Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_72h_versus_single_gel_72h.class.cls
#double_gel_72h_versus_single_gel_72h_repos
Phenotypeclass.cls#double_gel_72h_versus_single_gel_72h_repos
Upregulated in classdouble_gel_72h
GeneSetMITOCHONDRIA
Enrichment Score (ES)0.42322716
Normalized Enrichment Score (NES)1.7950127
Nominal p-value0.0
FDR q-value0.016406279
FWER p-Value0.893
Table: GSEA Results Summary



Fig 1: Enrichment plot: MITOCHONDRIA   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1EHHADHEHHADH
Entrez,  Source
enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase60.9080.0320Yes
2PKLRPKLR
Entrez,  Source
pyruvate kinase, liver and RBC310.5610.0502Yes
3GLYATGLYAT
Entrez,  Source
glycine-N-acyltransferase330.5540.0700Yes
4OTCOTC
Entrez,  Source
ornithine carbamoyltransferase440.5060.0873Yes
5BCL2A1BCL2A1
Entrez,  Source
BCL2-related protein A1670.4590.1021Yes
6HMGCS2HMGCS2
Entrez,  Source
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial)1170.3960.1125Yes
7ACAA2ACAA2
Entrez,  Source
acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase)1350.3740.1246Yes
8GCKGCK
Entrez,  Source
glucokinase (hexokinase 4, maturity onset diabetes of the young 2)1400.3680.1375Yes
9LCATLCAT
Entrez,  Source
lecithin-cholesterol acyltransferase1420.3650.1505Yes
10PCPC
Entrez,  Source
pyruvate carboxylase1550.3470.1620Yes
11ABATABAT
Entrez,  Source
4-aminobutyrate aminotransferase1850.3210.1713Yes
12CABC1CABC1
Entrez,  Source
chaperone, ABC1 activity of bc1 complex homolog (S. pombe)2170.3010.1796Yes
13SARDHSARDH
Entrez,  Source
sarcosine dehydrogenase2370.2910.1886Yes
14CATCAT
Entrez,  Source
catalase2900.2690.1942Yes
15CPS1CPS1
Entrez,  Source
carbamoyl-phosphate synthetase 1, mitochondrial2920.2680.2037Yes
16CLPXCLPX
Entrez,  Source
ClpX caseinolytic peptidase X homolog (E. coli)3740.2410.2062Yes
17SLC25A10SLC25A10
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 103780.2400.2145Yes
18TSTTST
Entrez,  Source
thiosulfate sulfurtransferase (rhodanese)3880.2350.2223Yes
19MTHFD1MTHFD1
Entrez,  Source
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase4050.2290.2292Yes
20PDK4PDK4
Entrez,  Source
pyruvate dehydrogenase kinase, isozyme 44120.2270.2369Yes
21ALAS1ALAS1
Entrez,  Source
aminolevulinate, delta-, synthase 14190.2240.2445Yes
22TIMM8ATIMM8A
Entrez,  Source
translocase of inner mitochondrial membrane 8 homolog A (yeast)4250.2230.2521Yes
23TIMM9TIMM9
Entrez,  Source
translocase of inner mitochondrial membrane 9 homolog (yeast)4630.2120.2569Yes
24ACADVLACADVL
Entrez,  Source
acyl-Coenzyme A dehydrogenase, very long chain4820.2070.2629Yes
25BCS1LBCS1L
Entrez,  Source
BCS1-like (yeast)5040.2010.2685Yes
26ACAT1ACAT1
Entrez,  Source
acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase)5600.1910.2711Yes
27ATP5G1ATP5G1
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9)5610.1910.2779Yes
28PDHBPDHB
Entrez,  Source
pyruvate dehydrogenase (lipoamide) beta5630.1900.2847Yes
29SLC25A15SLC25A15
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 155950.1860.2890Yes
30ETFDHETFDH
Entrez,  Source
electron-transferring-flavoprotein dehydrogenase6030.1860.2951Yes
31ECHS1ECHS1
Entrez,  Source
enoyl Coenzyme A hydratase, short chain, 1, mitochondrial6330.1820.2994Yes
32BCKDHBBCKDHB
Entrez,  Source
branched chain keto acid dehydrogenase E1, beta polypeptide (maple syrup urine disease)6510.1790.3045Yes
33BCKDHABCKDHA
Entrez,  Source
