Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | NUCLEAR_RECEPTORS |
| Enrichment Score (ES) | 0.6138427 |
| Normalized Enrichment Score (NES) | 1.8403007 |
| Nominal p-value | 0.0068649887 |
| FDR q-value | 0.011015424 |
| FWER p-Value | 0.743 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | NR1I3 | NR1I3 Entrez, Source | nuclear receptor subfamily 1, group I, member 3 | 73 | 0.449 | 0.1343 | Yes |
| 2 | NR5A2 | NR5A2 Entrez, Source | nuclear receptor subfamily 5, group A, member 2 | 206 | 0.307 | 0.2201 | Yes |
| 3 | RARB | RARB Entrez, Source | retinoic acid receptor, beta | 214 | 0.304 | 0.3143 | Yes |
| 4 | RXRG | RXRG Entrez, Source | retinoid X receptor, gamma | 499 | 0.203 | 0.3562 | Yes |
| 5 | RXRA | RXRA Entrez, Source | retinoid X receptor, alpha | 566 | 0.190 | 0.4104 | Yes |
| 6 | NR1H3 | NR1H3 Entrez, Source | nuclear receptor subfamily 1, group H, member 3 | 583 | 0.188 | 0.4678 | Yes |
| 7 | HNF4A | HNF4A Entrez, Source | hepatocyte nuclear factor 4, alpha | 626 | 0.183 | 0.5215 | Yes |
| 8 | NR1I2 | NR1I2 Entrez, Source | nuclear receptor subfamily 1, group I, member 2 | 855 | 0.157 | 0.5534 | Yes |
| 9 | PPARA | PPARA Entrez, Source | peroxisome proliferative activated receptor, alpha | 1252 | 0.127 | 0.5631 | Yes |
| 10 | PPARD | PPARD Entrez, Source | peroxisome proliferative activated receptor, delta | 1387 | 0.119 | 0.5902 | Yes |
| 11 | VDR | VDR Entrez, Source | vitamin D (1,25- dihydroxyvitamin D3) receptor | 1535 | 0.111 | 0.6138 | Yes |
| 12 | NR4A2 | NR4A2 Entrez, Source | nuclear receptor subfamily 4, group A, member 2 | 2245 | 0.086 | 0.5875 | No |
| 13 | THRB | THRB Entrez, Source | thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian) | 2315 | 0.085 | 0.6087 | No |
| 14 | PPARG | PPARG Entrez, Source | peroxisome proliferative activated receptor, gamma | 3592 | 0.054 | 0.5296 | No |
| 15 | ESR2 | ESR2 Entrez, Source | estrogen receptor 2 (ER beta) | 4553 | 0.037 | 0.4690 | No |
| 16 | THRA | THRA Entrez, Source | thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian) | 4857 | 0.032 | 0.4561 | No |
| 17 | ESRRA | ESRRA Entrez, Source | estrogen-related receptor alpha | 5141 | 0.027 | 0.4433 | No |
| 18 | NR3C1 | NR3C1 Entrez, Source | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 5252 | 0.025 | 0.4429 | No |
| 19 | NR4A1 | NR4A1 Entrez, Source | nuclear receptor subfamily 4, group A, member 1 | 5523 | 0.021 | 0.4293 | No |
| 20 | NR2C2 | NR2C2 Entrez, Source | nuclear receptor subfamily 2, group C, member 2 | 6625 | 0.005 | 0.3481 | No |
| 21 | NPM1 | NPM1 Entrez, Source | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 7074 | -0.001 | 0.3149 | No |
| 22 | NR2F2 | NR2F2 Entrez, Source | nuclear receptor subfamily 2, group F, member 2 | 7382 | -0.006 | 0.2936 | No |
| 23 | PGR | PGR Entrez, Source | progesterone receptor | 7642 | -0.010 | 0.2771 | No |
| 24 | NR1D2 | NR1D2 Entrez, Source | nuclear receptor subfamily 1, group D, member 2 | 7779 | -0.012 | 0.2706 | No |
| 25 | RARA | RARA Entrez, Source | retinoic acid receptor, alpha | 8106 | -0.016 | 0.2512 | No |
| 26 | NR2F1 | NR2F1 Entrez, Source | nuclear receptor subfamily 2, group F, member 1 | 8175 | -0.018 | 0.2515 | No |
| 27 | RXRB | RXRB Entrez, Source | retinoid X receptor, beta | 9083 | -0.034 | 0.1939 | No |
| 28 | NR0B1 | NR0B1 Entrez, Source | nuclear receptor subfamily 0, group B, member 1 | 9783 | -0.047 | 0.1562 | No |
| 29 | NR2F6 | NR2F6 Entrez, Source | nuclear receptor subfamily 2, group F, member 6 | 9842 | -0.049 | 0.1670 | No |
| 30 | NR1H2 | NR1H2 Entrez, Source | nuclear receptor subfamily 1, group H, member 2 | 9954 | -0.051 | 0.1746 | No |
| 31 | ESR1 | ESR1 Entrez, Source | estrogen receptor 1 | 9961 | -0.051 | 0.1901 | No |
| 32 | AR | AR Entrez, Source | androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease) | 10940 | -0.077 | 0.1405 | No |
| 33 | ALK | ALK Entrez, Source | anaplastic lymphoma kinase (Ki-1) | 12048 | -0.128 | 0.0972 | No |
