Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | MATRIX_METALLOPROTEINASES |
| Enrichment Score (ES) | -0.8163921 |
| Normalized Enrichment Score (NES) | -2.0237596 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0045098583 |
| FWER p-Value | 0.106 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MMP12 | MMP12 Entrez, Source | matrix metallopeptidase 12 (macrophage elastase) | 3186 | 0.063 | -0.2216 | No |
| 2 | ARAF | ARAF Entrez, Source | v-raf murine sarcoma 3611 viral oncogene homolog | 3591 | 0.054 | -0.2369 | No |
| 3 | MMP9 | MMP9 Entrez, Source | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 3861 | 0.049 | -0.2434 | No |
| 4 | MMP16 | MMP16 Entrez, Source | matrix metallopeptidase 16 (membrane-inserted) | 4004 | 0.046 | -0.2412 | No |
| 5 | MMP8 | MMP8 Entrez, Source | matrix metallopeptidase 8 (neutrophil collagenase) | 4947 | 0.030 | -0.3035 | No |
| 6 | TNF | TNF Entrez, Source | tumor necrosis factor (TNF superfamily, member 2) | 6739 | 0.003 | -0.4369 | No |
| 7 | MMP3 | MMP3 Entrez, Source | matrix metallopeptidase 3 (stromelysin 1, progelatinase) | 8953 | -0.031 | -0.5943 | No |
| 8 | BSG | BSG Entrez, Source | basigin (Ok blood group) | 9146 | -0.035 | -0.5990 | No |
| 9 | MMP10 | MMP10 Entrez, Source | matrix metallopeptidase 10 (stromelysin 2) | 11789 | -0.113 | -0.7657 | No |
| 10 | MMP7 | MMP7 Entrez, Source | matrix metallopeptidase 7 (matrilysin, uterine) | 12465 | -0.166 | -0.7702 | Yes |
| 11 | MMP2 | MMP2 Entrez, Source | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) | 12615 | -0.187 | -0.7292 | Yes |
| 12 | MMP14 | MMP14 Entrez, Source | matrix metallopeptidase 14 (membrane-inserted) | 12629 | -0.189 | -0.6773 | Yes |
| 13 | TIMP3 | TIMP3 Entrez, Source | TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory) | 12978 | -0.283 | -0.6244 | Yes |
| 14 | MMP24 | MMP24 Entrez, Source | matrix metallopeptidase 24 (membrane-inserted) | 13184 | -0.446 | -0.5152 | Yes |
| 15 | TIMP1 | TIMP1 Entrez, Source | TIMP metallopeptidase inhibitor 1 | 13193 | -0.458 | -0.3880 | Yes |
| 16 | MMP11 | MMP11 Entrez, Source | matrix metallopeptidase 11 (stromelysin 3) | 13271 | -0.644 | -0.2140 | Yes |
| 17 | TIMP2 | TIMP2 Entrez, Source | TIMP metallopeptidase inhibitor 2 | 13306 | -0.786 | 0.0027 | Yes |