branched chain keto acid dehydrogenase E1, alpha polypeptide6620.1780.3101Yes
34POLR1BPOLR1B
Entrez,  Source
polymerase (RNA) I polypeptide B, 128kDa6720.1770.3157Yes
35PDK1PDK1
Entrez,  Source
pyruvate dehydrogenase kinase, isozyme 16730.1760.3220Yes
36TATTAT
Entrez,  Source
tyrosine aminotransferase6740.1760.3283Yes
37SOD2SOD2
Entrez,  Source
superoxide dismutase 2, mitochondrial6780.1760.3344Yes
38HMGCLHMGCL
Entrez,  Source
3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (hydroxymethylglutaricaciduria)7320.1690.3364Yes
39CRY1CRY1
Entrez,  Source
cryptochrome 1 (photolyase-like)7340.1690.3423Yes
40MRPL46MRPL46
Entrez,  Source
mitochondrial ribosomal protein L467430.1680.3477Yes
41ETFBETFB
Entrez,  Source
electron-transfer-flavoprotein, beta polypeptide7460.1680.3536Yes
42SLC25A20SLC25A20
Entrez,  Source
solute carrier family 25 (carnitine/acylcarnitine translocase), member 208420.1580.3520Yes
43BCKDKBCKDK
Entrez,  Source
branched chain ketoacid dehydrogenase kinase8680.1560.3557Yes
44NDUFV2NDUFV2
Entrez,  Source
NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa8890.1540.3596Yes
45OATOAT
Entrez,  Source
ornithine aminotransferase (gyrate atrophy)8930.1540.3649Yes
46MRPS15MRPS15
Entrez,  Source
mitochondrial ribosomal protein S159360.1500.3670Yes
47TFB1MTFB1M
Entrez,  Source
transcription factor B1, mitochondrial9470.1490.3716Yes
48FXC1FXC1
Entrez,  Source
fracture callus 1 homolog (rat)9480.1490.3769Yes
49TIMM10TIMM10
Entrez,  Source
translocase of inner mitochondrial membrane 10 homolog (yeast)10210.1430.3766Yes
50PORPOR
Entrez,  Source
P450 (cytochrome) oxidoreductase10300.1420.3810Yes
51CA5ACA5A
Entrez,  Source
carbonic anhydrase VA, mitochondrial10340.1420.3859Yes
52CPT1ACPT1A
Entrez,  Source
carnitine palmitoyltransferase 1A (liver)10460.1400.3901Yes
53AMACRAMACR
Entrez,  Source
alpha-methylacyl-CoA racemase11430.1340.3875Yes
54PECIPECI
Entrez,  Source
peroxisomal D3,D2-enoyl-CoA isomerase11510.1330.3918Yes
55AFG3L2AFG3L2
Entrez,  Source
AFG3 ATPase family gene 3-like 2 (yeast)12420.1270.3894Yes
56SHMT2SHMT2
Entrez,  Source
serine hydroxymethyltransferase 2 (mitochondrial)13470.1220.3858Yes
57ATP5OATP5O
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein)13600.1210.3893Yes
58CYP2E1CYP2E1
Entrez,  Source
cytochrome P450, family 2, subfamily E, polypeptide 113690.1210.3930Yes
59AMTAMT
Entrez,  Source
aminomethyltransferase13970.1190.3951Yes
60TXN2TXN2
Entrez,  Source
thioredoxin 214540.1160.3950Yes
61MIPEPMIPEP
Entrez,  Source
mitochondrial intermediate peptidase14550.1160.3991Yes
62ACADSBACADSB
Entrez,  Source
acyl-Coenzyme A dehydrogenase, short/branched chain14800.1140.4014Yes
63DECR1DECR1
Entrez,  Source
2,4-dienoyl CoA reductase 1, mitochondrial15880.1090.3971Yes
64TFB2MTFB2M
Entrez,  Source
transcription factor B2, mitochondrial16040.1090.3999Yes
65MBMB
Entrez,  Source
myoglobin16070.1090.4036Yes
66VAV1VAV1
Entrez,  Source
vav 1 oncogene16420.1070.4048Yes
67MRPL12MRPL12
Entrez,  Source
mitochondrial ribosomal protein L1216520.1070.4080Yes
68MAOBMAOB
Entrez,  Source
monoamine oxidase B17790.1020.4020Yes
69CYP11B1CYP11B1
Entrez,  Source
cytochrome P450, family 11, subfamily B, polypeptide 117890.1020.4049Yes
70MTIF2MTIF2
Entrez,  Source
mitochondrial translational initiation factor 217970.1010.4080Yes
71NDUFS1NDUFS1
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)18170.1010.4102Yes
72SURF1SURF1
Entrez,  Source
