Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | MYOD_NIH3T3_UP |
| Enrichment Score (ES) | -0.5786356 |
| Normalized Enrichment Score (NES) | -1.8218251 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.032787547 |
| FWER p-Value | 0.91 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | HMGCS2 | HMGCS2 Entrez, Source | 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial) | 117 | 0.396 | 0.0359 | No |
| 2 | VKORC1 | VKORC1 Entrez, Source | vitamin K epoxide reductase complex, subunit 1 | 275 | 0.277 | 0.0553 | No |
| 3 | LRP4 | LRP4 Entrez, Source | low density lipoprotein receptor-related protein 4 | 323 | 0.258 | 0.0809 | No |
| 4 | HRC | HRC Entrez, Source | histidine rich calcium binding protein | 439 | 0.219 | 0.0969 | No |
| 5 | TFRC | TFRC Entrez, Source | transferrin receptor (p90, CD71) | 608 | 0.185 | 0.1052 | No |
| 6 | GADD45G | GADD45G Entrez, Source | growth arrest and DNA-damage-inducible, gamma | 829 | 0.160 | 0.1066 | No |
| 7 | PDLIM3 | PDLIM3 Entrez, Source | PDZ and LIM domain 3 | 2579 | 0.077 | -0.0163 | No |
| 8 | RB1 | RB1 Entrez, Source | retinoblastoma 1 (including osteosarcoma) | 2765 | 0.072 | -0.0221 | No |
| 9 | RHOB | RHOB Entrez, Source | ras homolog gene family, member B | 2800 | 0.071 | -0.0166 | No |
| 10 | HSPB8 | HSPB8 Entrez, Source | heat shock 22kDa protein 8 | 3246 | 0.061 | -0.0431 | No |
| 11 | AKT2 | AKT2 Entrez, Source | v-akt murine thymoma viral oncogene homolog 2 | 3361 | 0.059 | -0.0451 | No |
| 12 | ENO3 | ENO3 Entrez, Source | enolase 3 (beta, muscle) | 3849 | 0.049 | -0.0762 | No |
| 13 | IGFBP5 | IGFBP5 Entrez, Source | insulin-like growth factor binding protein 5 | 4057 | 0.045 | -0.0867 | No |
| 14 | TNNT2 | TNNT2 Entrez, Source | troponin T type 2 (cardiac) | 4891 | 0.031 | -0.1459 | No |
| 15 | CHRNA1 | CHRNA1 Entrez, Source | cholinergic receptor, nicotinic, alpha 1 (muscle) | 5541 | 0.021 | -0.1923 | No |
| 16 | HES6 | HES6 Entrez, Source | hairy and enhancer of split 6 (Drosophila) | 6341 | 0.009 | -0.2514 | No |
| 17 | TNNT3 | TNNT3 Entrez, Source | troponin T type 3 (skeletal, fast) | 6538 | 0.006 | -0.2655 | No |
| 18 | MYOD1 | MYOD1 Entrez, Source | myogenic differentiation 1 | 7324 | -0.005 | -0.3240 | No |
| 19 | TNNI2 | TNNI2 Entrez, Source | troponin I type 2 (skeletal, fast) | 7460 | -0.007 | -0.3334 | No |
| 20 | ATP1A1 | ATP1A1 Entrez, Source | ATPase, Na+/K+ transporting, alpha 1 polypeptide | 7578 | -0.009 | -0.3413 | No |
| 21 | PPFIA4 | PPFIA4 Entrez, Source | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 7620 | -0.009 | -0.3433 | No |
| 22 | MYBPH | MYBPH Entrez, Source | myosin binding protein H | 7699 | -0.010 | -0.3480 | No |
| 23 | STK17B | STK17B Entrez, Source | serine/threonine kinase 17b (apoptosis-inducing) | 7803 | -0.012 | -0.3544 | No |
| 24 | MYOG | MYOG Entrez, Source | myogenin (myogenic factor 4) | 7858 | -0.013 | -0.3570 | No |
| 25 | NAV2 | NAV2 Entrez, Source | neuron navigator 2 | 8223 | -0.018 | -0.3823 | No |
