Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | MCALPAINPATHWAY |
| Enrichment Score (ES) | -0.7341552 |
| Normalized Enrichment Score (NES) | -1.8955699 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.02145035 |
| FWER p-Value | 0.603 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | EGF | EGF Entrez, Source | epidermal growth factor (beta-urogastrone) | 1748 | 0.103 | -0.1060 | No |
| 2 | PRKAR2A | PRKAR2A Entrez, Source | protein kinase, cAMP-dependent, regulatory, type II, alpha | 2568 | 0.078 | -0.1484 | No |
| 3 | MYL2 | MYL2 Entrez, Source | myosin, light chain 2, regulatory, cardiac, slow | 3684 | 0.052 | -0.2193 | No |
| 4 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 4079 | 0.045 | -0.2380 | No |
| 5 | HRAS | HRAS Entrez, Source | v-Ha-ras Harvey rat sarcoma viral oncogene homolog | 4923 | 0.030 | -0.2938 | No |
| 6 | ITGA1 | ITGA1 Entrez, Source | integrin, alpha 1 | 5518 | 0.021 | -0.3331 | No |
| 7 | CXCR3 | CXCR3 Entrez, Source | chemokine (C-X-C motif) receptor 3 | 7038 | -0.001 | -0.4469 | No |
| 8 | MAPK1 | MAPK1 Entrez, Source | mitogen-activated protein kinase 1 | 9755 | -0.047 | -0.6393 | No |
| 9 | PRKAR1A | PRKAR1A Entrez, Source | protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) | 10251 | -0.058 | -0.6623 | No |
| 10 | CAPNS1 | CAPNS1 Entrez, Source | calpain, small subunit 1 | 11209 | -0.086 | -0.7131 | Yes |
| 11 | ITGB1 | ITGB1 Entrez, Source | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 11396 | -0.095 | -0.7039 | Yes |
| 12 | CAPN1 | CAPN1 Entrez, Source | calpain 1, (mu/I) large subunit | 11685 | -0.108 | -0.6990 | Yes |
| 13 | PTK2 | PTK2 Entrez, Source | PTK2 protein tyrosine kinase 2 | 11904 | -0.119 | -0.6863 | Yes |
| 14 | CAPN2 | CAPN2 Entrez, Source | calpain 2, (m/II) large subunit | 11927 | -0.120 | -0.6586 | Yes |
| 15 | TLN1 | TLN1 Entrez, Source | talin 1 | 12039 | -0.127 | -0.6357 | Yes |
| 16 | MAPK3 | MAPK3 Entrez, Source | mitogen-activated protein kinase 3 | 12441 | -0.162 | -0.6261 | Yes |
| 17 | PXN | PXN Entrez, Source | paxillin | 12740 | -0.211 | -0.5967 | Yes |
| 18 | PRKAR1B | PRKAR1B Entrez, Source | protein kinase, cAMP-dependent, regulatory, type I, beta | 12903 | -0.254 | -0.5468 | Yes |
| 19 | PRKAR2B | PRKAR2B Entrez, Source | protein kinase, cAMP-dependent, regulatory, type II, beta | 13042 | -0.314 | -0.4802 | Yes |
| 20 | VIL2 | VIL2 Entrez, Source | villin 2 (ezrin) | 13200 | -0.467 | -0.3776 | Yes |
| 21 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 13340 | -1.586 | 0.0002 | Yes |