surfeit 118480.1000.4114Yes
73MRPS7MRPS7
Entrez,  Source
mitochondrial ribosomal protein S719300.0960.4087Yes
74SUPV3L1SUPV3L1
Entrez,  Source
suppressor of var1, 3-like 1 (S. cerevisiae)19310.0960.4121Yes
75IDH3AIDH3A
Entrez,  Source
isocitrate dehydrogenase 3 (NAD+) alpha19850.0940.4115Yes
76COQ7COQ7
Entrez,  Source
coenzyme Q7 homolog, ubiquinone (yeast)20160.0930.4125Yes
77CYP27A1CYP27A1
Entrez,  Source
cytochrome P450, family 27, subfamily A, polypeptide 120330.0930.4146Yes
78NFS1NFS1
Entrez,  Source
NFS1 nitrogen fixation 1 (S. cerevisiae)21000.0910.4128Yes
79MRPS18BMRPS18B
Entrez,  Source
mitochondrial ribosomal protein S18B21180.0900.4147Yes
80SLC25A22SLC25A22
Entrez,  Source
solute carrier family 25 (mitochondrial carrier: glutamate), member 2221400.0900.4164Yes
81COX7BCOX7B
Entrez,  Source
cytochrome c oxidase subunit VIIb21570.0890.4183Yes
82HADHAHADHA
Entrez,  Source
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit21740.0890.4203Yes
83TOMM70ATOMM70A
Entrez,  Source
translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)22680.0860.4163Yes
84ACP6ACP6
Entrez,  Source
acid phosphatase 6, lysophosphatidic22950.0850.4173Yes
85ATP5G2ATP5G2
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9)23180.0850.4187Yes
86MDH2MDH2
Entrez,  Source
malate dehydrogenase 2, NAD (mitochondrial)24090.0820.4147Yes
87ATP5C1ATP5C1
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 124370.0820.4156Yes
88AK2AK2
Entrez,  Source
adenylate kinase 224530.0810.4173Yes
89MRPL34MRPL34
Entrez,  Source
mitochondrial ribosomal protein L3424870.0800.4177Yes
90CPT1BCPT1B
Entrez,  Source
carnitine palmitoyltransferase 1B (muscle)24960.0800.4199Yes
91PRSS15PRSS15
Entrez,  Source
protease, serine, 1525070.0800.4220Yes
92SDHDSDHD
Entrez,  Source
succinate dehydrogenase complex, subunit D, integral membrane protein25290.0790.4232Yes
93ABCB8ABCB8
Entrez,  Source
ATP-binding cassette, sub-family B (MDR/TAP), member 826240.0760.4188No
94IDH3BIDH3B
Entrez,  Source
isocitrate dehydrogenase 3 (NAD+) beta26480.0750.4197No
95NDUFA8NDUFA8
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa27350.0730.4157No
96MRPL2MRPL2
Entrez,  Source
mitochondrial ribosomal protein L227380.0730.4182No
97SDHASDHA
Entrez,  Source
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)27800.0720.4176No
98PDCD8PDCD8
Entrez,  Source
programmed cell death 8 (apoptosis-inducing factor)28030.0710.4185No
99GNASGNAS
Entrez,  Source
GNAS complex locus28150.0710.4202No
100SLC25A1SLC25A1
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 129120.0690.4153No
101DAP3DAP3
Entrez,  Source
death associated protein 329660.0670.4136No
102ENDOGENDOG
Entrez,  Source
endonuclease G29810.0670.4150No
103HSPE1HSPE1
Entrez,  Source
heat shock 10kDa protein 1 (chaperonin 10)30200.0660.4144No
104ACO2ACO2
Entrez,  Source
aconitase 2, mitochondrial31360.0640.4079No
105DLDDLD
Entrez,  Source
dihydrolipoamide dehydrogenase31420.0630.4098No
106MRPL19MRPL19
Entrez,  Source
mitochondrial ribosomal protein L1931660.0630.4103No
107NDUFS2NDUFS2
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)31720.0630.4122No
108DNM1LDNM1L
Entrez,  Source
dynamin 1-like31840.0630.4136No
109UQCRC2UQCRC2
Entrez,  Source
ubiquinol-cytochrome c reductase core protein II31870.0630.4157No
110POLGPOLG
Entrez,  Source
polymerase (DNA directed), gamma32310.0620.4146No
111COX5BCOX5B
Entrez,  Source
cytochrome c oxidase subunit Vb32750.0610.4135No
112TIMM17ATIMM17A
