Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | NO1PATHWAY |
| Enrichment Score (ES) | -0.6257108 |
| Normalized Enrichment Score (NES) | -1.7110045 |
| Nominal p-value | 0.014925373 |
| FDR q-value | 0.059532974 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | VEGF | VEGF Entrez, Source | vascular endothelial growth factor | 901 | 0.153 | -0.0268 | No |
| 2 | PDE3A | PDE3A Entrez, Source | phosphodiesterase 3A, cGMP-inhibited | 1751 | 0.103 | -0.0629 | No |
| 3 | PRKAR2A | PRKAR2A Entrez, Source | protein kinase, cAMP-dependent, regulatory, type II, alpha | 2568 | 0.078 | -0.1034 | No |
| 4 | TNNI1 | TNNI1 Entrez, Source | troponin I type 1 (skeletal, slow) | 3145 | 0.063 | -0.1297 | No |
| 5 | CHRM1 | CHRM1 Entrez, Source | cholinergic receptor, muscarinic 1 | 4018 | 0.046 | -0.1828 | No |
| 6 | FLT4 | FLT4 Entrez, Source | fms-related tyrosine kinase 4 | 4331 | 0.041 | -0.1954 | No |
| 7 | SLC7A1 | SLC7A1 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 4346 | 0.040 | -0.1856 | No |
| 8 | CHRNA1 | CHRNA1 Entrez, Source | cholinergic receptor, nicotinic, alpha 1 (muscle) | 5541 | 0.021 | -0.2696 | No |
| 9 | BDKRB2 | BDKRB2 Entrez, Source | bradykinin receptor B2 | 5599 | 0.020 | -0.2684 | No |
| 10 | RYR2 | RYR2 Entrez, Source | ryanodine receptor 2 (cardiac) | 5963 | 0.015 | -0.2917 | No |
| 11 | FLT1 | FLT1 Entrez, Source | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 7411 | -0.006 | -0.3988 | No |
| 12 | PDE3B | PDE3B Entrez, Source | phosphodiesterase 3B, cGMP-inhibited | 8189 | -0.018 | -0.4523 | No |
| 13 | PRKG2 | PRKG2 Entrez, Source | protein kinase, cGMP-dependent, type II | 10186 | -0.056 | -0.5872 | Yes |
| 14 | PRKAR1A | PRKAR1A Entrez, Source | protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) | 10251 | -0.058 | -0.5765 | Yes |
| 15 | PDE2A | PDE2A Entrez, Source | phosphodiesterase 2A, cGMP-stimulated | 10423 | -0.062 | -0.5727 | Yes |
| 16 | AKT1 | AKT1 Entrez, Source | v-akt murine thymoma viral oncogene homolog 1 | 10634 | -0.068 | -0.5703 | Yes |
| 17 | CALM1 | CALM1 Entrez, Source | calmodulin 1 (phosphorylase kinase, delta) | 10814 | -0.073 | -0.5643 | Yes |
| 18 | CALM3 | CALM3 Entrez, Source | calmodulin 3 (phosphorylase kinase, delta) | 11285 | -0.090 | -0.5755 | Yes |
| 19 | KDR | KDR Entrez, Source | kinase insert domain receptor (a type III receptor tyrosine kinase) | 11669 | -0.108 | -0.5754 | Yes |
| 20 | CALM2 | CALM2 Entrez, Source | calmodulin 2 (phosphorylase kinase, delta) | 12340 | -0.152 | -0.5850 | Yes |
| 21 | NOS3 | NOS3 Entrez, Source | nitric oxide synthase 3 (endothelial cell) | 12369 | -0.155 | -0.5456 | Yes |
| 22 | SYT1 | SYT1 Entrez, Source | synaptotagmin I | 12373 | -0.155 | -0.5043 | Yes |
| 23 | PRKAR1B | PRKAR1B Entrez, Source | protein kinase, cAMP-dependent, regulatory, type I, beta | 12903 | -0.254 | -0.4761 | Yes |
| 24 | PRKAR2B | PRKAR2B Entrez, Source | protein kinase, cAMP-dependent, regulatory, type II, beta | 13042 | -0.314 | -0.4023 | Yes |
| 25 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 13340 | -1.586 | 0.0002 | Yes |