| 26 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 8319 | -0.020 | -0.3872 | No |
| 27 | ATP2A1 | ATP2A1 Entrez, Source | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 | 8368 | -0.021 | -0.3884 | No |
| 28 | CKM | CKM Entrez, Source | creatine kinase, muscle | 8557 | -0.024 | -0.3999 | No |
| 29 | MYH3 | MYH3 Entrez, Source | myosin, heavy chain 3, skeletal muscle, embryonic | 8743 | -0.027 | -0.4107 | No |
| 30 | CHRNG | CHRNG Entrez, Source | cholinergic receptor, nicotinic, gamma | 9124 | -0.035 | -0.4354 | No |
| 31 | HIP1 | HIP1 Entrez, Source | huntingtin interacting protein 1 | 9248 | -0.037 | -0.4405 | No |
| 32 | KIFC3 | KIFC3 Entrez, Source | kinesin family member C3 | 9267 | -0.037 | -0.4377 | No |
| 33 | PSMC3 | PSMC3 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 3 | 9750 | -0.047 | -0.4687 | No |
| 34 | CCND3 | CCND3 Entrez, Source | cyclin D3 | 9869 | -0.049 | -0.4720 | No |
| 35 | KLHL5 | KLHL5 Entrez, Source | kelch-like 5 (Drosophila) | 9873 | -0.049 | -0.4667 | No |
| 36 | CUGBP1 | CUGBP1 Entrez, Source | CUG triplet repeat, RNA binding protein 1 | 10236 | -0.058 | -0.4875 | No |
| 37 | CD82 | CD82 Entrez, Source | CD82 molecule | 10257 | -0.058 | -0.4824 | No |
| 38 | ANXA11 | ANXA11 Entrez, Source | annexin A11 | 10458 | -0.063 | -0.4904 | No |
| 39 | PVR | PVR Entrez, Source | poliovirus receptor | 11445 | -0.097 | -0.5536 | No |
| 40 | DCAKD | DCAKD Entrez, Source | dephospho-CoA kinase domain containing | 11563 | -0.102 | -0.5508 | No |
| 41 | CCDC23 | CCDC23 Entrez, Source | coiled-coil domain containing 23 | 11830 | -0.115 | -0.5579 | No |
| 42 | KLF5 | KLF5 Entrez, Source | Kruppel-like factor 5 (intestinal) | 12107 | -0.132 | -0.5638 | Yes |
| 43 | HS2ST1 | HS2ST1 Entrez, Source | heparan sulfate 2-O-sulfotransferase 1 | 12206 | -0.140 | -0.5553 | Yes |
| 44 | PBXIP1 | PBXIP1 Entrez, Source | pre-B-cell leukemia transcription factor interacting protein 1 | 12303 | -0.149 | -0.5458 | Yes |
| 45 | BIN1 | BIN1 Entrez, Source | bridging integrator 1 | 12397 | -0.157 | -0.5351 | Yes |
| 46 | GPC1 | GPC1 Entrez, Source | glypican 1 | 12419 | -0.160 | -0.5185 | Yes |
| 47 | CHRNB1 | CHRNB1 Entrez, Source | cholinergic receptor, nicotinic, beta 1 (muscle) | 12746 | -0.213 | -0.5190 | Yes |
| 48 | PRKAR2B | PRKAR2B Entrez, Source | protein kinase, cAMP-dependent, regulatory, type II, beta | 13042 | -0.314 | -0.5058 | Yes |
| 49 | RUNX1 | RUNX1 Entrez, Source | runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) | 13073 | -0.336 | -0.4702 | Yes |
| 50 | SCHIP1 | SCHIP1 Entrez, Source | schwannomin interacting protein 1 | 13180 | -0.438 | -0.4288 | Yes |
| 51 | PRSS23 | PRSS23 Entrez, Source | protease, serine, 23 | 13276 | -0.650 | -0.3626 | Yes |
| 52 | PRND | PRND Entrez, Source | prion protein 2 (dublet) | 13296 | -0.733 | -0.2814 | Yes |
| 53 | DBN1 | DBN1 Entrez, Source | drebrin 1 | 13318 | -0.939 | -0.1771 | Yes |
| 54 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 13340 | -1.586 | 0.0002 | Yes |