Entrez,  Source
translocase of inner mitochondrial membrane 17 homolog A (yeast)32920.0600.4144No
113PCCBPCCB
Entrez,  Source
propionyl Coenzyme A carboxylase, beta polypeptide34170.0580.4070No
114SLC25A5SLC25A5
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 534180.0580.4090No
115MAOAMAOA
Entrez,  Source
monoamine oxidase A34270.0570.4105No
116MRPL11MRPL11
Entrez,  Source
mitochondrial ribosomal protein L1135290.0550.4047No
117TIMM8BTIMM8B
Entrez,  Source
translocase of inner mitochondrial membrane 8 homolog B (yeast)35590.0550.4045No
118ATP5EATP5E
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit36340.0530.4007No
119MRPL16MRPL16
Entrez,  Source
mitochondrial ribosomal protein L1636710.0530.3999No
120COX7A2COX7A2
Entrez,  Source
cytochrome c oxidase subunit VIIa polypeptide 2 (liver)36810.0520.4010No
121ATP5F1ATP5F1
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B138420.0490.3906No
122MPSTMPST
Entrez,  Source
mercaptopyruvate sulfurtransferase38830.0490.3893No
123UQCRC1UQCRC1
Entrez,  Source
ubiquinol-cytochrome c reductase core protein I39030.0480.3895No
124DBTDBT
Entrez,  Source
dihydrolipoamide branched chain transacylase E239120.0480.3906No
125RAF1RAF1
Entrez,  Source
v-raf-1 murine leukemia viral oncogene homolog 139410.0480.3902No
126TFAMTFAM
Entrez,  Source
transcription factor A, mitochondrial39720.0470.3896No
127SPG7SPG7
Entrez,  Source
spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive)39910.0470.3899No
128CYP7A1CYP7A1
Entrez,  Source
cytochrome P450, family 7, subfamily A, polypeptide 140200.0460.3894No
129UQCRFS1UQCRFS1
Entrez,  Source
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 140730.0450.3870No
130DCIDCI
Entrez,  Source
dodecenoyl-Coenzyme A delta isomerase (3,2 trans-enoyl-Coenzyme A isomerase)41670.0430.3815No
131SLC25A11SLC25A11
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 1141710.0430.3828No
132CSCS
Entrez,  Source
citrate synthase41750.0430.3841No
133ATP5BATP5B
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide41930.0430.3844No
134ATP5JATP5J
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F641940.0430.3859No
135STARSTAR
Entrez,  Source
steroidogenic acute regulator42090.0430.3863No
136CYP27B1CYP27B1
Entrez,  Source
cytochrome P450, family 27, subfamily B, polypeptide 142180.0430.3873No
137ATP5G3ATP5G3
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)42220.0430.3885No
138ATP5IATP5I
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit E42690.0420.3865No
139PRDX3PRDX3
Entrez,  Source
peroxiredoxin 342710.0420.3879No
140ACADMACADM
Entrez,  Source
acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain42990.0410.3874No
141COX6A1COX6A1
Entrez,  Source
cytochrome c oxidase subunit VIa polypeptide 143670.0400.3837No
142SNCASNCA
Entrez,  Source
synuclein, alpha (non A4 component of amyloid precursor)43780.0400.3843No
143SSBP1SSBP1
Entrez,  Source
single-stranded DNA binding protein 144110.0390.3833No
144COX5ACOX5A
Entrez,  Source
cytochrome c oxidase subunit Va44420.0390.3824No
145ATP5HATP5H
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d44810.0380.3808No
146NDUFC2NDUFC2
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa45790.0360.3747No
147HADHBHADHB
Entrez,  Source
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit46750.0350.3687No
148NDUFS4NDUFS4
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)47530.0330.3640No
149IVDIVD
Entrez,  Source
