Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | MONOOXYGENASE_ACTIVITY |
| Enrichment Score (ES) | 0.7106589 |
| Normalized Enrichment Score (NES) | 1.91492 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0061992565 |
| FWER p-Value | 0.39 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CYP17A1 | CYP17A1 Entrez, Source | cytochrome P450, family 17, subfamily A, polypeptide 1 | 14 | 0.733 | 0.2537 | Yes |
| 2 | KMO | KMO Entrez, Source | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | 64 | 0.478 | 0.4161 | Yes |
| 3 | SC4MOL | SC4MOL Entrez, Source | sterol-C4-methyl oxidase-like | 444 | 0.218 | 0.4632 | Yes |
| 4 | CYP26A1 | CYP26A1 Entrez, Source | cytochrome P450, family 26, subfamily A, polypeptide 1 | 562 | 0.191 | 0.5206 | Yes |
| 5 | CYP8B1 | CYP8B1 Entrez, Source | cytochrome P450, family 8, subfamily B, polypeptide 1 | 594 | 0.187 | 0.5831 | Yes |
| 6 | PAH | PAH Entrez, Source | phenylalanine hydroxylase | 628 | 0.182 | 0.6440 | Yes |
| 7 | CYP4F2 | CYP4F2 Entrez, Source | cytochrome P450, family 4, subfamily F, polypeptide 2 | 933 | 0.150 | 0.6734 | Yes |
| 8 | CYP1B1 | CYP1B1 Entrez, Source | cytochrome P450, family 1, subfamily B, polypeptide 1 | 1078 | 0.138 | 0.7107 | Yes |
| 9 | CYP11B1 | CYP11B1 Entrez, Source | cytochrome P450, family 11, subfamily B, polypeptide 1 | 1789 | 0.102 | 0.6926 | No |
| 10 | CYP27A1 | CYP27A1 Entrez, Source | cytochrome P450, family 27, subfamily A, polypeptide 1 | 2033 | 0.093 | 0.7067 | No |
| 11 | NOS1 | NOS1 Entrez, Source | nitric oxide synthase 1 (neuronal) | 2908 | 0.069 | 0.6649 | No |
| 12 | FMO2 | FMO2 Entrez, Source | flavin containing monooxygenase 2 (non-functional) | 4969 | 0.030 | 0.5206 | No |
| 13 | TH | TH Entrez, Source | tyrosine hydroxylase | 5089 | 0.028 | 0.5214 | No |
| 14 | FMO1 | FMO1 Entrez, Source | flavin containing monooxygenase 1 | 5137 | 0.027 | 0.5273 | No |
| 15 | CYP19A1 | CYP19A1 Entrez, Source | cytochrome P450, family 19, subfamily A, polypeptide 1 | 6596 | 0.005 | 0.4197 | No |
| 16 | CYP7B1 | CYP7B1 Entrez, Source | cytochrome P450, family 7, subfamily B, polypeptide 1 | 9114 | -0.034 | 0.2427 | No |
| 17 | CYP3A4 | CYP3A4 Entrez, Source | cytochrome P450, family 3, subfamily A, polypeptide 4 | 10311 | -0.059 | 0.1736 | No |
| 18 | NOS3 | NOS3 Entrez, Source | nitric oxide synthase 3 (endothelial cell) | 12369 | -0.155 | 0.0730 | No |
