Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | MITOCHONDRIAL_MATRIX |
| Enrichment Score (ES) | 0.6213862 |
| Normalized Enrichment Score (NES) | 1.7151015 |
| Nominal p-value | 0.0065645515 |
| FDR q-value | 0.033116244 |
| FWER p-Value | 0.997 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | BCKDHB | BCKDHB Entrez, Source | branched chain keto acid dehydrogenase E1, beta polypeptide (maple syrup urine disease) | 651 | 0.179 | 0.0418 | Yes |
| 2 | BCKDHA | BCKDHA Entrez, Source | branched chain keto acid dehydrogenase E1, alpha polypeptide | 662 | 0.178 | 0.1312 | Yes |
| 3 | ETFB | ETFB Entrez, Source | electron-transfer-flavoprotein, beta polypeptide | 746 | 0.168 | 0.2098 | Yes |
| 4 | MRPL40 | MRPL40 Entrez, Source | mitochondrial ribosomal protein L40 | 854 | 0.157 | 0.2814 | Yes |
| 5 | BCKDK | BCKDK Entrez, Source | branched chain ketoacid dehydrogenase kinase | 868 | 0.156 | 0.3594 | Yes |
| 6 | MRPS15 | MRPS15 Entrez, Source | mitochondrial ribosomal protein S15 | 936 | 0.150 | 0.4302 | Yes |
| 7 | DNAJA3 | DNAJA3 Entrez, Source | DnaJ (Hsp40) homolog, subfamily A, member 3 | 972 | 0.147 | 0.5021 | Yes |
| 8 | TFB2M | TFB2M Entrez, Source | transcription factor B2, mitochondrial | 1604 | 0.109 | 0.5098 | Yes |
| 9 | MRPL12 | MRPL12 Entrez, Source | mitochondrial ribosomal protein L12 | 1652 | 0.107 | 0.5602 | Yes |
| 10 | SUPV3L1 | SUPV3L1 Entrez, Source | suppressor of var1, 3-like 1 (S. cerevisiae) | 1931 | 0.096 | 0.5880 | Yes |
| 11 | NFS1 | NFS1 Entrez, Source | NFS1 nitrogen fixation 1 (S. cerevisiae) | 2100 | 0.091 | 0.6214 | Yes |
| 12 | GRPEL1 | GRPEL1 Entrez, Source | GrpE-like 1, mitochondrial (E. coli) | 2691 | 0.074 | 0.6144 | No |
| 13 | ATP5F1 | ATP5F1 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B1 | 3842 | 0.049 | 0.5530 | No |
| 14 | DBT | DBT Entrez, Source | dihydrolipoamide branched chain transacylase E2 | 3912 | 0.048 | 0.5722 | No |
| 15 | CS | CS Entrez, Source | citrate synthase | 4175 | 0.043 | 0.5745 | No |
| 16 | ACADM | ACADM Entrez, Source | acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain | 4299 | 0.041 | 0.5862 | No |
| 17 | MRPL23 | MRPL23 Entrez, Source | mitochondrial ribosomal protein L23 | 4352 | 0.040 | 0.6026 | No |
| 18 | MRPL41 | MRPL41 Entrez, Source | mitochondrial ribosomal protein L41 | 4921 | 0.030 | 0.5753 | No |
| 19 | NR3C1 | NR3C1 Entrez, Source | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 5252 | 0.025 | 0.5634 | No |
| 20 | ETFA | ETFA Entrez, Source | electron-transfer-flavoprotein, alpha polypeptide (glutaric aciduria II) | 5336 | 0.024 | 0.5694 | No |
| 21 | TIMM44 | TIMM44 Entrez, Source | translocase of inner mitochondrial membrane 44 homolog (yeast) | 8155 | -0.017 | 0.3665 | No |
| 22 | MRPS18A | MRPS18A Entrez, Source | mitochondrial ribosomal protein S18A | 9675 | -0.045 | 0.2753 | No |