isovaleryl Coenzyme A dehydrogenase47830.0330.3630No
150NDUFS6NDUFS6
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)48990.0310.3553No
151MRPL41MRPL41
Entrez,  Source
mitochondrial ribosomal protein L4149210.0300.3548No
152MRPL44MRPL44
Entrez,  Source
mitochondrial ribosomal protein L4450270.0290.3478No
153COX6CCOX6C
Entrez,  Source
cytochrome c oxidase subunit VIc50360.0290.3482No
154TXNRD2TXNRD2
Entrez,  Source
thioredoxin reductase 250550.0280.3478No
155GLUD1GLUD1
Entrez,  Source
glutamate dehydrogenase 150870.0280.3464No
156TIMM13TIMM13
Entrez,  Source
translocase of inner mitochondrial membrane 13 homolog (yeast)51460.0270.3430No
157C1QBPC1QBP
Entrez,  Source
complement component 1, q subcomponent binding protein51570.0270.3432No
158CLN3CLN3
Entrez,  Source
ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)52080.0260.3403No
159TOMM40TOMM40
Entrez,  Source
translocase of outer mitochondrial membrane 40 homolog (yeast)52280.0260.3398No
160UQCRBUQCRB
Entrez,  Source
ubiquinol-cytochrome c reductase binding protein52310.0260.3405No
161COX4I1COX4I1
Entrez,  Source
cytochrome c oxidase subunit IV isoform 152450.0250.3404No
162NR3C1NR3C1
Entrez,  Source
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)52520.0250.3409No
163CYBBCYBB
Entrez,  Source
cytochrome b-245, beta polypeptide (chronic granulomatous disease)53120.0240.3373No
164ATP5DATP5D
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit53230.0240.3374No
165ETFAETFA
Entrez,  Source
electron-transfer-flavoprotein, alpha polypeptide (glutaric aciduria II)53360.0240.3373No
166CA5BCA5B
Entrez,  Source
carbonic anhydrase VB, mitochondrial53380.0240.3381No
167GPX4GPX4
Entrez,  Source
glutathione peroxidase 4 (phospholipid hydroperoxidase)53730.0240.3363No
168ATP5SATP5S
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit s (factor B)54140.0230.3341No
169MRPL24MRPL24
Entrez,  Source
mitochondrial ribosomal protein L2454440.0230.3327No
170MRPL17MRPL17
Entrez,  Source
mitochondrial ribosomal protein L1754580.0220.3325No
171AK3AK3
Entrez,  Source
adenylate kinase 355400.0210.3271No
172IMMTIMMT
Entrez,  Source
inner membrane protein, mitochondrial (mitofilin)56520.0200.3193No
173NDUFB4NDUFB4
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa56560.0190.3197No
174SLC25A21SLC25A21
Entrez,  Source
solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 2156790.0190.3187No
175SUCLG1SUCLG1
Entrez,  Source
succinate-CoA ligase, GDP-forming, alpha subunit57380.0180.3150No
176SDHCSDHC
Entrez,  Source
succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa57890.0180.3118No
177PDHA1PDHA1
Entrez,  Source
pyruvate dehydrogenase (lipoamide) alpha 157970.0170.3119No
178ACADLACADL
Entrez,  Source
acyl-Coenzyme A dehydrogenase, long chain58120.0170.3114No
179ACADSACADS
Entrez,  Source
acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain58860.0160.3064No
180GOT2GOT2
Entrez,  Source
glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)59160.0150.3047No
181DHODHDHODH
Entrez,  Source
dihydroorotate dehydrogenase59330.0150.3041No
182MRPL9MRPL9
Entrez,  Source
mitochondrial ribosomal protein L959570.0150.3028No
183VDAC2VDAC2
Entrez,  Source
voltage-dependent anion channel 259870.0140.3011No
184TOMM22TOMM22
Entrez,  Source
translocase of outer mitochondrial membrane 22 homolog (yeast)60980.0130.2932No
185SLC1A2SLC1A2
Entrez,  Source
solute carrier family 1 (glial high affinity glutamate transporter), member 261150.0130.2924No
