NR1I3 | NR1I3 Entrez, Source | nuclear receptor subfamily 1, group I, member 3 | 73 | 0.449 | 0.2074 | Yes |
| 2 | RARB | RARB Entrez, Source | retinoic acid receptor, beta | 214 | 0.304 | 0.3411 | Yes |
| 3 | RXRG | RXRG Entrez, Source | retinoid X receptor, gamma | 499 | 0.203 | 0.4161 | Yes |
| 4 | RXRA | RXRA Entrez, Source | retinoid X receptor, alpha | 566 | 0.190 | 0.5013 | Yes |
| 5 | PPARD | PPARD Entrez, Source | peroxisome proliferative activated receptor, delta | 1387 | 0.119 | 0.4964 | Yes |
| 6 | VDR | VDR Entrez, Source | vitamin D (1,25- dihydroxyvitamin D3) receptor | 1535 | 0.111 | 0.5381 | Yes |
| 7 | PTGER3 | PTGER3 Entrez, Source | prostaglandin E receptor 3 (subtype EP3) | 2093 | 0.091 | 0.5394 | Yes |
| 8 | THRB | THRB Entrez, Source | thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian) | 2315 | 0.085 | 0.5630 | Yes |
| 9 | PGRMC2 | PGRMC2 Entrez, Source | progesterone receptor membrane component 2 | 2434 | 0.082 | 0.5928 | Yes |
| 10 | ESR2 | ESR2 Entrez, Source | estrogen receptor 2 (ER beta) | 4553 | 0.037 | 0.4514 | No |
| 11 | THRA | THRA Entrez, Source | thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian) | 4857 | 0.032 | 0.4436 | No |
| 12 | NR3C1 | NR3C1 Entrez, Source | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 5252 | 0.025 | 0.4261 | No |
| 13 | NR1D1 | NR1D1 Entrez, Source | nuclear receptor subfamily 1, group D, member 1 | 5562 | 0.021 | 0.4128 | No |
| 14 | NR3C2 | NR3C2 Entrez, Source | nuclear receptor subfamily 3, group C, member 2 | 6857 | 0.002 | 0.3166 | No |
| 15 | PGR | PGR Entrez, Source | progesterone receptor | 7642 | -0.010 | 0.2623 | No |
| 16 | NR4A3 | NR4A3 Entrez, Source | nuclear receptor subfamily 4, group A, member 3 | 7647 | -0.010 | 0.2666 | No |
| 17 | RARA | RARA Entrez, Source | retinoic acid receptor, alpha | 8106 | -0.016 | 0.2400 | No |
| 18 | RXRB | RXRB Entrez, Source | retinoid X receptor, beta | 9083 | -0.034 | 0.1828 | No |
| 19 | NR2F6 | NR2F6 Entrez, Source | nuclear receptor subfamily 2, group F, member 6 | 9842 | -0.049 | 0.1489 | No |
| 20 | BRD8 | BRD8 Entrez, Source | bromodomain containing 8 | 10521 | -0.065 | 0.1287 | No |
| 21 | AR | AR Entrez, Source | androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease) | 10940 | -0.077 | 0.1337 | No |
| 22 | AHR | AHR Entrez, Source | aryl hydrocarbon receptor | 11463 | -0.098 | 0.1411 | No |
