Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | MPRPATHWAY |
| Enrichment Score (ES) | -0.80723554 |
| Normalized Enrichment Score (NES) | -1.9406961 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.013096814 |
| FWER p-Value | 0.371 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PRKAR2A | PRKAR2A Entrez, Source | protein kinase, cAMP-dependent, regulatory, type II, alpha | 2568 | 0.078 | -0.1735 | No |
| 2 | GNAS | GNAS Entrez, Source | GNAS complex locus | 2815 | 0.071 | -0.1744 | No |
| 3 | HRAS | HRAS Entrez, Source | v-Ha-ras Harvey rat sarcoma viral oncogene homolog | 4923 | 0.030 | -0.3250 | No |
| 4 | RPS6KA1 | RPS6KA1 Entrez, Source | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 5488 | 0.022 | -0.3619 | No |
| 5 | MAPK1 | MAPK1 Entrez, Source | mitogen-activated protein kinase 1 | 9755 | -0.047 | -0.6704 | No |
| 6 | PRKAR1A | PRKAR1A Entrez, Source | protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) | 10251 | -0.058 | -0.6932 | No |
| 7 | SRC | SRC Entrez, Source | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 11494 | -0.099 | -0.7619 | No |
| 8 | GNB1 | GNB1 Entrez, Source | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 12099 | -0.132 | -0.7747 | Yes |
| 9 | MAPK3 | MAPK3 Entrez, Source | mitogen-activated protein kinase 3 | 12441 | -0.162 | -0.7602 | Yes |
| 10 | CAP1 | CAP1 Entrez, Source | CAP, adenylate cyclase-associated protein 1 (yeast) | 12826 | -0.231 | -0.7319 | Yes |
| 11 | PRKAR1B | PRKAR1B Entrez, Source | protein kinase, cAMP-dependent, regulatory, type I, beta | 12903 | -0.254 | -0.6750 | Yes |
| 12 | PRKAR2B | PRKAR2B Entrez, Source | protein kinase, cAMP-dependent, regulatory, type II, beta | 13042 | -0.314 | -0.6077 | Yes |
| 13 | CCNB1 | CCNB1 Entrez, Source | cyclin B1 | 13131 | -0.385 | -0.5193 | Yes |
| 14 | GNAI1 | GNAI1 Entrez, Source | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 13262 | -0.580 | -0.3858 | Yes |
| 15 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 13340 | -1.586 | 0.0002 | Yes |