186BIDBID
Entrez,  Source
BH3 interacting domain death agonist61250.0120.2922No
187TP53TP53
Entrez,  Source
tumor protein p53 (Li-Fraumeni syndrome)61580.0120.2901No
188ALDH2ALDH2
Entrez,  Source
aldehyde dehydrogenase 2 family (mitochondrial)61750.0120.2893No
189MTX2MTX2
Entrez,  Source
metaxin 262060.0110.2874No
190GPD2GPD2
Entrez,  Source
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)62370.0110.2855No
191HSPD1HSPD1
Entrez,  Source
heat shock 60kDa protein 1 (chaperonin)62420.0110.2856No
192MRPL13MRPL13
Entrez,  Source
mitochondrial ribosomal protein L1363630.0080.2767No
193FDXRFDXR
Entrez,  Source
ferredoxin reductase63910.0080.2750No
194UCP1UCP1
Entrez,  Source
uncoupling protein 1 (mitochondrial, proton carrier)64210.0070.2730No
195NME2NME2
Entrez,  Source
non-metastatic cells 2, protein (NM23B) expressed in64990.0060.2674No
196ARG2ARG2
Entrez,  Source
arginase, type II65800.0060.2614No
197CYCSCYCS
Entrez,  Source
cytochrome c, somatic67070.0040.2519No
198TOMM20TOMM20
Entrez,  Source
translocase of outer mitochondrial membrane 20 homolog (yeast)7046-0.0010.2261No
199MTERFMTERF
Entrez,  Source
mitochondrial transcription termination factor7209-0.0030.2139No
200NDUFA5NDUFA5
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa7283-0.0040.2085No
201UQCRHUQCRH
Entrez,  Source
ubiquinol-cytochrome c reductase hinge protein7358-0.0050.2030No
202PMPCBPMPCB
Entrez,  Source
peptidase (mitochondrial processing) beta7633-0.0100.1824No
203YME1L1YME1L1
Entrez,  Source
YME1-like 1 (S. cerevisiae)7967-0.0140.1575No
204YWHAEYWHAE
Entrez,  Source
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide8149-0.0170.1442No
205TIMM44TIMM44
Entrez,  Source
translocase of inner mitochondrial membrane 44 homolog (yeast)8155-0.0170.1445No
206UCP3UCP3
Entrez,  Source
uncoupling protein 3 (mitochondrial, proton carrier)8164-0.0170.1445No
207TIMM22TIMM22
Entrez,  Source
translocase of inner mitochondrial membrane 22 homolog (yeast)8179-0.0180.1440No
208ATPIF1ATPIF1
Entrez,  Source
ATPase inhibitory factor 18423-0.0220.1262No
209DIABLODIABLO
Entrez,  Source
diablo homolog (Drosophila)8809-0.0280.0978No
210PLA2G1BPLA2G1B
Entrez,  Source
phospholipase A2, group IB (pancreas)8831-0.0290.0973No
211SLC1A3SLC1A3
Entrez,  Source
solute carrier family 1 (glial high affinity glutamate transporter), member 38857-0.0290.0964No
212BCL2BCL2
Entrez,  Source
B-cell CLL/lymphoma 28887-0.0300.0952No
213MFN2MFN2
Entrez,  Source
mitofusin 29004-0.0320.0875No
214RANRAN
Entrez,  Source
RAN, member RAS oncogene family9203-0.0360.0737No
215SLC1A1SLC1A1
Entrez,  Source
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 19452-0.0410.0562No
216LYPLA2LYPLA2
Entrez,  Source
lysophospholipase II9600-0.0430.0465No
217VDAC3VDAC3
Entrez,  Source
voltage-dependent anion channel 39603-0.0430.0479No
218MRPS18AMRPS18A
Entrez,  Source
mitochondrial ribosomal protein S18A9675-0.0450.0441No
219BAXBAX
Entrez,  Source
BCL2-associated X protein9773-0.0470.0384No
220BCAT2BCAT2
Entrez,  Source
branched chain aminotransferase 2, mitochondrial9815-0.0480.0369No
221MRPL49MRPL49
Entrez,  Source
mitochondrial ribosomal protein L499821-0.0480.0383No
222CYP11A1CYP11A1
Entrez,  Source
cytochrome P450, family 11, subfamily A, polypeptide 110102-0.0540.0188No
223COX15COX15
Entrez,  Source
COX15 homolog, cytochrome c oxidase assembly protein (yeast)10424-0.062-0.0035No
224BCL2L1BCL2L1
Entrez,  Source
BCL2-like 110828-0.073-0.0317No
225CDC42BPBCDC42BPB
Entrez,  Source
CDC42 binding protein kinase beta (DMPK-like)10847-0.074-0.0304No
226DUTDUT
Entrez,  Source
dUTP pyrophosphatase10990-0.078-0.0384No
227DLATDLAT
Entrez,  Source
dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)10995-0.078-0.0359No
228CYP20A1CYP20A1
Entrez,  Source
cytochrome P450, family 20, subfamily A, polypeptide 111047-0.080-0.0370No
229SLC25A3SLC25A3
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 311129-0.083-0.0402No
230ANXA7ANXA7
Entrez,  Source
annexin A711132-0.083-0.0374No
231BNIP3LBNIP3L
Entrez,  Source
BCL2/adenovirus E1B 19kDa interacting protein 3-like11360-0.093-0.0514No
232FDX1FDX1
Entrez,  Source
ferredoxin 111489-0.099-0.0576No
233TPOTPO
Entrez,  Source
thyroid peroxidase11532-0.101-0.0572No
234GATMGATM
Entrez,  Source
glycine amidinotransferase (L-arginine:glycine amidinotransferase)11580-0.103-0.0571No
235CROTCROT
Entrez,  Source
carnitine O-octanoyltransferase11691-0.109-0.0617No
236FIBPFIBP
Entrez,  Source
fibroblast growth factor (acidic) intracellular binding protein11877-0.118-0.0716No
237PLA2G2APLA2G2A
Entrez,  Source
phospholipase A2, group IIA (platelets, synovial fluid)11878-0.118-0.0674No
238MTCH1MTCH1
Entrez,  Source
mitochondrial carrier homolog 1 (C. elegans)12038-0.127-0.0750No
239HK1HK1
Entrez,  Source
hexokinase 112060-0.129-0.0720No
240BAK1BAK1
Entrez,  Source
BCL2-antagonist/killer 112070-0.129-0.0680No
241APPAPP
Entrez,  Source
amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease)12119-0.132-0.0669No
242DNASE2DNASE2
Entrez,  Source
deoxyribonuclease II, lysosomal12199-0.139-0.0680No
243ERBB2ERBB2
Entrez,  Source
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)12233-0.142-0.0654No
244PRKCDPRKCD
Entrez,  Source
protein kinase C, delta12254-0.144-0.0618No
245CASP8CASP8
Entrez,  Source
caspase 8, apoptosis-related cysteine peptidase12395-0.157-0.0669No
246UCP2UCP2
Entrez,  Source
uncoupling protein 2 (mitochondrial, proton carrier)12505-0.172-0.0691No
247SLC25A4SLC25A4
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 412710-0.207-0.0773No
248MAP3K1MAP3K1
Entrez,  Source
mitogen-activated protein kinase kinase kinase 112714-0.208-0.0700No
249PYGBPYGB
Entrez,  Source
phosphorylase, glycogen; brain12718-0.208-0.0628No
250BIKBIK
Entrez,  Source
BCL2-interacting killer (apoptosis-inducing)12782-0.219-0.0598No
251CYBACYBA
Entrez,  Source
cytochrome b-245, alpha polypeptide12921-0.260-0.0611No
252CRATCRAT
Entrez,  Source
carnitine acetyltransferase13012-0.297-0.0573No
253COX6A2COX6A2
Entrez,  Source
cytochrome c oxidase subunit VIa polypeptide 213057-0.324-0.0491No
254LGALS3LGALS3
Entrez,  Source
lectin, galactoside-binding, soluble, 3 (galectin 3)13064-0.327-0.0378No
255CASP2CASP2
Entrez,  Source
caspase 2, apoptosis-related cysteine peptidase (neural precursor cell expressed, developmentally down-regulated 2)13127-0.379-0.0290No
256APAF1APAF1
Entrez,  Source
apoptotic peptidase activating factor13156-0.411-0.0165No
257POPDC2POPDC2
Entrez,  Source
popeye domain containing 213157-0.411-0.0018No
258NGFRAP1NGFRAP1
Entrez,  Source
nerve growth factor receptor (TNFRSF16) associated protein 113183-0.4430.0122No
Table: GSEA details [plain text format]



Fig 2: MITOCHONDRIA   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: MITOCHONDRIA: Random ES distribution   
Gene set null distribution of ES for MITOCHONDRIA